检索结果-南通市图书馆

Exploring the Lagged Correlation Between Baidu Index and Influenza-Like Illness-China,2014-2019

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2024年第26期6卷 629-634页

作者： xuan Han Jiao Yang Yan Luo Dazhu Huo Xuya yu xuancheng Hu Ling Xin Liuyang Yang Hualei Xin Ting Zhang Zhongjie Li Weizhong Yang School of Population Medicine and Public Health Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical CollegeBeijingChina School of Health Policy and Management Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina Department of management science and information system Faculty of Management and EconomicsKunming University of Science and TechnologyKunming CityYunnan ProvinceChina

Introduction:This study investigated the lagged correlation between Baidu Index for influenza-related keywords and influenza-like illness percentage(ILI%)across regions in *** aim is to establish a scientific foundation for utilizing Baidu Index as an early warning tool for influenza-like illness ***:In this study,data on ILI%and Baidu Index were collected from 30 provincial-level administrative divisions(PLADs)spanning April 2014 to March *** Baidu Index was categorized into Overall Index,Ordinary Index,Prevention Index,Symptom Index,and Treatment Index based on search query *** lagged correlation between the Baidu Index and ILI%was examined through the cross-correlation function(CCF)***:Correlating the Baidu Overall Index of 30 PLADs with ILI%revealed CCF values ranging from 0.46 to 0.86,with a median lag of 0.5 *** analysis indicated that the Prevention Index and Symptom Index exhibited quicker responses to ILI%,with median lags of−9 and−0.5 days,respectively,compared to 0 and 3 days for the Ordinary and Treatment *** median lag days between the Baidu Index and the ILI%were earlier in the northern PLADs compared to the southern ***:The Prevention and Symptom Indexes show promising predictive capabilities for influenzalike illness epidemics.

关键词： utilizing illness Baidu

Human CD56+CD39+ dNK cells support fetal survival through controlling trophoblastic cell fate:immune mechanisms of recurrent early pregnancy loss

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

National Science Review 2024年第6期11卷 129-145页

作者： Wentong Jia Liyang Ma Xin yu Feiyang Wang Qian Yang Xiaoye Wang Mengjie Fan Yan Gu Ran Meng Jian Wang yuxia Li Rong Li xuan Shao Yan-Ling Wang State Key Laboratory of Stem cell and Reproductive Biology Key Laboratory of Organ Regeneration and ReconstructionInstitute of ZoologyChinese Academy of Sciences Beijing Institute for Stem Cell and Regenerative Medicine University of the Chinese Academy of Sciences NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drug and Devices Shanghai Institute for Biomedical and Pharmaceutical Technologies National Clinical Center for Obstetrics and Gynecology Peking University Third Hospital Department of Family Planning The Second Hospital of Tianjin Medical University Department of Prenatal Screening Haidian Maternal and Child Health Hospital

Decidual natural killer（dNK） cells are the most abundant immune cells at the maternal-fetal interface during early pregnancy in both mice and humans, and emerging single-cell transcriptomic studies have uncovered various human dNK subsets that are disrupted in patients experiencing recurrent early pregnancy loss（RPL） at early gestational stage, suggesting a connection between abnormal proportions or characteristics of dNK subsets and RPL pathogenesis. However, the functional mechanisms underlying this association remain unclear. Here, we established a mouse model by adoptively transferring human dNK cells into pregnant NOG（NOD/Shi-scid/IL-2Rγnull） mice, where human dNK cells predominantly homed into the uteri of recipients. Using this model, we observed a strong correlation between the properties of human dNK cells and pregnancy outcome. The transfer of dNK cells from RPL patients（dNK-RPL）remarkably worsened early pregnancy loss and impaired placental trophoblast cell differentiation in the recipients. These adverse effects were effectively reversed by transferring CD56+CD39+dNK *** studies revealed that CD56+CD39+dNK subset facilitates early differentiation of mouse trophoblast stem cells（m TSCs） towards both invasive and syncytial pathways through secreting macrophage colony-stimulating factor（M-CSF）. Administration of recombinant M-CSF to NOG mice transferred with dNK-RPL efficiently rescued the exacerbated pregnancy outcomes and fetal/placental development. Collectively, this study established a novel humanized mouse model featuring functional human dNK cells homing into the uteri of recipients and uncovered the pivotal role of M-CSF in fetal-supporting function of CD56+CD39+dNK cells during early pregnancy, highlighting that M-CSF may be a previously unappreciated therapeutic target for intervening RPL.

