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聚焦脉冲激光作用下Ge_2Sb_2Te_5薄膜晶化过程及机理

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无机材料学报 2002年第6期17卷 1245-1252页

作者：魏劲松阮昊干福熹中国科学院上海光学精密机械研究所上海201800

采用聚焦脉冲激光研究了Ge2Sb2Te5薄膜在沉积和激光淬火两种非晶态下反射率与激光脉冲宽度变化的关系,发现沉积态的Ge2Sb2Te5薄膜在晶化触发阶段内的反射率随激光脉冲宽度增加而减小,经过激光淬火的非晶态Ge2Sb2Te5薄膜在晶化触发阶段... 详细信息

采用聚焦脉冲激光研究了Ge2Sb2Te5薄膜在沉积和激光淬火两种非晶态下反射率与激光脉冲宽度变化的关系,发现沉积态的Ge2Sb2Te5薄膜在晶化触发阶段内的反射率随激光脉冲宽度增加而减小,经过激光淬火的非晶态Ge2Sb2Te5薄膜在晶化触发阶段内的反射率随激光脉冲宽度增加而变化平缓.本文借用气-液体系中过饱和度分析液滴形成的原理,从统计物理学角度详细研究了两种非晶态Ge2Sb2Te5薄膜在脉冲激光作用下的晶化过程及机理,结果表明,当Ge2Sb2Te5的非晶态程度处于未饱和或饱和状态时不形成晶核;当Ge2Sb2Te5的非晶态程度处于过饱和状态时,此时的Ge2Sb2Te5为亚稳态,可能形成大小不等的晶核,但只有半径大于临界晶核尺寸时才可能长大成晶粒.而应力降低晶化能垒,增加非晶态Ge2Sb2Te5的过饱和度是导致沉积态与激光淬火态的Ge2Sb2Te5薄膜在晶化触发阶段内反射率随激光脉冲宽度变化规律不一致的根本原因,并据此解释了Ge2Sb2Te5薄膜在这两种状态下的反射率随激光脉冲宽度的变化特点及规律.

关键词：聚焦脉冲激光晶化过程 Ge2Sb2Te5薄膜过饱和度晶化机理相变光储存

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浅析Excel在现代会计中的运用

科技情报开发与经济 2005年第8期15卷 134-135页

作者：郝源富西曲矿选煤厂财务科山西古交030200

介绍了Excel中文电子表格处理软件在现代会计工作中的应用,包括会计报表的编制,财务分析的编制,记账凭证的检索,重点往来款项明细表的编制等。

关键词： Excel 电子表格处理软件会计报表财务分析

Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： haonan Zhang Cheng hao Tongtong fu Dian Yu Jane Howe Kaiwen Chen Ning Yan hao Ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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近场光存储及其研究进展

物理学进展 2002年第2期22卷 188-197页

作者：魏劲松张约品阮昊干福熹中国科学院上海光学精密机械研究所上海201800

本文从近场光学的超分辨原理出发详细介绍和分析了孔径探针型近场光存储技术、SIL透镜近场光存储技术和近场超分辨结构光盘存储技术等的基本原理。

关键词： SIL透镜 Supr-RENS 光存储近场光学光盘存储信息存储超分辨原理

High-dose dexamethasone regulates microglial polarization via the GR/JAK1/STAT3 signaling pathway after traumatic brain injury

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Neural Regeneration Research 2025年第9期20卷 2611-2623页

作者： Mengshi Yang Miao Bai yuan Zhuang Shenghua Lu Qianqian Ge hao Li Yu Deng Hongbin Wu Xiaojian Xu Fei Niu Xinlong Dong Bin Zhang Baiyun Liu Beijing Tiantan Hospital Capital Medical UniversityBeijingChina Department of Neurology The First Hospital of Tsinghua UniversityBeijingChina Department of Neurotrauma and Beijing Key Laboratory of Central Nervous System Injury Beijing Neurosurgical InstituteCapital Medical UniversityBeijingChina Department of Critical Care Medicine Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Center for Nerve Injury and Repair Beijing Institute of Brain DisordersChina National Clinical Research Center for Neurological DiseasesBeijingChina

