检索结果-南通市图书馆

Cronkhite-Canada syndrome:Report of six cases and review of literature

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2014年第23期20卷 7518-7522页

作者： Xiao-Heng Wen Lan wang yu-xuan wang Jia-Ming Qian Department of Gastroenterology Peking Union Medical College HospitalChinese Academy of Medical Sciences Department of Behavioral Sciences and Health Education Rollins School of Public HealthEmory University

Cronkhite-Canada syndrome(CCS)is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances in the gastrointestinal tract and *** aim of this study was to investigate the clinical features and potential therapies for *** patients with CCS admitted from December 1992 to July 2008 to Peking Union Medical College Hospital were *** patients had clinical manifestation of nonhereditary gastrointestinal polyposis with diarrhea,skin hyperpigmentation,alopecia,and nail *** occult blood was positive in all six *** hemoglobin,potassium,calcium and protein were below the normal range in two ***-Saccharomyces cerevisiae and antinuclear antibodies were present in three *** polyps were found in all patients by gastroscopy and colonoscopy,with only one in the ***,there were hyperplastic polyps in five cases,tubular adenoma in three,and juvenile polyp in one with chronic inflammation and mucosal *** treatment led by corticosteroids can result in partial remission of clinical symptoms,and longterm follow-up is necessary.

关键词： Cronkhite-Canada syndrome Clinical feature Etiology Therapeutics

simultaneous determination of vitexin-2"-O-glucoside,vitexin-2"-O-rhamnoside,rutin,vitexin,and hyperoside by HPLC

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Pharmaceutical Analysis 2011年第4期1卷 291-296页

作者： Chang-He wang yu-xuan wang Hai-Jing Liu Shaanxi Institute for Food and Drug Control Xi＇an 710061 China Shaanxi University of Chinese Medicine Xianyang 712046 China

A simple, precise, and rapid high-performance liquid chromatographic method was developed and validated for the simultaneous determination of vitexin-2＂-O-glucoside, vitexin-2＂-O-rhamnoside, rutin, vitexin, and hyperoside. The HPLC separation was performed using a Shim-pack VP-ODS C18 column （250 mm ~ 4.6 mm i.d., 5 ~tm） with the isocratic mobile phase consisting of tetrahydrofuran/ acetonitrile/0.05% phosphoric acid solution （20：3：77, v/v/v）, and the flow rate was set at 1.0 mL/min. UV detection was carried out at a wavelength of 360 nrn and the whole analysis took 25 min. The method was linear in the range of 4.12-206.00 μg/mL for vitexin-2＂-O-glucoside, 4.05-202.50 μg/mL for vitexin-2＂-O- rhanmoside, 1.64-82.00 pμg/mL for rutin, 1.74-87.00 gg/mL for vitexin, and 1.41-70.60 p.g/mL for hyperoside with the correlation coefficient for each analyte more than 0.998. The limit of detection （LOD） and limit of quantitation （LOQ） were 0.6 and 2 ng for vitexin-2＂-O-glucoside, 0.6 and 2 ng for vitexin-2＂-O-rhamnoside, 0.3 and 1 ng for rutin, 1 and 3 ng for vitexin, and 0.5 and 2 ng for hyperoside, respectively. Intra- and inter-day precision and accuracy （RSD） were less than 3%. The developed HPLC method was successfully applied to the analysis of five flavonoids in hawthorn leaves, hawthorn fruits, and the preparations containing hawthorn leaves or fruits.

关键词： High-performanceliquid chromatography Flavonoids Hawthorn Leaves and fruits Preparations

Observation of the density dependence of the closed-channel fraction of a 6Li superfluid

在线全文

学校读者我要写书评

暂无评论

National Science Review 2022年第10期9卷 105-111页

作者： Xiang-Pei Liu Xing-Can Yao Hao-Ze Chen Xiao-Qiong wang yu-xuan wang yu-Ao Chen Qijin Chen Kathryn Levin Jian-Wei Pan Hefei National Laboratory for Physical Sciences at the Microscale and Department of Modern Physics University of Science and Technology of China Shanghai Branch CAS Center for Excellence in Quantum Information and Quantum Physics University of Science and Technology of China Shanghai Research Center for Quantum Sciences James Franck Institute University of Chicago

