检索结果-南通市图书馆

Different effects of 24 dietary intakes on gastroesophageal reflux disease: A mendelian randomization

World Journal of Clinical Cases 2024年第14期12卷 2370-2381页

作者： yu-xin liu Wen-Tao Yang Yang Li Department of Oncology Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Cardiovascular Chengdu Integrated TCM&Western Medicine HospitalChengdu 610041Sichuan ProvinceChina Department of Nuclear Medicine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina

BACKGROUND In observational studies,dietary intakes are associated with gastroesophageal re-flux disease(GERD).AIM To conduct a two-sample mendelian randomization(MR)analysis to determine whether those associations are *** To explore the relationship between dietary intake and the risk of GERD,we extracted appropriate single nucleotide polymorphisms from genome-wide asso-ciation study data on 24 dietary *** methods were adopted for data analysis:Inverse variance weighting,weighted median methods,and MR-Egger's *** odds ratio(OR)and 95%confidence interval(CI)were used to eva-luate the causal association between dietary intake and *** Our univariate Mendelian randomization(UVMR)results showed significant evidence that pork intake(OR,2.83;95%CI:1.76-4.55;P=1.84×10–5),beer intake(OR,2.70,95%CI:2.00-3.64;P=6.54×10–11),non-oily fish intake(OR,2.41;95%CI:1.49-3.91;P=3.59×10–4)have a protective effect on *** addition,dried fruit intake(OR,0.37;95%CI:0.27-0.50;6.27×10–11),red wine intake(OR,0.34;95%CI:0.25-0.47;P=1.90×10-11),cheese intake(OR,0.46;95%CI:0.39-0.55;P=3.73×10-19),bread intake(OR,0.72;95%CI:0.56-0.92;P=0.0009)and cereal intake(OR,0.45;95%CI:0.36-0.57;P=2.07×10-11)were negatively associated with the risk of *** was a suggestive asso-ciation for genetically predicted coffee intake(OR per one SD increase,1.22,95%CI:1.03-1.44;P=0.019).Multi-variate Mendelian randomization further confirmed that dried fruit intake,red wine intake,cheese intake,and cereal intake directly affected *** contrast,the impact of pork intake,beer intake,non-oily fish intake,and bread intake on GERD was partly driven by the common risk factors for ***,after adjusting for all four elements,there was no longer a suggestive association between coffee intake and *** This study provides MR evidence to support the causal relationship between a broad range of dietary intake and GERD,providing new insights for the treatment and p

关键词： Dietary Gastroesophageal reflux disease Mendelian randomization Disease management Randomized controlled trial

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Socioeconomic traits and the risk of Barrett’s esophagus and gastroesophageal reflux disease: A Mendelian randomization study

引用

World Journal of Gastrointestinal Oncology 2024年第6期16卷 2631-2645页

作者： yu-xin liu Cheng-Li Bin Lu Zhang Wen-Tao Yang Bai-Ping An Department of Oncology Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Gynecology and Obstetrics Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Endocrine Hospital of Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Cardiovascular Chengdu Integrated TCM&Western Medicine HospitalChengdu 610041Sichuan ProvinceChina

BACKGROUND Previous observational studies have shown that the prevalence of gastroesophageal reflux disease(GERD)and Barrett’s esophagus(BE)is associated with socioeconomic ***,due to the methodological limitations of traditional observational studies,it is challenging to definitively establish *** To explore the causal relationship between the prevalence of these conditions and socioeconomic status using Mendelian randomization(MR).METHODS We initially screened single nucleotide polymorphisms(SNPs)to serve as proxies for eight socioeconomic status phenotypes for univariate MR *** inverse variance weighted(IVW)method was used as the primary analytical method to estimate the causal relationship between the eight socioeconomic status phenotypes and the risk of GERD and *** then collected combinations of SNPs as composite proxies for the eight socioeconomic phenotypes to perform multivariate MR(MVMR)analyses based on the IVW MVMR ***,a two-step MR mediation analysis was used to examine the potential mediation of the associations by body mass index,major depressive disorder(MDD),smoking,alcohol consumption,and sleep *** The study identified three socioeconomic statuses that had a significant impact on *** included household income[odds ratio(OR):0.46;95% confidence interval(95%CI):0.31-0.70],education attainment(OR:0.23;95%CI:0.18-0.29),and the Townsend Deprivation Index at recruitment(OR:1.57;95%CI:1.04-2.37).These factors were found to independently and predominantly influence the genetic causal effect of ***,the mediating effect of educational attainment on GERD was found to be mediated by MDD(proportion mediated:10.83%).Similarly,the effect of educational attainment on BE was mediated by MDD(proportion mediated:10.58%)and the number of cigarettes smoked per day(proportion mediated:3.50%).Additionally,the mediating effect of household income on GERD was observed to be mediated by sleep dur

