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集体养老人群中微量白蛋白尿与24 h尿钠、尿钾及钠钾比相关性研究

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现代预防医学 2024年第6期51卷 1094-1098页

作者：段培芬郝嘉琪原建慧冯向先长治医学院公共卫生与预防医学系长治医学院第二临床学院

目的了解集体养老人群24 h尿钠、尿钾、钠钾比与微量白蛋白尿(microalbuminuria, MAU)的关系。方法采用随机整群抽样方法于2017年9月至2017年11月在山西省东南部地区16家养老机构进行问卷调查、体格检查、血液及24 h尿液标本收集。采... 详细信息

目的了解集体养老人群24 h尿钠、尿钾、钠钾比与微量白蛋白尿(microalbuminuria, MAU)的关系。方法采用随机整群抽样方法于2017年9月至2017年11月在山西省东南部地区16家养老机构进行问卷调查、体格检查、血液及24 h尿液标本收集。采用多因素非条件logistic回归分析24 h尿钠、尿钾、钠钾比与微量白蛋白尿的相关性。结果本次纳入研究对象502人，平均年龄为65.77±8.54岁，男性467人(93.03%),24小时尿钠、尿钾、钠钾比分别为(193.02±87.64) mmol、(27.95±15.02) mmol、(7.44±2.62),MAU者33人(6.57%);多因素logistic回归分析显示：较高的24 h尿钠与钠钾比水平(Q4)与最低水平(Q1)相比，MAU的发生风险增加(OR=4.026,95%CI:1.045～15.515;OR=4.043,95%CI:1.252～13.057)。结论 MAU的发生与24 h尿钠、钠钾比呈正相关，而与24 h尿钾无关。

关键词： 24 h尿钠 24 h尿钾钠钾比微量白蛋白尿

Shallow Donor Impurity Ground State in a GaAs/AlAs Spherical Quantum Dot within an Electric Field

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Communications in Theoretical Physics 2009年第10期52卷 710-714页

作者： yuan jian-hui XIE Wen-Fang HE Li-Li Department of Physics College of Physics and Electronic Engineering Guangzhou University Guangzhou 510006 China

Using the configuration-integration methods （CI） [Phys. Rev. B 45 （1992） 19], we report the results of the Hydrogenie-impurity ground state in a GaAs/AIAs spherical quantum dot under an electric field. We discuss the variations of the binding energies of the Hydrogenic-impurity ground state as a function of the position of impurity D, the radius R of the quantum dot, and also as a function of electric field F. We find that the ground energy and binding energy of impurity placed anywhere depend strongly on the position of impurity. Also, electric field can largely change the Hydrogenic-impurity ground state only limiting to the big radius of quantum dot. And the differences in energy level and binding energy are observed from the center donor and off-center donor.

关键词： donor quantum dots binding energy electric field

PRESSURE DISTRIBUTION ON THE WALL OF THE INNER CYLINDER RECIPROCATING AXIALLY TO THE UNSTEADY FLOW OF VISCOELASTIC FLUID IN ECCENTRIC ANNULUS

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Journal of Hydrodynamics 2006年第5期18卷 606-612页

作者： WANG Yan CUI Hai-qing YANG yuan-jian GUO Jun-hui LI Nan Department of Petroleum Engineering China University of Petroleum Beijing 102249 China Department of Petroleum Engineering Daqing Petroleum Institute Daqing 163318 China

In this article, the governing equations for the unsteady flow of viscoelastic fluid in the eccentric annulus with the inner cylinder reciprocating axially and the expression of the pressure distribution on the wall of the inner cylinder of the annulus are established and derived, respectively, under the bipolar coordinate system. The equations and the expression are solved and calculated numerically using the finite difference method, respectively. The curves of the pressure distribution on the wall of the inner cylinder of the aqueous solution of Hydrolyzed Polyacrylamide （HPAM） are plotted and the influences of annular eccentricity, stroke, and stroke frequency on the pressure distribution are analyzed.

