检索结果-南通市图书馆

水生生物学报 2006年第6期30卷 680-683页

作者： WANG yuan, XIONG Li, TANG Hong-Feng, sheng Xiu-Mei, LOU An and LI Jin (College of Life Sciences, Central China Normal University, Wuhan, Hubei Province, 430079) College of Life Sciences Central China Normal University Hubei Wuhan 430079

Beta-cypermethrin is one of the synthetic pyrethroid, which is widely used to control insect pests and is found to be more effective than organphosphates and carbamates. However, it is also reported to be more toxic than organphosphates and carbamates. It has been suggested that synthetic pyrethroids are readily absorbed by the gills of fish even at very low concentrations. Glutamic-pyruvic transaminase (GPT) and glutamic-oxaloacetic transaminase (GOT) exist in the cells of every tissue, particularly in the liver. If the liver is damaged, the enzymes are discharged from the cells into the serum. It increases the GPT and GOT metabolic activities quickly. It is, therefore, proposed that the effects of toxicants on serum GPT and GOT could be used as indexes in toxicological assessments. In this experiment, the effectiveness of beta-cypermethrin on the acute toxicity and on serum GPT and GOT concentration of crucian carp was studied. The LC 50 of beta-cypermethrin for crucian carp was 11.4μg/L. The crucian carp serum was treated against beta-cypermethrin levels of 0.114μg/L, 0.57μg/L and 1.14μg/L for exposure times of 0d, 5d, 10d, 15d and 20d, at all concentrations. The results show that when the beta-cypermethrin concentration increases and the exposure time is prolonged, the GPT and GOT activities of serum increased also. The results proved that beta-cypermethrin could cause great damage to crucian carp and its biochemical functions.

关键词： Beta-cypermethrin Acute toxicity GPT GOT

在线全文

学校读者我要写书评

暂无评论

一种多普勒后处理的STAP方法研究

西安电子科技大学学报 2009年第2期36卷 240-244,255页

作者：李彩彩廖桂生朱圣棋袁晓懿西安电子科技大学雷达信号处理重点实验室陕西西安710071

针对现有多普勒后处理的空时自适应处理(STAP)方法在不加权时多普勒通道相互正交,甚至在加权时相关性也不高的问题,提出了一种新的多普勒后处理的STAP方法.通过缩小主、辅多普勒通道中心频率的间距来提高相关性,降低杂波的自由度,减轻... 详细信息

针对现有多普勒后处理的空时自适应处理(STAP)方法在不加权时多普勒通道相互正交,甚至在加权时相关性也不高的问题,提出了一种新的多普勒后处理的STAP方法.通过缩小主、辅多普勒通道中心频率的间距来提高相关性,降低杂波的自由度,减轻空域自适应处理的负担,使其性能提高.对机载双通道雷达实测数据的处理验证了该方法对杂波具有良好的抑制能力,能使3DT方法的改善因子提高0.5 dB,且在阵元幅相误差高达10%时,仍具有较高的稳健性.

关键词：空时自适应处理多普勒和/差波束杂波自由度改善因子

ENSO signals and their spatial-temporal variation characteristics recorded by the sea-level changes in the northwest Pacific margin during 1965-2005

在线全文

学校读者我要写书评

暂无评论

Science China Earth Sciences 2009年第5期52卷 869-882页

作者： yuan LinWang,YU Zhaoyuan,xie ZhiRen,SONG ZhiYao & Lü GuoNian School of Geographical Science,Nanjing Normal University,Nanjing 210046,China School of Geographical Science Nanjing Normal University Nanjing China