关键词： recurrent pregnancy loss CD56+CD39+ dNK subset NOG mice adoptive transfer placental trophoblast cell fate M-CSF

Population size estimates based on GPS telemetry

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Zoological Research 2024年第1期45卷 36-38页

作者： yu-xuan Fan Pu-Zheng Xie Chi Ma Ting Chen Xiao Ye Hua-Lin Xu Qiong Yang Peng-Fei Fan School of Life Sciences Sun Yat-sen UniversityGuangzhouGuangdong 510275China College of Agriculture and Biological Sciences DaliYunnan 671003China Neilingding-Futian National Nature Reserve of Guangdong ShenzhenGuangdong 518040China

DEAR EDITOR,Accurate estimation of population size is a crucial issue in wildlife population ecology and *** Global Positioning System(GPS)collars are well recognized as an effective method for monitoring wildlife behavior,their application in direct wildlife population size estimation remains *** this study,GPS telemetry was employed to survey a rhesus macaque(Macaca mulatta)population on Neilingding Island in Guangdong,*** May 2021 to April 2022,32 macaques across nine groups were fitted with GPS collars,producing a dataset of 109739 location *** data from all tracked individuals revealed the annual home ranges of the nine groups.

关键词： China Island size

Plant diversity increases diversity and network complexity rather than alters community assembly processes of leaf-associated fungi in a subtropical forest

在线全文

学校读者我要写书评

暂无评论

Science China Life Sciences 2024年

作者： Jie Li Xing-Chun Li Hui-yun Gan yue Zhang Zi-xuan Guo yu-xuan Liu Yong-Qing Lin Liang-Dong Guo State Key Laboratory of Mycology Institute of Microbiology Chinese Academy of Sciences College of Life Sciences University of Chinese Academy of Sciences

Plant diversity significantly impacts ecosystem processes and functions, yet its influence on the community assembly of leaf fungi remains poorly understood. In this study, we investigated leaf epiphytic and endophytic fungal communities in a Chinese subtropical tree species richness experiment, ranging from 1 to 16 species, using amplicon sequencing to target the internal transcribed spacer 1 region of the rDNA. We found that the community assembly of epiphytic and endophytic fungi was predominantly governed by stochastic processes, with a higher contribution of dispersal limitation on epiphytic than on endophytic fungal communities but a higher contribution of selection on endophytic than on epiphytic fungal communities. The plant-epiphytic fungus interaction network was more complex(e.g., more highly connected and strongly nested but less specialized and modularized) than the plant-endophytic fungus interaction network. Additionally,tree species richness was positively correlated with the network complexity and diversity of epiphytic(α-, β-and γ-diversity) and endophytic(β-and γ-diversity) fungi, but was not associated with the contribution of the stochastic and deterministic processes on the community assembly of epiphytic and endophytic fungi. This study highlights that tree species diversity enhances the diversity and network complexity,rather than alters the ecological processes in community assembly of leaf-associated fungi.

关键词：

Adjuvant postbiotic administration improves dental caries prognosis by restoring the oral microbiota

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第5期13卷 2690-2702页

作者： Qing Liu Teng Ma Cuijiao Feng Yalin Li Hao Jin xuan Shi Lai-yu Kwok Yan Shi Tingtao Chen Heping Zhang Affiliated Stomatological Hospital of Nanchang University Nanchang 330000China Department of Endodontics Affiliated Stomatological Hospital of Nanchang UniversityThe Key Laboratory of Oral Biomedicine of Jiangxi ProvinceJiangxi Province Clinical Research Center for Oral DiseasesNanchang 330000China Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering Inner Mongolia Agricultural UniversityHohhot 010000China Key Laboratory of Dairy Products Processing Ministry of Agriculture and Rural AffairsInner Mongolia Agricultural UniversityHohhot 010000China Key Laboratory of Dairy Biotechnology and Engineering Ministry of EducationInner Mongolia Agricultural UniversityHohhot 010000China National Engineering Research Center for Bioengineering Drugs and the Technologies Institute of Translational MedicineNanchang UniversityNanchang 330000China

Conventional filling therapy fails to fundamentally reduce oral cariogenic ***,oral microbiota follow-up intervention after filling would be necessary for improving dental caries *** recruited 9 caries-free individuals,and 89 dental caries subjects(5 dropouts).Eighty-nine patients were randomized into three groups:caries(n=8;no treatment),control(n=40;filling),and postbiotics(n=41;filling and 14-day Probio-Eco®intervention).Salivary samples were collected at 0 day(after filling)and 14 *** results showed that the diversity of dental caries oral microbiota was significantly increased compared with healthy subjects,and filling could restore a healthier oral microbiota partially and *** intervention keeps a low ***-occurrence network analysis showed that a more stable oral microbiota structure after postbiotics *** and functional annotation of the microbiota revealed that postbiotics co-treatment significantly:increased the relative abundance of Pseudomonas and ***,decreased the relative abundance of Prevotella shahii,and enriched the energy metabolism-related ***-predicted phenotypes inferred to an oral microbiota with decreased potential pathogenic bacteria and increased oxidative stress-tolerant bacteria after postbiotics ***,it suggested that postbiotics co-treatment could be a promising strategy that restores the oral microecological balance for dental caries.

