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The breaking of spin symmetry in the single-particle resonances in deformed nuclei

Nuclear Science and Techniques 2024年第3期35卷 237-245页

作者： zhen-yu zheng Shou-Wan Chen Quan Liu School of Physics and Optoelectronic Engineering Anhui UniversityHefei 230601China

The exploration of spin symmetry (SS) in nuclear physics has been instrumental in identifying atomic nucleus *** this study,we solve the Dirac equation from the relativistic mean field (RMF) in complex momentum *** investigated SS and its breaking in single-particle resonant states within deformed nuclei,with a focus on the illustrative *** was the initial discovery of a resonant spin doublet in a deformed nucleus,with the expectation of the SS approaching the continuum *** increasing single-particle energy,the splitting of the resonant spin doublets widened *** escalating splitting implies diminishing adherence to the SS,indicating a departure from the expected behavior as the energy levels *** also analyzed the width of the resonant states,showing that lower orbital angular momentum resonances possess shorter decay times and that SS is preserved within broad resonant doublets,as opposed to narrow resonant *** the radial density of the upper components for the bound-state and resonant-state doublets,it becomes evident that while SS is well-preserved in the bound states,it deteriorates in the resonant *** impact of nuclear deformation (β_(2)) on SS was examined,demonstrating that an increase in β_(2) resulted in higher energy and width splitting in the resonant spin doublets,which is attributed to increased component ***,the sensitivity of spin doublets to various potential parameters such as surface diffuseness (a),radius (R),and depth (Σ0) is discussed,emphasizing the role of these parameters in *** study provides valuable insights into the behavior of spin doublets in deformed nuclei and their interplay with the nuclear structure,thereby advancing our understanding of SS in the resonance state.

关键词： Spin symmetry Resonant states Deformed nuclei Complex-momentum representation

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Signal molecule-mediated hepatic cell communication during liver regeneration

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World Journal of Gastroenterology 2009年第46期15卷 5776-5783页

作者： zhen-yu zheng Shun-Yan Weng Yan yu School of Agricultureand Biology Shanghai Jiao Tong University Shanghai 200240China

Liver regeneration is a complex and well-orchestrated process,during which hepatic cells are activated to produce large signal molecules in response to liver injury or mass *** signal molecules,in turn,set up the connections and cross-talk among liver cells to promote hepatic *** this review,we endeavor to summarize the network of signal molecules that mediates hepatic cell communication in the regulation of liver regeneration.

关键词： Signal molecule Hepatic cells Cellular cross-talk Signal communication Liver regeneration

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Resectable left lower lobe non-small cell lung cancer with lymph node metastasis is related to unfavorable outcomes

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Chinese Journal of Cancer 2016年第1期35卷 35-42页

作者： Wen-Feng Ye Xuan Xie Hong Yang Kong-Jia Luo Qian-Wen Liu yu-zhen zheng Jun-Ye Wang State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer MedicineSun Yat-sen University Cancer Center Department of Clinical Nutrition Sun Yat-sen University Cancer Center Department of Thoracic Surgery Sun Yat-sen Memorial HospitalSun Yat-sen University Department of Thoracic Oncology Sun Yat-sen University Cancer Center

Background:Despite numerous previous studies,the consideration of tumor location as a prognostic factor in resectable non-small cell lung cancer(NSCLC)remains *** present study analyzed the association between tumor location and clinical outcome in patients with resectable NSCLC who had undergone lobectomy with systematic lymphadenectomy and who had presented with varying nodal ***:The data from a cohort of 627 eligible patients treated in Sun Yat-sen University Cancer Center between January 2000 and December 2008 were retrospectively collected,and the nodal statuses of patients with different tumor locations were *** proportional hazards regression model was used to determine the independent factors related to cancer-specific survival(CSS).Results:Multivariate analysis demonstrated that left lower lobe(LLL)tumors[hazard ratio(HR):1.465,95%confidence interval(CI)1.090-1.969,P=0.011],lymph node metastasis(HR:2.742,95%CI 2.145-3.507,P4 cm(HR:1.474,95%CI 1.151-1.888,P=0.002)were three independent prognosticators in patients with resectable ***,LLL tumors were associated only with CSS in node-positive patients(HR:1.528,95%CI 1.015-2.301,P=0.042),and a tumor size of>4 cm was the only independent risk predictor in the node-negative subgroup(HR:1.889,95%CI 1.324-2.696,P<0.001).Conclusions:Tumor location is related to the long-term CSS of NSCLC patients with lymph node *** tumors may be upstaged in node-positive patients to facilitate an optimal treatment strategy.

