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Preoperative serum cortisone levels are associated with cognition in preschool‑aged children with tetralogy of Fallot after corrective surgery:new evidence from human populations and mice

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World Journal of Pediatrics 2024年第2期20卷 173-184页

作者： Si-yu Ma yu-Ting Liu yue-Shuang Cun Qiang Wang Ming-cui Fu Ke-De Wu Xin-yu Cai Shu-Ting Cheng Nishant Patel Min Da Liang Hu Zhuoga Deqin Xue-jun Kang Ming Yang Xu-Ming Mo Department of Cardiothoracic Surgery Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Department of Radiology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Key Laboratory of Child Development and Learning Science Research Center For Learning ScienceSchool of Biological Sciences&Medical EngineeringMinistry of EducationSoutheast UniversityNanjing 210096China Medical School of Nanjing University Nanjing 210093China

Background Tetralogy of Fallot(TOF)is the most common cyanotic congenital heart *** with TOF would be confronted with neurological impairment across their *** study aimed to identify the risk factors for cerebral morphology changes and cognition in postoperative preschool-aged children with *** We used mass spectrometry(MS)technology to assess the levels of serum metabolites,Wechsler preschool and primary scale of intelligence-Fourth edition(WPPSI-Ⅳ)index scores to evaluate neurodevelopmental levels and multimodal magnetic resonance imaging(MRI)to detect cortical morphological *** Multiple linear regression showed that preoperative levels of serum cortisone were positively correlated with the gyrification index of the left inferior parietal gyrus in children with TOF and negatively related to their lower visual spaces index and nonverbal ***,preoperative SpO_(2) was negatively correlated with levels of serum cortisone after adjusting for all ***,after intervening levels of cortisone in chronic hypoxic model mice,total brain volumes were reduced at both postnatal(P)11.5 and P30 *** Our results suggest that preoperative serum cortisone levels could be used as a biomarker of neurodevelopmental impairment in children with *** study findings emphasized that preoperative levels of cortisone could influence cerebral development and cognition abilities in children with TOF.

关键词： Cognition Cortisone MRI Neurodevelopment Tetralogy of Fallot

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Synthesis,Structure and Chemical Bonding of Polyantimony Clusters Containing Coinage Metals[M_(2)Sb_(14)]^(4-)(M=Cu,Ag)

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Chinese Journal of Chemistry 2024年第6期42卷 617-622页

作者： Wei-Xing Chen yu-He Xu cui-cui Wang Lei Qiao Zi-Yan Guo Wen-Juan Tian Zhong-Ming Sun State Key Laboratory of Element-Organic Chemistry Tianjin Key Lab for Rare Earth Materials and ApplicationsSchool of Materials Science and EngineeringNankai UniversityTianjin300350 China Institute of Molecular Science Shanxi UniversityTaiyuanShanxi030006 China

Binary polyantimony clusters,namely[Cu_(2)Sb_(14)]^(4–) and [Ag_(2)Sb_(14)]^(4–),containing coinage metals,were successfully synthesized and characterized,in which two homoatomic Sb73–subunits are bridged by two coinage metals in η^(4):η^(1) and η^(1):η^(1) coordination modes,***[M_(2)Sb_(14)]^(4-),two bridging Cu ions and two Sb atoms form a planar rhombic unit,which was revealed to have antiaromatic properties by theoretical *** electron structure and bonding analysis confirmed the presence of delocalized bonds in the rhombic unit and the metallophilic interaction between two formal M^(+) ions.

关键词： Polyantimony cluster Copper Silver Antiaromaticity Metallophilic interaction Quantum chemical calculations

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Solid solution strategy modulated defects engineering of(Cr_(1-x)V_(x))_(2)AlC MAX phase toward superior electromagnetic wave absorption

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Rare Metals 2024年第7期43卷 3205-3219页

作者： Ji-Lin Gou yu-Kai Chang Shu Liu Peng-Hui Li Ping-Hao cui Qian-Ku Hu Li-Bo Wang Xin Zhang jun-Kai Wang Qi-Xun Xia Ai-Guo Zhou School of Materials Science and Engineering Henan Polytechnic UniversityJiaozuo 454003China Key Laboratory for Microstructural Material Physics of Hebei Province School of ScienceYanshan UniversityQinhuangdao 066004China State Key Laboratory of Metastable Materials Science and Technology Yanshan UniversityQinhuangdao 066004China