Sea-level is closely linked to the Earth's climate and its change is important as a metric for global and regional climate change. Identifying, extracting, and revealing such information through detailed analysis is the prerequisite for understanding the mechanisms of sea-level change. The monthlyaverage tide-change records reported and examined in this paper are from 10 tide gauge stations distributed in the northwest margin of the Pacific Ocean, registered during the period 1965-2005. In particular, we have utilized the Second Order Blind Identification (SOBI) method to identify and the Empirical Mode Decomposition (EMD) method to extract the El Nio-Southern Oscillation (ENSO) signals imprinted in those tide gauge records; and subsequently, we have investigated the spa-tial-temporal characteristics of the extracted ENSO signals using wavelet analysis methods. The following results are obtained: (1) the ENSO events recorded by each tide gauge series are of different types and intensity, which show considerable temporal-spatial variation characteristics, with sea-level responses to ENSO signals remarkably stronger in low latitude areas than in medium-high latitude areas; (2) due to the influences of ocean currents, topographical conditions, and other factors, there exist variations in the type of relationship between the sea-level changes and the recorded ENSO events at different latitudes; (3) sea-level changes can also denote scale-variation characteristics of ENSO events, and particularly, since 1980s, all the tide gauges located south of Kanmen show intense responses to ENSO and the timescale of ENSO events extended gradually from around 4 years to 2-8 years, reflecting variations in the intensity and frequency of ENSO events; and (4) reverse changes of certain scale were noted before and after strong ENSO events recorded by sea-level changes, supporting the research findings about the interaction (mutual coupling and superimposition) between the probability of

关键词： sea level change ENSO SOBI cross wavelet spectrum wavelet coherence

同方期刊数据库

Performance verification and comparison of TianLong automatic hypersensitive hepatitis B virus DNA quantification system with Roche CAP/CTM system

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2017年第37期23卷 6845-6853页

作者： Ming Li Lin Chen Li-Ming Liu Yong-Li Li Bo-An Li Bo Li yuan-Li Mao Li-Fang Xia Tong Wang Ya-Nan Liu Zheng Li Tong-sheng Guo School of Mechanical Engineering Xi'an Jiaotong University Xi'an Tian Long Science and Technology Co. Ltd. Center of Clinical Laboratory Medicine 302 Military Hospital of China Department of Laboratory Medicine Beijing Xiaotangshan Hospital

AIM To investigate and compare the analytical and clinical performance of Tian Long automatic hypersensitive hepatitis B virus(HBV) DNA quantification system and Roche CAP/CTM *** Two hundred blood samples for HBV DNA testing, HBV-DNA negative samples and high-titer HBV-DNA mixture samples were collected and prepared. National standard materials for serum HBV and a worldwide HBV DNA panel were employed for performance verification. The analytical performance, such as limit of detection, limit of quantification, accuracy, precision, reproducibility, linearity, genotype coverage and cross-contamination, was determined using the Tian Long automatic hypersensitive HBV DNA quantification system(TL system). Correlation and Bland-Altman plot analyses were carried out to compare the clinical performance of the TL system assay and the CAP/CTM system. RESULTS The detection limit of the TL system was 10 IU/m L, and its limit of quantification was 30 IU/m L. The differences between the expected and tested concentrations of the national standards were less than ± 0.4 Log10 IU/m L, which showed high accuracy of the system. Results of the precision, reproducibility and linearity tests showed that the multiple test coefficient of variation(CV) of the same sample was less than 5% for 102-106 IU/m L; and for 30-108 IU/m L, the linear correlation coefficient r2 = 0.99. The TL system detected HBV DNA(A-H) genotypes and there was no cross-contamination during the "checkerboard" test. When compared with the CAP/CTM assay, the two assays showed 100% consistency in both negative and positive sample results(15 negative samples and 185 positive samples). No statistical differences between the two assays in the HBV DNA quantification values were observed(P > 0.05). Correlation analysis indicated a significant correlation between the two assays, r2 = 0.9774. The Bland-Altman plot analysis showed that 98.9% of the positive data were within the 95% acceptable range, and the maximum di

关键词： Analytical performance Hepatitis B virus DNA quantification Clinical performance Hepatitis B virus Real-time quantification PCR

