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指挥控制与仿真 2022年第4期44卷 1-7页

作者：岳丽军王凡赵朝先中国人民解放军91977部队北京102249 江苏自动化研究所江苏连云港222061

分析了无人作战平台的能力特点,设想了无人作战体系在海战场中的协同应用场景,设计了无人作战体系的指挥控制系统组成与指挥控制结构,对无人作战体系指挥控制中的主要关键技术进行了分析,促进无人作战平台在海战场中的协同作战应用。

关键词：无人作战体系海战场指挥控制自主协同

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马兜铃酸毒副作用研究概述

中国药物评价 2021年第5期38卷 405-408页

作者：姜峰岳丽君朱丹中央民族大学医院北京100081 中央民族大学药学院北京100081

马兜铃酸广泛存在于马兜铃科马兜铃属及细辛属等植物中,自上世纪90年代“马兜铃酸肾病”事件以来,因其肾毒性、肝毒性及致突变性引起社会关注。本文从实验室研究、临床研究、毒理机制和减毒研究四个方面,探讨近年来马兜铃酸毒副作用研... 详细信息

马兜铃酸广泛存在于马兜铃科马兜铃属及细辛属等植物中,自上世纪90年代“马兜铃酸肾病”事件以来,因其肾毒性、肝毒性及致突变性引起社会关注。本文从实验室研究、临床研究、毒理机制和减毒研究四个方面,探讨近年来马兜铃酸毒副作用研究现状,为安全使用含马兜铃酸类药物提供参考。

关键词：马兜铃酸毒副作用研究进展

Single-cell omics: experimental workflow, data analyses and applications

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Science China life Sciences 2025年第1期68卷 5-102页

作者： Fengying Sun Haoyan li Dongqing Sun Shaliu Fu Lei Gu Xin Shao Qinqin Wang Xin Dong Bin Duan Feiyang Xing jun Wu Minmin Xiao Fangqing Zhao Jing-Dong J.Han Qi liu Xiaohui Fan Chen li Chenfei Wang Tieliu Shi Department of Clinical Laboratory the Affiliated Wuhu Hospital of East China Normal University (The Second People's Hospital of Wuhu City) Pharmaceutical Informatics Institute College of Pharmaceutical SciencesZhejiang University Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration (Tongji University) Ministry of EducationOrthopaedic DepartmentTongji HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Frontier Science Center for Stem Cells School of Life Sciences and TechnologyTongji University Translational Medical Center for Stem Cell Therapy and Institute for Regenerative Medicine Shanghai East HospitalBioinformatics DepartmentSchool of Life Sciences and TechnologyTongji University Research Institute of Intelligent Computing Zhejiang Lab Shanghai Research Institute for Intelligent Autonomous Systems Center for Single-cell Omics School of Public HealthShanghai Jiao Tong University School of Medicine National Key Laboratory of Chinese Medicine Modernization Innovation Center of Yangtze River DeltaZhejiang University Center for Bioinformatics and Computational Biology Shanghai Key Laboratory of Regulatory Biologythe Institute of Biomedical Sciences and School of Life SciencesEast China Normal University Beijing Institutes of life Science Chinese Academy of Sciences Peking-Tsinghua Center for life Sciences Academy for Advanced Interdisciplinary StudiesCenter for Quantitative Biology (CQB)Peking University Zhejiang Key Laboratory of Precision Diagnosis and Therapy for Major Gynecological Diseases Women's HospitalZhejiang University School of Medicine Key Laboratory of Advanced Theory and Application in Statistics and Data Science-MOE School of StatisticsEast China Normal University

Cells are the fundamental units of biological systems and exhibit unique development trajectories and molecular features. Our exploration of how the genomes orchestrate the formation and maintenance of each cell, and control the cellular phenotypes of various organismsis, is both captivating and intricate. Since the inception of the first single-cell RNA technology, technologies related to single-cell sequencing have experienced rapid advancements in recent years. These technologies have expanded horizontally to include single-cell genome, epigenome,proteome, and metabolome, while vertically, they have progressed to integrate multiple omics data and incorporate additional information such as spatial sc RNA-seq and CRISPR screening. Single-cell omics represent a groundbreaking advancement in the biomedical field,offering profound insights into the understanding of complex diseases, including cancers. Here, we comprehensively summarize recent advances in single-cell omics technologies, with a specific focus on the methodology section. This overview aims to guide researchers in selecting appropriate methods for single-cell sequencing and related data analysis.

关键词： single-cell sequencing genome epigenome proteomics metabolomics multimodal spatial transcriptomics CRISPR screening

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu li-Yun Zhou Xiao Huang Xin-yue li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

二苯羟乙酸-3-喹咛环酯的气相色谱行为研究

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分析试验室 2007年第3期26卷 77-80页

作者：岳丽君曲刚莲闵延琴李善茂马果花解放军疾病预防控制所北京100039 防化指挥工程学院分析中心北京102205

气相色谱进样口的瞬时高温会使二苯羟乙酸-3-喹咛环酯（BZ，C21H23NO3）发生分解，经实验确定分解产物为二苯酮。温度越高，分解程度越严重。为解决此问题，采用冷柱头进样口取代传统的分流／不分流进样口，建立了新的BZ气相色谱测定方... 详细信息

气相色谱进样口的瞬时高温会使二苯羟乙酸-3-喹咛环酯（BZ，C21H23NO3）发生分解，经实验确定分解产物为二苯酮。温度越高，分解程度越严重。为解决此问题，采用冷柱头进样口取代传统的分流／不分流进样口，建立了新的BZ气相色谱测定方法。方法的线性范围为0．098～140．0mg／L；相对标准偏差2．0％；检出限0．098ng。