关键词： Lung cancer surgery, Lobectomy, Tumor, Outcomes, Lymph node

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A novel anastomotic vacuum-assisted closure system for cervical anastomotic fistula after three-incisional esophagectomy

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Gastroenterology Report 2023年第1期11卷 557-559页

作者： yu-zhen zheng Shen-Shen Fu Xian-yu Qin Xing-Ping Yang Hao-Sheng zheng Zui Liu Shi-yun He Wei-Jie Cai Jian Tan Bo-Zhu Jian Hong-Ying Liao Department of Thoracic Surgery The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Esophageal Surgery The Sixth Affiliated HospitalSun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Ultrasonography Guangzhou First People’s HospitalSchool of MedicineSouth China University of TechnologyGuangzhouGuangdongP.R.China

Introduction Surgery remains the mainstay treatment for localized esophageal squamous cell carcinoma(ESCC).In recent years,three-incision McKeown esophagectomy has been widely applied for operable ESCC considering its superiority in acquiring extensive lymphadenectomy and long-termsurvival[1].Cervical anastomotic fistula is one of the most dreaded complications in patients undergoing three-incision esophagectomy;it occurs in almost 10%–25%of patients and is responsible for almost 40%of post-operative deaths[2,3].Most surgeons prefer conservative approaches including perianastomotic drainage,total parenteral nutrition,nasogastric decompression,and the use of broad-spectrum antibiotics for cervical anastomotic fistula[4,5].However,the recovery period under this method is commonly long and *** now,the optimal treatment for cervical anastomotic fistula has not yet been *** this study,we describe a flushingdrainage system under negative pressure conditions to treat cervical anastomotic fistula,named anastomotic vacuum-assisted closure(AVAC).

关键词： fistula cervical Surgery

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Prognostic value of preoperative mean corpuscular volume in esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2013年第18期19卷 2811-2817页

作者： yu-zhen zheng Shu-Qin Dai Wei Li Xun Cao Yong Li Lan-Jun Zhang Jian-Hua Fu JunYe Wang Department of Thoracic Oncology Cancer Center Sun Yat-Sen University Department of Clinical Laboratory Sun Yat-Sen University Cancer Center Department of Anesthesia Sun Yat-Sen University Cancer Center Intensive Care Unit Sun Yat-Sen University Cancer Center Department of Pathology Sun Yat-Sen University Cancer Center

AIM: To evaluate whether preoperative mean corpuscular volume (MCV) is a prognostic indicator in patients with resectable esophageal squamous cell carcinoma (ESCC). METHODS: A total of 298 consecutive, prospectively enrolled patients with histologically diagnosed ESCC who underwent surgery with curative intent from 2001 to 2011 were retrospectively evaluated. Patients were excluded if they had previous malignant disease, distant metastasis at the time of primary treatment, a history of neoadjuvant treatment, had undergone nonradical resection, or had died of a non-tumor-associated cause. Survival status was verified in September 2011. Pathological staging was performed based on the 2010 American Joint Committee on Cancer criteria. Preoperative MCV was obtained from blood counts performed routinely within 7 d prior to surgery. Receiver operating characteristic (ROC) curve analysis was used to determine a cutoff for preoperative MCV. RESULTS: The 298 patients consisted of 230 males and 68 females, with a median follow-up of 30.1 mo. ROC analysis showed an optimal cutoff for preoperative MCV of 95.6 fl. Fifty-nine patients (19.8%) had high (> 95.6 fl) and 239 (80.2%) had low (≤ 95.6 fl) preoperative MCV. Preoperative MCV was significantly associated with gender (P=0.003), body mass index (P=0.017), and preoperative red blood cell count (P<0.001). The predicted 1-, 3and 5-year overall survival (OS) rates were 72%, 60% and 52%, respectively. Median OS was significantly longer in patients with low than with high preoperative MCV (27.5 mo vs 19.4 mo, P<0.001). Multivariate analysis showed that advanced pT (P=0.018) and pN (P<0.001) stages, upper thoracic location (P=0.010), lower preoperative albumin concentration (P=0.002), and high preoperative MCV (P=0.001) were negative prognostic factors in patients with ESCC. Preoperative MCV also stratified OS in patients with T3, N1-N3, G2-G3 and stage Ⅲ tumors. CONCLUSION: Preoperative MCV is a prognostic factor in patients with E

