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Deep learning based radiomics for gastrointestinal cancer diagnosis and treatment:A minireview

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World Journal of Gastroenterology 2022年第45期28卷 6363-6379页

作者： Pak Kin Wong In Neng Chan Hao-ming Yan Shan gao Chi Hong Wong Tao Yan Liang Yao Ying Hu Zhong-Ren Wang Hon Ho Yu Department of Electromechanical Engineering University of MacaoTaipa 999078MacaoChina School of Clinical Medicine China Medical UniversityShenyang 110013Liaoning ProvinceChina Department of Gastroenterology Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyang 441021Hubei ProvinceChina Faculty of Medicine Macao University of Science and TechnologyTaipa 999078MacaoChina School of Mechanical Engineering Hubei University of Arts and ScienceXiangyang 441053Hubei ProvinceChina Shenzhen Institute of Advanced Technology Chinese Academy of SciencesShenzhen 518055Guangdong ProvinceChina Department of Gastroenterology Kiang Wu HospitalMacao 999078China

Gastrointestinal(GI)cancers are the major cause of cancer-related mortality *** imaging is an important auxiliary means for the diagnosis,assessment and prognostic prediction of GI *** is an emerging and effective technology to decipher the encoded information within medical images,and traditional machine learning is the most commonly used *** advances in deep learning technology have further promoted the development of *** the field of GI cancer,although there are several surveys on radiomics,there is no specific review on the application of deep-learning-based radiomics(DLR).In this review,a search was conducted on Web of Science,PubMed,and Google Scholar with an emphasis on the application of DLR for GI cancers,including esophageal,gastric,liver,pancreatic,and colorectal ***,the challenges and recommendations based on the findings of the review are comprehensively analyzed to advance DLR.

关键词： Radiomics Deep learning Gastrointestinal cancer Medical imaging

Benign giant-cell tumor of the common bile duct:A case report

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World Journal of Gastroenterology 2014年第41期20卷 15448-15453页

作者： Dan-Dan Wang Ya-Min Zheng Liang-Hong Teng Yan-Ni Sun Wei gao Lei-ming Wang Yue-Hua Wang Fei Li De-Hong Lu Department of Pathology Xuanwu Hospital Capital Medical University Department of General Surgery Xuanwu Hospital Capital Medical University

Primary giant-cell tumors rarely arise in the common bile duct. We herein report a case of primary giant-cell tumor of the common bile duct. The patient was an 81-year-old male who was diagnosed with a well-defined 1.2-cm mass projecting into the lumen of the middle common bile duct. Excision of the gallbladder and extrahepatic bile duct and a Roux-en-Y cholangiojejunostomy were performed. Histologically, the tumor had no association with carcinomas of epithelial origin and was similar to giant-cell tumors of the bone. The tumor consisted of a mixture of mononuclear and multinucleated osteoclast-like giant cells. The mononuclear cells showed no atypical features, and their nuclei were similar to those of the multinucleated giant cells. CD68 was expressed on the mononuclear and multinucleated osteoclast-like giant cells, whereas CD163 immunoreactivity was restricted to the mononuclear cells. Six months after the operation, the patient was still alive and had no recurrence. The interest of this case lies in the rarity of this entity, the difficulty of preoperative diagnosis, and this tumor’s possible confusion with other malignant tumors.

关键词： Giant-cell tumor Common bile duct CD163 Surgical resection

Relationship between multi-slice computed tomography features and pathological risk stratification assessment in gastric gastrointestinal stromal tumors

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World Journal of Gastrointestinal Oncology 2023年第6期15卷 1073-1085页

作者： Tian-Tian Wang Wei-Wei Liu Xian-Hai Liu Rong-Ji gao Chun-Yu Zhu Qing Wang Lu-Ping Zhao Xiao-ming Fan Juan Li Department of Medical Imaging The Second Affiliated Hospital of Shandong First Medical UniversityTaian 271000Shandong ProvinceChina Department of Rheumatology The Second Affiliated Hospital of Shandong First Medical UniversityTaian 271000Shandong ProvinceChina Department of Network Information Center The Second Affiliated Hospital of Shandong First Medical UniversityTaian 271000Shandong ProvinceChina Department of Ultrasound The Second Affiliated Hospital of Shandong First Medical UniversityTaian 271000Shandong ProvinceChina Department of Medical Imaging The Affiliated Hospital of Ji’ning Medical UniversityJining 272000Shandong ProvinceChina