关键词： viscoelastic unsteady flow eccentric annulus fluid reciprocating axially pressure distribution

Understanding the Thermal Impedance of Silicone Rubber/Hexagonal Boron Nitride Composites as Thermal Interface Materials

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Chinese Journal of Polymer Science 2024年第3期42卷 352-363,I0008页

作者： yuan Ji Shi-Da Han Hong Wu Shao-Yun Guo Feng-Shun Zhang jian-hui Qiu The State Key Laboratory of Polymer Materials Engineering Sichuan Provincial Engineering Laboratory of Plastic/Rubber Complex Processing TechnologyPolymer Research InstituteSichuan UniversityChengdu 610065China Institute of Chemical Materials China Academy of Engineering PhysicsMianyang 621900China Department of Mechanical Engineering Faculty of Systems Science and TechnologyAkita Prefectural UniversityAkita 015-0055Japan

Silicone rubber(SR) composites are most widely used as thermal interface materials(TIMs) for electronics heat dissipation. Thermal impedance as the main bottleneck limiting the performance of TIMs is usually neglected. Herein, the thermal impedance of SR composites loaded with different levels of hexagonal boron nitride(h-BN) as TIMs was elaborated for the first time by the ASTM D 5470 standard test and finite element analysis. It was found that elastic modulus and surface roughness of SR composites increased with the increase of h-BN content, indicating that the conformity was reduced. When the assembly pressure was 0.69 MPa, there existed an optimal h-BN content at which the contact resistance was minimum(0.39 K·cm^(2)·W^(-1)). Although the decreased bond line thickness(BLT) by increasing the assembly pressure was beneficial to reduce the thermal impedance, the proper assembly pressure should be selected to prevent the warpage of the contact surfaces and the increase in contact resistance, according to the compression properties of the SR composites. This study provides valuable insights into fabrication of high-performance TIMs for modern electronic device applications.

关键词： Thermal interface materials Hexagonal boron nitride Thermal impedance Surfaces

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单壁碳纳米管弹性性质的羟基接枝效应

物理学报 2008年第6期57卷 3666-3673页

作者：袁剑辉袁晓博长沙理工大学物理与电子科学学院长沙410076 长沙理工大学电气与信息工程学院长沙410076

用分子动力学方法研究了端口接枝不同数量羟基对扶手椅型和锯齿型单壁碳纳米管弹性模量的影响.结果表明,未接枝的扶手椅型(5,5),(10,10)管和锯齿型(9,0),(18,0)管杨氏模量分别为948,901和804,860GPa.在接枝2—8个羟基情况下,锯齿型单壁... 详细信息

用分子动力学方法研究了端口接枝不同数量羟基对扶手椅型和锯齿型单壁碳纳米管弹性模量的影响.结果表明,未接枝的扶手椅型(5,5),(10,10)管和锯齿型(9,0),(18,0)管杨氏模量分别为948,901和804,860GPa.在接枝2—8个羟基情况下,锯齿型单壁碳纳米管拉伸杨氏模量基本不随接枝数量增加发生变化,而扶手椅单壁碳纳米管则不同,接枝状态下的弹性模量比未接枝状态小很多,但接枝一定数量后,其杨氏模量又略增到某一稳定值.分别从接枝后碳纳米管变形电子密度等值线结构、C—C键长和系统结合能变化规律等方面,对单壁碳纳米管弹性模量的接枝效应进行了分析.

关键词：碳纳米管羟基接枝效应杨氏模量

Pathogen-induced methylglyoxal negatively regulates rice bacterial blight resistance by inhibiting OsCDR1 protease activity

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Molecular Plant 2024年第2期17卷 325-341页

作者： Zheng-Wei Fu jian-hui Li Xiang Gao Shi-Jia Wang Ting-Ting yuan Ying-Tang Lu State Key Laboratory of Hybrid Rice College of Life SciencesRenmin Hospital of Wuhan UniversityWuhan UniversityWuhan 430072China Key Laboratory of Biology and Genetic Improvement of OilCrops Ministry of Agriculture and Rural AffairsOilCrops Research Institute of the Chinese Academy of Agricultural SciencesWuhan 430062China

Xanthomonas oryzae ***(Xoo)causes bacterial blight(BB),a globally devastating disease of rice(Oryza sativa)that is responsible for significant crop *** and sugar metabolites are important for pathogen infection,providing energy and regulating events associated with defense responses;howev-er,the mechanisms by which they regulate such events in BB are *** an inevitable sugar metabolite,methylglyoxal(MG)is involved in plant growth and responses to various abiotic stresses,but the underlying mechanisms remain *** and how MG functions in plant biotic stress responses is almost completely ***,we report that the Xoo strain PXO99 induces OsWRKY62.1 to repress transcrip-tion of OsGLY Il genes by directly binding to their promoters,resulting in overaccumulation of *** negatively regulates rice resistance against Pxo99:osglyll2 mutants with higher MG levels are more sus-ceptible to the pathogen,whereas OsGLYIl2-overexpressing plants with lower MG content show greater resistance than the wild *** of OsGLYll2 to prevent excessive MG accumulation confers broad-spectrum resistance against the biotrophic bacterial pathogens Xoo and Xanthomonas oryzae *** and the necrotrophic fungal pathogen Rhizoctonia solani,which causes rice sheath *** evidence shows that MG reduces rice resistance against PXO99 through CONSTITUTIVE DISEASE RESISTANCE 1(OsCDR1).MGmodifies the Arg97 residue of OsCDR1to inhibit its aspartic protease activ-ity,which is essential for OsCDR1-enhanced *** together,these findings illustrate how Xoo promotes infection by hijacking a sugar metabolite in the host plant.

