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High mortality associated with gram-negative bacterial bloodstream infection in liver transplant recipients undergoing immunosuppression reduction

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World Journal of Gastroenterology 2020年第45期26卷 7191-7203页

作者： Fang Chen xiao-yun Pang Chuan Shen Long-Zhi Han yu-xiao deng xiao-Song Chen Jian-Jun Zhang Qiang Xia Yong-Bing Qian Department of Pharmacy Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200127China Department of Liver Surgery Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200127China Department of Critical Care Medicine Renji HospitalSchool of MedicineShanghai Jiaotong UniversityShanghai 200127China

BACKGROUND Immunosuppression is an important factor in the incidence of infections in transplant *** studies are available on the management of immunosuppression(IS)treatment in the liver transplant(LT)recipients complicated with *** aim of this study is to describe our experience in the management of IS treatment during bacterial bloodstream infection(BSI)in LT recipients and assess the effect of temporary IS withdrawal on 30 d mortality of recipients presenting with severe *** To assess the effect of temporary IS withdrawal on 30 d mortality of LT recipients presenting with severe *** A retrospective study was conducted with patients diagnosed with BSI after LT in the Department of Liver Surgery,Renji Hospital from January 1,2016 through December 31,*** recipients diagnosed with BSI after LT were *** and multivariate Cox regression analysis of risk factors for 30 d mortality was conducted in the LT recipients with Gram-negative bacterial(GNB)*** Seventy-four episodes of BSI were identified in 70 LT recipients,including 45 episodes of Gram-positive bacterial(GPB)infections in 42 patients and 29 episodes of GNB infections in 28 ***,IS reduction(at least 50%dose reduction or cessation of one or more immunosuppressive agent)was made in 28(41.2%)cases,specifically,in 5(11.9%)cases with GPB infections and 23(82.1%)cases with GNB *** 180 d all-cause mortality rate was 18.5%(13/70).The mortality rate in GNB group(39.3%,11/28)was significantly higher than that in GPB group(4.8%,2/42)(P=0.001).All the deaths in GNB group were attributed to worsening infection secondary to IS withdrawal,but the deaths in GPB group were all due to graft-versus-host *** group was associated with significantly higher incidence of intra-abdominal infection,IS reduction,and complete IS withdrawal than GPB group(P<0.05).Cox regression showed that rejection(adjusted hazard ratio 7.021,P=0.

关键词： Immunosuppressive therapy Liver transplantation Bloodstream infection Multidrug-resistant gram-negative bacterium

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Gene locations may contribute to predicting gene regulatory relationships

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Journal of Zhejiang University-Science B(Biomedicine & Biotechnology) 2018年第1期19卷 25-37页

作者： Jun MENG Wen-yuan XU xiao CHEN Tao LIN xiao-yu deng Department of System Science and Engineering School of Electrical Engineering Zhejiang University Laboratory of Machine Learning and Optimization école Polytechnique Fédérale de Lausanne (EPFL)

We propose that locations of genes on chromosomes can contribute to the prediction of gene regulatory relationships. We constructed a time-based gene regulatory network of zebrafish cardiogenesis on the basis of a spatio-temporal neighborhood method. Through the network, specific regulatory pathways and order of gene expression during zebrafish cardiogenesis were obtained. By comparing the order with locations of these genes on chromosomes, we discovered that there exists a reversal phenomenon between the order and order of gene locations. The discovery provides an inherent rule to instruct exploration of gene regulatory relationships. Specifically, the discovery can help to predict if regulatory relationships between genes exist and contribute to evaluating the correctness of discovered gene regulatory relationships.

关键词： Prediction Gene regulatory relationships Order of gene location Spatio-temporal neighborhood method Zebrafish cardiogenesis

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Three-dimensional Printed Patient-specific Drilling Templates for Expansive Open-door Laminoplasty

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Chinese Medical Journal 2016年第21期129卷 2644-2646页

作者： Xin Rong Bei-yu Wang yu-xiao deng Hao Liu Department of Orthopedic Surgery West China Hospital Sichuan University Chengdu Sichuan 610041 China

The expansive open-door laminoplasty （EOLP） has been proven effective in treating patients with cervical myelopathy caused by bony cervical stenosis or ossification of the posterior longitudinal ligament. The aim of... 详细信息

关键词： Cervical Spine Computer-aided Design Laminoplasty Rapid Prototyping Template

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多时段露天矿生产计划整体优化模型

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东北大学学报（自然科学版） 2016年第10期37卷 1460-1464页

作者：孙效玉邓鹏宏赵明东北大学资源与土木工程学院辽宁沈阳110819 鞍钢矿业公司决策支持部辽宁鞍山114004 中煤科工集团沈阳设计研究院有限公司露天工程事业部辽宁沈阳110015

