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Surgical treatment of liver cancer and pancreatic cancer under the China Healthcare Security Diagnosis Related Groups payment system

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World Journal of Clinical Cases 2024年第21期12卷 4673-4679页

作者： yun-He Hu Fan yu yu-zhuo zhou Ai-Dong Li National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100021China

BACKGROUND Data from the World Health Organization’s International Agency for Research on Cancer reported that China had the highest prevalence of cancer and cancer deaths in *** and pancreatic cancers accounted for the highest number of new ***-world data(RWD)is now widely preferred to traditional clinical trials in various fields of medicine and healthcare,as the traditional research approach often involves highly selected populations and interventions and controls that are strictly ***,research results from the RWD match global reality better than those from traditional clinical *** To analyze the cost disparity between surgical treatments for liver and pancreatic cancer under various *** This study analyzed RWD 1137 cases within the HB1 group(patients who underwent pancreatectomy,hepatectomy,and/or shunt surgery)in *** distinguished different expenditure categories,including medical,nursing,technical,management,drug,and consumable ***,it assessed the contribution of each expenditure category to total hospital costs and performed cross-group comparisons using the non-parametric Kruskal–Wallis *** study used the Steel–Dwass test for post-hoc multiple comparisons and the Spearman correlation coefficient to examine the relationships between *** The study found that in HB11 and HB13,the total hospitalization costs were significantly higher for pancreaticoduodenectomy than for pancreatectomy and *** no significant difference was observed in the length of hospital stay between patients who underwent pancreaticoduodenectomy and pancreatectomy,both were significantly longer than those who underwent liver *** HB15,no significant difference was observed in the total cost of hospitalization between pancreaticoduodenectomy and pancreatectomy;however,both were significantly higher than those in ***,the length of hospital stay was significan

关键词： China health care security diagnosis-related groups Real-world study Liver cancer surgical treatment Pancreatic cancer surgical treatment Hospitalization costs Cost structure Average length of stay

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Effect of initial ammonium concentration on a one-stage partial nitrification/anammox biofilm system:Nitrogen removal performance and the microbial community

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Journal of Environmental Sciences 2024年第9期143卷 176-188页

作者： Mengyu zhou yun Han Yang zhuo Fen yu Gaoyuan Hu Dangcong Peng School of Municipal and Environmental Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Shaanxi Key Laboratory of Environmental Engineering Xi’an University of Architecture and TechnologyXi’an 710055China Key Laboratory of Northwest Water Resource Environment and EcologyMOEXi’an University of Architecture and TechnologyXi’an 710055China

One-stage partial nitrification coupled with anammox(PN/A)technology effectively reduces the energy consumption of a biological nitrogen removal *** nitrite-oxidizing bacteria(NOB)is essential for this technology to maintain efficient nitrogen removal *** ammonium concentration(IAC)affects the degree of inhibited *** this study,the effect of the IAC on a PN/A biofilm was investigated in a moving bed biofilm *** results showed that nitrogen removal efficiency decreased from 82.49%±1.90%to 64.57%±3.96%after the IAC was reduced from 60 to 20 mg N/L,while the nitrate production ratio increased from 13.87%±0.90%to 26.50%±3.76%.NOB activity increased to1,133.86 mg N/m^(2)/day after the IAC decreased,approximately 4-fold,indicating that the IAC plays an important inhibitory role in *** rate-limiting step in the mature biofilm of the PN/A system is the nitritation process and is not shifted by the *** analysis of the microbial community structure in the biofilm indicates that the IAC was the dominant factor in changes in community *** and *** were the main anammox bacteria,and Nitrosomonas and Nitrospira were the main AOB and NOB,*** did not affect the difference in growth between *** and ***,modulating the IAC promoted the PN/A process with efficient nitrogen removal performance at medium to low ammonium concentrations.

