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Chinese Physics B 2016年第12期25卷 277-282页

作者：陆俊黄志远王丁许毅刘彦祺郭晓杨黎文开吴分翔刘征征冷雨欣 School of Physics Science and Engineering Tongji University Shanghai 200092 China State Key Laboratory of High Field Laser Physics Institute of Optics and Fine Mechanics Chinese Academy of Sciences Shanghai 201800 China University of Chinese Academy of Sciences Beijing 100049 China Department of Physics Shanghai University Shanghai 200444 China

We theoretically study the nonlinear compression of a 20-rnJ, 1030-nm picosecond chirped pulse from the thin-disk amplifier in a krypton gas-filled hollow-core fiber. The chirp from the thin-disk amplifier system has little influence on the initial pulse, however, it shows an effect on the nonlinear compression in hollow-core fiber. We use a large diameter hollow waveguide to restrict undesirable nonlinear effects such as ionization; on the other hand, we employ suitable gas pressure and fiber length to promise enough spectral broadening; with 600-μm, 6-bar （1 bar = 105 Pa）, 1.8-m hollow fiber, we obtain 31.5-fs pulse. Moreover, we calculate and discuss the optimal fiber lengths and gas pressures with different initial durations induced by different grating compression angles for reaching a given bandwidth. These results are meaningful for a compression scheme from picoseconds to femtoseconds.

关键词： picosecond pulse hollow-core fiber thin-disk amplifier spectrum broadening

Double Grating Expanders for Fourth-Order Dispersion Compensation in Chirped Pulse Amplifiers

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Chinese Physics Letters 2013年第4期30卷 99-101页

作者： WANG Cheng leng yu-xin State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800

A scheme of double grating expanders is first proposed for high energy chirped pulse *** is demonstrated that they can compensate for the amplifier's material dispersion up to the fourth-order,together with a suitable grating *** scheme makes it possible that the pulse expansion in Chirped pulse amplifiers(CPAs)is no longer restricted by the material dispersion,and the corresponding grating compressor can be independently optimized according to the available gratings'size and damage threshold.

关键词： amplifier compressor dispersion

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-yu Zhao Juan-Han yu Yi-Hua Wang Yi-xin Liu Lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Architecture,Key Technologies and Applications of Load Dispatching in China Power Grid

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Journal of Modern Power Systems and Clean Energy 2022年第2期10卷 316-327页

作者： yu Dong xin Shan Yaqin Yan Xiwu leng Yi Wang State Grid Corporation of China Beijing 100031China NARI Group Corporation(State Grid Electric Power Research Institute) Nanjing 211000China

With the development of renewable energy and the changes in the characteristics of power grid,it is becoming increasingly difficult to balance power supply and demand in space and *** addition,the requirement for improved dispatching capability of power grid is ***,the potential of flexible load dispatching should be realized,which can promote the large-scale consumption of renewable energy and the construction of new power *** on the analysis of existing load dispatching studies and the differences in the characteristics of domestic and foreign load dispatchings,a technical architecture and several key technologies are proposed for load resources to participate in power grid dispatching under the new situation,i.e.,the autonomous collaborative control system of load *** system implements the multi-layer coordinated control of main,distribution and micro grids(load aggregators).Adjustable load resources are aggregated through an aggregator operation platform and connected with a dispatcher load regulator platform to realize real-time data interaction with dispatching agencies as well as the monitoring,con-trol,and marketing of *** supports the load resources to participate in network-wide dispatching optimization via continuous power *** key technologies such as the control mode,load modeling,dispatching strategy,and safety protection are also *** the closed-loop control of orderly charging piles and energy storage clusters in the North China Power Grid,the feasibility of the proposed architecture and key technologies is *** route has successively supported multiple adjustable load aggregators to partici-pate in the ancillary services market of North China Power Grid for ***,the technical challenges of load resources participating in power grid dispatching under the dual carbon goals are discussed and prospected.

关键词： Automatic power control(APC) load modeling load dispatching renewable energy accommodation situation awareness.

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang Hui-Na Liu yu-Fan Yang Zhi-Cheng Zhang Qi Dai Xiao-Yan Bao Lin-Jie Wu Ya-xin Qin xin Tan Xiao-Yan Sun Xu-Fang Ying Zhi-Qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin

Plasmon-induced local electric field improved hydrogen evolution reaction on Ag/Mo_(2)C nanosheets

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Nano Research 2025年第1期18卷 270-277页

作者： HuangJingWei Li xin Zi Jun Wu xinli Wang Li Zhu Qiyou Wang Jianfu Han Junwei Fu Hongmei Li Kai Huang yu Chen Min Liu School of Physics State Key Laboratory of Powder MetallurgyHunan Joint International Research Center for Carbon Dioxide Resource UtilizationCentral South UniversityChangsha 410083China School of Metallurgy and Environment Central South UniversityChangsha 410083China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Nano-Institute Munich Faculty of PhysicsLudwig-Maxilimians-Universität MünchenMünchen 80539Germany Hunan Institute of Advanced Sensing and Information Technology Xiangtan UniversityXiangtan 411105China

