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Surgical intervention combined with weight-bearing walking training promotes recovery in patients with chronic spinal cord injury:a randomized controlled study

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Neural Regeneration Research 2024年第12期19卷 2773-2784页

作者： Hui Zhu James D.guest Sarah Dunlop Jia-Xin Xie Sujuan gao Zhuojing Luo Joe E.Springer Wutian Wu Wise Young wai Sang Poon Song Liu Hongkun gao Tao yu Dianchun wa.g Libing Zhou Shengping Wu Lei Zhong Fang Niu Xiaomei wa.g Yansheng Liu Kwok-Fai So Xiao-Ming Xu Kunming Tongren Hospital KunmingYunnan ProvinceChina Neurological Surgery and the Miami Project to Cure ParalysisMiller School of MedicineUniversity of MiamiMiamiFLUSA School of Biological Sciences The University of Western AustraliaPerthWAAustralia Minderoo Foundation PerthWAAustralia Clinical Center for Spinal Cord Injury Kunming General Hospital of Chengdu Military CommandKunmingYunnan ProvinceChina Department of Biostatistics and Health Data Science Indiana University School of MedicineIndianapolisINUSA Department of Orthopedic Spinal Surgery Xijing HospitalFourth Military Medical UniversityXi’anShaanxi ProvinceChina Spinal Cord and Brain Injury Research Center Department of Physical Medicine and RehabilitationUniversity of Kentucky College of MedicineLexingtonKYUSA guangdong-HongKong-Macao Institute of CNS Regeneration Jinan UniversityGuangzhouGuangdong ProvinceChina W.M.Keck Center for Collaborative Neuroscience Rutgers UniversityPiscatawayNJUSA Neurosurgery Department Chinese University of Hong KongPrince of Wales HospitalHong Kong Special Administration RegionChina Spinal Cord and Brain Injury Research group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA

For patients with chronic spinal cord injury,the co nventional treatment is rehabilitation and treatment of spinal cord injury complications such as urinary tract infection,pressure sores,osteoporosis,and deep vein *** is rarely perfo rmed on spinal co rd injury in the chronic phase,and few treatments have been proven effective in chronic spinal cord injury *** of effective therapies fo r chronic spinal co rd injury patients is *** conducted a randomized controlled clinical trial in patients with chronic complete thoracic spinal co rd injury to compare intensive rehabilitation(weight-bearing walking training)alone with surgical intervention plus intensive *** clinical trial was registered at ***(NCT02663310).The goal of surgical intervention was spinal cord detethering,restoration of cerebrospinal fluid flow,and elimination of residual spinal cord *** found that surgical intervention plus weight-bearing walking training was associated with a higher incidence of American Spinal Injury Association Impairment Scale improvement,reduced spasticity,and more rapid bowel and bladder functional recovery than weight-bearing walking training ***,the surgical procedures and intensive rehabilitation were *** Spinal Injury Association Impairment Scale improvement was more common in T7-T11 injuries than in T2-T6 *** combined with rehabilitation appears to have a role in treatment of chronic spinal cord injury patients.

关键词： chronic spinal cord injury intensive rehabilitation locomotor training neurological recovery surgical intervention weightbearing walking training

抗-E、抗-c、抗-M、抗-S多重抗体分析

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中国输血杂志 2024年第5期37卷 511-515,533页

作者：高娃李冰班凤禹王秋实中国医科大学附属盛京医院输血科辽宁沈阳110004

目的对1例存在多重抗体的肾积水伴输尿管结石合并休克老年患者进行抗体特异性鉴定。方法微柱凝胶法进行红细胞不规则抗体筛查和抗体鉴定,酶法,抗体吸收法协助判断患者的抗体特异性;盐水试管法检测患者ABO血型鉴定、Rh血型鉴定、MNS血型... 详细信息

目的对1例存在多重抗体的肾积水伴输尿管结石合并休克老年患者进行抗体特异性鉴定。方法微柱凝胶法进行红细胞不规则抗体筛查和抗体鉴定,酶法,抗体吸收法协助判断患者的抗体特异性;盐水试管法检测患者ABO血型鉴定、Rh血型鉴定、MNS血型。结果患者血型:O、CCDee、NNss,患者体内检测出抗-E、抗-c、抗-M、抗-S联合抗体。结论反复输血可能引起患者存在1种或者多种意外抗体,体内多种或高频率抗体的患者,可能引起鉴定困难和用血延迟。

