检索结果-南通市图书馆

Rise and Fall of the Peer-to-Peer Empire

Tsinghua Science and Technology 2012年第1期17卷 1-16页

作者： Baochun Li yuan feng, bo Li Department of Electrical and Computer Engineering University of Toronto Toronto M5S 3G4 Canada Department of Computer Science Hong Kong University of Science and Technology Hong Kong China

The essence of the peer-to-peer design philosophy is to design protocols for end hosts, or ＂peers＂, to work in collaboration to achieve a certain design objective, such as the sharing of a large file. From a theoretical perspective, it has been recognized that the peer-to-peer design paradigm resembles gossip protocols, and with appropriate algorithmic design, it maximizes the network flow rates in multicast sessions. Over the past ten years, research on peer-to-peer computing and systems, a unique and intriguing category of distributed systems, has received a tremendous amount of research attention from academia and indus-try alike. Peer-to-peer computing eventually culminated in a number of successful commercial systems, showing the viability of their design philosophy in the Internet. The peer-to-peer design paradigm has pushed all design choices of innovative protocols to the edge of the Internet, and in most cases to end hosts themselves. It represents one of the best incarnation of the end-to-end argument, one of the frequently dis-puted design philosophies that guided the design of the Internet. Yet, research on peer-to-peer computing has recently receded from the spotlight, and suffered from a precipitous fall that was as dramatic as its me-teoric rise to the culmination of its popularity. This article presents a cursory glimpse of existing results over the past ten years in peer-to-peer computing, with a particular focus on understanding what has stimulated its rise in popularity, what has contributed to its commercial success, and eventually, what has led to its pre-cipitous fall in research attention. Our insights in this article may be beneficial when we develop our thoughts on the design paradigm of cloud computing.

关键词： peer-to-peer gossip protocols network coding

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Feedforward compensation of the insertion devices effects in the SSRF storage ring

引用

Nuclear Science and Techniques 2022年第6期33卷 34-44页

作者： Xin-Zhong Liu Shun-Qiang Tian Xu Wu Meng Wang Zhen-Tang Zhao bo-yuan feng University of Chinese Academy of Sciences Shanghai 201800China Shanghai Institute of Applied Physics Chinese Academy of SciencesBeijing 100049China Shanghai Advanced Research Institute Chinese Academy of SciencesShanghai 201204China Shanghai University Shanghai 200444China Tsinghua University Beijing 100084China

The lattice of the Shanghai Synchrotron Radiation Facility(SSRF) storage ring was upgraded in the Phase-II beamline project, and thus far, 18 insertion devices(IDs) have been installed. The IDs cause closed-orbit distortions, tune drift, and coupling distortions in the SSRF storage ring, all of which are significant issues that require solutions. In this study, an ID orbit feedforward compensation system based on a response matrix using corrector coils was developed, and it was applied to all commissioned IDs in the SSRF storage ring. After correction, the maximum ID-induced horizontal and vertical orbit distortions were less than 5.0 and 3.5 μm, respectively. Some interesting phenomena observed during the measurement process were explained. Additionally, optical and coupling feedforward systems were developed using quadrupole and skew quadrupole magnets installed on the front and back of elliptically polarizing undulators(EPUs). Moreover, over nearly four months of operation, the developed strategy delivered a satisfactory performance in the SSRF storage ring.

关键词： Shanghai Synchrotron Radiation Facility(SSRF) Insertion devices(IDs) Closed-orbit distortion Tune shift Coupling Feedforward

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Separate calculation of DW-MRI in assessing therapeutic effect in liver tumors in rats

引用

World Journal of Gastroenterology 2013年第47期19卷 9092-9103页

作者： feng Chen Frederik De Keyzer yuan-bo feng Marlein Miranda Cona Jie Yu Guy Marchal Raymond Oyen Yi-Cheng Ni Department of Radiology the First Affiliated HospitalCollege of MedicineZhejiang University Department of Imaging and Pathology University HospitalUniversity of LeuvenHerestraat 49Bus 70033000 LeuvenBelgium