Atomic Fermi gases provide an ideal platform for studying pairing and superfluid physics,using a Feshbach resonance between closed-channel molecular states and open-channel scattering *** particular interest is the strongly interacting *** show that the closed-channel fraction Zccprovides an effective probe for important many-body interacting effects,especially through its density dependence,which is absent from two-body theoretical *** we measure Zccas a function of interaction strength and the Fermi temperature TF in a trapped 6Li superfluid throughout the entire Bardeen-Cooper-Schrieffer-Bose-Einstein-condensate crossover,in quantitative agreement with theory when important thermal contributions outside the superfluid core are taken into *** from the deep-BEC regime,the fraction Zccis sensitive to *** particular,our data show Zcc∝TFαwith α=1/2at unitarity,in quantitative agreement with calculations of a two-channel pairing fluctuation theory,and a increases rapidly into the BCS regime,reflecting many-body interaction effects as predicted.

关键词： closed-channel fraction density dependence strongly interacting Fermi gas many-body effect

Association between maternal gestational diabetes and allergic diseases in offspring:a birth cohort study

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

World Journal of Pediatrics 2023年第10期19卷 972-982页

作者： yu-Jing Chen Li-Zi Lin Zhao-Yan Liu Xin wang Shamshad Karatela yu-xuan wang Shan-Shan Peng Bi-Bo Jiang Xiao-Xu Li Nan Liu Jin Jing Li Cai Department of Maternal and Child Health School of Public HealthSun Yat-Sen UniversityNo.74 Zhongshan Road 2Yuexiu DistrictGuangzhou 510080Guangdong ProvincePeople’s Republic of China Guangdong Provincial Engineering Technology Research Center of Environmental Pollution and Health Risk Assessment Department of Occupational and Environmental HealthSchool of Public HealthSun Yat-Sen UniversityGuangzhouPeople’s Republic of China Department of Nutrition School of Public HealthSun Yat-Sen UniversityGuangzhouPeople’s Republic of China Guangdong Provincial Key Laboratory of Food Nutrition and HealthSchool of Public HealthSun Yat-Sen UniversityGuangzhouPeople’s Republic of China Key Laboratory of Brain Cognition and Education SciencesMinistry of EducationGuangzhouChina Faculty of Health and Behavioural Sciences Pharmacy Australia Centre of ExcellenceUniversity of QueenslandWoolloongabbaQLDAustralia Global Health Research Center Duke Kunshan UniversityKunshanPeople’s Republic of China Department of Medical Statistics School of Public HealthSun Yat-Sen UniversityGuangzhouPeople’s Republic of China Institute for Brain Research and Rehabilitation South China Normal UniversityGuangzhouPeople’s Republic of China Institute of Tropical Health and Medicine(AITHM) James Cook UniversityTownsvilleQLDAustralia

Background Previous studies have linked gestational diabetes(GDM)with allergies in ***,the effect of specific glucose metabolism metrics was not well characterized,and the role of polyunsaturated fatty acids(PUFAs),a modifier of metabolism and the immune system,was *** aimed to investigate the association between maternal GDM and allergic diseases in children and the interaction between glucose metabolism and PUFAs on allergic *** This prospective cohort study included 706 mother–child dyads from Guangzhou,*** GDM was diagnosed via a 75-g oral glucose tolerance test(OGTT),and dietary PUFAs were assessed using a validated food frequency *** disease diagnoses and the age of onset were obtained from medical records of children within three years *** Approximately 19.4%of women had GDM,and 51.3%of children had any allergic *** was positively associated with any allergic diseases(hazard ratio[HR]1.40;95%confidence interval(CI)1.05–1.88)and eczema(HR 1.44;95%CI 1.02–1.97).A unit increase in OGTT after two hours(OGTT-2 h)glucose was associated with an 11%(95%CI 2%–21%)higher risk of any allergic diseases and a 17%(95%CI 1–36%)higher risk of food *** positive associations between OGTT-2 h glucose and any allergic diseases were strengthened with decreased dietary a-linolenic acid(ALA)and increased n-6 PUFAs,linoleic acid(LA),LA/ALA ratio,and n-6/n-3 PUFA *** Maternal GDM was adversely associated with early-life allergic diseases,especially *** were the first to identify OGTT-2 h glucose to be more sensitive in inducing allergy risk and that dietary PUFAs might modify the associations.

