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Neural Regeneration Research 2013年第6期8卷 540-545页

作者： Shuju Wang Jianqiao Fang Jun ma Yanchun Wang Shaorong liang Dan Zhou Guojie Sun Department of Acupuncture and Moxibustion Third Clinical Medical CollegeZhejiang Chinese Medical University Teaching and Research Office of Acupuncture College of Acupuncture & OrthopedicsHubei University of Chinese Medicine

Acupuncture for the treatment of Parkinson＇s disease has a precise clinical outcome. This study investigated the effect of electroacupuncture at Fengfu （GV16） and Taichong （LR3） acupoints in rat models of Parkinson＇s disease induced by subcutaneous injection of rotenone into rat neck and back. Reverse transcription-PCR demonstrated that brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor mRNA expression was significantly increased in the substantia nigra of rat models of Parkinson＇s disease, and that abnormal behavior of rats was significantly improved following electroacupuncture treatment. These results indicated that electroacupuncture treatment upregulated brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor mRNA expression in the substantia nigra of rat models of Parkinson＇s disease. Thus, electroacupuncture may be useful in the treatment of Parkinson＇s disease.

关键词： neural regeneration acupuncture and moxibustion neurodegenerative diseases electroacupuncture brain-derived neurotrophic factor glial cell line-derived neurotrophic factor substantia nigra rotenone Parkinson's disease rats reverse transcription-PCR grants-supportedpaper neuroregeneration

Atomically dispersed Zn-Co-N-C catalyst boosting efficient and robust oxygen reduction catalysis in acid via stabilizing Co-N bonds

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Fundamental Research 2023年第6期3卷 909-917页

作者： Feng ma Xuan Liu Xiaoming Wang Jiashun liang Jianyu Huang Cameron Priest Jinjia Liu Shuhong Jiao Tanyuan Wang Gang Wu Yunhui Huang Qing Li State Key Laboratory of material Processing and Die&Mould Technology School of Materials Science and EngineeringHuazhong University of Science and TechnologyWuhanHubei 430074China State Key Laboratory of Refractories and Metallurgy Institute of Advanced Materials and NanotechnologyKey Laboratory of Hubei Province for Coal Conversion and New Carbon MaterialsSchool of Chemistry and Chemical EngineeringWuhan University of Science and TechnologyWuhan 430081China Clean Nano Energy Center State Key Laboratory of Metastable Materials Science and TechnologyYanshan UniversityQinhuangdao 066004China Department of Chemical and Biological Engineering University at BuffaloThe State University of New YorkBuffaloNY 14260United States State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001China National Energy Center for Coal to Clean Fuels Synfuels China Co.LtdHuairou DistrictBeijing 101400China Department of materials Science and Engineering Key Laboratory of Materials for Energy Conversion Chinese Academy of Science(CAS)University of Science and Technology of ChinaHefei 230026China Department of Chemistry and Key Laboratory for Preparation and Application of Ordered Structural materials of Guangdong Province Shantou UniversityShantou 515063China

Transition metal supported N-doped carbon(M-N-C)catalysts for oxygen reduction reaction(ORR)are viewed as the promising candidate to replace Pt-group metal(PGM)for proton exchange membrane fuel cells(PEMFCs).However,the stability of M-N-C is extremely challenging due to the demetalation,H_(2)O_(2)attack,*** the strongly oxidative conditions of *** this study,we demonstrate the universal effect of Zn on promoting the stability of atomically dispersed M-Nx/C(M=Co,Fe,Mn)catalysts and the enhancement mechanism is unveiled for the first *** best-performing dual-metal-site Zn-Co-N-C catalyst exhibits a high half-wave potential(E1/2)value of 0.81 V *** hydrogen electrode(RHE)in acid and outstanding durability with no activity decay after 15,000 accelerated degradation test(ADT)cycles at 60℃,surpassing most reported Co-based PGM-free catalysts in acid *** comparison,the Co-N-C in the absence of Zn suffers from a rapid degradation after ADT due to the demetalation and higher H_(2)O_(2)yield.X-ray adsorption spectroscopy(XAS)and density functional theory(DFT)calculations suggest the more negative formation energy(by 1.2 eV)and increased charge transfer of Zn-Co dual-site structure compared to Co-N-C could strength the Co-N bonds against the demetalation and the optimized d-band center accounts for the improved ORR kinetics.