关键词：多重抗体抗体鉴定

Impact of climate change on outdoor design conditions and implications to peak loads

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Building Simulation 2022年第12期15卷 2051-2065页

作者： Xujie Huo Liu Yang Danny Hin wa Li Isaac Lun Siwei Lou yuan Shi School of Architecture&Urban Planning Shenzhen UniversityShenzhen 518060China Benyuan Design and Research Center Shenzhen UniversityShenzhen 518060China Shenzhen Key Laboratory of Architecture for Health&Well-being(in preparation) Shenzhen 518060China School of Architecture Xi’an University of Architecture and TechnologyXi’an 710055China Building Energy Research group Department of Architecture and Civil EngineeringCity University of Hong KongHong KongChina Centre for Sustainable Energy Technologies University of Nottingham Ningbo ChinaNingbo 315100China School of Civil Engineering Guangzhou UniversityGuangzhou 510006China

This study exams the impact of climate change on outdoor design conditions and peak loads of five Chinese cities over the five major climate zones for the winter and summer *** design dry-bulb temperature(DDBT)and the coincident wet-bulb temperature(CWBT)for two 30-year periods;1971–2000 and 1984–2013 were *** was found that the DDBT of the period 1984–2013 was higher than that of the period 1971–2000,whereas the CWBT and the corresponding outdoor enthalpy of the period 1984–2013 was lower than that of 1971–2000 at the various cumulative *** trend implies that the increment in conductive heat gain through the building envelope due to the rising temperature can be lower than the reduction in fresh air load due to the lower outdoor air *** this case,the peak cooling loads may reduce in all five cities under study,and this is different from the widely held view that global warming will lead to more stringent outdoor design conditions,higher peak cooling loads and larger heating,ventilation and air conditioning(HVAC)plants than the current or historical *** implications to the“free-cooling”of HVAC systems with enthalpy control are discussed as well.

关键词： outdoor design conditions outdoor air enthalpy climate change peak loads

Physical activity and amyloid beta in middle-aged and older adults:A systematic review and meta-analysis

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Journal of Sport and Health Science 2024年第2期13卷 133-144页

作者： María Rodriguez-Ayllon Patricio Solis-Urra Cristina Arroyo-ávila Miriam álvarez-Ortega Pablo Molina-garcía Cristina Molina-Hidalgo Manuel gómez-Río Belinda Brown Kirk I.Erickson Irene Esteban-Cornejo Department of Epidemiology Erasmus University Medical Center RotterdamRotterdamGD 3015the Netherlands Department of Physical Education and Sports Faculty of Sport SciencesSport and Health University Research Institute(iMUDS)University of GranadaGranada 18071Spain Faculty of Education and Social Sciences Universidad Andres BelloVina del Mar 2531015Chile Department of Nuclear Medicine Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Physical Medicine and Rehabilitation Service Virgen de las Nieves University HospitalInstitute of Biosanitary Research of Granada(IBS)Granada 18014Spain Department of Psychology University of PittsburghPittsburghPA 15260USA Centre for Healthy Ageing Health Futures InstituteMurdoch UniversityMurdochWA 6150Australia School of Medical and Health Sciences Edith Cowan UniversityJoondalupWA 6027Australia Advent Health Research Institute Neuroscience Institute OrlandoOrlandoFL 32803USA Physiopathology of Obesity and Nutrition Research Center(CIBERobn) Institute of Health Carlos Ⅲ(ISCⅢ)Madrid 28029Spain

Background:One of the pathological hallmarks distinguishing Alzheimer’s disease from other dementias is the accumulation of amyloid beta(Aβ).Higher physical activity is associated with decreased dementia risk,and one potential path could be through Aβlevels *** aimed to explore the relationship between physical activity and Aβin middle-aged and older ***:A systematic search of PubMed,Web of Science,PsycINFO,Cochrane Central Register of Controlled Trials,and SPORTDiscus was performed from inception to April 28,*** were eligible if they included physical activity and Aβdata in adults aged 45 years or ***-level metaanalyses of intervention and observational studies were performed to examine the role of physical activity in modulating Aβ***:In total,37 articles were included(8 randomized controlled trials,3 non-randomized controlled trials,4 prospective longitudinal studies,and 22 cross-sectional studies).The overall effect size of physical activity interventions on changes in blood Aβwas medium(pooled standardized mean difference=-0.69,95%confidence interval(95%CI):-1.41 to 0.03;I^(2)=74.6%).However,these results were not statistically significant,and there were not enough studies to explore the effects of physical activity on cerebrospinal fluid(CSF)and brain Aβ.Data from observational studies were examined based on measurements of Aβin the brain using positron emission tomography scans,CSF,and *** physical activity was positively associated with Aβonly in the CSF(Estimate r=0.12;95%CI:0.05-0.18;I^(2)=38.00%).Conclusion:Physical activity might moderately reduce blood Aβin middle-aged and older ***,results were only near statistical significance and might be interpreted with caution given the methodological limitations observed in some of the included *** observational studies,higher levels of physical activity were positively associated with Aβonly in ***,further research is needed t