关键词： Preoperative markers Mean corpuscular volume Prognosis Resectable Esophageal neoplasms

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COMPLEX NUMBER MODE APPROACH FOR REDUCING VIBRATION OF STRUCTURAL FLEXIBLE REDUNDANT ROBOT MANIPULATORS

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Chinese Journal of Mechanical Engineering 2001年第2期14卷 102-105页

作者： Wu Licheng Sun Zengqi Sun Fuchun Department of Computer Science and Technology, Qinghua University Lu zhen yu Shouqian zheng Hong Beijing University of Aeronautics and Astronautics 清华大学计算机科学与工程系北京北京航空航天大学北京

A complex number mode analysis approach is proposed for vibration reducing of structural flexible redundant manipulators by utilizing self motion. In the proposed approach, the self motion is evaluated to nullify the modal exciting force of flexural motion, and the approach can be freely used when the degree of freedom of flexural motion is much greater than the available degree of reundancy. The availability and effectiveness of the proposed approach are demonstrated through numerical simulation with a four link spatial robotic manipulator possessing an end flexible link.

关键词： Redundant manipulators Self motion Vibration reducing Complex number mode analysis

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A U-SHAPE TRANSDUCER ARRAY OF SHALLOW WATER MULTI-BEAM SONAR SYSTEM

A U-SHAPE TRANSDUCER ARRAY OF SHALLOW WATER MULTI-BEAM SONAR...

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2012全国压电和声波理论及器件技术研讨会

作者： zhen-yu zheng Science and Technology on Sonar Laboratory Hangzhou Applied Acoustics Research Institute

The equivalent circuit model of piezoelectric ceramic pillar transducer with matching layer material is proposed,and the applicability of this model in the U-shape transducer array is *** vibration character and directivity pattern of the transducer are analyzed by the finite element *** manufactured U-shape transducer array has verified feasibility of the piezoelectric ceramic pillar transducer with matching layer *** broadband and high power density characters of such design are suitable for high frequency broadband acoustic emission with special directivity.

关键词： U-shape array Multi-beam sonar FEM

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Managing esophageal fistulae by endoscopic transluminal drainage in esophageal cancer patients with superior mediastinal sepsis after esophagectomy

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Chinese Journal of Cancer 2013年第8期32卷 469-473页

作者： yu-zhen zheng Shu-Qin Dai Hong-Bo Shan Xiao-Yan Gao Lan-Jun Zhang Xun Cao Jian-Fei Zhu Jun-Ye Wang State Key Laboratory of Oncology in South China Department of Thoracic Oncology Sun Yat-sen University Cancer Center Clinical Laboratory Sun Yat-sen University Cancer Center Department of Laser and Endoscopy Sun Yat-sen University Cancer Center

The management of postoperative leaks into the mediastinum after esophagectomy remains a challenge. We describe our clinical management of this complication through endoscopic transluminal drainage. Between 2008 and 2011, 4 patients with esophageal squamous cell carcinoma (ESCC) who underwent McKeown-type esophagectomy with two-field lymphadenectomy experienced complicated anastomotic fistulae in the presence of superior mediastinal sepsis. All 4 patients underwent endoscopic transluminal drainage, and all survived. The mean healing period was 50 days (range, 31 to 58 days), the mean stay in the intensive care unit was 7.3 days (range, 1 to 18 days), and the mean hospital stay was 64.5 days (range, 49 to 70 days). Endoscopically guided transluminal drainage should be considered for ESCC patients with superior mediastinal fistulae after esophagectomy.