关键词： Allergic disease Cohort study Eczema Gestational diabetes Polyunsaturated fatty acid

Regulatory factors of Nrf2 in age-related macular degeneration pathogenesis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第7期17卷 1344-1362页

作者： Zi-Ling Hu yu-xuan wang Zi-yue Lin Wen-Shuo Ren Bo Liu Hui Zhao Qiong Qin Five Year Program of Ophthalmology and Optometry 2019 Beijing Tong Ren HospitalCapital Medical UniversityBeijing 100054China Four Year Program of Traditional Chinese Pharmacy 2020 School of Traditional Chinese MedicineCapital Medical UniversityBeijing 100069China School of Traditional Chinese Medicine Capital Medical UniversityBeijing 100069China Beijing Key Laboratory of TCM Collateral Disease Theory Research Beijing 100069China Five Year Program of Ophthalmology and Optometry 2021 School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China Biochemistry&Molecular Biology School of Basic Medical SciencesCapital Medical UniversityBeijing 100069China

Age-related macular degeneration(AMD)is a complicated disease that causes irreversible visual *** evidences pointed retinal pigment epithelia(RPE)cells as the decisive cell involved in the progress of AMD,and the function of anti-oxidant capacity of PRE plays a fundamental physiological *** factor erythroid 2 related factor 2(Nrf2)is a significant transcription factor in the cellular anti-oxidant system as it regulates the expression of multiple anti-oxidative *** functions of protecting RPE cells against oxidative stress(OS)and ensuing physiological changes,including inflammation,mitochondrial damage and autophagy dysregulation,have already been *** the roles of upstream regulators of Nrf2 could provide further insight to the OS-mediated AMD *** the first time,this review summarized the reported upstream regulators of Nrf2 in AMD pathogenesis,including proteins and miRNAs,and their underlying molecular mechanisms,which may help to find potential targets via regulating the Nrf2 pathway in the future research and further discuss the existing Nrf2 regulators proved to be beneficial in preventing AMD.

关键词： Nrf2 upstream regulators retinal pigment epithelia age-related macular degeneration oxidative stress

Evaluation and treatment of altered mental status patients in the emergency department:Life in the fast lane

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Emergency Medicine 2012年第4期3卷 270-277页

作者： Hai-yu Xiao yu-xuan wang Teng-da Xu Hua-dong Zhu Shu-bin Guo Zhong wang Xue-zhong yu Department ofMedicme Beijing Puren Hospital Beijing 100062 China Department of Behavioral Science andHealth Education Emory University Rollins School of Public Health Atlanta USA Department of Emergency Medicine Peking Union Medical College Hospital Chinese Academy of Medical Sciences Beijing 100730 China

BACKGROUND： Altered mental status （AMS） is a very common emergency case, but the exact etiology of many AMS patients is unknown. Patients often manifest vague symptoms, thus, AMS diagnosis and treatment are highly challenging for emergency physicians. The aim of this study is to provide a framework for the assessment of AMS patients. This assessment should allow providers to better understand the etiology of mental status changes and therefore improve diagnostic skills and ***： This is a prospective cohort observational study. We recruited all adult patients with undifferentiated AMS at a single center tertiary care academic emergency department over 24 months （June 2009 to June 2011）. Demographic characteristics, clinical manifestations, assessment approaches, causative factors, emergency treatments and outcomes were collected ***： In 1934 patients with AMS recruited, accounting for 0.93% of all emergency department （ED） patients, 1 026 （53.1%） were male, and 908 （46.9%） female. Their average age was 51.95±15.71 years. Etiologic factors were neurological （n=641; 35.0%）, pharmacological and toxicological （n=421; 23.0%）, systemic and organic （n=266; 14.5%）, infectious （n=167; 9.1%）, endocrine/metabolic （n=145; 7.9%）, psychiatric （n=71; 3.9%）, traumatic （n=38; 2.1%）, and gynecologic and obstetric （n=35; 1.9%）. Total mortality rate was 8.1% （n=156）. The death rate was higher in elderly patients （≥60） than in younger patients （10.8% vs. 6.9%, P=-0.003）.CONCLUSION： Patients with AMS pose a challenge for ED physicians. The most frequently encountered diagnostic categories causing AMS were primary CNS disorders, intoxication, organ system dysfunction, and endocrine/metabolic diseases. AMS has a high fatality rate in the ED. AMS is an important warning signal for ED patients because of its potentially fatal and reversible effects. Prompt evaluation and treatment are essential to decreasing morbidity and mortality associated with AMS.