关键词： Biological nitrogen removal Partial nitrification Anammox Ammonium concentration Biofilm

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Study on hydrodynamic diffusion law of the swelling particle slurry in karst pipeline

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Particuology 2024年第4期87卷 218-231页

作者： Bingchuan Cheng Haibo Li Guangming Pan Runhuai Deng yu'an Gong Shujun Xu Kun zhou zhuo Zheng School of Civil Engineering Geotechnical and Structural Engineering Research CenterShandong UniversityJinan250061China The Fourth Prospecting of Shandong Coal Geology Bureau Weifang261000China China Railway 14th Bureau Group Corporation Limited Jinan250101China School of Trafic Engineering Shandong Jianzhu University.Fengming RoadLingang Development ZoneJinan250101China

The swelling particle grouting material has demonstrated remarkable plugging effectiveness in high-pressure and large-flow burst water within karst ***,current research on the rheolog-ical model,flow computation theory,and plugging mechanism of this material is *** conven-tional grouting slurry diffusion process,using the liquid-liquid two-phase flow method,fails to accurately simulate high solubility slurry and particle *** address these limitations,this study established a precise constitutive model to describe the swelling particle slurry diffusion process in dynamic ***,a coupling calculation method was proposed to analyze the spatiotemporal heterogeneity of viscosity during slurry diffusion by considering the migration of slurry and the changes in *** investigate the interaction between particle swelling and flow field changes,a Compu-tational Fluid Dynamics-Discrete Element Method(CFD-DEM)coupling model was developed for the diffusion of swelling particle *** is demonstrated that slurry viscosity increases exponentially within the diffusion front as the particle swelling rate rises,and the drag force exhibits an intriguing behavior of initially increasing and then decreasing as the slurry flows through the ***-more,the CFD-DEM coupling model proved to be more accurate in describing viscosity distribution and diffusion distance compared to the finite element *** primary objective of this paper is to reveal the plugging mechanism and provide theoretical support for the engineering application of the swelling particle grouting material.

关键词： Karst pipeline Swelling particle grouting material Dynamic water diffusion Spatiotemporal variation of viscosity CFD-DEM coupling model

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Relative Broken Family Sensitivity

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Acta Mathematica Sinica,English Series 2024年第9期40卷 2297-2306页

作者： zhuo Wei LIU Tao yu Department of Mathematics Shantou UniversityShantou 515063P.R.China

Letπ:(X,T)→(Y,S)be a factor map between two topological dynamical systems,and F_(a) Furstenberg family of *** introduce the notion of relative broken *** Fs(***,Finf)be the families consisting of all syndetic subsets(*** upper Banach density subsets,infinite subsets).We show that for a factor mapπ:(X,T)→(Y,S)between transitive systems,πis relatively broken F-sensitive for F=Fs or Fpubd if and only if there exists a relative sensitive pair which is an F-recurrent point of(R_(π),T^((2)));is relatively broken Finf-sensitive if and only if there exists a relative sensitive pair which is not *** a factor mapπ:(X,T)→(Y,S)between minimal systems,we get the structure of relative broken F-sensitivity by the factor map to its maximal equicontinuous factor.

关键词： Relative sensitivity recurrent points Furstenberg family relative sensitive pairs maximal equicontinuous factor

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Embracing the age of artificial intelligence:paradigm shifts,opportunities,and challenges in the treatment of acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

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Science China(Life Sciences) 2024年第6期67卷 1302-1304页

作者： zhuo-yu An Xiao-Hui Zhang Peking University People’s Hospital Peking University Institute of HematologyBeijing 100044China Collaborative Innovation Center of Hematology Peking UniversityBeijing 100044China Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation Beijing 100044China National Clinical Research Center for Hematologic Disease Beijing 100044China

Allogeneic hematopoietic stem cell transplantation(allo-HSCT)is an important medical development in treating hematological ***,the risk of acute graft-versus-host disease(a GVHD)severely limits its use.a GVHD is a sev... 详细信息

关键词： hematopoietic graft artificial

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Dual-salt poly(tetrahydrofuran)electrolyte enables quasi-solid-state lithium metal batteries to operate at−30℃

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Journal of Energy Chemistry 2024年第9期96卷 456-463页

作者： Zhiyong Li zhuo Li Rui yu Xin Guo School of Materials Science and Engineering State Key Laboratory of Material Processing and Die&Mould TechnologyHuazhong University of Science and TechnologyWuhan 430074HubeiChina The State Key Laboratory of Refractories and Metallurgy and Institute of Advanced Materials and Nanotechnology Wuhan University of Science and TechnologyWuhan 430081HubeiChina

The stable operation of solid-state lithium metal batteries at low temperatures is plagued by severe restrictions from inferior electrolyte-electrode interface compatibility and increased energy barrier for Li^(+)***,we prepare a dual-salt poly(tetrahydrofuran)-based electrolyte consisting of lithium hexafluorophosphate and lithium difluoro(oxalato)borate(LiDFOB).The Li-salt anions(DFOB−)not only accelerate the ring-opening polymerization of tetrahydrofuran,but also promote the formation of highly ion-conductive and sustainable interphases on Li metal anodes without sacrificing the Li^(+)conductivity of electrolytes,which is favorable for Li^(+)transport kinetics at low *** of this polymer electrolyte in Li||LiFePO_(4)cells show 82.3%capacity retention over 1000 cycles at 30℃and endow stable discharge capacity at−30℃.Remarkably,the Li||LiFePO4 cells retain 52%of their room-temperature capacity at−20℃and 0.1 *** rational design of dual-salt polymer-based electrolytes may provide a new perspective for the stable operation of quasi-solid-state batteries at low temperatures.