BACKGROUND Computed tomography(CT)imaging features are associated with risk stratification of gastric gastrointestinal stromal tumors(GISTs).AIM To determine the multi-slice CT imaging features for predicting risk stratification in patients with primary gastric *** The clinicopathological and CT imaging data for 147 patients with histologically confirmed primary gastric GISTs were retrospectively *** patients had received dynamic contrast-enhanced CT(CECT)followed by surgical *** to the modified National Institutes of Health criteria,147 lesions were classified into the low malignant potential group(very low and low risk;101 lesions)and high malignant potential group(medium and high-risk;46 lesions).The association between malignant potential and CT characteristic features(including tumor location,size,growth pattern,contour,ulceration,cystic degeneration or necrosis,calcification within the tumor,lymphadenopathy,enhancement patterns,unenhanced CT and CECT attenuation value,and enhancement degree)was analyzed using univariate *** logistic regression analysis was performed to identify significant predictors of high malignant *** receiver operating curve(ROC)was used to evaluate the predictive value of tumor size and the multinomial logistic regression model for risk *** There were 46 patients with high malignant potential and 101 with low-malignant potential gastric *** analysis showed no significant differences in age,gender,tumor location,calcification,unenhanced CT and CECT attenuation values,and enhancement degree between the two groups(P>0.05).However,a significant difference was observed in tumor size(3.14±0.94 vs 6.63±3.26 cm,P<0.001)between the low-grade and high-grade *** univariate analysis further revealed that CT imaging features,including tumor contours,lesion growth patterns,ulceration,cystic degeneration or necrosis,lymphadenopathy,and contrast enhance

关键词： Computed tomography Gastrointestinal stromal tumor Risk stratification,Stomach

Effectiveness of enhanced recovery after surgery in the perioperative management of patients with bone surgery in China

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World Journal of Clinical Cases 2021年第33期9卷 10151-10160页

作者： Li-Yan Zhao Xiong-Tao Liu Zhi-Li Zhao Ru Gu Xiu-Mei Ni Rui Deng Xiao-Ying Li ming-Ji gao Wei-Na Zhu Department of Anesthesiology The Second Affiliated Hospital of Xi’an Jiaotong UniversityXi'an 710004Shaanxi ProvinceChina Department of Anesthesiology PLA Air Force 986 HospitalXi'an 710054Shaanxi ProvinceChina

BACKGROUND Enhanced recovery after surgery(ERAS)was introduced in China in *** time,the scope of ERAS has expanded from abdominal surgery to orthopedics,urology and other *** development and research has contributed to progress of ERAS in *** 2019,to promote the application of ERAS in bone tumor surgery,we formed the“Consensus of Experts on Perioperative Management of Accelerated Rehabilitation in Major Surgery of Bone Tumors in China”.AIM To evaluate the effect of enhanced recovery after bone tumor surgery in perioperative management in *** One hundred and seven patients who underwent bone tumor surgery at the Second Affiliated Hospital of Xi’an Jiaotong University between May 2019 and April 2021 were randomized into a study group(53 cases)and a control group(54 cases).The study group adopted the ERAS protocol and the control group adopted conventional *** outcome measures included postoperative length of stay(LOS),postoperative complications,mortality,and 30-d readmission *** outcomes included postoperative visual analog scale(VAS)score of pain,number of blood transfusions,drainage volume in 24 h after operation,patient satisfaction 30 d after discharge,VAS score at 30 d after discharge,and daily standing walking *** There were no significant differences in the baseline data,clinical features and surgical site between the two *** LOS in the study group with the ERAS protocol was 7.72±3.34 d compared with 10.28±4.27 d in the control group who followed conventional *** incidence of postoperative nausea and vomiting(PONV)in the study group was 19%and 37%in the control *** VAS scores of pain on postoperative day 1(POD1)and POD3 in the study group were 4.79±2.34 and 2.79±1.53 compared with 5.28±3.27 and 3.98±2.27 in the control *** drainage volume in 24 h after the operation was 124.36±23.43 mL in the study group and 167.43±30.87 mL in the control *** number of blood transfusion

关键词： Enhanced recovery after surgery Bone tumor surgery Perioperative management Effect evaluation Clinical application

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产油微藻胁迫培养策略研究综述

中国环境科学 2021年第8期41卷 3853-3866页

作者：聂煜东耿媛媛张贤明蒋光明重庆工商大学废油资源化技术与装备教育部工程研究中心重庆400067 重庆理工大学化学化工学院重庆400054 中国科学院生态环境研究中心环境水质学国家重点实验室北京100085

围绕微藻的胁迫培养,介绍了不同胁迫手段影响下产油微藻的生长及产油特点,对比了不同胁迫手段下微藻产油效果及各手段优劣势,在此基础上进一步综述了各因素胁迫在微藻油脂合成代谢中的作用机理,并给出了各胁迫手段在实际生产中的选用建... 详细信息

围绕微藻的胁迫培养,介绍了不同胁迫手段影响下产油微藻的生长及产油特点,对比了不同胁迫手段下微藻产油效果及各手段优劣势,在此基础上进一步综述了各因素胁迫在微藻油脂合成代谢中的作用机理,并给出了各胁迫手段在实际生产中的选用建议.以期通过该综述,对微藻生物柴油产业化中相关胁迫策略的选择提供借鉴.