关键词： Aging Cognitive impairment Dementia Exercise PET

Numerical investigation on the effects of current headings on vortex induced motions of a semi-submersible

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Journal of Hydrodynamics 2022年第3期34卷 382-394页

作者： Wei-wen Zhao Zhi-yuan Wei De-cheng wa Computational Marine Hydrodynamics Lab(CMHL) School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China Marine Design&Research Institute of China Shanghai200011China Ocean College Zhejiang UniversityZhoushan316021China

In this paper,numerical simulations on vortex-induced motions(VIM)of a semi-submersible at two different current headings are conducted over a wide range of current *** simulations are performed with the computational fluid dynamics(CFD)solver VIM-FOAM-SJTU which is an in-house solver developed based on the OpenFOAM *** turbulent flows are resolved with a shear stress transport-delayed detached eddy simulation(SST-DDES)*** decay tests for transverse and yaw motion are performed in calm still water to make sure the equivalent stiffness is setup *** the results of VIM,including motion response,forces and moments,and flow patterns are presented and analyzed *** including transverse,in-line and yaw motion at different current headings and velocities are *** vorticity in the wake regions at different time stamps are also illustrated for different current headings and velocities.

关键词： Vortex-induced motions(VIM) vortex-induced yaw vim-FOAM-SJTU solver Reynolds stress

民国知识分子对贺川丰彦社会思想的评价与接受

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日语学习与研究 2024年第2期 10-23页

作者：庾凌峰安徽大学外语学院

贺川丰彦是日本大正·昭和战前时期著名的社会思想家、社会运动家和作家。贺川从“生命”“劳动”和“人格”三个核心概念出发,建构了以贫民救济思想、劳动思想和劳动诗学为中心的社会思想并付诸实践。贺川的社会思想发展成为日本大正... 详细信息

贺川丰彦是日本大正·昭和战前时期著名的社会思想家、社会运动家和作家。贺川从“生命”“劳动”和“人格”三个核心概念出发,建构了以贫民救济思想、劳动思想和劳动诗学为中心的社会思想并付诸实践。贺川的社会思想发展成为日本大正时期重要的社会思潮,其提出的“生命”“劳动”以及“人格”所演变的生命第一要义、劳工神圣论以及社会发展阶段论等思想受到陈达、陈独秀、李大钊、李达、田汉等民国知识分子的关注,成为二十世纪二十年代前后国内学者研究日本社会思想史的重要媒介。贺川的社会思想和实践鼓舞了早期具有共产主义思想的知识分子进行劳动运动的决心和勇气,成为民国知识分子通过日本途径吸收马克思主义思想的重要来源。

关键词：贺川丰彦社会思想民国知识分子劳动运动

仙人掌状的NC/Co_(x)P自支撑电极用于盐水电解实现高效稳定析氢

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新型炭材料（中英文） 2024年第1期39卷 152-163页

作者：陈续赵金玉张文盛王晓敏太原理工大学材料科学与工程学院山西太原030024

设计高效、稳定的析氢催化剂是盐水电解技术发展的必然要求。本文通过原位生长策略在泡沫镍(NF)上生长NC/Co_(x)P@NF催化剂,它由Co_(x)P纳米线阵列与氮掺杂碳纳米片(NC)交替生长组成。在制备过程中,Co(OH)_(2)纳米线通过内源Co^(2+)与2... 详细信息

