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In situ growth of NiS_(2) nanosheet array on Ni foil as cathode to improve the performance of lithium/sodium-sulfur batteries

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Science China(Technological Sciences) 2022年第1期65卷 231-237页

作者： FAN MouPing chen yuanmao KE Xi HUANG ZeXi chen Youchen WU WenLi QU XiaoFeng SHI ZhiCong GUO ZaiPing Smart Energy Research Centre School of Materials and EnergyGuangdong University of TechnologyGuangzhou 510006China Institute for Superconducting and Electronic Materials Australian Institute for Innovative MaterialsUniversity of WollongongInnovation CampusNorth WollongongNSW 2500Australia

The NiS;nanosheet array on Ni foil(NiS2/NF)was prepared using an in situ growth strategy and sulfidation method and was used as the cathode of lithium sulfur *** unique nanostructure of the NiS;nanosheet array can provide abundant active sites for the adsorption and chemical action of *** with the sulfur powder coated pure NF(pure NF-S)for lithium sulfur battery,the sulfur powder coated NiS_(2)/NF(NiS_(2)/NF-S)electrode exhibits superior electrochemical ***,the NiS_(2)/NF-S delivered a high reversible capacity of 1007.5 m Ah g^(-1) at a current density of 0.1 C(1 C=1675 mA g^(-1))and kept 74.5% of the initial capacity at 1.0 C after 200 cycles,indicating the great promise of NiS_(2)/NF-S as the cathode of lithium sulfur *** addition,the NiS_(2)/NF-S electrode also showed satisfactory electrochemical performance when used as the cathode for sodium sulfur battery.

关键词： nickel sulfides lithium sulfur battery sodium sulfur battery nanosheet array structure electrochemical performance

Direct and green repairing of degraded LiCoO2 for reuse in lithium-ion batteries

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National Science Review 2022年第8期9卷 127-137页

作者： Junxiong Wang Qi Zhang Jinzhi Sheng Zheng Liang Jun Ma yuanmao chen Guangmin Zhou Hui-Ming cheng Shenzhen Geim Graphene Center Tsinghua-Berkeley Shenzhen Institute&Tsinghua Shenzhen International Graduate SchoolTsinghua University Frontiers Science Center for Transformative Molecules School of Chemistry and Chemical EngineeringShanghai Jiao Tong University Faculty of Materials Science and Engineering/Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of Sciences

Traditional recycling processes of LiCoO2rely on destructive decomposition, requiring high-temperature roasting or acid leaching to extract valuable Li and Co, which have significant environmental and economic concerns. Herein, a direct repairing method for degraded LiCoO2using a LiCl–CH4N2O deep eutectic solvent（DES） was established. The DES is not used to dissolve LiCoO2but directly serves as a carrier for the selective replenishment of lithium and cobalt. Replenishment of lithium restores LiCoO2at different states of charge to a capacity of 130 m Ah/g（at 0.1 C rate）, while replenishing the cobalt increases the capacity retention rate of 90% after 100 cycles, which is comparable to pristine LiCoO2. The DES is collected and reused multiple times with a high repair efficiency. This process reduces energy consumption by 37.1% and greenhouse gas emissions by 34.8% compared with the current production process of LiCoO2, demonstrating excellent environmental and economic viability.

关键词： spent cathodes lithium-ion batteries LiCoO2 direct repair deep eutectic solvent lattice distortion

东兴边境地区艾滋病流行的潜在危险及预防和控制对策

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旅行医学科学 1998年第1期4卷 18-20页

作者：陈元懋韦建能陈斌轺东兴卫生检疫局

本文针对东兴边境地区首例艾滋病的检出,通过分析其流行病学情况,结合分析东兴特殊的区位,人口构成特点、医疗机构现状、公民的卫生意识及危险行为等,探讨其传染源、传播途径、易感人群中潜在的流行因素,并提出了建设性的预防和控制对策。

关键词：边境地区 HIV感染者流行预防控制

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中越边境东兴口岸国际旅行卫生保健工作初探

旅行医学科学 1998年第1期4卷 6-9页

作者：韦建能陈元懋陈斌轺东兴卫生检疫局

本文作者针对入出境东兴口岸的国际旅行人员的特点,综合分析中国东兴——越南芒街边境地区的地理气候、饮食习俗、卫生状况、疾病流行特征及医疗现状等,探讨可能遇到的危害旅行健康的因素,从保护旅行者身心健康的角度提出了旅行卫生保... 详细信息