Defects engineering is an effective strategy for manipulating electromagnetic parameters and enhancing electromagnetic wave(EMW)absorption ***,the relationship between them is not clear,especially in solid solution *** this work,a series of(Cr_(1-x)V_(x))_(2)AlC MAX phase solid solutions with layered structure were prepared via tuning the ratio of Cr and V to explore their EMW absorption *** experimental results indicated that the doping of V atoms at the M-site could effectively regulate its impedance matching and EMW absorption properties by introducing appropriate numbers of defects in the crystal,such as twin boundaries,dislocations and lattice *** them,if Cr:V=3:1,Cr_(1.5)V_(0.5)AlC,as radar absorption materials,could reach a strong reflection loss of-51.8 dB at the frequency of 12.8 GHz under an ultra-thin thickness of 1.3 *** reflection loss value could attain-10 dB in a wide frequency range of 2.7-18 GHz and thickness range of 1-5 *** addition,after high temperature and acid-alkali immersion treatment,this sample still had good EMW absorption capability,and the effective absorption bandwidth was enhanced from 2.3 to 2.6 GHz after concentrated acid immersion or 3.1 GHz after concentrated alkali *** work has great reference significance for the research and development of high-performance MAX-based EMW absorption materials in harsh environments.

关键词： MAX phases Solid solution Defects engineering Electromagnetic wave absorption Harsh environments

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Infection and Genomic Characteristics of Campylobacter jejuni from a Patient Without Diarrhea—China,2018

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China CDC weekly 2024年第33期6卷 846-851,I0001-I0005页

作者： Xiangdong Yang Wen Wang Chajin cui Binbin yu Qing Zhang Yanhua Wang Ecological Medicine Research Center National Key Laboratory of Intelligent Tracking and Forecasting for Infectious DiseasesNational Institute for Communicable Disease Control and PreventionChinese Center for Disease Control and PreventionBeijingChina Department of Zoonotic Disease Control and Prevention Yunnan Institute of Endemic Diseases Control&PreventionDali Bai Autonomous PrefectureYunnan ProvinceChina Medical Laboratory Department Yunnan Luxi County People’s HospitalHonghe Hani-Yi Autonomous PrefectureYunnan ProvinceChina

What is already known about this topic?A 20-month-old boy was admitted to the hospital with a maximum temperature of 40°C and a single ***,blood culture detected Francisella tularensis(***)using the VITEK 2 Compact *** is added by this report?After incubation of the patient’s blood for 48 hours,the cultured strain was identified as Campylobacter jejuni,named L8,excluding *** the genome sequence of L8,we found a novel Type VI Secretion System(T6SS),of which the conserved C-terminal VgrG domain from positions 561 to 884 showed significant *** are the implications for public health practice?It should be underscored that relying solely on automatic bacterial identification instruments for accurate strain identification is ***,our study suggests that the potential effect of T6SS should be considered when studying the genetic features of a patient’s clinical phenotypes.

关键词： Campylobacter admitted culture

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Bile acids,gut microbiota,and therapeutic insights in hepatocellular carcinoma

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Cancer Biology & Medicine 2024年第2期21卷 144-162页

作者： Yang Song Harry CH Lau Xiang Zhang jun yu Institute of Digestive Disease and Department of Medicine and Therapeutics State Key Laboratory of Digestive DiseaseLi Ka Shing Institute of Health SciencesCUHK Shenzhen Research InstituteThe Chinese University of Hong KongHong KongChina Department of Gastroenterology Zhongshan Hospital Xiamen UniversityXiamen 361004China

Hepatocellular carcinoma(HCC)is a prevalent and aggressive liver *** interplay between bile acids(BAs)and the gut microbiota has emerged as a critical factor in HCC development and *** normal conditions,BA metabolism is tightly regulated through a bidirectional interplay between gut microorganisms and *** gut microbiota plays a critical role in BA metabolism,and BAs are endogenous signaling molecules that help maintain liver and intestinal *** note,dysbiotic changes in the gut microbiota during pathogenesis and cancer development can disrupt BA homeostasis,thereby leading to liver inflammation and fibrosis,and ultimately contributing to HCC ***,understanding the intricate interplay between BAs and the gut microbiota is crucial for elucidating the mechanisms underlying *** this review,we comprehensively explore the roles and functions of BA metabolism,with a focus on the interactions between BAs and gut microorganisms in ***,therapeutic strategies targeting BA metabolism and the gut microbiota are discussed,including the use of BA agonists/antagonists,probiotic/prebiotic and dietary interventions,fecal microbiota transplantation,and engineered *** summary,understanding the complex BA-microbiota crosstalk can provide valuable insights into HCC development and facilitate the development of innovative therapeutic approaches for liver malignancy.

