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爆炸切割网络传爆中的间隙与角度效应

火工品 2025年第1期 37-43页

作者：周晓鹏姜勇袁航中国船舶集团有限公司第七一三研究所河南郑州450015 河南省水下智能装备重点实验室河南郑州450015

为研究爆炸切割网络中传爆节点处传爆能力的关键影响因素,通过改变切割索对传爆药柱的传爆间隙进行了平板传爆试验,将试验结果结合仿真分析确定了JO-11C传爆药柱的仿真材料参数,并进一步分析了传播角度对传爆能力的影响。研究结果表明:... 详细信息

为研究爆炸切割网络中传爆节点处传爆能力的关键影响因素,通过改变切割索对传爆药柱的传爆间隙进行了平板传爆试验,将试验结果结合仿真分析确定了JO-11C传爆药柱的仿真材料参数,并进一步分析了传播角度对传爆能力的影响。研究结果表明:随着传爆间隙的增加,传爆能力下降,切割索对传爆药柱的最大传爆间隙区间为2.0~2.5 mm;同时,传爆角度的增大能够显著提高传爆能力。本研究为爆炸切割网络的传爆性能研究以及提高武器系统的可靠性提供了参考。

关键词：爆炸切割网络传爆间隙传爆角度传爆药柱仿真分析

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Role of the globus pallidus in motor and non-motor symptoms of Parkinson's disease

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Neural Regeneration Research 2025年第6期20卷 1628-1643页

作者： Yimiao jiang Zengxin Qi Huixian Zhu Kangli Shen Ruiqi Liu Chenxin Fang Weiwei Lou Yifan jiang Wangrui yuan Xin Cao Liang Chen Qianxing Zhuang Department of Physiology School of MedicineNantong UniversityNantongJiangsu ProvinceChina Department of Neurosurgery Huashan HospitalShanghai Medical CollegeFudan UniversityShanghaiChina National Center for Neurological Disorders ShanghaiChina Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration ShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institute of Brain ScienceFudan UniversityShanghaiChina

The globus pallidus plays a pivotal role in the basal ganglia circuit. Parkinson's disease is characterized by degeneration of dopamine-producing cells in the substantia nigra, which leads to dopamine deficiency in the brain that subsequently manifests as various motor and non-motor symptoms. This review aims to summarize the involvement of the globus pallidus in both motor and non-motor manifestations of Parkinson's disease. The firing activities of parvalbumin neurons in the medial globus pallidus, including both the firing rate and pattern, exhibit strong correlations with the bradykinesia and rigidity associated with Parkinson's disease. Increased beta oscillations, which are highly correlated with bradykinesia and rigidity, are regulated by the lateral globus pallidus. Furthermore,bradykinesia and rigidity are strongly linked to the loss of dopaminergic projections within the cortical-basal ganglia-thalamocortical loop. Resting tremors are attributed to the transmission of pathological signals from the basal ganglia through the motor cortex to the cerebellum-ventral intermediate nucleus circuit. The cortico–striato–pallidal loop is responsible for mediating pallidi-associated sleep disorders. Medication and deep brain stimulation are the primary therapeutic strategies addressing the globus pallidus in Parkinson's disease. Medication is the primary treatment for motor symptoms in the early stages of Parkinson's disease, while deep brain stimulation has been clinically proven to be effective in alleviating symptoms in patients with advanced Parkinson's disease,particularly for the movement disorders caused by levodopa. Deep brain stimulation targeting the globus pallidus internus can improve motor function in patients with tremordominant and non-tremor-dominant Parkinson's disease, while deep brain stimulation targeting the globus pallidus externus can alter the temporal pattern of neural activity throughout the basal ganglia–thalamus network. Therefore, the comp

关键词： anxiety basal ganglia bradykinesia deep brain stimulation depression globus pallidus externus globus pallidus internus lateral globus pallidus medial globus pallidus neural circuit Parkinson's disease

Zinc-based fiber-shaped rechargeable batteries:Insights into structures,electrodes,and electrolytes

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Nano Research 2025年第1期18卷 278-293页