本文作者针对入出境东兴口岸的国际旅行人员的特点,综合分析中国东兴——越南芒街边境地区的地理气候、饮食习俗、卫生状况、疾病流行特征及医疗现状等,探讨可能遇到的危害旅行健康的因素,从保护旅行者身心健康的角度提出了旅行卫生保健和咨询构想,并就如何具体、全面实施提出了建设性意见。

关键词：口岸国际旅行卫生保健咨询

Cell polarization in ischemic stroke: molecular mechanisms and advances

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Neural Regeneration Research 2025年第3期20卷 632-645页

作者： Yuanwei Li Xiaoxiao Xu Xuan Wu Jiarui Li Shiling chen Danyang chen Gaigai Li Zhouping Tang Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Ischemic stroke is a cerebrovascular disease associated with high mortality and disability rates. Since the inflammation and immune response play a central role in driving ischemic damage, it becomes essential to modulate excessive inflammatory reactions to promote cell survival and facilitate tissue repair around the injury site. Various cell types are involved in the inflammatory response, including microglia, astrocytes, and neutrophils, each exhibiting distinct phenotypic profiles upon stimulation. They display either proinflammatory or anti-inflammatory states, a phenomenon known as ‘cell polarization.’ There are two cell polarization therapy strategies. The first involves inducing cells into a neuroprotective phenotype in vitro, then reintroducing them autologously. The second approach utilizes small molecular substances to directly affect cells in vivo. In this review, we elucidate the polarization dynamics of the three reactive cell populations(microglia, astrocytes, and neutrophils) in the context of ischemic stroke, and provide a comprehensive summary of the molecular mechanisms involved in their phenotypic switching. By unraveling the complexity of cell polarization, we hope to offer insights for future research on neuroinflammation and novel therapeutic strategies for ischemic stroke.

关键词： astrocyte polarization immune regulation inflammation ischemic injury microglia polarization neutrophil polarization signaling pathways stroke

Brain region-specific roles of brain-derived neurotrophic factor in social stress-induced depressive-like behavior

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Neural Regeneration Research 2025年第1期20卷 159-173页

作者： Man Han Deyang Zeng Wei Tan Xingxing chen Shuyuan Bai Qiong Wu Yushan chen Zhen Wei Yufei Mei Yan Zeng Brain Science and Advanced Technology Institute Wuhan University of Science and TechnologyWuhanHubei ProvinceChina Geriatric Hospital Affiliated to Wuhan University of Science and Technology WuhanHubei ProvinceChina School of Public Health Wuhan University of Science and TechnologyWuhanHubei ProvinceChina

Brain-derived neurotrophic factor is a key factor in stress adaptation and avoidance of a social stress behavioral *** studies have shown that brain-derived neurotrophic factor expression in stressed mice is brain region–specific,particularly involving the corticolimbic system,including the ventral tegmental area,nucleus accumbens,prefrontal cortex,amygdala,and *** how brain-derived neurotrophic factor participates in stress processing in different brain regions will deepen our understanding of social stress *** this review,we discuss the expression and regulation of brain-derived neurotrophic factor in stress-sensitive brain regions closely related to the pathophysiology of *** focused on associated molecular pathways and neural circuits,with special attention to the brain-derived neurotrophic factor–tropomyosin receptor kinase B signaling pathway and the ventral tegmental area–nucleus accumbens dopamine *** determined that stress-induced alterations in brain-derived neurotrophic factor levels are likely related to the nature,severity,and duration of stress,especially in the above-mentioned brain regions of the corticolimbic ***,BDNF might be a biological indicator regulating stress-related processes in various brain regions.

关键词： amygdala chronic mild stress chronic social defeat stress corticolimbic system depression hippocampus medial prefrontal cortex nucleus accumbens social stress models ventral tegmental area

Unraveling the therapeutic potential of Calculus Bovis in liver cancer:A novel step for targeted cancer treatment

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World Journal of Gastroenterology 2025年第3期31卷 127-129页

作者： Xing-Yu chen Xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

Hepatocellular carcinoma is one of the leading causes of cancer-related deaths globally,and effective treatments are urgently *** present study aimed to investigate the inhibitory effect of Calculus Bovis(CB)on liver cancer and the underlying *** inhibited M2 tumor-associated macrophage polarization and modulated the Wnt/β-catenin signaling pathway,thereby suppressing the proliferation of liver cancer *** inhibitory effect on liver cancer growth was confirmed by both in vivo and in vitro experiments(detailed by Huang et al).The present study provides a theoretical basis for the application of CB for the treatment of liver cancer,providing new avenues for liver cancer treatment.