关键词： Postbiotics Oral microbiota Salivary microbiota Dental caries Pacific Biosciences(PacBio)single molecule real-time(SMRT)sequencing Dental filling

Evolution of mechanical properties,localized corrosion resistance and microstructure of a high purity Al-Zn-Mg-Cu alloy during non-isothermal aging

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2024年第6期31卷 1790-1807页

作者： DAI xuan-xuan LI yu-zhang LIU Sheng-dan YE Ling-ying BAO Chong-jun School of Materials Science and Engineering Central South UniversityChangsha 410083China Key Laboratory of Lightweight and High-strength Structural Materials Changsha 410083China Key Laboratory of Non-ferrous Metals Science and Engineering(Ministry of Education) Changsha 410083China Kunming Metallurgical Research Institute Co. Ltd.Kunming 650031China

The evolution of mechanical properties,localized corrosion resistance of a high purity Al-Zn-Mg-Cu alloy during non-isothermal aging(NIA)was investigated by hardness test,electrical conductivity test,tensile test,intergranular corrosion test,exfoliation corrosion test,slow strain rate tensile test and electrochemical test,and the mechanism has been discussed based on microstructure examination by optical microscopy,electron back scattered diffraction,scanning electron microscopy and scanning transmission electron *** NIA treatment includes a heating stage from 40℃to 180℃with a rate of 20℃/h and a cooling stage from 180℃to 40℃with a rate of 10℃/*** results show that the hardness and strength increase rapidly during the heating stage of NIA since the increasing temperature favors the nucleation and the growth of strengthening precipitates and promotes the transformation of Guinier-Preston(GPI)zones toη'*** the cooling stage,the sizes ofη'phase increase with a little change in the number density,leading to a further slight increase of the hardness and *** NIA proceeds,the corroded morphology in the alloy changes from a layering feature to a wavy feature,the maximum corrosion depth decreases,and the reason has been analyzed based on the microstructural and microchemical feature of precipitates at grain boundaries and subgrain boundaries.

关键词： Al-Zn-Mg-Cu alloy non-isothermal aging mechanical properties localized corrosion resistance microstructure

Expression and clinical significance of short-chain fatty acids in patients with intrahepatic cholestasis of pregnancy

在线全文

学校读者我要写书评

暂无评论

World Journal of Hepatology 2024年第4期16卷 601-611页

作者： Shuai-Jun Ren Jia-Ting Feng Ting Xiang Cai-Lian Liao yu-Ping Zhou Rong-Rong xuan Department of Obstetrics and Gynecology The First Affiliated Hospital of Ningbo UniversityNingbo 315100Zhejiang ProvinceChina Health Science Center Ningbo UniversityNingbo 315211Zhejiang ProvinceChina Department of Gastroenterology The First Affiliated Hospital of Ningbo UniversityNingbo 315211Zhejiang ProvinceChina Institute of Digestive Disease Ningbo UniversityNingbo 315020Zhejiang ProvinceChina

BACKGROUND Intrahepatic cholestasis of pregnancy(ICP)is a pregnancy-specific liver condition that typically arises in the middle and late stages of ***-chain fatty acids(SCFAs),prominent metabolites of the gut microbiota,have significant connections with various pregnancy complications,and some SCFAs hold potential for treating such ***,the metabolic profile of SCFAs in patients with ICP remains *** To investigate the metabolic profiles and differences in SCFAs present in the maternal and cord blood of patients with ICP and determine the clinical significance of these *** Maternal serum and cord blood samples were collected from both patients with ICP(ICP group)and normal pregnant women(NP group).Targeted metabolomics was used to assess the SCFA levels in these *** Significant differences in maternal SCFAs were observed between the ICP and NP *** SCFAs exhibited a consistent declining trend in cord blood samples from the ICP group,mirroring the pattern seen in maternal *** analysis revealed a positive correlation between maternal serum SCFAs and cord blood SCFAs[r(Pearson)=0.88,P=7.93e-95].In both maternal serum and cord blood,acetic and caproic acids were identified as key metabolites contributing to the differences in SCFAs between the two groups(variable importance for the projection>1).Receiver operating characteristic analysis demonstrated that multiple SCFAs in maternal blood have excellent diagnostic capabilities for ICP,with caproic acid exhibiting the highest diagnostic efficacy(area under the curve=0.97).CONCLUSION Compared with the NP group,significant alterations were observed in the SCFAs of maternal serum and cord blood in the ICP group,although they displayed distinct patterns of ***,the SCFA levels in maternal serum and cord blood were significantly positively ***,certain maternal serum SCFAs,specifically caproic and acetic acids,demonst

关键词： Intrahepatic cholestasis of pregnancy Short-chain fatty acids Maternal serum Cord blood Caproic acid