关键词： Oryza sativa bacterial blight OsWRKY62.1 methylglyoxal OsCDR1

Global Spherically Symmetric Solutions for a Coupled Compressible Navier–Stokes/Allen–Cahn System

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Acta Mathematica Sinica,English Series 2024年第8期40卷 2037-2064页

作者： Chang Ming SONG jian Lin ZHANG yuan yuan WANG Department of Applied Mathematics School of Mathematics and Information ScienceZhongyuan University of TechnologyZhengzhou 450007P.R.China

In this paper,we consider the global spherically symmetric solutions for the initial boundary value problem of a coupled compressible Navier–Stokes/Allen–Cahn system which describes the motion of two-phase viscous compressible *** prove the existence and uniqueness of global classical solution,weak solution and strong solution under the assumption of spherically symmetry condition for initial dataρ0 without vacuum state.

关键词： Diffuse interface model global solutions Navier-Stokes equations Allen-Cahn equation spherically symmetry

Neg-Entropy Mechanism as a Target for Natural Medicines

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Engineering 2024年第7期38卷 11-12页

作者： Tian-Le Gao hui-hui Guo jian-Dong jiang Institute of Materia Medica Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100050China

Current strategies for drug discovery research mainly focus on molecular targets,in which structure biology plays a central role,such as the detailed mechanism of a drug-target *** principle of this approach is the presumed molecular mechanism or genetic background of the disease being *** this approach has brought progress in understanding the mode of action for some drugs,most prevalent illnesses-especially chronic diseases-are multifactorial and present with a group of symptoms,as is often the case in cardiovascular diseases,metabolic disorders,cancers,and so *** newly emerging term“multi-morbidity”(i.e.,multiple co-occurring diseases)describes a grand challenge for this strategy,and successful drug intervention for multimorbidity should be multifaceted[1].So,our research team has shifted its attention to a new direction that views the disease as a whole instead of a single-molecule abnormality,and focusing on drugs with multiple targets.

关键词： drugs diseases cardiovascular

Natural forests exhibit higher organic carbon concentrations and recalcitrant carbon proportions in soil than plantations:a global data synthesis

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Journal of Forestry Research 2024年第5期35卷 131-141页

作者： Xiuqing Nie hui Wang jian Wang Shirong Liu Ecology and Nature Conservation Institute Chinese Academy of ForestryKey Laboratory of Forest Ecology and Environment of National Forestry and Grassland AdministrationNo.2 DongxiaofuHaidian DistrictBeijing 100091People’s Republic of China

Different chemical compositions of soil organic carbon(SOC)affect its persistence and whether it signifi-cantly differs between natural forests and plantations remains *** synthesizing 234 observations of SOC chemical compositions,we evaluated global patterns of concentra-tion,individual chemical composition(alkyl C,O-alkyl C,aromatic C,and carbonyl C),and their distribution *** results indicate a notably higher SOC,a markedly larger proportion of recalcitrant alkyl C,and lower easily decomposed carbonyl C proportion in natural ***-ever,SOC chemical compositions were appreciably more evenly distributed in *** on the assumed con-ceptual index of SOC chemical composition evenness,we deduced that,compared to natural forests,plantations may have higher possible resistance to SOC decomposition under *** tropical regions,SOC levels,recalcitrant SOC chemical composition,and their distributed evenness were significantly higher in natural forests,indicating that SOC has higher chemical stability and possible resistance to *** factors had minor effects on alkyl C in forests globally,while they notably affected SOC chemi-cal composition in tropical *** could contribute to the differences in chemical compositions and their distrib-uted evenness between plantations and natural stands.

关键词： Global data synthesis Natural forest Plantations Soil organic carbon Soil organic carbon chemical composition