AIM:To explore whether the antitumor effect of a vascular disrupting agent(VDA)would be enhanced by combining with an antiangiogenic agent,and whether such synergistic effects can be effectively evaluated with separate calculation of diffusion weighted magnetic resonance imaging(DW-MRI).METHODS:Thirty-seven rats with implanted liver tumors were randomized into the following three groups:(1)ZD6126,a kind of VDA;(2)ZDTHA,ZD6126 in combination with an antiangiogenic,thalidomide;and(3)*** DW-MRI were performed and quantified before,4 h and 2 d after *** apparent diffusion coefficient(ADC)values were calculated separately for low b values(ADC low),high b values(ADC high)and all b values(ADC all).The tissue perfusion contribution,ADC perf,was calculated as ADC low-ADC *** findings were finally verified by ***:The combination therapy with ZDTHA significantly delayed tumor growth due to synergistic effects by inducing cumulative tumor *** addition to delaying tumor growth,ZDTHA caused tumor necrosis in an additive manner,which was verified by HE *** both ADC high and ADC all in the ZD6126and ZDTHA groups were significantly higher compared to those in the control group on day 2,the entire tumor ADC high of ZDTHA was even higher than that of ZD6126,but the significant difference was not observed for ADCall between ZDTHA and *** indicated that the perfusion insensitive ADC high values calculated from high b value images performed significantly better than ADC all for the monitoring of tumor necrosis on day *** perfusion sensitive ADC perf derived from ADC low by excluding high b value effects could better reflect the reduction of blood flow due to the vessel shutdown induced by ZD6126,compared to the ADC low at 4 *** ADC perf could provide valuable perfusion information from DW-MRI ***:The separate calculation of ADC is more useful than conventional averaged ADC in evaluating

关键词： Diffusion weighted imaging Magnetic resonance imaging Therapeutic assessment Liver tumor Rats Vascular disrupting agent Antiangiogenic agentAnimal model Rodents

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Intra-individual comparison of therapeutic responses to vascular disrupting agent CA4P between rodent primary and secondary liver cancers

引用

World Journal of Gastroenterology 2018年第25期24卷 2710-2721页

作者： Ye-wei Liu Frederik De Keyzer yuan-bo feng feng Chen Shao-li Song Johan Swinnen Guy bormans Raymond Oyen Gang Huang Yi-cheng Ni Shanghai Key Laboratory for Molecular Imaging Shanghai University of Medicine and Health SciencesShanghai 201318China Biomedical Group Campus GasthuisbergKU LeuvenLeuven 3000Belgium Institute of Clinical Nuclear Medicine Renji HospitalShanghai Jiao Tong University School of MedicineShanghai 200127China Shanghai Jiao Tong University School of Medicine(SJTUSM)&Shanghai Institutes for Biological Sciences(SIBS) Chinese Academy of Sciences(CAS)Shanghai 200025China

AIM To compare therapeutic responses of a vascular-disrupting-agent, combretastatin-A4-phosphate(CA4 P), among hepatocellular carcinomas(HCCs) and implanted rhabdomyosarcoma(R1) in the same rats by magneticresonance-imaging(MRI), microangiography and *** Thirty-six HCCs were created by diethylnitrosamine gavage in 14 rats that were also intrahepatically implanted with one R1 per rat as monitored by T2-/T1-weighted images(T2wI/T1wI) on a 3.0 T clinical MRIscanner. Vascular response and tumoral necrosis were detected by dynamic contrast-enhanced(DCE-) and CE-MRI before, 1 h after and 12 h after CA4P iv at 10 mg/kg(treatment group n = 7) or phosphate-buffered saline at 1.0 mL/kg(control group n = 7). Tumor blood supply was calculated by a semiquantitative DCE parameter of area under the time signal intensity curve(AUC30). In vivo MRI findings were verified by postmortem *** On CE-T1wIs, unlike the negative response in all tumors of control animals, in treatment group CA4P caused rapid extensive vascular shutdown in all R1-tumors, but mildly or spottily in HCCs at 1 h. Consequently, tumor necrosis occurred massively in R1-tumors but patchily in HCCs at 12 h. AUC30 revealed vascular closure(66%) in R1-tumors at 1 h(P < 0.05), followed by further perfusion decrease at 12 h(P < 0.01), while less significant vascular clogging occurred in HCCs. Histomorphologically, CA4P induced more extensive necrosis in R1-tumors(92.6%) than in HCCs(50.2%)(P < 0.01); tumor vascularity heterogeneously scored +^+++ in HCCs but homogeneously scored ++ in *** This study suggests superior performance of CA4P in metastatic over primary liver cancers, which could guide future clinical applications of vascular-disruptingagents.