不同生物活性基团修饰的纳米磁珠在核酸提取中的效能比较

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

分子诊断与治疗杂志 2024年第4期16卷 734-738页

作者：曲业敏邵丽莹袁晓燕宋宇丛海燕国东谢龙迟翔宇王明义威海威高生物科技有限公司山东威海264200 威海市立医院中心实验室山东威海264200 卫生部医药生物工程技术研究中心临床医学分子诊断国家地方联合工程实验室广东省核酸分子诊断工程技术研究中心广东省临床医学分子诊断工程技术中心广州达安基因股份有限公司广东广州510665

目的评价不同生物活性基团修饰的纳米磁珠核酸提取效能,为临床应用及结果评价提供一些依据。方法通过不同生物活性基团修饰的纳米磁珠对检测乙型肝炎病毒的标本进行核酸提取,采用微量分光光度计(NanoDrop One~c)检测核酸的浓度及纯度,... 详细信息

目的评价不同生物活性基团修饰的纳米磁珠核酸提取效能,为临床应用及结果评价提供一些依据。方法通过不同生物活性基团修饰的纳米磁珠对检测乙型肝炎病毒的标本进行核酸提取,采用微量分光光度计(NanoDrop One~c)检测核酸的浓度及纯度,实时荧光定量聚合酶链式反应(RT-PCR)检测样本的CT值。结果在几种纳米磁珠提取法中,超顺磁性羧基纳米微粒提取的核酸浓度及纯度最高(浓度平均为953.3 IU/mL),其次是二氧化硅磁性微球与羧基微球混合纳米磁珠及纳米磁性氧化物MnFe_(2)O_(4)提取法。羟基修饰二氧化硅颗粒以及壳聚糖包覆的磁珠提取的核酸浓度较高,但纯度较差(A260/280及A260/230比值均超出标准范围)。对于同一样本,超顺磁性羧基纳米微粒提取的核酸扩增CT值为(21.28±0.36),核酸提取效率明显高于离心柱提取法,且具有统计学意义。二氧化硅磁性微球和羧基微球混合纳米磁珠、羟基修饰二氧化硅纳米磁珠及壳聚糖包覆的纳米磁珠核酸提取效率均低于离心柱提取法。此外,超顺磁性羧基纳米微粒的提取时间可缩短至15分钟。结论超顺磁性羧基纳米微粒核酸提取效率、精密度及核酸产物纯度最高,有较大的临床应用价值。

关键词：纳米磁珠实时荧光定量PCR 效能比较

Total femur replacement with 18 years of follow-up:A case report

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第15期10卷 4957-4963页

作者： Yi-Hao Yang Jia-Xiang Chen Qiu-Yun Chen Yu Wang Yao-Bin Zhou Hong-Wei Wang Tao yuan Hong-Pu Sun Lin xie Zhi-Hong Yao Zuo-Zhang Yang Department of Orthopaedics The Third Affiliated Hospital of Kunming Medical UniversityYunnan Cancer HospitalYunnan Cancer CenterKunming 650118Yunnan ProvinceChina Department of Orthopaedics The People’s Hospital of FuyuanFuyuan CountyQujing 655500Yunnan ProvinceChina Department of Medical Oncology The Third Affiliated Hospital of Kunming Medical UniversityYunnan Cancer HospitalYunnan Cancer CenterKunming 650118Yunnan ProvinceChina

BACKGROUND Osteosarcoma is one of the most common primary malignant bone tumors and is more common in *** femur is the most common site of osteosarcoma,and many patients require total femur *** reviewed the relevant literature and case findings,summarized and analyzed this case in combination with relevant literature,and in doing so improved the understanding of the *** SUMMARY The case we report was a 15-year-old patient who was admitted to the hospital 15 days after the discovery of a right thigh *** diagnosis was osteosarcoma of the right femoral *** completion of neoadjuvant chemotherapy and preoperative preparation,total right femoral resection+artificial total femoral replacement was ***,chemotherapy was continued after *** patient recovered well after treatment,and the function of the affected limb was *** recurrence,metastasis,prosthesis loosening,dislocation,fracture or other complications were found during 18 years of *** present,the patient can still work and lives *** results of the medium-and longterm follow-up were *** Artificial total femur replacement is a feasible limb salvage operation for patients with femoral malignant tumors,and the results of medium-and long-term follow-up are satisfactory.

