检索结果-南通市图书馆

Molecular Biological Mechanisms of yuan zhi Powder in the Treatment of Alzheimer's Disease: an Analysis Based on Network Pharmacology

作者： JIANG Xiao-yan ZHANG Ji-long ZOU Wei Chang zhi-yuan

U/U of the environmental sample can indicate the existence of uranium irradiation,and even can be uesd to estimate the burnup of nuclear spent fuel.A study on the burnup estimation of irradiated uranium which was mixed with natural uranium was carried out by measuring the U/U and U/U in the samples by using MC-ICP-MS. According to the equation(1) and(2),a programme for calculating the burnup of the irradiated

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

Digital Chinese Medicine 2018年第1期1卷 90-101页

作者： Wei-Jie QIANG Ying CHEN Fu-yuan HE Mei-Feng XIAO Wei-Yan CAI Yi-Fei DAI Qing YANG Yu-Jie LI Xiao-Gang WENG Qi LI Ya-Jie WANG Xiao-Xin ZHU Institute of Chinese Materia Medica China Academy of Chinese Medical SciencesBeijing 100700China Anhui University of Chinese Medicine HefeiAnhui 230012China College of Pharmacy Hunan University of Traditional Chinese MedicineChangshaHunan 410208China

Objective To predict the main active ingredients,potential targets and molecular mechanisms of yuan zhi powder in treatment of dementia by using network *** A database of chemical constituents of yuan zhi powder was constructed by using databases and *** targets were predicted by reverse molecular docking,and then a component-target network was *** target network of Alzheimer's disease(AD)was mapped and analyzed to obtain the“active ingredient-AD target”*** key targets were screened through network ***,the rationality of the prediction was analyzed by comparing with the target reported in the *** There were180chemical constituents acting on the AD target,and the targets included three key targets(cyclooxygenase-2,muscarinic acetylcholine receptor M1,and muscarinic acetylcholine receptor M2)and an important target(acetylcholine esterase).Alzheimer's disease may be treated by regulating the activity of acetylcholine receptors and the binding toβ-amyloid protein,and its biological process may be concentrated in the acetylcholine receptor signal pathway,negative regulation of synaptic transmission and so *** The fact that yuan zhi powder can treat AD is consistent with the characteristics of multi-components-multitargets-multiple pathways of traditional Chinese *** important targets obtained from network analysis have a large proportion in literature research,so network analysis have some rationality.

关键词： yuan zhi powder Network pharmacology Active ingredients–AD targets network Network analysis Dementia

Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： Xiu-Ying Chen Fa Shen Chang Cheng Yu-Han Wang Wen-Chao Cheng De-zhi yuan Wen Huang Department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China Department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

新质人才需求背景下学校教育供给变革研究

教学与管理 2025年第1期 15-18页

作者：孟志远李永梅曲阜师范大学教育学院山东曲阜273165

新质生产力的蓬勃发展呼唤新质人才并为其培养提供了重要的时域与场域,面向新质人才需求的学校教育供给变革成为教育的基础性命题。当前面向新质人才需求的学校供给变革存在“传统型”供给主体与“新质型”主体需求、“标准化”供给内... 详细信息

新质生产力的蓬勃发展呼唤新质人才并为其培养提供了重要的时域与场域,面向新质人才需求的学校教育供给变革成为教育的基础性命题。当前面向新质人才需求的学校供给变革存在“传统型”供给主体与“新质型”主体需求、“标准化”供给内容与“个性化”内容需求、“统一性”供给方式与“数智化”方式需求之间的矛盾。鉴于此,提出面向新质人才需求的学校教育供给遵循从“人类教师主体”到“人机智能联合主体”、从“统一与他主内容”到“开放与自主内容”、从“前置性预设方式”到“发展性按需方式”的变革理路,以期为学校教育供给变革与新质人才培养提供一定的理论借鉴和实践启示。

关键词：学校教育供给变革新质人才需求新质生产力新质人才培养

Nanophotonics in China： Overviews and highlights

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of physics 2012年第6期7卷 601-631页