关键词： Socioeconomic status Gastroesophageal reflux disease Barrett’s esophagus Two-step Mendelian randomization Multivariate Mendelian randomization

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The pseudoscalar meson and baryon octet interaction with strangeness S=-2 in the unitary coupled-channel approximation

引用

Communications in Theoretical Physics 2022年第7期74卷 99-104页

作者： Bao-Xi Sun xin-yu liu Faculty of Science Beijing University of TechnologyBeijing 100124China

The interaction of the pseudo scalar meson and the b ary on octet with strangeness S=-2 and isospin I=1/2 is investigated by solving the Bethe-Salpeter equation in the infinite and finite volume *** is found that there is a resonance state generated dynamically,which owns a mass of about 1550 MeV and a large decay width of 120-200 *** resonance state couples strongly to theπΞ***,it might not correspond to theΞ(1620)particle announced by Belle *** the same time,this problem is studied in the finite volume,and an energy level at 1570 MeV is obtained,which is between theπΞand KΛthresholds and independent of the cubic box size.

关键词： Bethe-Salpeter equation chiral unitary approach amplitude

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

单一分子量含氟嵌段共聚物的本体及薄膜自组装研究

引用

高分子学报 2024年第2期55卷 142-152页

作者：吴海兵蒋胜喜谭睿刘雨欣董学会张正彪苏州大学材料与化学化工学部苏州215123 华南理工大学前沿软物质学院广州510640

嵌段共聚物导向自组装作为一种自下而上的图案化工艺,受到工业界和学术界的广泛关注.然而,导向自组装中缺陷率与分子参数之间的关系研究尚不清晰.本文工作基于模块化合成策略,利用迭代指数增长法并结合巯基-双键的点击反应成功制备了高... 详细信息

嵌段共聚物导向自组装作为一种自下而上的图案化工艺,受到工业界和学术界的广泛关注.然而,导向自组装中缺陷率与分子参数之间的关系研究尚不清晰.本文工作基于模块化合成策略,利用迭代指数增长法并结合巯基-双键的点击反应成功制备了高χ低N的单一分子量含氟聚酯嵌段共聚物(oLAn-FPOSS).单一分子量特征可以排除多分散性对自组装行为的影响.本体自组装研究表明聚酯嵌段和含氟嵌段具有强相分离驱动力,可以形成特征尺寸小于10 nm的六方柱状相结构(HEX).在薄膜自组装中,嵌段共聚物经过简单的热退火可以在硅片表面形成平行基底排布的柱状纳米图案.此外,通过对比研究不同链长单一分子量嵌段共聚物的薄膜组装行为,发现随着嵌段共聚物链长的增长薄膜组装图形缺陷率明显下降,初步揭示了薄膜自组装过程中缺陷形成对嵌段共聚物链长的依赖性.

关键词：单一分子量高分子导向自组装含氟嵌段共聚物本体及薄膜自组装光刻

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Control Aggregation of P3HT in Solution for High Efficiency Doping:Ensuring Structural Order and the Distribution of Dopants

引用

Chinese Journal of Polymer Science 2023年第5期41卷 811-823,I0012页

作者： Duo liu Jun-Hang Li Si-Chun Wang Lu Zhang xin-yu liu Qiang Zhang Yan-Chun Han State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China

Molecular doping is one of the most important tools to manipulate the electrical properties of conjugated polymers for application in organic *** polymer crystallinity and distribution position of the dopant crucially determine electrical conductivity of the doped ***,in solution-mixed doping,the interplay between polymer and dopant leads to highly structural disorder of polymer and random arrangement of ***,we propose a strategy to ensure the dopant induced polarons have high charge dissociation and transport by letting the conjugated polymers aggregate in the marginal solvent solution by cooling it from higher temperature to room *** select poly(3-hexylthiophene-2,5-diyl)(P3HT)solution doped by 2,3,5,6-tetrafluoro-7,7,8,8-tetracyanoquinodimethane(F4TCNQ)as a model system.P3HT crystallizes in the marginal solvent,such as 1,1,2-trichloroethane(TCE)driven by the favorπ-πinteraction between planar polymer *** dopant F4TCNQ enters the alkyl side chain region not theπ-πstacking region and thus guarantees high crystallinity and theπ-πinteraction of *** distribution of F4TCNQ which away from the polymer backbone to ensure higher charge dissociation and ***,we obtained a high conductivity value of 23 S/cm by doping P3HT with 20%F4TCNQ by using the marginal solvent,which is higher than doping P3HT with a disordered coil conformation in chlorobenzene(CB)of 7 S/cm,which the dopants enter both the alkyl side chain region and theπ-πstacking region.