关键词： Calculus Bovis Liver cancer M2 tumor-associated macrophage polarization Wnt/β-catenin Pathway Tumor microenvironment

Soil Nutrient Status and Leaf Nutrient Diagnosis in the Main Apple Producing Regions in China

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Horticultural Plant Journal 2018年第3期4卷 89-93页

作者： GE Shunfeng ZHU Zhanling PENG Ling chen Qian JIANG yuanmao State Key Laboratory of Crop Biology College of Horticulture Science and EngineeringShandong Agricultural University

Soil and leaf nutrient analysis are widely used as effective methods of diagnosing nutrient deficiency in fruit trees,the results of which are used to properly manage fertilizer ***,a survey was conducted for assessment of the soil nutrient status and leaf nutrient concentration in 2 827 apple orchards in the Bohai Bay and Loess Plateau apple production regions of *** soil organic matter,alkali hydrolyzable N,available P,and available K were 10.91 g·kg^(-1),73.21 mg·kg^(-1),70.22 mg·kg^(-1),and 169.23 mg·kg^(-1)in the Bohai Bay region,respectively,and 11.72 g·kg^(-1),56.46 mg·kg^(-1),14.91 mg·kg^(-1),and 135.78 mg·kg^(-1)in the Loess Plateau region,*** organic matter was at a medium-to-low level in both regions,whereas the soil alkali hydrolyzable N was *** the Bohai Bay region,soil available P was high,but soil available K was *** contrast,both soil available P and K were insufficient in the Loess Plateau *** Diagnosis and Recommendation Integrated System(DRIS)diagnostic results indicated that the most deficient elements were Ca and K in low-yielding orchards(<35 t·hm(-2))of the Bohai Bay region followed by Fe,N,and Zn;however in the Loess Plateau region,the most deficient elements were P and K followed by N,Zn,and *** findings imply that the application of Ca,K,Fe,N,and Zn fertilizer should be increased in the Bohai Bay region,whereas P,K,N,Zn,and Cu fertilizer should be enhanced in the Loess Plateau ***,use of organic manure is recommended to improve soil quality in the two apple producing regions.

关键词： apple soil nutrition leaf nutrient nutrient deficiency diagnosis

Toward understanding the role of genomic repeat elements in neurodegenerative diseases

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Neural Regeneration Research 2025年第3期20卷 646-659页

作者： Zhengyu An Aidi Jiang Jingqi chen Institute of Science and Technology for Brain-Inspired Intelligence Fudan UniversityShanghaiChina MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina MOE Key Laboratory of Computational Neuroscience and Brain-Inspired Intelligence Fudan UniversityShanghaiChina Zhangjiang Fudan International Innovation Center ShanghaiChina

Neurodegenerative diseases cause great medical and economic burdens for both patients and society;however, the complex molecular mechanisms thereof are not yet well understood. With the development of high-coverage sequencing technology, researchers have started to notice that genomic repeat regions, previously neglected in search of disease culprits, are active contributors to multiple neurodegenerative diseases. In this review, we describe the association between repeat element variants and multiple degenerative diseases through genome-wide association studies and targeted sequencing. We discuss the identification of disease-relevant repeat element variants, further powered by the advancement of long-read sequencing technologies and their related tools, and summarize recent findings in the molecular mechanisms of repeat element variants in brain degeneration, such as those causing transcriptional silencing or RNA-mediated gain of toxic function. Furthermore, we describe how in silico predictions using innovative computational models, such as deep learning language models, could enhance and accelerate our understanding of the functional impact of repeat element variants. Finally, we discuss future directions to advance current findings for a better understanding of neurodegenerative diseases and the clinical applications of genomic repeat elements.

关键词： Alzheimer's disease ataxia deep learning long-read sequencing neurodegeneration neurodegenerative diseases Parkinson's disease repeat element structural variant