检索结果-南通市图书馆

Protein & Cell 2020年第3期11卷 227-229页

作者： Zheying Min yue zhao Jing Hang Yun Ren Tao Tan Yong Fan Yang Yu Key Laboratory for Major Obstetric Diseases of Guangdong Province The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510150China Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology and Key Laboratory of Assisted Reproduction Ministry of EducationCenter for Reproductive MedicineDepartment of Obstetrics and GynecologyPeking University Third HospitalBeijing 100191China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinery StudiesPeking UniversityBeijing 100871China Yunnan Key Laboratory of Primate Biomedical Research Institute of Primate Translational MedicineKunming University of Science and TechnologyKunming 650500China

In the original publication the Fig.2 and the Supplementary Material 1 was *** correct version of Fig.2 and the Supplementary Material are provided in this correction *** should be corrected to PAX6 in Fig.2C legend a... 详细信息

关键词： correction corrected characteristics

Ultra-homogeneous dense Ag nano layer enables long lifespan solid-state lithium metal batteries

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2024年第9期96卷 110-119页

作者： Yaning Liu Tianqi Yang Ruyi Fang Chengwei Lu Ruojian Ma Ke yue Zhen Xiao Xiaozheng Zhou Wenkui Zhang Xinping He Yongping Gan Jun Zhang Xinhui Xia hui Huang Xinyong Tao Yang Xia College of Materials Science and Engineering Zhejiang University of TechnologyHangzhou 310014ZhejiangChina Key Laboratory of Rare Earth Optoelectronic Materials and Devices of Zhejiang Province Institute of Optoelectronic Materials and DevicesChina Jiliang UniversityHangzhou 310018ZhejiangChina

The unstable electrolyte/lithium(Li)anode interface has been one of the key challenges in realizing high energy density solid-state lithium metal batteries(LMBs)***,a dense and uniform silver(Ag)nano interlayer with a thickness of∼35 nm is designed accurately by magnetron sputtering technology to optimize the electrolyte/Li anode *** Ag nano layer reacts with Li metal anode to in-situ form Li-Ag alloy,thus enhancing the physical interfacial contact,and further improving the interfacial wettability and *** particular,the Li-Ag alloy is inclined to form AgLi phase proved by cryo-TEM and DFT,effectively preventing SN from continuously“attacking”the Li metal anode due to the lower adsorption of succinonitrile(SN)molecules on AgLi than that of pure Li metal,thereby significantly reinforcing the interfacial ***,the enhanced physical and chemical stability of electrolyte/Li anode interface promotes the homogeneous deposition of Li^(+)and inhibits the dendrite *** Li-symmetric cell maintains stable operation for up to 1700 h and the cycling stability of LiFePO_(4)|SPE|Li full cell is remarkably improved at room temperature(capacity retention rate of 91.9%for 200 cycles).This work opens an effective way for accurate and controllable interface design of long lifespan solid-state LMBs.

关键词： Silvernano layer Poly(ethylene oxide) Solid polymer electrolyte Succinonitrile Lithium metal battery

在线全文

学校读者我要写书评

暂无评论

小型地下式污水处理厂设计中的关键问题分析

给水排水 2017年第10期43卷 41-45页

作者：赵越上海市政工程设计研究总院(集团)有限公司上海200092

对小型地下污水处理厂的特点和设计要点进行探讨,小型地下污水处理厂地面层面积小,地面设施和建筑占用率高,难以作为公共绿地使用,在设计中应摆脱大型地下污水处理厂将地面层整体利用为绿化公园的思路,发挥其规模小、灵活性高的优势,采... 详细信息

对小型地下污水处理厂的特点和设计要点进行探讨,小型地下污水处理厂地面层面积小,地面设施和建筑占用率高,难以作为公共绿地使用,在设计中应摆脱大型地下污水处理厂将地面层整体利用为绿化公园的思路,发挥其规模小、灵活性高的优势,采用合理加盖形式降低地下结构埋深,提高集约化程度,统筹考虑地面建筑与景观的关系,节约用地,减少造价,提高环境效益。

关键词：地下式污水处理厂设计特点工程造价地面结构

The Zuo Jin Wan Formula increases chemosensitivity of human primary gastric cancer cells by AKT mediated mitochondrial translocation of cofilin-1

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Natural Medicines 2019年第3期17卷 198-208页