关键词： Poly(tetrahydrofuran) Dual-salt electrolyte Solidel ectrolyte interphase Low-temperature operation Quasi-solid-state battery

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Endosulfan residues and farmers’replacement behaviors of endosulfan in the north-west inland cotton region

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 35-47页

作者： Shuyan zhou Yang Zhang Jingjing Wang Shikun Cheng Fuyan zhuo yun Hong School of Energy and Environmental Engineering University of Science and Technology Beijing 100083China Foreign Environmental Cooperation Center Ministry of Ecology and Environment of the People’s Republic of ChinaBeijing 100035China United Nations Development Programme in China Beijing 100600China National Agro-Tech Extension and Service Center Beijing 100125China

We assessed the situation of endosulfan residues in cotton fields after the endosulfan ban came into effect and the current knowledge,attitude,and practice(KAP)of cotton farmers on the phase-out of endosulfan and the application of alternative *** samples(n=91)of cotton fields were collected from the major cotton-producing areas in China,namely the north-west inland cotton region,and the endosulfan residues were analyzed.A KAP survey was carried out for cotton farmers,and 291 questionnaires were *** influences of gender,age,education background,cotton planting years,publicity and training,income sources,and other factors on cotton farmers’KAP were *** results showed that endosulfan sulfate was the main endosulfan residue in the soil,followed byβ-endosulfan andα-endosulfan,the average residual contents were 0.569,0.139,and 0.060μg/kg,*** results of the KAP study showed that cotton farmers scored low on knowledge about the phase-out of endosulfan and the application of alternative technologies but high on attitude and *** number of family members,years of cotton planting,age,and the cottonplanting area had different degrees of influence on KAP *** training could significantly improve the KAP scores of cotton farmers;training should be more targeted and designed reasonably for key groups,such as men and the population under 30,followed by training them to use pesticides *** large-scale cotton growers,training should focus on green prevention and control technologies.

关键词： Cotton fields Endosulfan residues Farmers KAP survey Replacement behaviours

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Investigating the elliptic anisotropy of identified particles in p-Pb collisions with a multi-phase transport model

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Nuclear Science and Techniques 2024年第2期35卷 160-169页

作者： Si-yu Tang Liang Zheng Xiao-Ming Zhang Ren-zhuo Wan School of Mathematical and Physical Sciences Wuhan Textile UniversityWuhan 430200China School of Mathematics and Physics China University of Geosciences(Wuhan)Wuhan 430074China Key Laboratory of Quark and Lepton Physics(MOE)and Institute of Particle Physics Central China Normal UniversityWuhan 430079China Hubei Key Laboratory of Digital Textile Equipment Wuhan Textile UniversityWuhan 430200China School of Electronic and Electrical Engineering Wuhan Textile UniversityWuhan 430200China

The elliptic azimuthal anisotropy coefficient(v_(2))of the identified particles at midrapidity(|η|<0.8)was investigated in p-Pb collisions at√s_(NN)=5.02 TeV using a multi-phase transport model(AMPT).The calculations of differential v_(2)based on the advanced flow extraction method of light flavor hadrons(pions,kaons,protons,andΛ)in small collision systems were extended to a wider transverse momentum(p_(T))range of up to 8 GeV/c for the first *** string-melting version of the AMPT model provides a good description of the measured p_(T)-differential v_(2)of the mesons but exhibits a slight deviation from the baryon v_(2).In addition,we observed the features of mass ordering at low p_(T)and the approximate number-of-constituentquark(NCQ)scaling at intermediate p_(T).Moreover,we demonstrate that hadronic rescattering does not have a significant impact on v_(2)in p-Pb collisions for different centrality selections,whereas partonic scattering dominates in generating the elliptic anisotropy of the final *** study provides further insight into the origin of collective-like behavior in small collision systems and has referential value for future measurements of azimuthal anisotropy.