关键词： Bile acid gut microbiota hepatocellular carcinoma therapeutics microbiota modulation

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Spatially explicit reconstruction of cropland cover in Europe from AD 1800 to 2000

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Science China Earth Sciences 2024年第9期67卷 2953-2971页

作者： jun LI yu YE Xiuqi FANG Diyang ZHANG Zhilei WU Faculty of Geographical Science Beijing Normal UniversityBeijing 100875China Key Laboratory of Environmental Change and Natural Disaster Ministry of EducationBeijing Normal UniversityBeijing 100875China College of Geographical Science Qinghai Normal UniversityXining 810016China

One of the challenges in global change research is the significant uncertainty in global historical land use and land cover(LUCC)datasets,which are widely used as foundational *** addition to the regional cropland area reconstructions,improving the grid allocation method is another feasible way to raise the reliability of historical LUCC *** this study,an integrated reconstruction of the national cropland areas over the past 200 years was developed for 36 European *** that,the allocation algorithm was built using physiogeographic variables and historical city sites for accounting for land suitability and cultivation preferences,***,cropland data in Europe with a spatial resolution of 5′×5′at five time sections from AD 1800 to 2000 were generated using the optimal allocation algorithm in accordance with the stages of the regional *** results were as follows:(1)The dominant factors governing the distribution of croplands in Europe vary at different agricultural stages,but the results can be merged *** suitability was more optimal for allocation during the modern agricultural stage(AD 1950 and 2000);the priority index combined with land suitability and cultivation preference was more reasonable for allocation during the traditional agricultural stage(AD 1800).The average of the allocations by priority index and the land suitability could be adopted as the allocation results during the transitional stage(AD 1850 and 1900)because the grids for absolute differences within±10 and±20 percentage points between the results obtained from the above two allocations were above 80% and 95%,respectively,which means the two allocation results could be merged.(2)Over the past 200 years,the total cropland area in Europe first increased to a peak in AD 1900 and then ***,the centre of the higher cropland fraction shifted from the western part of Europe in AD 1800 to the eastern part of the continent after AD 1950.(3)

关键词： Land use and land cover change Historical cropland Gridding allocation Europe Past 200 years

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Desired Dynamic Equation for Primary Frequency Modulation Control of Gas Turbines

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Energy Engineering 2024年第5期121卷 1347-1361页

作者： Aimin Gao Xiaobo cui Guoqiang yu Jianjun Shu Tianhai Zhang Thermal Power Center Jiangsu Frontier Electric Technology Co.Ltd.Nanjing211102China School of Energy and Power Engineering Nanjing Institute of TechnologyNanjing211167China

Gas turbines play core roles in clean energy supply and the construction of comprehensive energy *** control performance of primary frequency modulation of gas turbines has a great impact on the frequency control of the power ***,there are some control difficulties in the primary frequency modulation control of gas turbines,such as the coupling effect of the fuel control loop and speed control loop,slow tracking speed,and so *** relieve the abovementioned difficulties,a control strategy based on the desired dynamic equation proportional integral(DDE-PI)is proposed in this *** on the parameter stability region,a parameter tuning procedure is *** is carried out to address the ease of use and simplicity of the proposed tuning ***,DDE-PI is applied to the primary frequency modulation system of an MS6001B heavy-duty gas *** simulation results indicate that the gas turbine with the proposed strategy can obtain the best control performance with a strong ability to deal with system *** proposed method shows good engineering application potential.

关键词： Gas turbine primary frequency modulation(PFM) desired dynamic equation(DDE) proportion-integral(PI)

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Extracorporeal shock wave therapy in treating ischial non-union following Bernese periacetabular osteotomy:A case report

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World Journal of Orthopedics 2024年第10期15卷 991-996页

作者： jun Yan jun-yu Zhu Fei-Fei Zhao Jian Xiao Hao Li Ming-Xin Wang Jing Guo Liang cui Geng-Yan Xing Department of Orthopedics The Third Medical Center of Chinese People's Liberation Army General HospitalBeijing 100039China Department of Orthopaedic Anhui Medical UniversityHefei 230032Anhui ProvinceChina Department of Orthopedics The Fourth Hospital of Hebei Medical UniversityShijiazhuang 050011Hebei ProvinceChina Department of Orthopedics The Fourth Medical Center of Chinese People’s Liberation Army General HospitalBeijing 100039China Department of Orthopaedic The Third Medical Center of Chinese People’s Liberation Army General HospitalThe Armed Police Clinical CollegeAnhui Medical UniversityHefei 230022Anhui ProvinceChina