作者： SUN Meng-Yao WANG Dan-Dan SUN Jian zhao Xiao-Hua CAI Si WU Qiu-Xue JIE Tao NI Zhen-Hua SUN Jian-yue TANG Qing-Feng Department of Clinical Laboratory and Central Laboratory Putuo Hospital Shanghai University of Traditional Chinese Medicine Institute of Interdisciplinary Medical Sciences Shanghai University of Traditional Chinese Medicine Department of Clinical Laboratory Shuguang Hospital Shanghai University of Traditional Chinese Medicine Department of Pediatrics Putuo Hospital Shanghai University of Traditional Chinese Medicine

Resistance to cisplatin(DDP)-based chemotherapy is a major cause of treatment failure in human gastric cancer(GC). It is necessary to identify the drugs to re-sensitize GC cells to DDP. In our previous research, Zuo Jin Wan Formula(ZJW) has been proved could increase the mitochondrial apoptosis via cofilin-1 in a immortalized cell line, SGC-7901/DDP. Due to the immortalized cells may still difficult highly recapitulate the important molecular events in vivo, primary GC cells model derived from clinical patient was constructed in the present study to further evaluate the effect of ZJW and the underlying molecular mechanism. Immunofluorescent staining was used to indentify primary cultured human GC cells. Western blotting was carried out to detect the protein expression. Cell Counting Kit-8(CCK-8) was used to evaluate cell proliferation. Flow cytometry analysis was performed to assess cell apoptosis. ZJW inhibited proliferation and induced apoptosis in primary DDP-resistant GC cells. Notably, the apoptosis in GC cells was mediated by inducing cofilin-1 mitochondrial translocation, down-regulating Bcl-2 and up-regulating Bax expression. Surprisingly, the level of p-AKT protein was higher in DDP-resistant GC cells than that of the DDP-sensitive GC cells, and the activation of AKT could attenuate ZJW-induced sensitivity to DDP. These data revealed that ZJW can increase the chemosensitivity in DDP-resistant primary GC cells by inducing mitochondrial apoptosis and AKT inactivation. The combining chemotherapy with ZJW may be an effective therapeutic strategy for GC chemoresistance patients.

关键词： Primary GC cells ZJW AKT Chemoresistance

在线全文

学校读者我要写书评

暂无评论

我国居民住宅建筑生活能耗差异性调查研究

北京大学学报（自然科学版） 2018年第1期54卷 162-170页

作者：王悦赵鹏军北京大学城市与环境学院北京100871

对我国南北方10个城镇及农村居民建筑生活能耗进行全面调查,利用调查数据分析我国城乡用能水平与用能方式存在显著差异的主要影响因素。建筑使用能耗主要包括采暖能耗、降温能耗、照明能耗、家用电器能耗以及炊事能耗等5个方面。调查结... 详细信息

对我国南北方10个城镇及农村居民建筑生活能耗进行全面调查,利用调查数据分析我国城乡用能水平与用能方式存在显著差异的主要影响因素。建筑使用能耗主要包括采暖能耗、降温能耗、照明能耗、家用电器能耗以及炊事能耗等5个方面。调查结果表明,电力、天然气、标准煤是三大主要居住能源;采暖、炊事以及家电是主要的能源消耗活动。城镇与农村能耗来源和用能结构存在差异,城镇居民人均生活消费能源是农村的3.2倍。城镇居民建筑用能以燃气和电力为主,北方城镇燃气和电力分别占73%和20%,南方城镇则分别占47%和23%;农村居民建筑用能中,电力和燃煤所占比例较高。研究结果可为我国实施节能优先政策提供一定的参考依据。

关键词：建筑能耗住宅建筑生活能耗城乡差异

Effect of granular shape on radial segregation in a two-dimensional drum

在线全文

学校读者我要写书评

暂无评论

Chinese Physics B 2024年第4期33卷 509-514页

作者：徐悦李然迟志鹏修文正孙其诚杨晖 School of Optical-Electrical and Computer Engineering University of Shanghai for Science and TechnologyShanghai 200093China School of Electrical and Electronic Engineering Shandong University of TechnologyZibo 255049China State Key Laboratory of Hydroscience and Engineering Tsinghua UniversityBeijing 100084China College of Medical Instruments Shanghai University of Medicine and Health SciencesShanghai 201318China

Granular segregation is widely observed in nature and *** research has focused on segregation caused by differences in the size and density of spherical ***,due to the fact that grains typically have different shapes,the focus is shifting towards shape *** this study,experiments are conducted by mixing cubic and spherical *** results indicate that spherical grains gather at the center and cubic grains are distributed around them,and the degree of segregation is *** experiments,a structured analysis of local regions is conducted to explain the inability to form stable segregation patterns with obviously different geometric ***,through simulations,the reasons for the central and peripheral distributions are explained by comparing velocities and the number of collisions of the grains in the flow layer.