关键词： Azimuthal anisotropy Small collision systems Transport model

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A highly sensitive multiple-mode optical thermometer designed in Eu^(2+)/^(3+)and Li^(+)co-doped polymorphism compound LaSc_(3)(BO_(3))_(4)

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Journal of Advanced Ceramics 2024年第6期13卷 821-833页

作者： Nan Yang zhuo Li Tingxia zhou Ziwang Zhang Wen Shi Yexiang Tong Jianxin Shi School of Chemistry IGCMESun Yat-sen UniversityGuangzhou 510006China MOE of the Key Laboratory of Bioinorganic and Synthetic Chemistry IGCMEThe Key Lab of Low-Carbon Chemistry&Energy Conservation of Guangdong ProvinceSun Yat-sen UniversityGuangzhou 510006China

Noncontact optical thermometers have attracted widespread attention,but existing problems such as single-mode and low-sensitivity thermometers still urgently need to be ***,a novel multiple-mode thermometer was designed for the polymorphism LaSc_(3)(BO_(3))_(4):Eu^(2+/3+),Li^(+).X-ray diffraction(XRD)patterns revealed a slight transition betweenα-andβ-phases with the concentrations of the dopants,which is further proved by structure refinements and first-principles *** coexistence of Eu^(2+)and Eu^(3+)in the phosphors and their relative percentages were confirmed by X-ray absorption near-edge structure(XANES)*** from appropriate emissions from Eu^(2+)and Eu^(3+)without obvious energy transfer and their opposite changing trends with temperatures under 307 nm excitation,a triple-mode optical thermometer is obtained for this material within the temperature range of 150–450 *** highest sensitivities of 27.65,14.05,and 7.68%·K^(−1)are achieved based on two fluorescence intensity ratio(FIR)modes of Eu^(2+)and Eu^(3+)(5d–4f/^(5)D_(0)–^(7)F_(2,4))and the fluorescence lifetime(FL)mode of Eu^(2+),*** the best of our knowledge,the former is almost the highest in Eu^(2+)and Eu^(3+)co-doped *** results indicate that this material may be used as an excellent multiple-mode optical thermometer.

关键词： phase transition europium(Eu)ions multiple-mode optical thermometer thermal quenching properties fluorescence intensity ratio(FIR) fluorescence lifetime(FL)

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C634Y mutation in RET-induced multiple endocrine neoplasia type 2A:A case report

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World Journal of Clinical Cases 2024年第15期12卷 2627-2635页

作者： Hui-Fen Zhang Shu-Ling Huang Wen-Li Wang yu-Qing zhou Jun Jiang zhuo-Jin Dai Department of Endocrinology Dongguan Hospital of Guangzhou University of Chinese MedicineDongguan 523003Guangdong ProvinceChina Department of Science and Technology Services Beijing Macro and Micro Test Co.Ltd.Beijing 100318China The First Clinical Medical College Guangdong Medical UniversityZhanjiang 524023Guangdong ProvinceChina

BACKGROUND Multiple endocrine neoplasia type 2(MEN2)is a rare,autosomal dominant endocrine ***,the RET proto-oncogene is the only gene implicated in MEN2A *** an RET carrier is detected,family members should be screened to enable early detection of medullary thyroid carcinoma,pheochromocytoma,and *** these,medullary thyroid carcinoma is the main factor responsible for patient ***,delineating strategies to inform clinical follow-up and treatment plans based on genes is paramount for clinical *** SUMMARY Herein,we present RET proto-oncogene mutations,clinical characteristics,and treatment strategies in a family with MEN2A.A family study was conducted on patients diagnosed with *** was extracted from the peripheral blood of family members,and first-generation exon sequencing of the RET protooncogene was *** C634Y mutation was identified in three family members spanning three *** patients were sequentially diagnosed with pheochromocytomas and bilateral medullary thyroid carcinomas.A 9-yearold child harboring the gene mutation was diagnosed with medullary thyroid *** resection of the tumors was *** family members were advised to undergo complete genetic testing related to the C634Y mutation,and the corresponding treatments administered based on test results and associated clinical *** Advancements in MEN2A research are important for familial management,assessment of medullary thyroid cancer invasive risk,and deciding surgical timing.

关键词： Multiple endocrine neoplasia type 2A Mutation RET proto-oncogene Medullary thyroid carcinoma Pheochromocytoma Case report

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