作者： zhi-yuan Li Laboratory of Optical Physics Institute of PhysicsChinese Academy of SciencesP.O.Box 603Beijing 100190China

The major purpose of this paper is to present a brief overview of the history and the current status of nanophotonics research in China, and to highlight some research results in the past years made by the Chinese nanophotonics communities. I will first briefly introduce the principles of nanophotonics and several of its major disciplines including photonic crystals, plasmonics and metamaterials, and related artificial acoustic structures. Then I will highlight some major progresses made by Chinese research groups in these areas with the selection made merely based on my personal taste. The aim is to let these results better known and appreciated by researchers in the Chinese communities of nanophotonics and related areas, and provide better opportunities of researchers in different areas to have more communications. I also hope that this brief introduction will help to make a better bridge to connect Chinese nanophotonics communities with the broader communities in the world.

关键词： nanophotonics photonic crystals plasmonics metamaterials phononic crystals

Atom interferometers with weak-measurement path detectors and their quantum mechanical analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics B 2019年第6期28卷 45-65页

作者： zhi-yuan Li College of Physics and Optoelectronics South China University of TechnologyGuangzhou 510641China

According to the orthodox interpretation of quantum physics, wave-particle duality(WPD) is the intrinsic property of all massive microscopic particles. All gedanken or realistic experiments based on atom interferometers(AI) have so far upheld the principle of WPD, either by the mechanism of the Heisenberg’s position-momentum uncertainty relation or by quantum entanglement. In this paper, we propose and make a systematic quantum mechanical analysis of several schemes of weak-measurement atom interferometer(WM-AI) and compare them with the historical schemes of strongmeasurement atom interferometer(SM-AI), such as Einstein’s recoiling slit and Feynman’s light microscope. As the critical part of these WM-AI setups, a weak-measurement path detector(WM-PD) deliberately interacting with the atomic internal electronic quantum states is designed and used to probe the which-path information of the atom, while only inducing negligible perturbation of the atomic center-of-mass motion. Another instrument that is used to directly interact with the atomic center-of-mass while being insensitive to the internal electronic quantum states is used to monitor the atomic centerof-mass interference pattern. Two typical schemes of WM-PD are considered. The first is the micromaser-cavity path detector, which allows us to probe the spontaneously emitted microwave photon from the incoming Rydberg atom in its excited electronic state and record unanimously the which-path information of the atom. The second is the optical-lattice Bragg-grating path detector, which can split the incoming atom beam into two different directions as determined by the internal electronic state and thus encode the which-path information of the atom into the internal states of the atom. We have used standard quantum mechanics to analyze the evolution of the atomic center-of-mass and internal electronic state wave function by directly solving Schr¨odinger’s equation for the composite atom-electron-photon system in the

关键词： wave-particle duality atom interferometers weak-measurement path-detector quantum entanglement Heisenberg’s uncertainty relation

Bionic Leaf Simulating the Thermal Effect of Natural Leaf Transpiration

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2014年第1期11卷 90-97页

作者： zhi yuan Hong Ye Shimin Li Department of Thermal Science and Energy Engineering University of Science and Technology of China Hefei 230027 P. R. China

We proposed a kind of bionic leaf to simulate the thermal effect of leaf transpiration. The bionic leaf was firstly designed to be composed of a green coating, a water holding layer, a Composite Adsorbent （CS） layer and an adsorption-desorption rate controlling layer. A thermophysical model was established for the bionic leaf, and the dynamic simulation results reveal that the water holding layer is not necessary; a CS of high thermal conductivity should be selected as the CS layer; the adsorp- tion-desorption rate controlling layer could be removed due to the low adsorption-desorption rate of the CS; and when CaC12 mass fraction of the CS reaches 40%; the bionic leaf could simulate the dynamic thermal behavior of the natural leaf. Based on the simulation results, we prepared bionic leaves with different CaC12 content. The thermographies of the bionic leaf and the natural leaf were shot using the Infrared Thermal Imager. The measured average radiative temperature difference between the bionic and natural leaves is less than 1.0 ℃.