关键词： granular materials cubic grains shape segregation segregation mechanism

在线全文

学校读者我要写书评

暂无评论

顾及轨迹压缩的车辆路径查询算法

测绘学报 2023年第3期52卷 501-514页

作者：赵东保邓悦华北水利水电大学测绘与地理信息学院河南郑州450046 河南省地球物理空间信息研究院河南郑州450009

基于位置服务技术的迅猛发展,产生了巨量车辆轨迹数据。为了有效压缩并查询大规模车辆轨迹数据,本文提出一种面向压缩车辆轨迹的路径空间查询算法。本文算法基于Stroke道路层次结构压缩轨迹空间数据,提取关键变速点压缩轨迹时间数据,并... 详细信息

基于位置服务技术的迅猛发展,产生了巨量车辆轨迹数据。为了有效压缩并查询大规模车辆轨迹数据,本文提出一种面向压缩车辆轨迹的路径空间查询算法。本文算法基于Stroke道路层次结构压缩轨迹空间数据,提取关键变速点压缩轨迹时间数据,并构建了一种用于建立轨迹空间和时间数据之间联系的哈希编码,从而实现车辆轨迹的时空数据集成压缩。利用后缀数组对车辆轨迹的基于Stroke路段的压缩编码构建空间索引结构,再以此为基础,设计了车辆轨迹所对应路径的点信息查询算法、相同子路径查询算法和相似路径查询算法。试验结果表明,针对原始轨迹点空间数据,本文的压缩编码方法压缩比可以达到97∶1,与常规的基于路段编码方式相比,本文压缩编码在车辆轨迹的点信息路径查询方面,查询效率可以提升约2倍;在车辆轨迹的相同子路径查询方面,查询效率可以提升约8倍;在车辆轨迹的相似路径查询方面,查询耗时增长率减少了50%。本文算法对于大规模车辆轨迹的数据管理具有十分重要的基础性作用。

关键词：轨迹压缩 Stroke层次结构相同路径查询相似路径查询

维普期刊数据库博看期刊

pH响应嵌段间面交联胶束药物输送体系的制备及应用

在线全文

学校读者我要写书评

暂无评论

高分子材料科学与工程 2020年第12期36卷 116-122页

作者：赵玥冯媛媛唐山学院环境与化学工程系河北唐山063000

利用可逆加成-断裂链转移(RAFT)聚合与开环聚合相结合的方法,合成了4-硝基苯基丙烯酸酯链段为反应位点的嵌段共聚物,利用点击化学原理,选择1,8-辛二胺作为交联剂进行交联反应,制备嵌段间面交联胶束体系。利用核磁共振波谱仪、凝胶渗透... 详细信息

利用可逆加成-断裂链转移(RAFT)聚合与开环聚合相结合的方法,合成了4-硝基苯基丙烯酸酯链段为反应位点的嵌段共聚物,利用点击化学原理,选择1,8-辛二胺作为交联剂进行交联反应,制备嵌段间面交联胶束体系。利用核磁共振波谱仪、凝胶渗透色谱、透射电镜等方法对聚合物相对分子质量及其分布、交联胶束形态进行表征。结果表明,成功合成了嵌段间面交联胶束体系。药物的搭载与释放性能测定及细胞毒性试验分析结果表明,该胶束系统生物相容性好,稳定性高,对阿苯哒唑药物搭载能力可达45%,在酸性环境中,药物缓释过程具有pH响应性。

关键词：可逆加成-断裂链转移聚合开环聚合聚己内酯 4-硝基苯基丙烯酸酯 1,8-辛二胺

Systematic Identification of Acer rubrum bZIP Transcription Factors and Their Potential Role in Anthocyanin Accumulation under Low Temperature with Light