关键词： Electrocatalysis Oxygen reduction reaction Non-noble metal catalysts Metal-nitrogen carbon catalysts Demetalation Structural stability

基于显著轮廓特征的SAR图像轮廓匹配新方法

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电子与信息学报 2021年第11期43卷 3174-3184页

作者：马晓蕊郑昌文梁毅中国科学院大学北京100049 中国科学院软件研究所北京100190 中国科学院自动化研究所北京100190 西安电子科技大学西安710071

在以星载SAR图像作为基准图、机载/弹载SAR图像作为实时图的匹配导航和精确制导研究中,传统基于点特征的匹配方法存在特征点数目过多,误匹配率较高,容易受噪声及灰度变化影响等问题。该文提出一种基于显著轮廓特征的SAR图像“由粗到精... 详细信息

在以星载SAR图像作为基准图、机载/弹载SAR图像作为实时图的匹配导航和精确制导研究中,传统基于点特征的匹配方法存在特征点数目过多,误匹配率较高,容易受噪声及灰度变化影响等问题。该文提出一种基于显著轮廓特征的SAR图像“由粗到精”的匹配新方法。该方法在对SAR图像进行预处理的基础上,采用改进的模糊C均值聚类(FCM)的图像分割方法来提取闭合轮廓特征;采用归一化轮廓中心距离描述符进行双向匹配,获得强鲁棒性的粗匹配轮廓对;在粗匹配轮廓上采用改进的局部二值模式(LBP)算子得到精匹配结果。试验结果表明,该方法在图像旋转、空间变化以及噪声干扰较大的情况下,具有精确性高、鲁棒性强的优势,适宜遥感SAR图像匹配。

关键词：合成孔径雷达图像轮廓匹配质心距离局部二值模式

Total endoscopic nephroureterectomy for native kidney ipsilateral to transplanted kidney

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Chinese Medical Journal 2012年第21期125卷 3827-3830页

作者： HOU Xiao-fei BI Hai ma Lu-lin ZHAO Lei WANG Guo-liang Department of Urology Peking University Third Hospital49 North Garden RoadHaidian DistrictBeijing 100191China

Background From limited exposure with management of the native distal ureter ipsilateral to the transplanted kidney, we usually choose open nephroureterectomy （NU） or laparoscopic NU combined with an open approach in renal transplant （RTx） recipients. We herein describe our preliminary experience with total endoscopic NU with bladder cuff （BC） excision and evaluate its feasibility for RTx recipients.

关键词： kidney transplantation " urinary tract " urothelial carcinoma " nephroureterectomy " endoscopic surgery

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药物释放系统

化工学报 2005年第6期56卷 955-961页

作者：刘袖洞马小军袁权中国科学院大连化学物理研究所辽宁大连116023

介绍了口服、透皮、黏膜等非注射给药途径药物释放系统的研究进展,以及靶向、细胞微囊化和微加工等新技术手段在药物释放系统中的应用,评述了药物释放系统的问题及解决手段.

关键词：药物释放系统靶向细胞微囊化微加工

Diffusion-weighted magnetic resonance imaging in diagnosis of Creutzfeldt-Jakob disease

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Chinese Medical Journal 2006年第15期119卷 1242-1247页

作者： LOU Xin ma Lin AN Ning-yu CAI You-quan liang Yan GUO Xing-gao Department of Radiology PLA General Hospital Beijing 100853 China

