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Vascular reconstruction provides short-term and long-term survival benefits for patients with hilar cholangiocarcinoma:A retrospective,multicenter study

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Hepatobiliary & pancreatic Diseases International 2024年第6期23卷 595-603页

作者： Yi-Xian Huang chao Xu Cheng-Cheng Zhang Guang-Yi Liu Xing-chao Liu Hai-Ning Fan Bi pan yuan-Cheng Li Department of Hepatobiliary Surgery Southwest HospitalThird Military Medical University(Army Medical University)Chongqing 400038China Department of Hepatobiliary Surgery Liaocheng People’s HospitalLiaocheng 252000China Sichuan Academy of Medical Sciences&Sichuan Provincial People’s Hospital Chengdu 610000China Qinghai University Affiliated Hospital Xining 810016China

Background:In patients with hilar cholangiocarcinoma(HCCA),radical resection can be achieved by resection and reconstruction of the ***,whether vascular reconstruction(VR)improves long-term and short-term prognosis has not been demonstrated ***:This was a retrospective multicenter study of patients who received surgery for HCCA with or without *** associated with overall survival(OS)and recurrence-free survival(RFS)were identified based on Cox ***-Meier curves were used to explore the impact of *** mean survival time(RMST)was used for comparisons of short-term survival between the ***’intraoperative and postoperative characteristics were ***:Totally 447 patients were *** divided these patients into 3 groups:VR with radical resections(n=84);non-VR radical resections(n=309)and non-radical resection(we pooled VRnonradical and non-VR nonradical together,n=54).Cox regression revealed that carbohydrate antigen 242(CA242),vascular invasion,lymph node metastasis and poor differentiation were independent risk factors for OS and *** was no significant difference of RMST between the VR and non-VR radical groups within 12 months after surgery(10.18 vs.10.76 mon,P=0.179),although the 5-year OS(P<0.001)and RFS(P<0.001)were worse in the VR radical *** incidences of most complications were not significantly different,but those of bile leakage(P<0.001)and postoperative infection(P=0.009)were higher in the VR radical group than in the non-VR radical ***,the levels of alanine aminotransferase(ALT)and aspartate aminotransferase(AST)up to 7 days after surgery tended to decrease in all *** was no significant difference in the incidence of postoperative liver failure between the VR and non-VR radical ***:Radical resection can be achieved with VR to improve the survival rate without worsening short-term survival compared with resection wit

关键词： Hilar cholangiocarcinoma Hepatectomy Vascular reconstruction Prognosis

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A fast and reliable overset unstructured grids approach

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Acta Mechanica Sinica 2013年第2期29卷 149-157页

作者： Zhong-Liang Kang chao Yan Jian Yu yuan-yuan Fang Institute of Fluid Mechanics Beihang University Academy of Beijing Gas GroupCo. Ltd

A cell-centred overset unstructured grids approach is *** this approach,the intergrid boundary is initially established based on the wall distance from the cell centre,and is then *** accelerate the intergrid-boundary definition much more,a neighbor-toneighbor donor search algorithm based on advancing-front method is modified with the help of minimum cuboid *** simplify the communications between different grid cell types and to obtain second-order spatial accuracy,a new interpolation method is constructed based on linear reconstruction,which employs only one layer of fringe cells along the intergrid *** unsteady flows with relative motion,the intergrid boundary can be redefined fast and *** numerical results show that the present dynamic overset unstructured grids approach is accurate and reliable.

关键词： Overset unstructured grids·Dynamic grids·Intergrid-boundary definition·Interpolation

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Prospective study of the effect of ERAS on postoperative recovery and complications in patients with gastric cancer

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Cancer Biology & Medicine 2022年第8期19卷 1274-1281页

作者： Ye Tian Qiang Li yuan pan Tianjin Medical University Cancer Institute and Hospital National Clinical Research Center for CancerKey Laboratory of Cancer Prevention and TherapyTianjinTianjin’s Clinical Research Center for CancerTianjin 300060China