关键词： hepatocellular carcinoma combretastatin A4 phosphate rhabdomyosarcoma vascular-disrupting agent magnetic resonance imaging rats

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Transforming growth factor-β1 in invasion and metastasis in colorectal cancer

引用

World Journal of Gastroenterology 2002年第4期8卷 674-678页

作者： Bin Xiong Hong-Yin yuan Ming-bo Hu feng Zhang Zheng-Zhuan Wei Ling-Ling Gong Guo-Liang Yang Department of Oncology,Affiliated Zhongnan Hospital of Wuhan University,Wuhan 430071,Hubei Province,China Bin Xiong Hong-Yin Yuan Ming-Bo Hu Feng Zhang Zheng-Zhuan Wei Ling-Ling Gong Guo-Liang Yang Department of Oncology Affiliated Zhongnan Hospital of Wuhan University Wuhan 430071 Hubei Province China

AIM：To investigate the role of TGFβ1 in invasion and metastasis in colorectal cancer by analysing TGFβ1 correlated wity depth of tumor invasion,stage and ***:Serum TGFβ1levels were determined in50patients with colorectal cancer and 30healthy volunteers using a TGFβ1 enzyme-linked immunosorbent ***β1 expression in primary and lymph node metastatic lesions were detected in 98cases of colorectal cancer by immunohistochemical staining and in situ ***:Serum levels of TGFβ1 in patients with colorectal cancer(40±18μg·L^-1)were significantly higher than those in the healthy control group(19±8μg·L^-1),P<*** levels of serum TGFβ1were found in 60%of patients with colorectal cancer when the mean+2s was used as the upper limit of the normal range(35.1μg·L^-1).Increases in serum TGFβ1 levels were significantly asociated with Dukei's stage(P<0.05),but there was no significant difference between,Duki's stage Bpatients and Dukei's stage *** the cytoplasm of cancer cells,TGFβ1 was immunostained in37.8%(37/98)of colorectal cancer,and this expression was confirmed by in situ hybridization,Among35cases of colorectal cancer with lymph node metastatic lesions,TGFβ1 positive staining was found in18(51.4%)cases of primary tumor,and 25(71.4%)cases with lymph node metastatic lesions,respectively,Of17cases with no staining in the primary lesion.7(41.2%)casesshowed TGFβ1 staining in the metastatic *** TGFβ1 levels and TGFβ1 expression in colorectal cancer tissues were correlated significantly with depth of tumor invasion,stage and metastasis,Patients in stage C-D,T3-T4and with metastasis had significantly higher TGFβ1 levels than patients in stage A-B,T1-T2and without metastasis(P<0.05).CONCLUSION:These results suggest that transforming growth factor-β1 is closely related to the invasion and metastasis of colorectal *** increased the invasive and metastatic potential of tumor by altering a tumor ***β1 ma

关键词：结直肠癌转化生长因子β1 肿瘤侵袭肿瘤转移作用机制

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effect of fixing distal radius fracture with volar locking palmar plates while preserving pronator quadratus

引用

Chinese Medical Journal 2014年第16期127卷 2929-2933页

作者： Fan Jian Chen Kai Zhu Hui Jiang bo yuan feng Zhu Xiaozhong Mei Jiong Yu Guangrong Department of Orthopedics Tongji Hospital Tongji UniversityShanghai 200065 China

Background L-shaped incision of pronator quadratus （PQ） muscle along its radial and distal borders was always taken for distal radius fractures reduction and internal *** of the PQ muscle was always recommended at the end of operation for some instructive *** repair of PQ is not satisfied because of poor quality of muscle and fascial tissues which may cause pain or impede forearm pronation and supination for post-operative scarring around *** the locking palmar plate to pass under the pronator quadratus muscle and the locking screws are inserted through miniincisions in pronator quadratus in some patients with distal radius fractures is a reasonable technique which can preserve the pronator *** purpose of this study was to evaluate and compare the clinical effects after volar plating of the distal radius fractures while preserving the pronator quadratus and pronator quadratus *** Between September 2010 and April 2012,65 patients （42 males and 23 females; aged 20-68 years and a mean age of 42.5 years） with distal radius fracture underwent open reduction and internal fixation using the volar locking palmar plates （Depuy or Smith companies）.The patients were classified as 23A-2 through 23C-3 according to the Orthopaedic Trauma Association （OTA） *** surgeries were completed by the same trained *** volar locking palmar plates of distal radius performed with preserving pronator quadratus group involved 30 patients including 19 males and 11 females and performed with pronator quadratus repair group involved 35 patients including 23 males and 12 *** compared the two groups for wrist pain,forearm range of motion,grip strength,pedoperative complications and wrist functional recovery *** The minimum follow-up for the whole cohort was one *** differences between the two groups were significant with regard to wrist pain,forearm range of motion,grip strength and wrist function at 1,2,and