关键词： bionic leaf composite sorbent transpiration thermal effect leaf temperature

A method to study interface diffusion of arsenic into a Nb-Ti microalloyed low carbon steel

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2012年第9期19卷 821-826页

作者： yuan-zhi Zhu Jian-ping XU The Key Laboratory of the Ministry of Education of China for Ferrous Metallurgy and Resources Utilization Wuhan University of Science and Technology Wuhan 430081 China School of Materials and Metallurgy Wuhan University of Science and Technology Wuhan 430081 China

A novel diffusion couple method was used to investigate the interface diffusion of arsenic into a Nb-Ti microalloyed low carbon steel and its effects on phase transformation at the interface. It is discovered that the content of arsenic has great effect on grain growth and phase transformation at high temperature. When the arsenic content is no more than lwt%, there is no obvious grain growth and no obvious ferrite transitional region formed at the diffusion interface. However, when the arsenic content is no less than 5wt%, the grain grows very rapidly. In addition, the arsenic-enriched ferrite transitional layer forms at the diffusion interface in the hot-rolling process, which results from a slower diffusion rate of arsenic atoms than that of carbon in ferrite.

关键词： low carbon steel alloy steel arsenic diffusion bonding phase transformation grain growth

The Heat and Mass Transfer Analysis of a Leaf

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Journal of Bionic Engineering 2013年第2期10卷 170-176页

作者： Hong Ye zhi yuan Shuanqin Zhang Department of Thermal Science andEnergy Engineering University of Science and Technology of China Hefei 230027 P. R. China The First Engineers Scientific Research Institute Wuxi 214035 P. R. China

Understanding the heat and mass transfer processes of plant leaves is essential for plant bionic engineering. A general thermophysical model was established for a plant leaf with particular emphasis on the transpiration process. The model was verified by the field measured stomatal resistance and temperature of a camphor leaf. A dynamical simulation revealed that diurnal transpiration water consumption is dominated by the solar irradiance and the day-average temperature of the leaf is dominated by the ambient air temperature; transpiration plays an important role in the cooling of the leaf, in average it could dissipate around 32.9% of the total solar energy absorbed by the leaf in summer. To imitate the thermal infared characteristic of the real leaf, the up surface of the bionic leaf must have emissivity and solar absorptivity close to those of a real leaf and its shape and surface roughness must be similar to those of the real leaf. The key point is that the bionic leaf must be able to evaporate water to simulate the transpiration of a plant leaf, appropriate adsorbent can be used to realize this function.

关键词： heat and mass transfer leaf temperature transpiration water consumption thermal infrared

Intense Two-Octave Ultraviolet-Visible-Infrared Supercontinuum Laser via High-Efficiency One-Octave Second-Harmonic Generation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research 2022年第4期2022卷 179-187页

作者： Mingzhou Li Lihong Hong zhi-yuan Li School of Physics and Optoelectronics South China University of TechnologyGuangzhou 510641China

Intense ultrabroadband laser source of high pulse energy has attracted more and more attention in physics,chemistry,biology,material science,and other *** report design and realization of a chirped periodically poled lithium niobate nonlinear crystal that supports ultrabroadband second-harmonic generation covering 350-850 nm by implementing simultaneously up to 12 orders of quasiphase matching against ultrabroadband pump laser covering 700-1700 nm with an average high conversion efficiency of about 25.8%.We obtain a flat supercontinuum spectrum with a 10 dB bandwidth covering more than one octave(about 375-1200 nm)and 20 dB bandwidth covering more than two octaves(about 350-1500 nm)in the ultraviolet-visible-infrared regime and having intense energy as 0.17 mJ per pulse through synergic action of second-order and third-order nonlinearity under pump of 0.48 mJ per pulse Ti:sapphire femtosecond *** scheme would provide a promising method for the construction of supercontinuum laser source with extremely broad bandwidth,large pulse energy,and high peak power for a variety of basic science and high technology applications.

关键词： pump Efficiency Infrared