Objective:To study the efficacy of the enhanced recovery after surgery(ERAS)program on postoperative recovery and complications in patients with gastric ***:Eighty patients in the perioperative period with radical gastrectomy were enrolled and randomly divided into 2 groups,the ERAS group and the non-ERAS *** differences between the 2 groups in terms of postoperative recoveries and complications rate were *** to the body mass index(BMI)level,the ERAS group was divided into 2 subgroups,namely group A(BMI<28 kg/m2,n=16)and group B(BMI≥28 kg/m2,n=24).The non-ERAS group was also divided into group C(BMI<28 kg/m2,n=18)and group D(BMI≥28 kg/m2,n=22).The recovery and complications of each group were then ***:The postoperative length of stay and visual analogue scale pain score were less in the ERAS group than the non-ERAS group(P<0.05).Time to first postoperative exhaustion,first postoperative defecation,returning leukocyte count to normal,and stopping intravenous nutrition were significantly shorter in the ERAS group(n=40),compared to the non-ERAS group(n=40,all P<0.05).The incidence of postoperative lower extremity intramuscular venous thrombosis was significantly higher in group D than in group B(χ2=4.800,P=0.028).In addition,the incidence of lower extremity intermuscular venous thrombosis and lung infection in group D was higher than those in other ***:The perioperative ERAS program was associated with faster recovery in patients undergoing radical *** patients with higher BMI(BMI≥28 kg/m2),the use of the perioperative ERAS program was more advantageous.

关键词： Enhanced recovery after surgery body mass index gastric cancer laparoscope complication

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Effect of calcium content on inclusions during the ladle furnace refining process of AISI 321 stainless steel

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International Journal of Minerals,Metallurgy and Materials 2020年第11期27卷 1499-1507页

作者： chao pan Xiao-jun Hu Jian-chao Zheng Ping Lin Kuo-chih Chou State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China School of Metallurgy Northeastern UniversityShenyang 110819China Ruipu Technology Group Co. Ltd.Qingtian 323903China

The effect of three heat processes with different calcium contents on the evolution of inclusions during the ladle furnace refining process of AISI 321 stainless steel was *** size,morphology,and composition of the inclusions were analyzed by scanning electron microscopy and energy-dispersive X-ray *** the addition of aluminum and titanium,the primary oxide in the AISI 321 stainless steel was an AbOs—MgO—TiOx complex oxide,in which the mass ratio of AbOs/MgO was highly consistent with spinel(MgO・AbO3).After calcium treatment,the calcium content in the oxide increased *** calculations show that when the Ti content was 0.2wt%,the Al and Ca contents were less than 0.10wt%and 0.0005wt%,respectively,which was beneficial for the formation of liquid inclusions in molten ***,the modification mechanism of calcium on TiN-wrapped oxides in combination with temperature changes was discussed.

关键词： inclusions stainless steel calcium treatment thermodynamic calculation

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Pollen Morphology of the Platycodonoid Group (Campanulaceae ***.) and Its Systematic Implications

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Journal of Integrative Plant Biology 2012年第10期54卷 773-789页

作者： HONG De-yuan pan Kai-Yu State Key Laboratory of Systematic&Evolutionary Botany Institute of BotanyThe Chinese Academy of SciencesChina

In this study, we examined the pollen morphology of the platycodonoid group in Campanulaceae s. str. using a scanning electronic microscope. We used pollen grains of 25 accessions representing 24 species of the Codonopsis complex （including Campanumoea, Cyclocodon, Leptocodon, and all three subgenera of Codonopsis）, which is extremely controversial among authors for taxonomic treatment. Pollen morphology of all the other genera in the group observed by previous authors is taken into account in our discussion. A total of nine pollen types with two subtypes in the group were recognized and named for the first time. Molecular and morphological data imply that each pollen type corresponds to a natural group at generic level, and thus the mergence of Leptocodon with Codonopsis and the restoration of Cyclocodon as a separate genus are justifiable, and Codonopsis subg. Pseudocodonopsis, subg. Obconicicapsula, and two species of Codonopsis subg. Codonopsis （C. purpurea and C. chimiliensis） may be better classified as three independent genera separate from the core Codonopsis.

关键词： Campanulaceae s. str. platycodonoid group Codonopsis complex pollen morphology pollen type taxonomy systematics.

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Late-Time Evolution of the Phantom Scalar Perturbation in the Background of a Spherically Symmetric Static Black Hole

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Chinese Physics Letters 2010年第6期27卷 9-12页

作者： pan Qi-yuan JING Ji-Liang Institute of Physics and Department of Physics Hunan Normal University Changsha 410081

The late-time evolution of the phantom scalar perturbation is investigated in the spacetime of a four-dimensionai spherically symmetric static black hole. It is revealed that the asymptotic tail of the phantom scalar field is dominated by the growth behavior t-（l＋3/2）eμt, which depends on the multipole moment l and the field moss but is independent of the mass M and charge Q of the black hole. This growth behavior is in strong contrast to the decaying tall of the usual massive scalar perturbation and shows that the external phantom scalar perturbation is unstable in the spherically symmetric static black hole spacetime.