Electrocatalytic water splitting offers a promising way for hydrogen production with near-zero ***,such as molybdenum carbides(Mo_(2)C),are promising materials for hydrogen evolution reaction(HER)but still suffer from poor intrinsic water activation ***,we developed a plasmon-induced local electric field(PILEF)strategy to solve this ***(Ag)nanoparticles decorated Mo_(2)C nanosheets(Ag/Mo_(2)C)were successfully prepared by electrostatic *** visible light excited the PILEF on Ag/Mo_(2)C remarkably reducing the activation energy by 92.7 kJ·mol^(-1)from 147.3 kJ·mol^(-1)of Mo_(2)C to 54.6 kJ·mol^(-1).As a result,the plasmonic Ag/Mo_(2)C significantly enhances~2.3-fold of the current density from 2.8 mA·cm^(-2)of Mo_(2)C to 6.5 mA·cm^(-2)at-3 V *** and reduces the overpotential by 104 mV from 403 mV of dark state to 299 mV of light state at the current density of 10 mA·cm^(-2),achieving better performance than reported *** research demonstrates that PILEF enhances HER activities,offering a potential strategy for boosting the intrinsic activities of catalysts.

关键词： sliver particles plasmon effect field effect hydrogen evolution reaction(HER) electrocatalysis

Sine oculis homeobox homolog family function in gastrointestinal cancer:Progression and comprehensive analysis

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World Journal of Clinical Oncology 2025年第1期16卷 10-24页

作者： Yang-Zheng Lan Zheng Wu Wen-Jia Chen xin-Ning yu Hua-Tao Wu Jing Liu Department of The Breast Center Cancer Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina Department of General Surgery First Affiliated Hospital of Shantou University Medical CollegeShantou 515041Guangdong ProvinceChina

The sine oculis homeobox homolog(SIX)family,a group of transcription factors characterized by a conserved DNA-binding homology domain,plays a critical role in orchestrating embryonic development and organogenesis across various organisms,including *** six distinct members,from SIX1 to SIX6,each member contributes uniquely to the development and differentiation of diverse tissues and organs,underscoring the versatility of the SIX *** or mutations in SIX genes have been implicated in a spectrum of developmental disorders,as well as in tumor initiation and progression,highlighting their pivotal role in maintaining normal developmental trajectories and cellular *** to target the transcriptional complex of the SIX gene family have emerged as a promising strategy to inhibit tumor *** the development of inhibitors targeting this gene family is still in its early stages,the significant potential of such interventions holds promise for future therapeutic ***,this review aimed to comprehensively explore the advancements in understanding the SIX family within gastrointestinal cancers,focusing on its critical role in normal organ development and its implications in gastrointestinal cancers,including gastric,pancreatic,colorectal cancer,and hepatocellular *** conclusion,this review deepened the understanding of the functional roles of the SIX family and explored the potential of utilizing this gene family for the diagnosis,prognosis,and treatment of gastrointestinal cancers.

关键词： Sine oculis homeobox homolog Gastrointestinal cancer Transcription factor Development Regulation Diagnosis Therapeutics

Selective Synthesis of Hexagonal Ag Nanoplates in a Solution-Phase Chemical Reduction Process

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Nano Research 2010年第12期3卷 843-851页

作者： Mingzhu Liu Mei leng Chao yu xin Wang Cheng Wang State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China Graduate School of the Chinese Academy of Sciences Beijing100049China Division of Chemical and Biomolecular Engineering Nanyang Technological University637722Singapore

Two-dimensional(2-D)Ag nanoplates have surface plasmon resonances which can be tuned from the visible to the near-IR by varying the size and morphology of the *** to their anisotropic structures and different surface energy distributions,Ag nanoplates-especially triangular ones-are kinetically stable and can transform into other *** advantage of the synergetic effects of HNO_(3)and Cl-in the reduction solution,uniform Ag hexagonal nanoplates(HNPs)have been captured during the transformation of Ag triangular nanoplates(TNPs).The dimensions of the Ag HNPs can be controlled by changing the concentrations of reagents in the reaction or/and reduction *** absorption spectra of the obtained Ag HNPs indicated that their in-plane resonance peaks could be tuned from the visible to the near-IR region,showing their potential applications in medical diagnosis.

关键词： Synthesis Ag hexagonal nanoplates etching effect transformation

Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu yu Li-yun Zhou Xiao Huang xin-yue Li Ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

Broadening and Amplification of an Infrared Femtosecond Pulse for Optical Parametric Chirped-Pulse Amplification

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Chinese Physics Letters 2011年第10期28卷 99-102页

作者： WANG He-Lin YANG Ai-Jun leng yu-xin College of Science Zhejiang University of TechnologyHangzhou 310023 State Key Laboratory of High Field Laser Physics Shanghai Institute of Optics and Fine MechanicsChinese Academy of SciencesShanghai 201800

A high-average-power diode-pumped narrowband regenerative chirped pulse amplifier is developed using the thin-rod Nd:YAG laser architecture for optical parametric chirped-pulse amplification(OPCPA).The effect of the etalons on the amplified pulse in the regenerative cavity is studied experimentally and *** inserting glass etalons of thickness 1 mm and 5 mm into the regenerative cavity,the pre-stretching pulse from anÖffner stretcher is further broadened to above 200 ps,which matches the amplification windows of the signal pulses in OPCPA and is suitable for use as a pump source in the OPCPA *** bandwidth of the amplified pulse is 1.5 nm,and an output energy of 2 mJ is achieved at a repetition rate of 10 Hz.

关键词： Nd:YAG Pulse cavity