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SPIDER:Speeding up Side-Channel Vulnerability Detection via Test Suite Reduction

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Tsinghua Science and Technology 2023年第1期28卷 47-58页

作者： Fei Yan Rushan Wu Liqiang Zhang yue cao Key Laboratory of Aerospace Information Security and Trusted Computing Ministry of EducationSchool of Cyber Science and EngineeringWuhan UniversityWuhan 430072China

Side-channel attacks allow adversaries to infer sensitive information,such as cryptographic keys or private user data,by monitoring unintentional information leaks of running *** side-channel detection methods can identify numerous potential vulnerabilities in cryptographic implementations with a small amount of execution traces due to the high diffusion of secret inputs in crypto ***,because non-cryptographic programs cover different paths under various sensitive inputs,extending existing tools for identifying information leaks to non-cryptographic applications suffers from either insufficient path coverage or redundant *** address these limitations,we propose a new dynamic analysis framework named SPIDER that uses fuzzing,execution profiling,and clustering for a high path coverage and test suite reduction,and then speeds up the dynamic analysis of side-channel vulnerability detection in non-cryptographic *** analyze eight non-cryptographic programs and ten cryptographic algorithms under SPIDER in a fully automated way,and our results confirm the effectiveness of test suite reduction and the vulnerability detection accuracy of the whole framework.

关键词： side-channel detection test suite reduction dynamic analysis

Towards Practical Distributed Video Coding for Energy-Constrained Networks

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Chinese Journal of Electronics 2016年第1期25卷 121-130页

作者： cao yue GAO Shaoshuai ZHANG Can QIU Gengfeng School of Electronic Electrical and Communication Engineering University of Chinese Academy of Sciences

Most of current distributed video codecs are developed based on the structure of Stanford scheme that employs channel coding like LDPC and Turbo ***, they need many times of iteration and feedback,which bring high decoding complexity and latency that make them less practical in energy-constrained *** this paper, a new distributed video codec based on modulo operation in the pixel domain is proposed, which only needs one feedback request and has a much lower decoding complexity. Mathematical proof of the equivalence between modulo operation and coset partition in the M-ary field is given, which means that the modulo operation in the M-ary field is a good substitute for channel codes in the distributed video coding systems. A system is built based on the proposed scheme. Simulation results show that the proposed scheme outperforms the state-of-the-art distributed video codecs with the decoding complexity as low as 1% to 10% of them.

关键词： Distributed video coding Modulo operation Coset codes Side information

Multifunctional high-fluorine-content molecule with high dipole moment as electrolyte additive for high performance lithium metal batteries

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Rare Metals 2022年第3期41卷 726-729页

作者： Xi Tang Wen-Chao Zhang Liu-yue cao Institute of Environmental Engineering School of Metallurgy and EnvironmentCentral South UniversityChangsha 410083China School of Chemical and Biomolecular Engineering the University of SydneyDarlingtonNSW 2006Australia

Lithium metal batteries (LMBs) have been regarded as the most promising technology beyond lithium-ion batteries to meet the ever-increasing demand for high-energy and highpower secondary battery technologies. Challenges such as poor electrochemical stability of electrolytes, dendritic Li plating, gradual cathode structure degradation.

关键词： battery lithium fluorine

Ingenious Design of Co Al-LDH p-n Heterojunction Based on CuI as Holes Receptor for Photocatalytic Hydrogen Evolution

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Chinese Journal of Structural Chemistry 2022年第6期41卷 79-85页

作者： yue cao Hongqian Gou Pengfei Zhu Zhiliang Jin School of Chemistry and Chemical Engineering Key Laboratory for Chemical Engineering and TechnologyState Ethnic Affairs CommissionNingxia Key Laboratory of Solar Chemical Conversion TechnologyNorth Minzu UniversityYinchuan 750021China School of Environmental Science and Engineering Shaanxi University of Science and TechnologyXi’an 710021China

Reasonable design of heterojunction can greatly improve the photocatalytic hydrogen evolution activity of ***,p-n heterojunction of 2D/3D structure is constructed by the nanosheet of CoAl-LDH and rock-like *** introduction of CuI can make CoAl-LDH disperse better,which brings more reaction sites for the hydrogen evolution ***,the 2D/3D structure is conducive to the construction of p-n heterojunction between the CoAl-LDH and *** optical and electrochemical properties of the material indicate that the separation and transference of photon-generated carriers are promoted by the p-n *** activity of composite catalyst(CI-10)reaches a maximum of 3.59 mmol g^(−1) h^(−1) which is 28.5 times higher than that of ***,the influence of the amount of CuI and pH value on the hydrogen evolution reaction is *** on the band structures of CoAl-LDH and CuI,the mechanism of photocatalytic reaction of CI-10 is *** p-n heterojunction constructed with the CuI as hole receptor provides a new way to enhance the activity of photocatalytic H_(2) evolution.