关键词： Total femur replacement Osteosarcoma Medium and long-term follow-up Case report

Endovascular Catheter-guided Forceps Biopsy for the Diagnosis of Suspected Pulmonary Artery Sarcoma： A Preliminary Study of Eight Cases

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2016年第18期129卷 2246-2249页

作者： Wan-Mu xie Zhen-Guo Zhai Le-Feng Wang Jun Wan yuan-Hua Yang Chen Wang Department of Respiratory and Critical Care Medicine China-Japan Friendship Hospital Beijing 100029 China Beijing Key Laboratory of Respiratory and Pulmonary Circulation Disorders Beijing 100020 China Department of Cardiology Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China Department of Respiratory and Critical Care Medicine Beijing Chao-Yang Hospital Capital Medical University Beijing 100020 China

Pulmonary artery sarcoma （PAS） is a rare malignant tumor that originates from the pulmonary artery （PA） with a poor prognosis,Early diagnosis and radical surgical resection offer the only chance for survival As most PA sarcomas involve the PA trunk, making a preoperative histopathological diagnosis is quite difficult. So far, most PAS cases were reported with diagnosis made either at autopsy or intraoperatively with frozen sections.

关键词： Biopsy Histopathological Diagnosis Pulmonary Artery Sarcoma

在线全文

学校读者我要写书评

暂无评论

信号交叉口利用中央分隔带左转的优化研究

西安建筑科技大学学报（自然科学版） 2006年第6期38卷 814-818页

作者：张生瑞袁静长安大学公路学院陕西西安710064

对于有中央分隔带的交叉口,利用分隔带实现左转,可以减少交叉口的冲突点,减少其他相位上车流的延误,提高通行能力,但也相应地增加左转车流的延误.本文基于对利用中央分隔带的渠化设置的各车流延误计算,以交叉口总延误最小为目标,计算得... 详细信息

对于有中央分隔带的交叉口,利用分隔带实现左转,可以减少交叉口的冲突点,减少其他相位上车流的延误,提高通行能力,但也相应地增加左转车流的延误.本文基于对利用中央分隔带的渠化设置的各车流延误计算,以交叉口总延误最小为目标,计算得到具体的交叉口设置形式.并比较设置前后的交叉口总延误,得到渠化设置的交叉口流量条件,为交叉口利用中央分隔带实现左转的优化设计提供了理论基础.最后通过具体的交叉口应用,得到了该交叉口利用中央分隔带左转设置的具体指标和方法,计算结果也证明了该交叉口渠化设置的实用性.

关键词：交通工程信号交叉口左转远引交通延误

Adjacent segment disease following Dynesys stabilization for lumbar disorders:A case series of mid-and long-term follow-ups

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2021年第35期9卷 10850-10860页

作者： Kuan-Ju Chen Chien-Ying Lai Lu-Ting Chiu Wei-sheng Huang Pang-Hsuan Hsiao Chien-Chun Chang Cheng-Jyh Lin yuan-Shun Lo Yen-Jen Chen Hsien-Te Chen Department of Orthopedic Surgery China Medical University HospitalTaichung City 404Taiwan Spine Center China Medical University HospitalTaichung City 404Taiwan Management Office for Health Data China Medical University HospitalTaichung City 404Taiwan College of Medicine China Medical UniversityTaichung City 404Taiwan School of Chinese Medicine China Medical UniversityTaichung City 404Taiwan Department of Orthopedic Surgery China Medical University HospitalChina Medical UniversityTaichung City 404Taiwan Spine Center China Medical University HospitalChina Medical UniversityTaichung City 404Taiwan Degree Program of Biomedical Science and Engineering National Chiao Tung UniversityHsinchu City 300Taiwan Department of Biological Science and Technology National Chiao Tung UniversityHsinchu City 300Taiwan Department of Orthopedic Surgery China Medical University Beigang HospitalYunlin County 651Taiwan Graduate Institute of Precision Engineering National Chung Hsing UniversityTaichung City 404Taiwan School of Medicine China Medical UniversityTaichung City 404Taiwan Department of Sport Medicine College of Health CareChina Medical UniversityTaichung City 404Taiwan