针对数学优化方法在露天矿进度计划应用中存在的只对单一时段计划进行优化,或是对多时段计划进行分段优化,没有实现全时段整体优化的问题,在前后时段0-1整数规划和大小时段0-1整数规划两种模型分段优化的前期工作基础上,提出了露天矿整... 详细信息

针对数学优化方法在露天矿进度计划应用中存在的只对单一时段计划进行优化,或是对多时段计划进行分段优化,没有实现全时段整体优化的问题,在前后时段0-1整数规划和大小时段0-1整数规划两种模型分段优化的前期工作基础上,提出了露天矿整体优化的0-1整数规划模型,并针对计算速度慢的问题,提出了相应的改进措施.该模型既实现了多时段生产计划的整体优化,又解决了分段优化无解的隐患,还保证了速度和精度,不仅可实现用下层计划验证上层计划,而且可用于由下层计划导出上层计划,其实用性和通用性更好.

关键词：露天矿生产进度计划 0-1整数规划线性规划整体优化多时段

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Smart Cellulose‑Based Janus Fabrics with Switchable Liquid Transportation for Personal Moisture and Thermal Management

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Nano-Micro Letters 2025年第1期17卷 333-347页

作者： Jianfeng Xi Yanling Lou Liucheng Meng Chao deng Youlu Chu Zhaoyang Xu Huining xiao Weibing Wu Jiangsu Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources International Innovation Center for Forest Chemicals and MaterialsJiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass MaterialsNanjing Forestry UniversityNanjing 210037People’s Republic of China College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering University of New BrunswickFrederictonNB E3B 5A3Canada Macromolecular Chemistry and Bavarian Polymer Institute University of BayreuthBayreuth 95440Germany

The Janus fabrics designed for personal moisture/thermal regulation have garnered significant attention for their potential to enhance human ***,the development of smart and dynamic fabrics capable of managing personal moisture/thermal comfort in response to changing external environments remains a ***,a smart cellulose-based Janus fabric was designed to dynamically manage personal moisture/*** cotton fabric was grafted with N-isopropylacrylamide to construct a temperature-stimulated transport ***,hydrophobic ethyl cellulose and hydrophilic cellulose nanofiber were sprayed on the bottom and top sides of the fabric to obtain wettability *** fabric exhibits anti-gravity directional liquid transportation from hydrophobic side to hydrophilic side,and can dynamically and continuously control the transportation time in a wide range of 3–66 s as the temperature increases from 10 to 40℃.This smart fabric can quickly dissipate heat at high temperatures,while at low temperatures,it can slow down the heat dissipation rate and prevent the human from becoming too *** addition,the fabric has UV shielding and photodynamic antibacterial properties through depositing graphitic carbon nitride nanosheets on the hydrophilic *** smart fabric offers an innovative approach to maximizing personal comfort in environments with significant temperature variations.

关键词： Directional water transport Cotton fabric Anti-gravity directional liquid transportation Janus wettability

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Graphene Aerogel Composites with Self‑Organized Nanowires‑Packed Honeycomb Structure for Highly Efficient Electromagnetic Wave Absorption

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Nano-Micro Letters 2025年第2期17卷 533-547页

作者： xiao You Huiying Ouyang Ruixiang deng Qiuqi Zhang Zhenzhong Xing xiaowu Chen Qingliang Shan Jinshan Yang Shaoming Dong State Key Laboratory of High Performance Ceramics and Superfine Microstructure Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Key Laboratory of Inorganic Coating Materials CAS Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Structural Ceramics and Composites Engineering Research Center Shanghai Institute of CeramicsChinese Academy of SciencesShanghai 200050People’s Republic of China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049People’s Republic of China School of Physical Science and Technology ShanghaiTech UniversityShanghai 201210People’s Republic of China School of Materials Science and Engineering Zhejiang Sci-Tech UniversityHangzhou 310018People’s Republic of China University of Chinese Academy of Sciences Beijing 100039People’s Republic of China

With vigorous developments in nanotechnology,the elaborate regulation of microstructure shows attractive potential in the design of electromagnetic wave ***,a hierarchical porous structure and composite heterogeneous interface are constructed successfully to optimize the electromagnetic loss *** macro–micro-synergistic graphene aerogel formed by the ice template‑assisted 3D printing strategy is cut by silicon carbide nanowires(SiC_(nws))grown in situ,while boron nitride(BN)interfacial structure is introduced on graphene *** unique composite structure forces multiple scattering of incident EMWs,ensuring the combined effects of interfacial polarization,conduction networks,and magnetic-dielectric ***,the as-prepared composites present a minimum reflection loss value of−37.8 dB and a wide effective absorption bandwidth(EAB)of 9.2 GHz(from 8.8 to 18.0 GHz)at 2.5 ***,relying on the intrinsic high-temperature resistance of SiC_(nws) and BN,the EAB also remains above 5.0 GHz after annealing in air environment at 600℃ for 10 h.