Although microglial polarization and neuroinflammation are crucial cellular responses after traumatic brain injury,the fundamental regulatory and functional mechanisms remain insufficiently *** potent anti-inflammato ry agents,the use of glucoco rticoids in traumatic brain injury is still controversial,and their regulatory effects on microglial polarization are not yet *** the present study,we sought to determine whether exacerbation of traumatic brain injury caused by high-dose dexamethasone is related to its regulatory effects on microglial polarization and its mechanisms of *** vitro cultured BV2 cells and primary microglia and a controlled cortical impact mouse model were used to investigate the effects of dexamethasone on microglial ***,dexamethasone,RU486(a glucocorticoid receptor antagonist),and ruxolitinib(a Janus kinase 1 antagonist)were ***-sequencing data obtained from a C57BL/6 mouse model of traumatic brain injury were used to identify potential targets of *** Morris water maze,quantitative reverse transcription-polymerase chain reaction,western blotting,immunofluorescence and confocal microscopy analysis,and TUNEL,Nissl,and Golgi staining were performed to investigate our ***-throughput sequencing results showed that arginase 1,a marker of M2 microglia,was significantly downregulated in the dexamethasone group compared with the traumatic brain injury group at3 days post-traumatic brain *** dexamethasone inhibited M1 and M2 microglia,with a more pronounced inhibitory effect on M2microglia in vitro and in *** receptor plays an indispensable role in microglial polarization after dexamethasone treatment following traumatic brain ***,glucocorticoid receptor activation increased the number of apoptotic cells and neuronal death,and also decreased the density of dendritic spines.A possible downstream receptor signaling mechanism is th

关键词： apoptosis BV2 microglia dexamethasone glucocorticoid receptor glucocorticoids innate immune system microglial polarization neuroinflammation primary microglia traumatic brain injury

Microstructural evolution of fine-grained ZA27 alloy during partial remelting

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China Foundry 2010年第4期7卷 331-336页

作者： Chen Tijun fu Mingfeng hao yuan Key Laboratory of Gansu Advanced Nonferrous Materials Lanzhou University of Technology Lanzhou 730050 China

The microstructural evolution process of fined-grained ZA27 alloy during partial remelting has been investigated. The relationship between the as-cast and semi-solid microstructures has been discussed in particular. The results indicate that a semi-solid microstructure with small and spheroidal primary particles can be obtained when the ZA27 alloy is partially remelted. The microstructural evolution can be divided into four stages, the initial coarsening of the dendrites due to coalescence of dendrite arms, structural separation resulted from the melting of residual interdendritic eutectic, spheroidization due to the partial melting of solid particles and final coarsening attributed to the coalescence and Ostwald ripening. An equiaxed dendrite in the as-cast microstructure may evolve into one spheroidal particle in the semi-solid microsturucture after being partially remelted. The more equiaxed the dendrites in an as-cast microstructure are, the more spheroidal the solid particles in the semi-solid microstructure will be. Finer primary particles could be obtained if the alloy with finer as-cast microstructure was partially remelted. However, due to the coalescence effect, their sizes cannot be reduced further if the refined as-cast microstructure reached a certain extent.

关键词： ZA27 alloy thixoforming semi-solid microstructure partial remelting

Portal vein gas combined with pneumatosis intestinalis and emphysematous cystitis:A case report and literature review

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World Journal of Clinical Cases 2022年第25期10卷 8945-8953页

作者： Shi-fu Hu Han-Bo Liu yuan-yuan hao Department of General Surgery Tianjin Xiqing HospitalTianjin 300100China Department of Geriatrics Tianjin Xiqing HospitalTianjin 300100China