Synergistic Impacts of Indian Ocean SST and Indo-China Peninsula Soil Moisture on the 2020 Record-breaking Mei-yu

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Atmospheric Sciences 2024年第9期41卷 1735-1750页

作者： Yinshuo DONG Haishan CHEN xuan DONG Wenjian HUA Wenjun ZHANG Key Laboratory of Meteorological Disaster Ministry of Education/Joint International Research Laboratory of Climate and Environment Change/Collaborative Innovation Center on Forecast and Evaluation of Meteorological DisastersNanjing University of Information Science and TechnologyNanjing 210044China School of Atmospheric Sciences Nanjing University of Information Science and TechnologyNanjing 210044China Bureau of Hydrology ChangJiang Water Resources CommissionWuhan 430010China

The Yangtze River basin(YRB)experienced a record-breaking mei-yu season in June‒July *** unique long-lasting extreme event and its origin have attracted considerable *** studies have suggested that the Indian Ocean(IO)SST forcing and soil moisture anomaly over the Indochina Peninsula(ICP)were responsible for this unexpected ***,the relative contributions of IO SST and ICP soil moisture to the 2020 mei-yu rainfall event,especially their linkage with atmospheric circulation changes,remain *** using observations and numerical simulations,this study examines the synergistic impacts of IO SST and ICP soil moisture on the extreme mei-yu in *** show that the prolonged dry soil moisture led to a warmer surface over the ICP in May under strong IO SST *** intensification of the warm condition further magnified the land thermal effects,which in turn facilitated the westward extension of the western North Pacific subtropical high(WNPSH)in June‒*** intensified WNPSH amplified the water vapor convergence and ascending motion over the YRB,thereby contributing to the 2020 *** contrast,the land thermal anomalies diminish during normal IO SST backgrounds due to the limited persistence of soil *** roles of IO SST and ICP soil moisture are verified and quantified using the Community Earth System *** synergistic impacts yield a notable 32%increase in YRB *** findings provide evidence for the combined influences of IO SST forcing and ICP soil moisture variability on the occurrence of the 2020 super mei-yu.

关键词： super mei-yu Indian Ocean SST soil moisture Indochina Peninsula

Comparison Between Threshold Method and Artificial Intelligence Approaches for Early Warning of Respiratory Infectious Diseases-Weifang City,Shandong Province,China,2020-2023

在线全文

学校读者我要写书评

暂无评论

China CDC weekly 2024年第26期6卷 635-641,I0010,I0011页

作者： Ting Zhang Liuyang Yang Ziliang Fan xuancheng Hu Jiao Yang Yan Luo Dazhu Huo Xuya yu Ling Xin xuan Han Jie Shan Zhongjie Li Weizhong Yang School of Population Medicine and Public Health Chinese Academy of Medical Sciences(CAMS)&Peking Union Medical College(PUMC)BeijingChina State Key Laboratory of Respiratory Health and Multimorbidity BeijingChina Key Laboratory of Pathogen Infection Prevention and Control(Peking Union Medical College) Ministry of EducationBeijingChina The Third Affiliated Hospital of Kunming Medical University Yunnan Cancer HospitalKunming CityYunnan ProvinceChina School of Data Science Fudan UniversityShanghaiChina Weifang Center for Disease Control and Prevention Weifang CityShandong ProvinceChina School of Health Policy and Management Chinese Academy of Medical Sciences&Peking Union Medical CollegeBeijingChina

Introduction:Respiratory infectious diseases,such as influenza and coronavirus disease 2019(COVID-19),present significant global public health *** emergence of artificial intelligence(AI)and big data offers opportunities to improve traditional disease surveillance and early warning ***:The study analyzed data from January 2020 to May 2023,comprising influenza-like illness(ILI)statistics,Baidu index,and clinical data from *** methodologies were evaluated:the adaptive dynamic threshold method(ADTM)for dynamic threshold adjustments,the machine learning supervised method(MLSM),and the machine learning unsupervised method(MLUM)utilizing anomaly *** comparison focused on sensitivity,specificity,timeliness,and warning ***:ADTM issued 37 warnings with a sensitivity of 71%and a specificity of 85%.MLSM generated 35 warnings,with a sensitivity of 82%and a specificity of 87%.MLUM produced 63 warnings with a sensitivity of 100%and specificity of 80%.The initial warnings from ADTM and MLUM preceded those from MLSM by five *** Kappa coefficient indicated moderate agreement between the methods,with values ranging from 0.52 to 0.62(P<0.05).Discussion:The study explores the comparison between traditional methods and two machine learning approaches for early warning *** emphasizes the validation of machine learning’s reliability and underscores the unique advantages of each ***,it stresses the significance of integrating machine learning models with various data sources to enhance public health preparedness and response,alongside acknowledging limitations and the need for broader validation.

关键词： specificity integrating utilizing