关键词：二苯羟乙酸-3-喹咛环酯(BZ) 分流/不分流进样口冷柱头进样口气相色谱

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乳腔镜治疗男性特发性乳腺增生症的护理

实用临床护理学电子杂志 2018年第8期3卷 6-6页

作者：岳丽君王雪梅成都军区总医院烧伤整形科

目的探讨乳腔镜手术对治疗男性特发性乳腺增生症后护理方法。方法回顾近3年来本科室采用乳腔镜手术治疗的特发男性乳腺增生症患者15例的护理总结。结果 15例患者均乳房外观保持良好,瘢痕增生较少、较轻,心理状态良好的出院。结论选择合... 详细信息

目的探讨乳腔镜手术对治疗男性特发性乳腺增生症后护理方法。方法回顾近3年来本科室采用乳腔镜手术治疗的特发男性乳腺增生症患者15例的护理总结。结果 15例患者均乳房外观保持良好,瘢痕增生较少、较轻,心理状态良好的出院。结论选择合适的男性乳腺增生患者采用乳腔镜手术治疗后进行良好护理能够在切除增生的乳腺腺体的同时,使患者保持较好的外形效果及心理状态。

关键词：乳腔镜男性特发性乳腺增生症护理

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关于《中国渔业经济》载文的计量分析

中国渔业经济 2007年第4期25卷 58-59页

作者：岳丽君韩淑华李香艳河北科技师范学院河北石家庄066600

本文用文献计量学的统计方法,对《中国渔业经济》2001-2006年的栏目设置、载文量、作者合作度、合著率、高产作者、高产单位及作者地域分布进行了分析研究,以期为《中国渔业经济》的编者、作者、读者提供参考。

关键词：栏目设置载文量合著率合作度

《中国新药与临床杂志》引用中文期刊情况初步调查

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中国新药与临床杂志 2003年第11期22卷 702-703页

作者：荆海燕陶军王月军刘丽岚李成建青岛市药品检验所山东青岛266071 中国人民解放军401医院山东青岛266071

文献计量学调查表明 ,2 0 0 0～ 2 0 0 2年《中国新药与临床杂志》引用中文期刊文献共计 16 33条 ,引自 2 32种期刊 ,其中引次在 8次以上的期刊有34种 ,依次为 :(1)《中国新药与临床杂志》772次 ;(2 )中华神经科杂志 31次 ;(3)中华内科... 详细信息

文献计量学调查表明 ,2 0 0 0～ 2 0 0 2年《中国新药与临床杂志》引用中文期刊文献共计 16 33条 ,引自 2 32种期刊 ,其中引次在 8次以上的期刊有34种 ,依次为 :(1)《中国新药与临床杂志》772次 ;(2 )中华神经科杂志 31次 ;(3)中华内科杂志 2 8次 ;(4)中国新药杂志 2 4次 ;(5 )中华心血管病杂志2 3次等等 ,其中《中国新药与临床杂志》引次最多 ,达 772次 ,占 4 7.2 7% 。

关键词：中文期刊调查计量学方法核心期刊

An SOR Implicit Time-accurate Scheme in Calculating Unsteady Flows

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Chinese Journal of Aeronautics 2007年第3期20卷 202-209页

作者： li yue-jun YAN Chao School of Aeronautic Science and Engineering Beijing University of 4eronautics andAstronautics Beijing 100083 China

A new time-accurate marching scheme for unsteady flow calculations is proposed in the present work. This method is the combination of classical Successive Over-Relaxation （SOR） iteration method and Jacobian matrix diagonally dominant splitting method of LUSGS. One advantage of this algorithm is the second-order accuracy because of no factorization error. Another advantage is the low computational cost because the Jacobian matrices and fluxes are only calculated once in each physical time step. And, the SOR algorithm has better convergence property than Gauss-Seidel. To investigate its accuracy and convergency, several unsteady flow computational tests are carded out by using the proposed SOR algorithm. Roe＇s FDS scheme is used to discritize the inviscid flux terms. Unsteady computational results of SOR are compared with the experiment results and those of Gauss-Seidel, Results reveal that the numerical results agree well with the experimental data and the second-order accuracy can be obtained as the Gauss-Seidel for unsteady flow computations. The impact of SOR factor is investigated for unsteady computations by using different SOR factors in this algorithm to simulate each computational test. Different numbers of inner iterations are needed to converge to the same criterion for different SOR factors and optimal choice of SOR factor can improve the computational efficiency greatly.

关键词： unsteady flow SOR algorithm SOR factor Gauss-Seidel

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新疆阿魏化学成分及药理活性研究进展

国际药学研究杂志 2017年第6期44卷 495-499页

作者：黄雅婷岳丽君申翔宇王坤刘春兰中央民族大学生命与环境科学学院北京100081 中央民族大学北京市食品环境与健康工程技术研究中心北京100081

新疆阿魏(Ferula sinkiangensis ***)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分。目前多采用色谱技术建立指纹图谱实现质量控制。原植物药和特征化合物都具有抑菌、杀虫... 详细信息

新疆阿魏(Ferula sinkiangensis ***)是分布在新疆北部的濒危民族植物药,主要含有倍半萜香豆素、含硫化合物、多糖和芳香族类等多种有效化学成分。目前多采用色谱技术建立指纹图谱实现质量控制。原植物药和特征化合物都具有抑菌、杀虫、抗过敏、抗肿瘤等广泛药理作用。本文主要从资源现状、化学成分、指纹图谱和药理活性等方面对国内外新疆阿魏的研究状况进行综述,为其系统化研究、有效质量控制和高效开发利用提供参考。

关键词：新疆阿魏资源分布化学成分指纹图谱药理活性