关键词： distal radius fracture open reduction palmar plate pronator quadratus

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Sky location of massive black hole binaries in the foreground of Galactic white dwarf binaries

引用

Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 97-108页

作者： Pan Guo Hong-bo Jin Cong-feng Qiao Yue-Liang Wu The International Centre for Theoretical Physics Asia-Pacific University of Chinese Academy of Sciences The School of Physical Sciences University of Chinese Academy of Sciences Institute for Frontiers in Astronomy and Astrophysics Beijing Normal University National Astronomical Observatories Chinese Academy of Sciences Institute of Theoretical Physics Chinese Academy of Sciences

For space-based gravitational wave （GW） detection,the main noise source for massive black hole binaries （MBHBs） is attributed to approximately 10～7double white dwarf binaries in the *** a GW source,the amplitude of the detector response,recorded by a space-based gravitational wave detector,exhibits a modulation effect with a year period when observing the source from various orbital *** the adverse conditions mentioned above,where there is a strong foreground noise and annual modulation in the signals,we employed the wavelet transform and the strong-amplitude relevant orbital position search methods,which allows the weak MBHB sources to achieve higher locating *** detail,for two MBHB sources of lower intensity,the precision of luminosity distance,represented by the ratio ?DL/DLat the 95%confidence level,is enhanced by factors of ～*** angular resolutions,denoted by??s,are enhanced by a factor of ～*** improvements increase the number of detectable GW sources,facilitate multi-messenger follow-up observations and provide constraints on the cosmological constant.

关键词： space-based gravitational wave detection gravitational waves massive black hole binaries

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Differential diagnosis of gallstones by using hypericin as a fluorescent optical imaging agent

引用

World Journal of Gastroenterology 2016年第29期22卷 6690-6705页

作者： Marlein Miranda Cona Ye-Wei Liu Antoine Hubert Ting Yin yuan-bo feng Peter de Witte Etienne Waelkens Yan-Sheng Jiang Jian Zhang Stefaan Mulier Qian Xia Gang Huang Raymond Oyen Yi-Cheng Ni Department of Imaging and Pathology Faculty of Medicine Biomedical Sciences Group University HospitalsKU Leuven Department of Cellular and Molecular Medicine Biomedical Sciences GroupKU Leuven Molecular Biodiscovery Laboratory Faculty of Pharmaceutical Sciences Biomedical Sciences GroupKU Leuven Laboratory of Translational Medicine Jiangsu Province Academy of Traditional Chinese Medicine Department of Nuclear Medicine Ren Ji Hospital School of Medicine Shanghai Jiao Tong University

AIM: To explore the feasibility of using hypericin as an optical imaging probe with affinity for cholesterol for differential fluorescent detection of human ***: Cholesterol, mixed and pigment stones from cholecystectomy patients were incubated with hypericin or solvent. After 72 h, the stones were analysed for fluorescence(365 nm) and treated with 2-propanol/dimethyl sulfoxide for high performance liquid chromatography(HPLC) analysis. Rats with virtual gallbladder containing human cholesterol, mixed or pigment gallstones(VGHG) received 5 mg/kg hypericin or solvent and VGHG rats with cholesterol stones were given different hypericin doses(5-15 mg/kg). Twelve hours later, the stones were analysed at 365 nm. Biliary excretion and metabolites of hypericin were assessed in common bile duct(CBD) cannulated rats for 9 h using fluorospectrometry, HPLC and matrixassisted laser desorption/ionization-time-of-flight mass spectrometry(MALDI-TOF MS).RESULTS: Homogeneous high fluorescence was seen on cholesterol stones either pre-incubated with hypericin or extracted from VGHG rats receiving hypericin. Mixed stones showed a dotted fluorescent pattern, whereas pigment and solvent-treated ones lacked fluorescence. HPLC showed 7.68, 6.65 and 0.08 × 10^(-3) M of cholesterol in extracts from cholesterol, mixed, and pigment gallstones, respectively. Hypericin accounted for 2.0, 0.5 and 0.2 × 10-6 M in that order. On cholesterol stones from VGHG rats receiving different hypericin doses, a positive correlation was observed between dose and fluorescence. In the bile from CBD-cannulated rats, fluorescence represented 20% of the injected dose with two peaks in 9 h. HPLC analysis revealed that hypericin conjugates reached 60% of the peak area. By MALDI-TOF MS, hypericinglucuronide was detected. CONCLUSION: This study proves the potential use of hypericin for differential fluorescent detection of human gallstones regarding their chemical composition.