关键词： Hierarchical porous structure Interface High-temperature resistance Graphene aerogel composites Electromagnetic wave absorption

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Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao yu-Gui Peng Peng Wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

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Experimental Observing Damage Evolution in Cement Pastes Exposed to External Sulfate Attack by in situ X-ray Computed Tomography

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 164-170页

作者： WU Min CAO Kailei xiao Weirong yu Zetai CAO Jierong DING Qingjun LI Jinhui China Railway Construction Corporation Harbour and Channel Engineering Bureau Group Co. LTDZhuhai 519000China Con-struction Headquarters of Zhoushan Liuheng Bridge Phase II Project Zhoushan 316000China China Railway Construction Bridge En-gineering Bureau Group Co. LTDTianjin 300000China State Key Laboratory of Silicate Material for Architecture(Wuhan University of Technology) Wuhan 430070China College of Materials Science and Engineering Wuhan Textile UniversityWuhan 430200China

The paper presents experimental investigation results of crack pattern change in cement pastes caused by external sulfate attack(ESA).To visualize the formation and development of cracks in cement pastes under ESA,an X-ray computed tomography(X-ray CT)was used,i e,the tomography system of Zeiss Xradia 510 *** results indicate that X-CT can monitor the development process and distribution characteristics of the internal cracks of cement pastes under ESA with attack *** addition,the C3A content in the cement significantly affects the damage mode of cement paste specimens during sulfate *** damage of ordinary Portland cement(OPC)pastes subjected to sulfate attack with high C3A content are severe,while the damage of sulfate resistant Portland cement(SRPC)pastes is much smaller than that of OPC ***,a quadratic function describes the correlation between the crack volume fraction and development depth for two cement pastes immermed in sulfate solution.

关键词： concrete external sulfate attack damage evolution situ X-ray computed tomography

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多种有序钙钛矿结构的高压制备与特殊物性

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物理学报 2017年第3期66卷 1-22页

作者：殷云宇王潇邓宏芟周龙戴建洪龙有文中国科学院物理研究所北京凝聚态物理国家实验室(筹)北京100190 量子物质科学协同创新中心北京100190

具有ABO_3钙钛矿或类似结构的强关联电子体系是凝聚态物理研究的重要前沿领域,而高压是制备新型钙钛矿特别是A位与/或B位有序钙钛矿材料的有效手段.在这些有序钙钛矿中,因A,B位可同时容纳过渡金属离子,因而可导致A-A,B-B,A-B等多种磁电... 详细信息

具有ABO_3钙钛矿或类似结构的强关联电子体系是凝聚态物理研究的重要前沿领域,而高压是制备新型钙钛矿特别是A位与/或B位有序钙钛矿材料的有效手段.在这些有序钙钛矿中,因A,B位可同时容纳过渡金属离子,因而可导致A-A,B-B,A-B等多种磁电相互作用的出现,进而诱导系列新颖有趣的物理现象.本文介绍高压下制备的几种化学式为AA'_3B_4O_(12)的新型A位有序钙钛矿以及化学式为AA'_3B_2B'_2O_(12)的A,B位同时有序的钙钛矿体系.在LaMn_3Cr_4O_(12)中发现了具有立方钙钛矿结构的磁电多铁性,为多铁新材料探索与新机理研究提供范例;在CaCu_3Fe_2Os_2O_(12)中发现了远高于室温的亚铁磁半导体行为,并指出A位磁性离子的引入可大大增加磁相互作用强度从而大幅度提高磁有序温度;在LaMn_3Ni_2Mn_2O_(12)中观察到A位磁性离子调控的B位Ni^(2+)/Mn^(4+)子晶格正交自旋有序结构.以上研究结果为探索新型磁电多功能钙钛矿材料提供了重要参考.

关键词：高压合成有序钙钛矿多铁性自旋有序

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The Microbial Change Trend Relevant to Panax notoginseng Root Rot Diseases

The Microbial Change Trend Relevant to Panax notoginseng Roo...

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第十四届全国中药和天然药物学术研讨会

作者： Jun Xie Meng-yue Zhang Tian-yuan Zhang Huan Xu Xue-Song Xiang xiao-yu deng Jin-yu Zhang yung-Chi Cheng Yi-Xuan Zhang Shenyang Pharmaceutical University Institute of Medicinal Plants in yunnan Academy of Agricultural Sciences Yale University School of Medicine

＜正＞The variations of microbes associated with Panax notoginseng root rot diseases have not been *** this study,27 notoginseng rhizosphere soil samples were collected from 3farms of Wenshan,yunnan *** soil samples included soils before notoginseng cultivation;1,2,3 years during cultivation and 1 year after crop rotation.18 plant samples

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