作者： Xuan Zhang Hongcheng Zhang Mengxiang Chen Jingqi Lu Evgeny Zhuravlev Jing jiang Pin Liu Shengyang Dong Du yuan Guoyin Zhu Lianbo Ma Yizhou Zhang Institute of Advanced Materials and Flexible Electronics(IAMFE) School of Chemistry and Materials ScienceNanjing University of Information Science and TechnologyNanjing 210044China School of Materials Science and Engineering Anhui University of TechnologyMaanshan 243002China College of Materials Science and Engineering Changsha University of Science and TechnologyChangsha 410004China

The rapid evolution of flexible wearable electronics has spurred a growing demand for energy storage devices,characterized by low-cost manufacturing processes,high safety standards,exceptional electrochemical performance and robust mechanical *** novel flexible devices,fiber-shaped batteries(FSBs)have emerged as prominent solutions exceptionally suited to future applications,owing to their unique one-dimensional(1D)architecture,remarkable flexibility,potential for miniaturization,adaptability to deformation and compatibility with the conventional textile *** the forefront research on fiber-shaped batteries,zincbased FSBs(ZFSBs)have garnered significant attentions,featured by the promising electrochemical properties of metallic *** enthusiasm is driven by the impressive capacity of Zn(820 mAh·g^(-1))and its low redox potential(Zn/Zn^(2+):-0.76 V *** hydrogen electrode).This review aims to consolidate recent achievements in the structural design,fabrication processes and electrode materials of flexible ***,we highlight three representative structural configurations:parallel type,twisted type and coaxial *** also place special emphasis on electrode modifications and electrolyte ***,we delve into the promising development opportunities and anticipate future challenges associated with ZFSBs,emphasizing their potential roles in powering the next generation of wearable electronics.

关键词： zinc-based batteries fiber-shape parallel type twisted type coaxial type

Inhibition of the cGAS–STING pathway:contributing to the treatment of cerebral ischemia-reperfusion injury

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Neural Regeneration Research 2025年第7期20卷 1900-1918页

作者： hang Yang Yulei Xia Yue Ma Mingtong Gao Shuai Hou Shanshan Xu Yanqiang Wang School of Clinical Medicine Shandong Second Medical UniversityWeifangShandong ProvinceChina Department of Emergency The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina Department of Neurology Ⅱ The Affiliated Hospital of Weifang Medical UniversityWeifangShandong ProvinceChina

The cGAS–STING pathway plays an important role in ischemia-reperfusion injury in the heart,liver,brain,and kidney,but its role and mechanisms in cerebral ischemia-reperfusion injury have not been systematically ***,we outline the components of the cGAS–STING pathway and then analyze its role in autophagy,ferroptosis,cellular pyroptosis,disequilibrium of calcium homeostasis,inflammatory responses,disruption of the blood–brain barrier,microglia transformation,and complement system activation following cerebral ischemia-reperfusion *** further analyze the value of cGAS–STING pathway inhibitors in the treatment of cerebral ischemia-reperfusion injury and conclude that the pathway can regulate cerebral ischemia-reperfusion injury through multiple *** of the cGAS–STING pathway may be helpful in the treatment of cerebral ischemia-reperfusion injury.

关键词： calcium homeostasis cellular autophagy cerebral ischemia-reperfusion injury cGAS–STING pathway ferroptosis gut–brain–microbiota axis inflammatory light chain 3 microglial cells Syntaxin-17 protein

Evaluation of effective spectral features for glacial lake mapping by using Landsat-8 OLI imagery

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Journal of Mountain Science 2020年第11期17卷 2707-2723页

作者： Zhang Mei-mei ZHAO hang CHEN Fang ZENG jiang-yuan Key Laboratory of Digital Earth Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100094China State Key Laboratory of Remote Sensing Science Aerospace Information Research InstituteChinese Academy of SciencesBeijing 100094China Hainan Key Laboratory of Earth Observation Aerospace Information Research InstituteChinese Academy of SciencesSanya 572029China