关键词： Differential detection Fluorescence Human gallstones Hypericin Rat model of cholelithiasis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

FK506 contributes to peripheral nerve regeneration by inhibiting neuroinflammatory responses and promoting neuron survival

引用

Neural Regeneration Research 2025年第7期20卷 2108-2115页

作者： Yuhui Kou Zongxue Jin Yusong yuan bo Ma Wenyong Xie Na Han Department of Trauma and Orthopedics Peking University People’s HospitalBeijingChina National Center for Trauma Medicine Peking University People’s HospitalBeijingChina Key Laboratory of Trauma and Neural Regeneration(Peking University) Ministry of EducationBeijingChina Trauma Medicine Center Peking University People’s HospitalBeijingChina Department of Orthopedics China-Japan Friendship HospitalBeijingChina

FK506(Tacrolimus)is a systemic immunosuppressant approved by the *** and Drug ***506 has been shown to promote peripheral nerve regeneration,however,its precise mechanism of action and its pathways remain *** this study,we established a rat model of sciatic nerve injury and found that FK506 improved the morphology of the injured sciatic nerve,increased the numbers of motor and sensory neurons,reduced inflammatory responses,markedly improved the conduction function of the injured nerve,and promoted motor function *** findings suggest that FK506 promotes peripheral nerve structure recovery and functional regeneration by reducing the intensity of inflammation after neuronal injury and increasing the number of surviving neurons.

关键词： FK506 inflammation motor neurons nerve regeneration neuron peripheral nerve injury sensory neurons

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Cross Attention Transformer-Mixed Feedback Video Recommendation Algorithm Based on DIEN

引用

Computers, Materials & Continua 2025年第1期82卷 977-996页

作者： Jianwei Zhang Zhishang Zhao Zengyu Cai yuan feng Liang Zhu Yahui Sun College of Software Engineering Zhengzhou University of Light IndustryZhengzhou450000China Faculty of Information Engineering Xuchang Vocational Technical CollegeXuchang461000China College of Computer Science and Technology Zhengzhou University of Light IndustryZhengzhou450000China College of Electronics and Information Zhengzhou University of Light IndustryZhengzhou450000China

The rapid development of short video platforms poses new challenges for traditional recommendation *** systems typically depend on two types of user behavior feedback to construct user interest profiles:explicit feedback(interactive behavior),which significantly influences users’short-term interests,and implicit feedback(viewing time),which substantially affects their long-term ***,the previous model fails to distinguish between these two feedback methods,leading it to predict only the overall preferences of users based on extensive historical behavior ***,it cannot differentiate between users’long-term and shortterm interests,resulting in low accuracy in describing users’interest states and predicting the evolution of their *** paper introduces a video recommendationmodel calledCAT-MFRec(CrossAttention Transformer-Mixed Feedback Recommendation)designed to differentiate between explicit and implicit user feedback within the DIEN(Deep Interest Evolution Network)*** study emphasizes the separate learning of the two types of behavioral feedback,effectively integrating them through the cross-attention ***,it leverages the long sequence dependence capabilities of Transformer technology to accurately construct user interest profiles and predict the evolution of user *** results indicate that CAT-MF Rec significantly outperforms existing recommendation methods across various performance *** advancement offers new theoretical and practical insights for the development of video recommendations,particularly in addressing complex and dynamic user behavior patterns.

关键词： Video recommendation user interest cross-attention transformer

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：