关键词： CoAl-LDH CuI p-n heterojunction photocatalysis hydrogen production

Mechanism for suspension magnetization roasting of iron ore using straw-type biomass reductant

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International Journal of Mining Science and Technology 2021年第6期31卷 1075-1083页

作者： yue cao Yongsheng Sun Peng Gao yuexin Han Yanjun Li School of Resources and Civil Engineering Northeastern UniversityShenyang 110819China National-local Joint Engineering Research Center of High-efficient Exploitation Technology for Refractory Iron Ore Resources Shenyang 110819China State Key Laboratory of Rolling and Automation Northeastern UniversityShenyang 110819China

As an alternative reductant for fossil fuel in the future,straw-type biomass contributes to emission reduction and green utilization in the suspension roasting *** this study,the influences of the roasting time,roasting temperature and dose of straw-type biomass after suspension magnetization roasting(SMR) and separation were *** optimal conditions were determined to be a roasting time of 7.5 min with a straw-type biomass dose of 20 wt% and a roasting temperature of 800℃ in which an iron grade of 71.07% and recovery of 94.17% were obtained for the iron *** maximum saturation magnetization under optimal conditions was 35.05 A·m^(2)·g^(-1),and the gaseous regulation of the biomass revealed that cumulative reducing gas volume was 293.93 mL at the optimal roasting time of450 *** transformation of hematite to magnetite was detected by X-ray diffraction(XRD).During microstructure evolution,the outer layer consisting of fissures and tiny holes continuously deepened toward the core.

关键词： Straw-type biomass Suspension magnetization roasting Phase conversation Gases analyses Microstructure evolution

Recent advances of neural text generation:Core tasks,datasets,models and challenges

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Science China(Technological Sciences) 2020年第10期63卷 1990-2010页

作者： JIN HanQi cao yue WANG TianMing XING XinYu WAN XiaoJun Wangxuan Institute of Computer Technology Peking UniversityBeijing 100871China Center for Data Science Peking UniversityBeijing 100871China The MOE Key Laboratory of Computational Linguistics Peking UniversityBeijing 100871China

In recent years,deep neural network has achieved great success in solving many natural language processing ***,substantial progress has been made on neural text generation,which takes the linguistic and non-linguistic input,and generates natural language *** survey aims to provide an up-to-date synthesis of core tasks in neural text generation and the architectures adopted to handle these tasks,and draw attention to the challenges in neural text *** first outline the mainstream neural text generation frameworks,and then introduce datasets,advanced models and challenges of four core text generation tasks in detail,including AMR-to-text generation,data-to-text generation,and two text-to-text generation tasks(i.e.,text summarization and paraphrase generation).Finally,we present future research directions for neural text *** survey can be used as a guide and reference for researchers and practitioners in this area.

关键词： natural language generation neural text generation AMR-to-text data-to-text text summarization paraphrase generation

Hepatitis B virus X protein-mediated upregulation of miR-221 activates the CXCL12-CXCR4 axis to promote NKT cells in HBVrelated hepatocellular carcinoma

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BIOCELL 2023年第7期47卷 1537-1548页

作者： yue cao LIN HU YISHU TANG Department of Laboratory Medicine The First Affiliated Hospital of Chongqing Medical UniversityChongqing400016China

Both hepatitis B virus X protein(HBx)and microRNA-221(miR-221)have been implicated in the development of hepatitis B virus(HBV)-related hepatocellular carcinoma(HCC).The present study demonstrates that HBx promotes HCC cell proliferation via the C-X-C motif chemokine ligand 12-C-X-C chemokine receptor type 4(CXCL12-CXCR4)*** predict that HBx/miR-221-mediated CXCL12/CXCR4 signaling induces NKT cells to promote HBV-related ***:After miR-221 mimic,miR-221 mimic negative control,miR-221 inhibitor,miR-221 inhibitor negative control were transfected into cells,the expression of CXCL12 and miR-221 was detected by qPCR and western *** we constructed a stable HBV-HCC cell ***-HCC cells were injected into the nude mice,thus a HBV-HCC mouse model was constructed.Q-PCR and western blot were used to detect the expression of HBx,miR-221,CXCL12 and CXCR4 in tumor *** expression of CXCL12 was detected by immunohistochemistry,and the expression of CXCR4,CD3 and CD56 was detected by *** levels of CXCL12,IL-2 and TNF-αin serum of mice were detected by ***-one patients with HBV-related HCC,61 patients with HBV-related cirrhosis,61 patients with chronic hepatitis B(CHB)and 30 healthy people were ***12,cytokine levels,and clinicopathological parameters were ***:Hepatitis B virus X protein upregulates the expression of miR-221 and CXCL12 in lentivirus(LV5)-HBx-transfected HepG2 *** protein promotes HepG2 cell proliferation in *** protein promoted tumor growth via the miR-221/CXCL12/CXCR4 pathway in a mouse tumor *** protein upregulated natural killer T cell expression via the CXCR4/CXCL12 pathway to promote tumor *** data demonstrated a positive correlation between CXCL12 concentration with Cre levels and Child-Pugh ***12 had an inferior diagnostic efficiency compared to IL-2 and IL-6 for HBV-related ***:We present evidence that HBx/miR-221-mediated CXCL12/CXCR4 sign

