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A New Monoterpene Glucoside from the Leaves of Betula platyphylla Suk.

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Chinese Chemical Letters 2001年第4期12卷 343-344页

作者： Su Juan WANG yue hu pei hui Ming huA Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110015

A new monoterpene glucoside. (2E,67.)-2.6-dimethyl-8-beta -D-glucosyloxy-2,6-octadienoic acid, was isolated from the leaves of Betula platyphylla Suk. The structure was established by spectroscopic data.

关键词： Betula platyphylla Suk. monoterpene glucoside leaves.

A New Chromone Derivative from Stellera chamaejasme L

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Chinese Chemical Letters 2002年第8期13卷 738-739页

作者： Bao Min FENG yue hu pei hui Ming huA School of Traditional Chinese Medicines Shenyang Pharmaceutical UniversityShenyang 110016

A new chromone derivative, 3-[1- (2, 4, 6-trihydroxyphenyl) 3-di-(4-hydroxyphenyl) 1-propanone-2-yl] 5,7-dihydroxy-8-di(4-hydroxyphenyl)methyl-4H-1-benzopyran-4-one, named as isomohsenone was isolated from the roots of Stellera chamaejasme L. together with known chamaechromone. Its structure was determined by the analysis of MS and NMR data, especially 2D NMR spectra.

关键词： Stellera chamaejasme L. chromone 3-[1- (2, 4, 6-trihydroxyphenyl) 3-di-(4-hydroxy- phenyl)-1-propanone-2-yl] 5, 7-dihydroxy-8-di-(4-hydroxyphenyl) methyl-4H-1- benzopyran-4- one.

Eremophilane sesquiterenes from the marine fungus Penicillium ***27-2

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Chinese Chemical Letters 2008年第5期19卷 562-564页

作者： Yong Fu huang Li Qiao A. Li Lv yue hu pei Li Tian Department of Plant Pathology College of Agronomy and Biotechnology China Agricultural University Beijing 100094 China School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China College of Chemical Engineering Qingdao University of Science ＆ Technology Qingdao 266061 China

Six eremophilane sesquiterpenes were obtained from a marine fungus Penicillium sp. BL27-2. Their structures were elucidated as 3-acetyl-9, 7 （11）-dien-7a-hydroxy-8-oxoeremophilane （1）, 3-acetyl-13-deoxyphomenone （2）, Sporogen-AO 1 （3）, 7-hydro- xypetasol （4）, 8a-hydroxy-13-deo -xyphomenone （5） and 6-dehydropetasol （6） based on detailed NMR analysis. 1 was a new compound and 2 was obtained as a new natural compound. These compounds were assayed for their cytotoxic activity on P388, A549, HL60, BEL7402 and K562 cell lines by the MTT method. The assay results suggested the epoxide rings in eremophilane molecules were essential for their activity, and acetylation could enhance their activity.

关键词： Marine fungus Eremophilane sesquiterpenes NMR analysis Cytotoxic activity

One new bufadienolide biotransformed from cinobufagin by Cunninghamella elegans

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Chinese Chemical Letters 2008年第3期19卷 299-301页

作者： Li Qiao Yu Zhi Zhou huan Chen Jia Qing Cao yue hu pei School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

Cunninghamella elegans has been employed for the biotransformation of cinobufagin （1） to afford one metabolites. The structure of the transformation product has been characterized as 7β,12β-dihydroxylcinobufagin （2）. Product 2 is a new compound. In vitro cytotoxic activities of the biotransformation product and the substrate-cinobufagin have been assayed against HeLa; they all showed cytotoxic activities.

关键词： Biotransformation Cinobufagin 7β,12β-Dihydroxylcinobufagin Cunninghamella elegans

A New xanthene from Blumea riparia

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Chinese Chemical Letters 2007年第3期18卷 303-305页

作者： Jia Qing Cao Yao Yao huan Chen Li Qiao Yu Zhi Zhou yue hu pei School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China

A new xanthene, named blumeaxanthene, was isolated from Blumea riparia DC. The structure was elucidated on the basis of the data of NMR, MS, IR.

关键词： Blumea riparia DC. Compositae Blumeaxanthene

A New Macrocyclic Trichochecene from Soil Fungus

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Chinese Chemical Letters 2002年第1期13卷 67-68页

作者： Tao WANG Yi ZHANG yue hu pei hui Ming huA Bao Min FENG Department of Natural Products Chemistry Shenyang Pharmaceutical UniversityShenyang 110016

From fermentation broth of soil fungus 254-2 obtained from Yunnan province, a new macrocylic trichochecene was isolated. The structure was determined on the basis of spectroscopic evidences especially the 2-D NMR spe... 详细信息

关键词： Soil fungus macrocyclic trichochecene spectral data.

A new iridoid from Incarvillea delavayi

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Chinese Chemical Letters 2007年第12期18卷 1512-1514页

作者： Tao Lu Wei Dong Zhang yue hu pei Chuan Zhang Jin Cheng Li YunHeng Shen Department of Phytochemistry School of Pharmacy Second Military Medical University Shanghai 200433 China School of Pharmacy Shanghai Jiao tong University Shanghai 200030 China Shenyang Pharmaceutical University Liaoning Province Shenyang 110016 China

A new iridoid was isolated from the 80% ethanol extract of the whole plant of Incarvillea delavayi. Its structure was defined, and named incarvillic acid, on the basis of spectral evidences.

关键词： Incarvillea delavayi Bignoniaceae Iridoid Incarvillic acid

A new cytotoxic caged polyprenylated xanthone from the resin of Garcinia hanburyi

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Chinese Chemical Letters 2008年第10期19卷 1221-1223页

作者： Li Li Wang Zhan Lin Li Yong Peng Xu Xiao Qiu Liu yue hu pei Yong Kui Jing hui Ming hua School of Traditional Chinese Materia Medica Shenyang Pharmaceutical University Shenyang 110016 China School of Life Science and Biopharmaceutics Shenyang Pharmaceutical University Shenyang 110016 China Department of Medicine Mount Sinai School of Medicine NY 10029-6547 USA

A new caged polyprenylated xanthone, gambogic aldehyde （1）, was isolated from the resin of Garcinia hanburyi. Its structure was elucidated on the basis of spectral data including 1D and 2D NMR data. In addition, the... 详细信息

关键词： Garcinia hanburyi Caged polyprenylated xanthone Antiproliferafive ability

NEW COMPOUNDS FROM PEUCEDANUM PRAERUPTORUM

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Chinese Chemical Letters 1993年第1期4卷 37-38页

作者： Ling Yi KONG yue hu pei Xian LI Ting Ru Zhu Research Department of Naturat Medicine Shenyang College of PharmacyShenyang110015

Four new compounds named qianhucoumarins E, F, G and baihuaqianhuoside have been isolated from the root of Peucedanum praeruptorum. Their structures were elucidated by chemical evidences and spectral analysis.

关键词： NEW COMPOUNDS FROM PEUCEDANUM PRAERUPTORUM