在线全文

学校读者我要写书评

暂无评论

Phyton-International Journal of Experimental Botany 2024年第11期93卷 3109-3130页

作者： yue zhao Shah Faheem Afzal Zhu Chen Khan Arif Kamal Yuzhi Fei Xin Meng Jie Ren Hua Liu School of Forestry&Landscape Architecture Anhui Agricultural UniversityHefei230036China Institute of Agricultural Engineering Anhui Academy of Agricultural SciencesHefei230031China

Acer rubrum is an important garden color-leafed *** leaves will turn red in autumn,which is of great orna-mental *** leaf color change in Acer rubrum is closely associated with anthocyanins *** anthocyanin synthesis and accumulation,various transcription factor families play signiﬁcant regulatory roles,including the basic(region)leucine zipper(bZIP).However,there is no report on the systematic identiﬁcation and functional analysis of the bZIPs in Acer *** this study,137 bZIPs distributed on 29 chromosomes of Acer rubrum were identiﬁed and renamed according to their locations on the *** to the constructed bZIP phylogenetic tree of Arabidopsis thaliana and Acer rubrum,bZIPs were divided into 13 *** pairs of bZIP genes were involved in tandem duplication,and 106 segmental duplication gene pairs were ***-acting elements in the promoter region of these bZIP genes were *** results of promoter analysis showed that many elements were closely related to light conditions,hormone responses,and abiotic stress *** them,the cis-acting elements related to light response were most abundant and *** results of anthocyanin determination showed that anthocyanin contents in the leaves of Acer rubrum increased signiﬁcantly under low temperature with *** addition,gene expression analysis showed that compared to other ArbZIPs,ArbZIP137,ArbZIP136,ArbZIP114,ArbZIP130,and ArbZIP14 showed a more pronounced increase in gene expression both under low-temperature conditions and under light *** the correlation analysis,there was a high correlation between ArbZIPs and several anthocyanin-regulated transcription factors,including ArMYBs,ArbHLH and ***,the bZIP genes in Acer rubrum were identiﬁed and analyzed,providing a foundational basis for future studies on their function and signiﬁcantly enhancing our understanding of the color mechanism of Acer rubrum.

关键词： Acer rubrum bZIP transcription factor light low temperature anthocyanin accumulation

Combination of fire needle and filiform needle for frozen shoulder in different clinical stages

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Acupuncture-Moxibustion 2019年第2期29卷 119-122页

作者： Yan GAO Mei-ying LIU Shuang WANG yue-hui CHEN Jie-ping XIE Mei-qi JI Party School of the Central Committee of CP.C (National Academy of Governance) Beijing 100091China Community Health Service Center Exhibition Road of Xicheng DistrictBeijing 100037 China School of Acupuncture-Moxibustion. Beijing University of Chinese Medicine Beijing 100029 China

Objective:To observe the clinical efficacy of fire needle combined with filiform needle for different clinical stage frozen shoulders,and to choose the best treatment opportunity for clinical treatment of frozen ***:120 patients with frozen shoulders who met the inclusion criteria were numbered according to the visiting *** were randomized into control group(60 cases)and treatment group(60 cases)according to the random number *** groups were treated with filiform needles once every other day and 3 times a week,and a course of treatment included 6 times and 2 courses were *** treatment group was treated by applying a fire needling point bloodletting on the local tender points once a ***ānyú(肩髃 LI 15),Jiānliáo(肩髎 TE 14),Jiānzhēn(肩贞 SI 9),Tiáokǒu(条口 ST 38),and local tender points were taken according to different meridian *** clinical efficacy of the frozen shoulder patients in the two groups in different clinical stages was *** evaluation indicators were scores of pain,joint activity range and activities of daily living,as well as clinical efficacy of traditional Chinese ***:After treatment,the total scores of hundred-mark five-grade in both groups were significantly higher than those before treatment,and the differences were statistically significant(Treatment group82.02 ± 14.23 vs 43.37 ± 22.10,Control group 66.80 ± 18.98 vs 42.67 ± 23.03,both P<0.01),and the total score of the treatment group was significantly higher than the control group(P<0.01).The hundred-mark five-grade assessment scores after treatment in the treatment group during the frozen stage were significantly higher than the control group(77.2± 14.40 vs 68.43 ± 16.94,P<0.01);as to the clinical efficacy,the total effective rate of the treatment group was higher than the control group,and the difference was statistically significant(91.67% vs 76.67%,P<0.01);The total effective rate of the control group in the acute stage and functional rec

关键词： Periarthritis of the shoulder Clinical stage Fire needle Filiform needle