关键词： Limonium sinuatum Growth Tail Fields

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Reconstructing early transmission networks of SARS-CoV-2 using a genomic mutation model

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Zoological Research 2023年第3期44卷 494-504页

作者： chao-yuan Cheng Zhi-Bin Zhang State Key Laboratory of Integrated Management of Pest Insects and Rodents Institute of ZoologyChinese Academy of SciencesBeijing 100101China CAS Center for Excellence in Biotic Interactions University of Chinese Academy of SciencesBeijing 100049China

The coronavirus disease 2019(COVID-19)pandemic has greatly damaged human society,but the origins and early transmission patterns of the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pathogen remain ***,we reconstructed the transmission networks of SARS-CoV-2 during the first three and six months since its first report based on ancestor-offspring relationships using BANAL-52-referenced *** explored the position(i.e.,root,middle,or tip)of early detected samples in the evolutionary tree of *** total,6799 transmission chains and 1766 transmission networks were reconstructed,with chain lengths ranging from 1-9 *** root node samples of the 1766 transmission networks were from 58 countries or regions and showed no common ancestor,indicating the occurrence of many independent or parallel transmissions of SARS-CoV-2 when first detected(i.e.,all samples were located at the tip position of the evolutionary tree).No root node sample was found in any sample(n=31,all from the Chinese mainland)collected in the first 15 days from 24 December *** using six-month data or RaTG13-referenced mutation data were *** reconstruction method was verified using a simulation *** results suggest that SARS-CoV-2 may have already been spreading independently worldwide before the outbreak of COVID-19 in Wuhan,***,a comprehensive global survey of human and animal samples is essential to explore the origins of SARS-CoV-2 and its natural reservoirs and hosts.

关键词： SARS-CoV-2 Transmission chain Transmission network Ancestor-offspring relationship De novo mutation Back mutation Secondary mutation

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Sedimentation behavior of indoor airborne microparticles

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Journal of China University of Mining and Technology 2008年第4期18卷 588-593页

作者： LIMing WU chao pan Wei School of Resources and Safety Engineering Central South University Changsha Hunan 410083 China

Experiments on the behavior of airborne microparticle sediments and their adhesion on glass slides were conducted in a laboratory located on the first floor of a teaching building. Clean tiles and glass slides were placed at different angles （0°, 45° and 90°） with respect to the horizontal plane in the laboratory. The sedimentation of microparticles was investigated at certain time intervals （1 d, 3 d, l0 d and 30 d）. The results of testing, at day 30, show that the diameters of particles on the horizontal tiles varied from 20 to 80 μm; few particles with diameter less than 0.5 μm or greater than 100 μm were found. The amount of particle sediment on all the slides increased along over time, while the average diameter of particles was not correlated with time, nor with the angle of placement. The maximum particle size, the total particle surface area, the total perimeter of all particles and the cover ratio of light （the proportion of total area of particles to the observed area of the slides surfaces） did not change significantly within the first 10 days. Inspection of all the samples for the last 20 days, however, showed that these variables increased substantially with the passage of time and were in reverse proportion to the placement angles, which indicates a concentration of particles, as well as physical and chemical changes.

关键词： particle sedimentation size distribution surface indoor air

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Robust Nonparametric Function Estimation for Errors-in-variables Models

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Acta Mathematicae Applicatae Sinica 2020年第2期36卷 314-331页

作者： chao-xia yuan Heng-jian CUI School of Mathematical Sciences Capital Normal UniversityBeijing 100048China

This paper discusses robust nonparametric estimators of location regression function for errorsin-variables model with de-convolution *** local constant smoother is used for the estimation of the nonparametric function,and the local linear smoother is proposed to deal with the boundary problem,as well as to improve the local constant *** establish the asymptotic properties of the estimator,the influence function of the statistical functional and the breakdown point.A simulation study is carried out to demonstrate robust performance of the proposed *** motorcycle data is presented to illustrate the application of the robust estimator further.

关键词： errors-in-variables de-convolution kernel robust local linear

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Hybrid bioartificial liver support in cynomolgus monkeys with D-galactosamine-induced acute liver failure

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World Journal of Gastroenterology 2014年第46期20卷 17399-17406页

作者： Zhi Zhang Yi-chao Zhao yuan Cheng Guo-Deng Jian Ming-Xin pan Yi Gao Second Department of Hepatobiliary Zhujiang HospitalSouthern Medical University Department of Hepatobiliary Tangshan Gongren Hospital Chancheng District Central Hospital Guangdong Province Institute of Regenerative Medicine Zhujiang HospitalSouthern Medical University

AIM: To evaluate a hybrid bioartificial liver support system (HBALSS) in cynomolgus monkeys with acute liver failure.

关键词： Acute liver failure Chinese human liver cells Cynomolgus monkey Human liver cell Hybrid bioartificial liver

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