Background Creutzfeldt-Jakob disease （CJD）, a rare disease, is uncharacterized by computed tomography （CT） and magnetic resonance imaging （MRI）. This study was aimed to evaluate the diffusion-weighted MRI （DWI） manifestations of CJD and to discuss their diagnostic value. Methods The findings of T1-weighted MR/（T1WI）, T2-weighted MRI（T2WI）, DWI and post-contrast MRI in 5 patients （3 patients with biopsy-proven CJD and 2 patients with clinically-proven CJD） were retrospectively analyzed in this study. Results Four out of the 5 patients had cerebral atrophy of various degrees. One patient showed symmetric high signal intensity at the bilateral globus pallidus and the head of the caudate nucleus, with very high signal in the cerebral cortex on the DWI. This patient only had symmetric slightly high signal at the bilateral globus pallidus and putamen on T2WI. One patient had high signal intensity at the basal ganglia and cerebral cortex on DWI, but abnormal T2 signal intensity at the bilateral paraventricular white matter on MRI. Two patients presented with widely gyri-like high signal intensity at the cortex on DWI, but routine MRI showed bilateral paraventricular long T2 signal intensity in 1 patient and no abnormal findings in another. No abnormalities were shown by both routine MRIand DWI in the last patient. Conclusions DWI is more sensitive than its conventional counterpart in the depiction of CJD. DWI is more sensitive to detect cortical abnormal signal intensity in CJD not detected by T2WI.

关键词： brain diseases Creutzfeldt-Jakob disease magnetic resonance imaging diffusion

Prevalence and correlates of meeting the muscle-strengthening exercise recommendations among Chinese children and adolescents:Results from 2019 Physical Activity and Fitness in China—The Youth Study

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Journal of Sport and Health Science 2022年第3期11卷 358-366页

作者： Fei Xin Zheng Zhu Sitong Chen Huan Chen Xiaoqing Hu Xiao ma Kun liang Yang Liu Lijuan Wang Yujun Cai Ang Chen Yan Tang School of Physical Education and Sport Training Shanghai University of SportShanghai 200438China Shanghai Research Centre for Physical Fitness and Health of Children and Adolescents Shanghai University of SportShanghai 200438China School of Kinesiology Shanghai University of SportShanghai 200438China Institute for Health and Sport Victoria UniversityMelbourneVIC 3000Australia Institute of Sport Sciences Shanghai University of SportShanghai 200438China Department of Kinesiology University of North Carolina at GreensboroGreensboroNC 27402USA

Purpose This study aimed to describe the national prevalence of Chinese children and adolescents who met the World Health Organization muscle-strengthening exercise(MSE)recommendations and identify correlates of meeting the MSE *** Cross-sectional data from the 2019 Physical Activity and Fitness in China—The Youth Study,a nationally representative sample of Chinese children and adolescents(n=80,413;mean age=13.7 years;53.9%girls)and their parents,were *** and adolescents who reported engaging≥3 days(up to 7 days)of MSE per week were classified as meeting the MSE ***,demographics,lifestyle behaviors(sport participation,moderate-to-vigorous physical activity,screen time,and sleep duration),exercise intention,peer and parental support,and parental MSE participation were assessed through *** regression models were used to determine the correlates of meeting the MSE *** analyses were completed in *** Overall,39.3%of children and adolescents met the MSE ***,10th-12th graders,minorities,those from lower income households and those from families with lower parental education were less likely to meet the MSE *** and adolescents who were proficient in≥2 sports were more likely to meet the MSE recommendations(adjusted odds ratio(aOR)=1.44,95%confidence interval(95%CI):1.26-1.65),as were those with more moderate-to-vigorous physical activity(aOR=1.57,95%CI:1.53-1.61).Additionally,children and adolescents with high exercise intention(aOR=1.60,95%CI:1.51-1.69),those whose parents met the adult MSE recommendations(aOR=1.46,95%CI:1.40-1.52),and those who received high peer(aOR=1.27,95%CI:1.20-1.34)and parental support(aOR=1.07,95%CI:1.04-1.12)were more likely to meet the MSE *** Less than two-fifths of Chinese children and adolescents met the World Health Organization MSE *** correlates identified in our study can