关键词： Altered mental status Emergency department Demographic characteristics Clinical feature Assessment Etiology Mortality Algorithm

不同氧化程度的掺硼金刚石膜电极的电化学性能及电荷转移速率研究

在线全文

学校读者我要写书评

暂无评论

北京大学学报（自然科学版） 2016年第5期52卷 911-918页

作者：于鹏邢璇王婷北京大学深圳研究生院环境与能源学院深圳518055 北京大学环境工程系水沙科学教育部重点实验室北京100871 中央民族大学生命与环境学院北京100081

通过阳极电化学氧化法,制备不同氧化程度的掺硼金刚石膜(BDD)电极,并对其进行表征。分别采用循环伏安法和Mott-Schottky曲线,研究不同氧化程度的BDD电极的电化学性质和电荷转移速率。扫描电子显微镜和拉曼光谱分析表明,氧化后的BDD电极... 详细信息

通过阳极电化学氧化法,制备不同氧化程度的掺硼金刚石膜(BDD)电极,并对其进行表征。分别采用循环伏安法和Mott-Schottky曲线,研究不同氧化程度的BDD电极的电化学性质和电荷转移速率。扫描电子显微镜和拉曼光谱分析表明,氧化后的BDD电极形貌和晶型结构几乎未发生变化,但EDX能谱分析发现BDD表面氧含量明显增加。循环伏安法和Mott-Schottky曲线阳极电流法研究发现,电荷转移速率随氧化程度的增大而逐渐增大。接触角实验进一步证实,随着BDD电极氧化程度的增加,接触角减小,电极表面亲水性逐渐增大,因此以阳极电流方式表示的电荷转移速率增大。然而,Mott-Schottky曲线以氧化还原电位差方式表示的电荷转移速率随氧化程度的增大,先增大,后减小,这是由于在不同的氧化时间下,表面基团的种类及其各成分在总含氧量中所占比例不同,因此产生的电荷转移速率也不相同。

关键词：掺硼金刚石膜氧化程度电荷转移速率平带电压

Oscillatory-like expansion of a Fermionic superfluid

在线全文

学校读者我要写书评

暂无评论

Science Bulletin 2020年第1期65卷 7-11,M0003页

作者： Xiao-Qiong wang yu-Ping Wu Xiang-Pei Liu yu-xuan wang Hao-Ze Chen Mudassar Maraj Youjin Deng Xing-Can Yao yu-Ao Chen Jian-Wei Pan Shanghai Branch National Laboratory for Physical Sciences at Microscale and Department of Modem PhysicsUniversity of Science and Technology of ChinaShanghai 201315China CAS Center for Excellence and Synergetic Innovation Center in Quantum Information and Quantum Physics University of Science and Technology of ChinaHefei 230026China

We study the expansion behaviors of a Fermionic superfluid in a cigar-shaped optical dipole trap for the whole BEC-BCS crossover and various *** low temperature(0:06(1)T_F),the atom cloud undergoes an anisotropic hydrodynamic expansion over 30 ms,which behaves like oscillation in the horizontal *** analyzing the expansion dynamics according to the superfluid hydrodynamic equation,the effective polytropic index y of Equation-of-State(EoS)of Fermionic superfluid is *** y values show a non-monotonic behavior over the BEC-BCS crossover,and have a good agreement with the theoretical results in the unitarity and BEC *** normalized quasi-frequencies of the oscillatory expansion are measured,which drop significantly from the BEC side to the BCS side and reach a minimum value of 1.73 around 1/k_Fa=-0:*** work improves the understanding of the dynamic properties of strongly interacting Fermi gas.

关键词： Fermionic superfluid Oscillatory-like expansion BEC-BCS crossover Equation-of-State

在线全文

学校读者我要写书评

暂无评论

无阻尼弱耗散抽象发展方程的强全局吸引子

华东师范大学学报（自然科学版） 2017年第2期 8-19页

作者：张玉宝汪璇西北师范大学数学与统计学院兰州730070

运用半群理论、收缩函数理论和定义泛函的方法,当非线性项满足较弱的耗散型条件时,在空间V_(2θ)×V_θ×L_μ~2(R^+;V_(2θ))中得到了无阻尼弱耗散抽象发展方程的强全局吸引子的存在性.

关键词：抽象发展方程收缩函数全局吸引子