关键词： Hepatitis B virus X protein miR-221 Hepatocellular carcinoma CXCL12 NKT

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细胞外囊泡在口腔鳞状细胞癌诊疗中的作用

中国组织工程研究 2025年第7期29卷 1523-1530页

作者：曹玥叶鑫健李碧瑶张苡宁冯剑颖浙江中医药大学口腔医学院浙江省杭州市310053 浙江大学医学院附属口腔医院·浙江大学口腔医学院·浙江省口腔疾病临床医学研究中心·浙江省口腔生物医学研究重点实验室·浙江大学癌症研究院浙江省杭州市310006

背景:细胞外囊泡在不同的生理和病理生理条件下由多种细胞类型(包括肿瘤细胞)分泌到细胞外环境中,存在着广泛的生物学信号及细胞之间的信号传导。肿瘤衍生的细胞外囊泡可能会加剧癌症的进展、存活、侵袭和促进血管生成。目的:综述细胞... 详细信息

背景:细胞外囊泡在不同的生理和病理生理条件下由多种细胞类型(包括肿瘤细胞)分泌到细胞外环境中,存在着广泛的生物学信号及细胞之间的信号传导。肿瘤衍生的细胞外囊泡可能会加剧癌症的进展、存活、侵袭和促进血管生成。目的:综述细胞外囊泡在口腔鳞状细胞癌诊疗中的研究进展。方法:由第一作者在Pub Med、万方和中国知网数据库中进行文献检索,关键词为“EVs,Oral squamous cell carcinoma,Diagnosis and treatment,Biopsy,Tissue engineering”及“细胞外囊泡,口腔鳞状细胞癌,诊疗,活检,组织工程”,最终纳入63篇文献进行分析。结果与结论:(1)在口腔鳞状细胞癌唾液活检中,细胞外囊泡作为肿瘤细胞与周围微环境间的信息传递工具,携带包括可溶性蛋白、脂质、DNA和RNA在内的多种生物分子,对口腔鳞状细胞癌的进展起着至关重要的作用,这些微小囊泡不仅在肿瘤的生长和扩散中扮演着关键角色,还提供了有关肿瘤生物学特性的重要信息。(2)唾液活检作为一种非侵入性诊断方法,通过分析其中的细胞外囊泡,可以为口腔鳞状细胞癌的早期诊断和靶向治疗开辟新的可能性。(3)研究发现,细胞外囊泡内含的生物活性分子,如micro RNAs(mi RNAs)和特定蛋白质,能作为口腔鳞状细胞癌的生物标志物,提高早期诊断的准确性。细胞外囊泡中的特定蛋白质如EHD2,CAVIN1,PF4V1和CXCL7等显示了作为新型预测性生物标志物的潜力。(4)此外,文章还强调了细胞外囊泡在口腔鳞状细胞癌治疗中的应用潜力,通过工程化改造,细胞外囊泡可以作为新一代纳米级药物输送系统,增强肿瘤靶向治疗的效率和特异性。(5)未来的研究将进一步深入探索细胞外囊泡在口腔鳞状细胞癌治疗中的作用及其机制,有望改善患者的生存率和生活质量。

关键词：细胞外囊泡口腔鳞状细胞癌诊疗活检组织工程药物载体 miRNA 外泌体唾液检测顺铂耐药

Overexpression of G10-EPSPS in soybean provides high glyphosate tolerance

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Journal of Integrative Agriculture 2019年第8期18卷 1851-1858页

作者： XIAO Pei-ying LIU Yi cao yue-ping School of Agriculture and Biology Shanghai Jiao Tong University

Glyphosate is a highly efficient, broad-spectrum nonspecific herbicide that inhibits the 5-enolpyruvylshikimate-3-phosphate synthase(EPSPS)-mediated pathway of shikimic acid. The screening of glyphosate-resistant EPSPS gene is a major means for the development of new genetically modified glyphosate-resistant transgenic crop. Currently, the main commercialized glyphosate-resistant soybean contains glyphosate-resistant gene CP4-EPSPS. In this study, a G10-EPSPS gene was reported providing glyphosate resistance in Zhongdou 32. Here, G10-EPSPS gene was introduced into soybeans through Agrobacterium-mediated soybean cotyledon node. PCR, Southern blotting, semi-quantitative RT-PCR, qRT-PCR, and Western blotting were used, and the results revealed that G10-EPSPS had been integrated into the soybean genome and could be expressed steadily at both mRNA and protein levels. In addition, glyphosate resistance analysis showed that the growth of transgenic soybean had not been affected by concentrations of 900 and 2 700 g a.e. ha–1 of glyphosate. All the results indicated that G10-EPSPS could provide high glyphosate resistance in soybeans and be applied in production of glyphosate-resistant soybean.

关键词： glyphosate transgenic soybean G10-EPSPS glyphosate-resistant