关键词： Exercise China Youth Study Health Population-based School-aged children Strength training

地表水-地下水相互作用下NH4-N的吸附/解吸行为及其对N迁移转化的影响

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地球科学 2024年第10期49卷 3761-3772页

作者：张安广梁莹马瑞中国地质大学环境学院湖北武汉430078

铵吸附/解吸是控制氮转化的重要反应之一,但其在地表水-地下水相互作用影响下对氮迁移转化的影响机制尚不清晰.以江汉平原东部沙湖监测场为研究区,通过分析地下水位及其水化学指标长期监测数据,结合室内土柱实验和反应迁移数值模型解译... 详细信息

铵吸附/解吸是控制氮转化的重要反应之一,但其在地表水-地下水相互作用影响下对氮迁移转化的影响机制尚不清晰.以江汉平原东部沙湖监测场为研究区,通过分析地下水位及其水化学指标长期监测数据,结合室内土柱实验和反应迁移数值模型解译,识别了地表水补给和地下水排泄两种模式下NH_(4)-N的迁移转化过程,探究了水动力驱动下N的迁移转化机制.研究表明,农业活动带来的高浓度NH_(4)-N会被表层沉积物颗粒吸附;地表水入渗会促进沉积物中NH_(4)-N的解吸附及后续的硝化作用,引起地下水中NO_(3)-N浓度上升;含NH_(4)-N的地下水排泄过程会促进沉积物对NH_(4)-N的吸附,使沉积物中NH_(4)-N吸附量升高.阳离子交换是影响NH_(4)-N迁移转化的关键机制,地表水-地下水相互作用引起的水文地球化学环境变化影响了NH_(4)-N的吸附/解吸及后续生物地球化学反应.

关键词：铵态氮离子交换反应迁移模型地表水地下水江汉平原水文地质学

氧化石墨催化醇和酚的四氢吡喃化保护与脱保护

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有机化学 2013年第9期33卷 2004-2009页

作者：徐亮杨安卫马宁天津大学理学院化学系天津300072

氧化石墨作为一种高效、低毒、易得、可重复使用的弱酸性催化剂用于醇和酚的四氢吡喃化保护与脱保护反应.反应在室温下短时间内即可完成,产物收率高,分子中的碳碳不饱和键不受影响,氧化石墨可重复使用至少4次.该方法具有操作简便、安全... 详细信息

氧化石墨作为一种高效、低毒、易得、可重复使用的弱酸性催化剂用于醇和酚的四氢吡喃化保护与脱保护反应.反应在室温下短时间内即可完成,产物收率高,分子中的碳碳不饱和键不受影响,氧化石墨可重复使用至少4次.该方法具有操作简便、安全、经济、环境友好等优点.

关键词：氧化石墨催化剂四氢吡喃化醇酚

土壤空气压力影响下的非饱和入渗格林-安姆特模型

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水利学报 2005年第6期36卷 733-736页

作者：李援农费良军西安理工大学水资源研究所

利用自制的入渗仪测定了土壤入渗过程中被禁锢的土壤空气压力大小及变化以研究禁锢土壤空气压力对非饱和土壤入渗水流的阻碍作用。通过自由入渗与恒定土壤空气压力入渗试验结果对比得出,研究入渗问题必须考虑禁锢土壤空气压力的影响作... 详细信息

利用自制的入渗仪测定了土壤入渗过程中被禁锢的土壤空气压力大小及变化以研究禁锢土壤空气压力对非饱和土壤入渗水流的阻碍作用。通过自由入渗与恒定土壤空气压力入渗试验结果对比得出,研究入渗问题必须考虑禁锢土壤空气压力的影响作用。本文利用自由入渗试验、恒定土壤空气压力入渗试验和土壤水力性能试验结果,给出了禁锢土壤空气压力影响下的格林-安姆特模型。

关键词：自由入渗恒定土壤空气压力入渗禁锢土壤空气压力格林-安姆特模型