设计高效、稳定的析氢催化剂是盐水电解技术发展的必然要求。本文通过原位生长策略在泡沫镍(NF)上生长NC/Co_(x)P@NF催化剂,它由Co_(x)P纳米线阵列与氮掺杂碳纳米片(NC)交替生长组成。在制备过程中,Co(OH)_(2)纳米线通过内源Co^(2+)与2-甲基咪唑的溶解配位作用在NF上原位转化为Co-MOF纳米片。仙人掌状的微观结构使NC/CoxP@NF暴露出丰富的活性位点和离子运输通道,促进了HER催化反应动力学。此外,在分级多孔的NC/CoxP@NF中,纳米线和自支撑纳米片交替生长,进一步增强了材料的结构稳定性。最重要的是,表面聚阴离子(磷酸盐)和NC纳米片保护层的形成提高了催化剂的耐腐性能。最终,NC/CoxP@NF-10表现出优异的析氢性能,在1.0 mol L^(-1)KOH和1.0 mol L^(-1)KOH+0.5 mol L^(-1)NaCl条件下,分别需要107和133 mV的过电位达到10 mA cm^(-2)的电流密度。

关键词：析氢反应纳米结构过渡金属磷化物耐氯腐蚀盐水分解

Zeolitic imidazolate framework-8 as a nanoadsorbent for radon capture

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Nuclear Science and Techniques 2016年第1期27卷 37-43页

作者： Xiao-wa wa.g Ting Yan Jun wan Li-Feng Zhao yu Tu School of Radiation Medicine and Protection Medicine College of Soochow UniversitySuzhou 215123China School for Radiological and Interdisciplinary Sciences Suzhou 215123China Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions Suzhou 215123China Jiangsu Provincial Key Laboratory of Radiation Medicineand Protection Suzhou 215123China National Institute of Biological Sciences Beijing 102206China

The feasibility of adsorption and the adsorption behavior of radon on a nanomaterial-based zeolitic imidazolate framework-8(ZIF-8) adsorbent were *** canonical Monte Carlo simulation and four-channel low-background a/b measurement were performed to examine the adsorption kinetics of this adsorbent. Results demonstrated that ZIF-8 is a good adsorbent of ***, this adsorbent can be used to significantly reduce the hazardous effects of radon on occupational radiation workers.

关键词：纳米沸石吸附剂氡捕获咪唑蒙特卡罗模拟吸附行为吸附性能

青藏高原尕斯库勒盐湖可培养嗜盐耐盐微生物的群落结构与分离方法对比研究

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海洋与湖沼 2024年第4期55卷 916-930页

作者：马欣马想蓉朱德锐李轩领沈国平邢江娃青海大学医学院基础医学研究中心青海西宁810016

嗜盐耐盐微生物在生物医药、生物酶等领域有着重要的应用潜力。为更好地利用青藏高原的盐湖微生物资源,以青藏高原尕斯库勒盐湖为研究对象,借助Illumina MiSeq测序平台分析盐湖微生物的群落组成,并采用寡营养培养、富集培养和梯度稀释... 详细信息

嗜盐耐盐微生物在生物医药、生物酶等领域有着重要的应用潜力。为更好地利用青藏高原的盐湖微生物资源,以青藏高原尕斯库勒盐湖为研究对象,借助Illumina MiSeq测序平台分析盐湖微生物的群落组成,并采用寡营养培养、富集培养和梯度稀释等方法对嗜盐耐盐微生物进行大规模分离与培养。结果表明,高通量测序获得明确分类地位的细菌有30门50纲81目162科417属,古菌6门7纲9目15科39属。细菌优势属类群以矿生菌属(Fodinibius)和纤维单胞菌属(gracilimonas)为主。古菌优势属类群以盐红菌属(Halorubrum)为主;纯培养法共获得502株嗜盐耐盐微生物,其中嗜盐耐盐细菌472株,分布在4门5纲7目9科13属,优势属为芽孢杆菌属(Bacillus)和盐单胞菌属(Halomonas),其中巴纽尔斯菌(Balneolota)门Fodinibius属可培养细菌是首次从盐湖中分离得到;嗜盐古菌30株,分布在1门1纲1目3科5属,优势属为Halorubrum。对比不同培养条件下的分离结果发现,1/2 TSA培养基和1/2 RCA培养基更有利于嗜盐耐盐细菌的分离,最佳富集天数为7天和30天,稀释梯度10-1和10-2可与未稀释样本互为补充来增加可培养嗜盐耐盐细菌的多样性;1/102216E培养基更适合于古菌的分离,最佳富集天数为7天和14天,且样本不稀释分离效果更好。研究结果可为青藏高原盐湖可培养微生物的分离方案优化提供理论依据和数据支撑。

关键词：尕斯库勒盐湖嗜盐耐盐微生物分离培养生物多样性高盐环境

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