关键词：生物柴油产油微藻胁迫培养代谢机理

基于链路生命期的光数据中心网络业务恢复方案

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通信学报 2018年第8期39卷 125-132页

作者：鲍宁海袁园刘自谦匡明重庆邮电大学通信与信息工程学院重庆400065

针对大规模灾难事件对光数据中心网络造成的关联性和级联性故障,提出一种基于链路生命期的灾后业务恢复方案。该方案利用全局业务带宽退让和局部链路的有限生命期,缓解灾后网络的带宽资源危机,根据灾难损毁业务的带宽需求和持续时间需求... 详细信息

针对大规模灾难事件对光数据中心网络造成的关联性和级联性故障,提出一种基于链路生命期的灾后业务恢复方案。该方案利用全局业务带宽退让和局部链路的有限生命期,缓解灾后网络的带宽资源危机,根据灾难损毁业务的带宽需求和持续时间需求,确定业务恢复优先级,采用任播与多播相结合的路由策略提高业务的连通性和带宽资源利用率。仿真结果表明,所提方案能够最大限度地降低业务中断率,并有效地延长灾难损毁业务的持续时间,减少数据流量损失。

关键词：光数据中心网络链路生命期网络生存性业务恢复业务持续时间

Cross-linkable fullerene interfacial contacts for enhancing humidity stability of inverted perovskite solar cells

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Rare Metals 2021年第7期40卷 1691-1697页

作者： ming-Wei An Zhou Xing Bao-Shan Wu Fang-Fang Xie Shan-Yu Zheng Lin-Long Deng Xu Wang Bin-Wen Chen Da-Qin Yun Su-yuan Xie Rong-Bin Huang Lan-Sun Zheng State Key Laboratory for Physical Chemistry of Solid Surfaces iChEM(Collaborative Innovation Center of Chemistry for Energy Materials)Department of ChemistryCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005China Pen-Tung Sah Institute of Micro-Nano Science and Technology Xiamen UniversityXiamen 361005China College of Energy Xiamen UniversityXiamen 361005China

In situ cross-linking encapsulation has been demonstrated to be an efficient strategy for enhancing the humidity stability of perovskite solar cells(PSCs).In this study,a novel cross-linkable fullerene derivative,namely1-(p-benzoate-(p-methylvinylbenzene)-indolino[2,3][60]fullerene(FPPS),was readily synthesized from commercially available building blocks in two *** FPPS was employed as an interfacial modifier on perovskite surfaces in inverted planar p-i-n *** to the fast interfacial charge extraction and efficient trap passivation,PSCs based on the cross-linked FPPS(C-FPPS)exhibited excellent *** PSCs had a top-performing power conversion efficiency(PCE)of 17.82%with negligible hysteresis,compared to the control devices without C-PFFS(16.99%).Moreover,the strong water resistance of the C-FPPS interfacial layer distinctly enhances the ambient stability of PSC devices,exhibiting a t80(the time required to reach 80%of the initial PCE)of 300 h under high-humidity *** significantly surpasses the control devices,whose t80 was only 130 *** results demonstrate that cross-linkable fullerene derivatives can be promising interfacial materials for designing high-efficiency,hysteresis-free,air-stable PSCs.

关键词： Perovskite solar cells Cross-linkable fullerene Fullerene interlayer Power conversion efficiency Humidity stability

Metabolism Kinetics of Glucose in Anchorage-dependent Cell Cultures

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过程工程学报 2001年第4期1卷 387-393页

作者：孙祥明张元兴华东理工大学生物反应器工程国家重点实验室上海 200237

The kinetic model of glucose metabolism was established and successfully applied to batch cultures of rCHO and rBHK cells. It was found that a large amount of glucose was utilized for cell maintenance, and the overwhelming majority of maintenance energy from glucose was by its anaerobic metabolism in both rBHK and rCHO cell cultures. The overall maintenance coefficients from aerobic metabolism were 1.910-13 mmol/(cell穐) for rCHO cells and 710-13 mmol/(cell穐) for rBHK cells. In addition, all GO/T and EO/T gradually increased with the same trend as the cell growth in the culture of both rCHO and rBHK cells. The overall molecule yield coefficients of lactate to glucose were 1.61 for rCHO cells and 1.38 for rBHK cells. The yield coefficients of cell to glucose were 4.5108 cells/mmol for rCHO cells and 1.9 108 cells/mmol for rBHK cells, respectively.

关键词：动物细胞细胞培养新陈代谢动力学葡萄糖

“后马克思主义”理论视域中的“领导权”概念探析

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中共福建省委党校学报 2009年第12期 11-16页

作者：高远福建江夏学院福建福州350108

"后马克思主义"从葛兰西的"领导权"概念入手,对当代西方资本主义社会的经济、政治、文化三大层面的"领导权"问题进行了较为深入的话语分析,突出强调了争取文化领导权的重要性,在此基础上提出了有别于传统马克思主义的新的"社会主义策略... 详细信息

"后马克思主义"从葛兰西的"领导权"概念入手,对当代西方资本主义社会的经济、政治、文化三大层面的"领导权"问题进行了较为深入的话语分析,突出强调了争取文化领导权的重要性,在此基础上提出了有别于传统马克思主义的新的"社会主义策略"。但是建立在话语分析基础上的"后马克思主义"的争取"领导权"策略,由于缺乏现实性和可操作性,只能成为一种可望而不可及的美丽构想。

关键词：后马克思主义市民社会领导权葛兰西拉克劳和墨菲