关键词：临床管理食管癌败血症引流腔内内镜患者鳞状细胞癌

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Comparison between different reconstruction routes in esophageal squamous cell carcinoma

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World Journal of Gastroenterology 2012年第39期18卷 5616-5621页

作者： yu-zhen zheng Shu-Qin Dai Wei Li Xun Cao Xin Wang Jian-Hua Fu Peng Lin Lan-Jun Zhang Bin Lu Jun-Ye Wang Department of Thoracic Oncology Sun Yat-Sen University Cancer Center Guangzhou 510060 Guangdong Province China Department of Clinical Laboratory Sun Yat- Sen University Cancer Center Guangzhou 510060 Guangdong Province China Department of Anesthesia Sun Yat-Sen University Can-cer Center Guangzhou 510060 Guangdong Province China

AIM:To compare postoperative complications and prognosis of esophageal squamous cell carcinoma patients treated with different routes of reconstruction. METHODS:After obtaining approval from the Medical Ethics Committee of the Sun Yat-Sen University Cancer Center, we retrospectively reviewed data from 306 consecutive patients with histologically diagnosed esophageal squamous cell carcinoma who were treated between 2001 and 2011. All patients underwent radical McKeown-type esophagectomy with at least two-field lymphadenectomy. Regular follow-up was performed in our outpatient department. Postoperative complica-tions and long-term survival were analyzed by treatment modality, baseline patient characteristics, and operative procedure. Data from patients treated via the retrosternal and posterior mediastinal routes were compared. RESULTS:The posterior mediastinal and retrosternal reconstruction routes were employed in 120 and 186 patients, respectively. Pulmonary complications were the most common complications experienced during the postoperative period (46.1% of all patients; 141/306). Compared to the retrosternal route, the posterior mediastinal reconstruction route was associated with a lower incidence of anastomotic stricture (15.8% vs 27.4%, P = 0.018) and less surgical bleeding (242.8 ± 114.2 mL vs 308.2 ± 168.4 mL, P < 0.001). The median survival time was 26.8 mo (range:1.6-116.1 mo). Upon uni/multivariate analysis, a lower preoperative albumin level (P = 0.009) and a more advanced pathological stage (pT; P = 0.006; pN; P < 0.001) were identified as independent factors predicting poor prognosis. The reconstruction route did not influence prognosis (P = 0.477). CONCLUSION:The posterior mediastinal route of reconstruction reduces incidence of postoperative complications but does not affect survival. This route is recommended for resectable esophageal squamous cell carcinoma.

关键词： Esophageal carcinoma Route of reconstruc-tion Posterior mediastinal Retrosternal Comparison

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Combined microneurosurgical and thoracoscopic resection for thoracic spine dumbbell tumors

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Chinese Medical Journal 2008年第12期121卷 1137-1139页

作者： WANG zhen-yu LIANG zheng LIU Bin CHENG Xiao-dong ZHANG Jia Department of Neurosurgery Peking University Third Hospital Beijing 100083 China

Dumbbell tumors have both intraspinal and anterior paraspinal components connected through anintervertebral foramen. Most of these tumors are neurogenic and include schwannomas, neurofibromas, ganglioneuromas and neuroblastomas. ***, more than 90% of these tumors are benign.2. Dumbbell tumors of the thoracic spine are particularly difficult to expose and remove by virtue of their location and relationship with vital structures of the thoracic cavity. The traditional surgical approach for removing these tumors has been using either combined anterior thoracotomy and posterior neurosurgical procedures or the lateral extracavitary approach. We present our experience with resection of three dumbbell tumors with a combined microneurosurgical and thoracoscopic procedures in a single stage.

关键词： spinal canal dumbbell tumor endoscopy minimal invasive surgery

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