BACKGROUND Extracorporeal shock wave therapy(ESWT)is increasingly being recognized as an advantageous alternative for treating non-union due to its efficacy and minimal associated ***-union following Bernese periacetabular osteotomy(PAO)is particularly challenging,with a reported 55%delayed union and 8%***,we highlight a unique case of ischial non-union post-PAO treated successfully with a structured ESWT *** SUMMARY A 50-year-old patient,diagnosed with left ischial non-union following the PAO,underwent six cycles of ESWT treatment across ten *** cycle,spaced four weeks apart,consisted of five consecutive ESWT sessions without *** X-ray follow-ups showed progressive disappearance of the fracture line and fracture *** patient ultimately achieved a satisfactory asymptomatic recovery and bone *** The results from this case suggest that this ESWT regimen can be a promising non-invasive treatment strategy for non-union following PAO.

关键词： Ischial non-union Extracorporeal shock wave therapy Non-union Bernese periacetabular osteotomy Case report

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αDecay in extreme laser fields within a deformed Gamow-like model

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Nuclear Science and Techniques 2024年第2期35卷 131-144页

作者： Qiong Xiao jun-Hao Cheng Yang-Yang Xu You-Tian Zou jun-Gang Deng Tong-Pu yu Department of Physics National University of Defense TechnologyChangsha 410073China College of Science China Three Gorges UniversityYichang 443002China

In this study, the effect of extreme laser fields on the α decay process of ground-state even–even nuclei was *** the deformed Gamow-like model, we found that state-of-the-art lasers can cause a slight change in the α decay penetration probability of most nuclei. In addition, we studied the correlation between the rate of change of the α decay penetration probability and angle between the directions of the laser electric field and α particle emission for different nuclei. Based on this correlation, the average effect of extreme laser fields on the half-life of many nuclei with arbitrary α particle emission angles was calculated. The calculations show that the laser suppression and promotion effects on the α decay penetration probability of the nuclei population with completely random α particle-emission directions are not completely *** remainder led to a change in the average penetration probability of the nuclei. Furthermore, the possibility of achieving a higher average rate of change by altering the spatial shape of the laser is explored. We conclude that circularly polarized lasers may be helpful in future experiments to achieve a more significant average rate of change of the α decay half-life of the nuclei population.

关键词： αDecay Deformed Gamow-like model Half-lives Extreme laser field Penetration probability

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Investigation of Ce/BEA as a passive NO_(x)adsorber:*** occurrences of cerium and adsorption behavior

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Journal of Rare Earths 2024年第7期42卷 1265-1271,I0003页

作者： Minghui yu Yiying Ding Xiaojie yu Siwei Yan Meiqing Shen Jianqiang Wang jun Wang Gurong Shen School of Materials Science and Engineering Tianjin UniversityTianjin300350China School of Chemical Engineering and Technology Tianjin UniversityTianjin300350China National Rare Earth Catalysis Research Institute Dongying257000China

Ce/BEA has great potential as a passive NO_(x)absorber(PNA)to reduce the NO_(x)emissions during the cold start phase especially in diesel engine for its high resistance to CO and suitable NO_(x)desorption temperature ***,as a novel material,its physical and chemical properties still remain *** this work,Ce/BEA was synthesized by ion-exchange method to identify the active species in NO_(x)adsorption,compared with aggregated Ce species in Ce/SiAlO_(x) prepared by impregnation method.X-ray diffraction(XRD),high resolution-transmission electron microscopy(HR-TEM)and aberration-corrected-scanning transmission electron microscopy(AC-STEM)were performed to confirm the isolated single atom formation of Ce species in Ce/***-vis diffraction reflection spectra(DRS)and X-ray photoelectron spectroscopy(XPS)were conducted to find the difference of chemical environment between the isolated Ce species and aggregated *** performance evaluation and temperature programmed reduction of hydrogen(H_(2)-TPR)results show the high NO_(x)storage capacity and active oxygen species quantity in Ce/*** is also found that the main NO_(x)adsorption species are Ce^(4+)-O^(∗)rather than Ce^(3+).NO_(x)-diffuse reflectance infrared Fourier transform spectroscopy(NO_(x)-DRIFTS)confirms that the bidentate nitrite species are the critical NO_(x)adsorption intermediates and the conception of NO_(x)adsorption and desorption processes is proposed.

关键词： Passive NO_(x)absorber Ce/BEA Isolated Ce species Rare earths

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