BACKGROUND Radiologic adjacent segment degeneration(ASDeg)can occur after spinal *** segment disease(ASDis)is defined as the development of new clinical symptoms corresponding to radiographic changes adjacent to the level of previous spinal *** pre-existing ASDeg is generally considered to result in more severe ASDis;nonetheless,whether the ASDeg status before index surgery influences the postoperative risk of revision surgery due to ASDis warrants *** To identify possible risk factors for ASDis and verify the concept that greater preexisting ASDeg leads to more severe *** Data from 212 patients who underwent posterior decompression with Dynesys stabilization from January 2006 to June 2016 were retrospectively *** who underwent surgery for ASDis were categorized as group A(n=13),whereas those who did not were classified as group B(n=199).Survival analysis and Cox proportional hazards models were used to compare the modified Pfirrmann grade,University of California-Los Angeles grade,body mass index,number of Dynesys-instrumented levels,and *** The mean time of reoperation was 7.22(1.65–11.84)years in group A,and the mean follow-up period was 6.09(0.10–12.76)years in group *** significant difference in reoperation risk was observed:Modified Pfirrmann grade 3 vs 4(P=0.53)or 4 vs 5(P=0.46)for the upper adjacent disc,University of California-Los Angeles grade 2 vs 3 for the upper adjacent segment(P=0.66),age of60 years(P=0.9),body mass index25 kg/m2(P=0.3),and sex(P=0.8).CONCLUSION Greater preexisting upper ASDeg was not associated with a higher rate of reoperation for ASDis after Dynesys *** overweight tended to increase reoperation risk after Dynesys surgery for ASDis.

关键词： Adjacent segment degeneration Adjacent segment disease Degenerative lumbar spondylolisthesis Dynamic stabilization Dynesys Spinal stenosis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

多指数连续相位调制信号的早迟环定时同步

国防科技大学学报 2016年第4期38卷 113-118页

作者：谢顺钦谢滔钟声杨春王世练张健中国工程物理研究院电子工程研究所四川绵阳621000 国防科技大学电子科学与工程学院湖南长沙410073

针对多指数连续相位调制信号提出基于序列检测的早迟环定时同步,利用维特比算法的幸存度量构造定时误差估计器。根据误差估计的S曲线和方差,优化定时误差捕获范围和估计精度、消除环路假锁点,同时利用多指数连续相位调制的脉冲幅度调制... 详细信息

针对多指数连续相位调制信号提出基于序列检测的早迟环定时同步,利用维特比算法的幸存度量构造定时误差估计器。根据误差估计的S曲线和方差,优化定时误差捕获范围和估计精度、消除环路假锁点,同时利用多指数连续相位调制的脉冲幅度调制分解对定时误差估计器进行简化。仿真结果表明,优化后的早迟环定时误差捕获范围最大可达±0.5个符号周期,估计精度在中低信噪比下能够接近修正的克拉美罗界,在高信噪比下也有较好的估计性能;当早迟环定时支路的分支度量简化至最大似然序列检测的1/8时,对多进制、部分响应的多指数连续相位调制信号,造成的解调性能损失小于0.5 d B。

关键词：多指数连续相位调制定时早迟环 S曲线克拉美罗界