BACKGROUND Portal venous gas(PVG)is a rare clinical condition usually indicative of severe disorders,including necrotizing enterocolitis,bowel ischemia,or bowel wall rupture/*** intestinalis(PI)is a rare illness characterized by an infiltration of gas into the intestinal *** cystitis(EC)is relatively rare and characterized by intramural and/or intraluminal bladder gas best depicted by cross-sectional *** study reports a rare case coexistence of PVG presenting with PI and *** SUMMARY An 86-year-old woman was admitted to the emergency room due to the progressive aggravation of pain because of abdominal fullness and distention,complicated with vomiting and stopping defecation for 4 *** abdominal computed tomography(CT)plain scan indicated intestinal obstruction with ischemia changes,gas in the portal vein,left renal artery,superior mesenteric artery,superior mesenteric vein,some branch vessels,and bladder pneumatosis with air-fluid *** surgery was conducted on the *** necrosis was found in the small intestine approximately 110 cm below the Treitz ligament and in the ileocecal junction and ascending colon *** included excision of the necrotic small intestine and right colon,fistulation of the proximal small intestine,and distal closure of the transverse ***,the patient displayed postoperative short bowel syndrome but had a good *** received intravenous fluid infusion and enteral nutrition maintenance every other day after discharge from the community *** Emergency surgery should be performed when CT shows signs of PVG with PI and EC along with a clinical situation strongly suggestive of bowel ischemia.

关键词： Portal vein gas Mesenteric ischemia Pneumatosis intestinalis Emphysematous cystitis Bowel necrosis Case report

Strategies for Precise Engineering and Conjugation of Antibody Targeted-nanoparticles for Cancer Therapy

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Current Medical Science 2020年第3期40卷 463-473页

作者： yuan-yuan GUO Lu HUANG Zhi-ping ZHANG De-hao fu Department of Pharmacy Liyuan HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430077China School of Pharmacy Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Orthopaedics Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China

Improvements in the diagnosis and treatment of cancer are urgently needed for use in ***(NPs)can reduce the side effects of traditional chemotherapy by sustained release of loaded drugs and increase therapeutic *** can also enhance endothelial permeation retention by size effect and its accumulation in tumor cells through passive ***,it is critical to treat cancer with a controlled targeted drug which can be specifically delivered into tumor cells and released there,resulting in a targeted therapy to eradicate tumor cells while sparing normal *** this end,antibody-mediated targeting therapy has been developed,but imperfections in antibodies(Abs)limit this ***,the combination of NPs and Abs has been highly valued in recent years,because conjugating special Abs on the surface of NPs can increase targeting efficiency,enabling selective delivery of anti-cancer drugs to tumor *** this mini-review,we would like to enumerate the strategies for the conjugation of Abs to the surface of the NPs as well as the precise engineering of targeted *** application of targeting antibody fragments in this drug delivery system will also be discussed.

关键词： cancer drug delivery nanoparticle antibody conjugation

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草鱼致病性维氏气单胞菌的分离鉴定

水产科技情报 2019年第3期46卷 150-153页

作者：覃华斌袁富豪杨映谭淑雯于辉柯文杰陈言峰佛山科学技术学院生命科学与工程学院广东佛山528231

为了探索养殖生产中草鱼维氏气单胞菌病的防治方法,从广东省清远市某水产养殖场濒死的草鱼(Ctenopharyngodon idellus)体内分离到1株致病菌20160426,通过生理生化特征初步鉴定和16S r DNA序列分析,确定该菌株为维氏气单胞菌(Aeromonas v... 详细信息

为了探索养殖生产中草鱼维氏气单胞菌病的防治方法,从广东省清远市某水产养殖场濒死的草鱼(Ctenopharyngodon idellus)体内分离到1株致病菌20160426,通过生理生化特征初步鉴定和16S r DNA序列分析,确定该菌株为维氏气单胞菌(Aeromonas veronii)。人工感染试验和药敏分析的结果表明,该菌株对草鱼的半数致死量LD50为4. 87×105cfu/g,且该菌株对头孢噻肟、头孢西丁、氨曲南、头孢呋辛、头孢哌酮、头孢吡肟等药物高度敏感,在草鱼养殖生产中可选择这些药物防治该疾病。

关键词：草鱼维氏气单胞菌分离鉴定药敏试验