Glacial lake mapping provides the most feasible way for investigating the water resources and monitoring the flood outburst hazards in High Mountain ***,various types of glacial lakes with different properties bring a constraint to the rapid and accurate glacial lake mapping over a large *** spectral features to map glacial lakes are diverse but some are generally limited to the specific glaciated regions or lake types,some have unclear applicability,which hamper their application for the large *** this end,this study provides a solution for evaluating the most effective spectral features in glacial lake mapping using Landsat-8 *** 23 frequently-used lake mapping spectral features,including single band reflectance features,Water Index features and image transformation features were selected,then the insignificant features were filtered out based on scoring calculated from two classical feature selection methods-random forest and decision tree *** result shows that the three most prominent spectral features(SF)with high scores are NDWI1,EWI,and NDWI3(renamed as SF8,SF19 and SF12 respectively).Accuracy assessment of glacial lake mapping results in five different test sites demonstrate that the selected features performed well and robustly in classifying different types of glacial lakes without any influence from the mountain ***8 and SF19 are superior for the detection of large amount of small glacial lakes,while some lake areas extracted by SF12 are ***,SF8 achieved better accuracy than the other two features in terms of both Kappa Coefficient(0.8812)and Prediction(0.9025),which further indicates that SF8 has great potential for large scale glacial lake mapping in high mountainous area.

关键词： Glacial lake mapping Landsat-8 OLI Water Index Spectral features

PEPFL:A framework for a practical and efficient privacy-preserving federated learning

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Digital Communications and Networks 2024年第2期10卷 355-368页

作者： Yange Chen Baocang Wang hang jiang Pu Duan yuan Ping Zhiyong Hong State Key Laboratory of Integrated Service Networks Xidian UniversityXi'an710071China School of Information Engineering Xuchang UniversityXuchang461000China School of Telecommunications Engineering Xidian UniversityXi'an710071China Secure Collaborative Intelligence Laboratory Ant GroupHangzhou310000China Facility of Intelligence Manufacture Wuyi UniversityJiangmen529020China

As an emerging joint learning model,federated learning is a promising way to combine model parameters of different users for training and inference without collecting users’original ***,a practical and efficient solution has not been established in previous work due to the absence of efficient matrix computation and cryptography schemes in the privacy-preserving federated learning model,especially in partially homomorphic *** this paper,we propose a Practical and Efficient Privacy-preserving Federated Learning(PEPFL)***,we present a lifted distributed ElGamal cryptosystem for federated learning,which can solve the multi-key problem in federated ***,we develop a Practical Partially Single Instruction Multiple Data(PSIMD)parallelism scheme that can encode a plaintext matrix into single plaintext for encryption,improving the encryption efficiency and reducing the communication cost in partially homomorphic *** addition,based on the Convolutional Neural Network(CNN)and the designed cryptosystem,a novel privacy-preserving federated learning framework is designed by using Momentum Gradient Descent(MGD).Finally,we evaluate the security and performance of *** experiment results demonstrate that the scheme is practicable,effective,and secure with low communication and computation costs.

关键词： Federated learning Partially single instruction multiple data Momentum gradient descent ElGamal Multi-key Homomorphic encryption

High-Gain Dual Circularly Polarized Antenna for Air-to-Ground Wireless Link

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Chinese Journal of Electronics 2022年第3期31卷 555-561页

作者： jiang hang YAO yuan XIU Tao CHENG Xiaohe YU Junsheng CHEN Xiaodong School of Electronic Engineering Beijing University of Posts and Telecommunications School of Electronic Engineering and Computer Science Queen Mary University of London

This paper presents an E-band reflector antenna fed by dual circularly polarized feed system. Axial displaced ellipse reflector is adopted for high gain and low blockage mechanisms. The feed system mainly composed of orthomode transducer, iris polarizer and horn antenna, and possesses dual circular polarization. The orthomode transducer offers high isolation performance in broadband by double symmetry and the iris polarizer achieves phase shift by introducing discontinuities. In addition, the ridge and iris in the feed are optimized to be wide enough to fabricate and maintain good mechanical properties in higher frequency band. The entire antenna is simulated and fabricated. The measured gain of 45 ± 1.2 d Bi corresponds to about 52% efficiency. The measured results of reflection coefficients less than-18 d B, isolation over 27 d B, axial-ratio value less than 2.3 d B are achieved from 71 to 86 GHz.

关键词： antenna radiation patterns low blockage mechanisms reflector antennas dual circular polarization high-gain dual circularly polarized antenna horn antennas radio links iris polarizer air-to-ground wireless link orthomode transducer electromagnetic wave polarisation E-band reflector antenna antenna feeds horn antenna high isolation performance dual circularly polarized feed system axial displaced ellipse reflector

Free Vibration Analysis of Moderately-Thick Laminated Doubly-Curved Shells with the Modified Higher-Order Theory

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Acta Mechanica Solida Sinica 2023年第1期36卷 132-142页

作者： yuan Tao Jie Xu Xuegang yuan hang Yin School of Mathematics Boda College of Jilin Normal UniversitySiping 136000China Department of Mechanics Northeastern UniversityShenyang 110819China School of Science Dalian Minzu UniversityDalian 116600China

In this work,the free vibration properties ofmoderately-thick laminated doubly-curved shells are *** model of the natural frequency of the simply-supported laminated doubly-curved shell is formulated via the variational *** on the numerical solutions,the influences of the shell type,the aspect ratio,the lamination angle and the layer number on the free vibration are *** obtained results show that,for the symmetrically laminated curved shells with fixed thickness,when the layer number is greater than 4,the increasing number has no impact on the natural frequency;however,the lamination angle plays a key role in the fundamental frequency of the spherical shell,while it has little effect on the hyperbolic paraboloid ***,a higher-order shear deformation theory with modified parameters is developed for the moderately-thick laminated doubly-curved shells in this work,i.e.,the geometrically nonlinear strain–displacement relationships are derived with a stricter series expansion form,which are more suitable for the moderately-thick curved shells.

关键词： Vibration analysis Laminated doubly-curved shell Modified displacement fields Higher-order shear deformation

Pharmacokinetics and bioequivalence of ranitidine and bismuth derived from two compound preparations

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World Journal of Gastroenterology 2006年第17期12卷 2742-2748页

作者： Quan Zhou Zou-Rong Ruan Hong yuan Bo jiang Dong-hang Xu Department of Clinical Pharmacology the 2^th Affiliated Hospital School of Medicine Zhejiang University Hangzhou 310009 Zhejiang Province China

AIM： To evaluate the bioequivalence of ranitidine and bismuth derived from two compound preparations. METHODS： The bioavailability was measured in 20 healthy male Chinese volunteers following a single oral dose （equivalent to 200 mg of ranitidine and 220 mg of bismuth） of the test or reference products in the fasting state. Then blood samples were collected for 24 h. Plasma concentrations of ranitidine and bismuth were analyzed by high-performance liquid chromatography and inductively coupled plasma-mass spectrometry （ICPMS）, respectively. The non-compartmental method was used for pharmacokinetic analysis. Log-transformed Cmax, AUC（0-t） and AUC（0-∞） were tested for bioequivalence using ANOVA and Schuirmann two-one sided t-test. Tmax was analyzed by Wilcoxon＇s test. RESULTS： Various pharmacokinetic parameters of ranitidine derived from the two compound preparations, including Cmax, AUC（0-t）, AUC（0-∞）, Tmax and T1/2, were nearly consistent with previous observations. These parameters derived from test and reference drug were as follows： Cmax（0.67 ± 0.21 vs 0.68 ± 0.22 mg/L）, AUC（0-t）（3.1 ± 0.6 vs 3.0 ± 0.7 mg/L per hour）, AUC（0-∞）（3.3 ± 0.6 vs 3.2 ± 0.8 mg/L per hour）, Tmax （2.3 ± 0.9 VS 2.1 ± 0.9 h） and T1/2 （2.8 ± 0.3 vs 3.1 ± 0.4 h）. In addition, double-peak absorption profiles of ranitidine were found in some Chinese volunteers. For bismuth, those parameters derived from test and reference drug were as follows： Cmax （11.80 ± 7.36 vs 11.40 ± 6.55 μg/L）, AUC（0-t）（46.65 ± 16.97 vs 47.03 ± 21.49 μg/L per hour）, Tmax （0.50 ± 0.20 vs 0.50 ± 0.20 h） and T1/2 （10.2 ± 2.3 vs 13.0 ± 6.9 h）. Ninety percent of confidence intervals for the test/reference ratio of Cmax, AUC（0-t） and AUC（0-∞） derived from both ranitidine and bismuth were found within the bioequivalence acceptable range of 80%-125%. No significant difference was found in Tmax derived from both ranitidine and bismuth. CONCLUSION： The two compound preparations are bioequivalent and may be prescribed intercha

关键词： Ranitidine Bismuth Compound preparation Bioequivalence Pharmacokinetics Healthy volunteers High-performanace liquid chromatography Inductively coupled plasma-mass spectrometry