关键词： Solvent Crystalline Dopant location Doping efficiency Electrical conductivity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

双层壁涡轮叶片短径扇形气膜孔冷却性能数值研究

引用

风机技术 2024年第3期66卷 1-7页

作者：刘新宇王建华浦健姚然中国科学技术大学工程科学学院中国科学院工程热物理研究所

针对高冷效双层壁涡轮叶片表面应用短径扇形孔设计准则及强化气膜冷却,机理依旧不明的现状,本文利用流固弱耦合数值模拟技术研究了典型7-7-7和11-11-11扇形气膜孔应用于双层壁涡轮叶片设计的冷却特性。在宽范围吹风比下(0.6~2.4),比较... 详细信息

针对高冷效双层壁涡轮叶片表面应用短径扇形孔设计准则及强化气膜冷却,机理依旧不明的现状,本文利用流固弱耦合数值模拟技术研究了典型7-7-7和11-11-11扇形气膜孔应用于双层壁涡轮叶片设计的冷却特性。在宽范围吹风比下(0.6~2.4),比较了三种扇形气膜孔布置方案,包含叶片两侧同构布局7-7-7孔(简称SH1布局)和11-11-11孔(简称SH2布局)及新提出的异构布局(简称SH3布局),并以常规圆形孔作为比较依据。通过数值结果对比指出:在双层壁表面应用扇形孔代替圆形孔,最低可提升吸力面综合冷却效率17%,压力面7%。然而,扇形孔也会诱导两侧冷却性能差异扩大的现象。应用两侧孔型异构布局,要求在压力侧布置相较于吸力侧各向扩张角更大的扇形孔,可以有效改善叶片内部的流量配置,从而在提升综合冷却效率的基础上兼顾两侧温差缩小。在高吹风比条件下,上述异构诱发的冷却优势更为显著。但相对吸力侧、压力侧对扇形孔型结构参数的敏感性更大。因此,压力侧的异型孔气膜冷却挑战性更大。

关键词：双层壁冷却叶片短径扇形孔气膜冷却异构布局流固耦合传热

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

Treatment strategy on traumatic mid-lumbar spondyloptosis with concomitant multiple injuries:A case report and literature review

引用

Chinese Journal of Traumatology 2023年第1期26卷 33-40页

作者： Lin Cheng Cheng Qiu xin-yu liu Xi-Guang Sang Department of Emergency Medicine Qilu Hospital of Shandong UniversityJinan250012China Department of Orthopaedic Surgery Qilu Hospital of Shandong UniversityJinan250012China Cheeloo College of Medicine Shandong UniversityJinan250012China

Spondyloptosis in the clinic is rarely *** herein present a 47-year-old female,who suffered from a crush injury directly by a heavy cylindrical object from the lateral *** was diagnosed to have traumatic L3 spondyloptosis with multiple *** surgical procedures were conducted and a three-year follow-up was ***,normal spinal alignment was restored,and neurological deficits were gradually *** three years follow-up,the motor strength scores and function of the sphincters were incompletely *** published reports on traumatic lumbar spondyloptosis were reviewed and several critical points for management of this severe type of spinal injury were ***,thoracolumbar and lumbosacral junction were mostly predilection ***,numerous patients involving traumatic lumbar spondyloptosis were achieved to American Spinal Injury Association grade ***,lumbar spondyloptosis was commonly coupling withcauda equina ***,the outcomes were still with poorly prognosis and recovery of patients was correlation to spondyloptosis *** on this case report and literatures review,we highlighted that the spinal alignment restoration relying on staged operations and following rehabilitation hereof are both important once facing with multiple ***,we suggested to perform routine CT angiography during lumbar spondyloptosis to justify whether there are large vessel compression or injury.

关键词： Spondyloptosis Multiple trauma Fracture dislocation American Spinal Injury Association Lumbar spine

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Numerical investigations of the interactions between bubble induced shock waves and particle based on OpenFOAM

引用

Journal of Hydrodynamics 2024年第2期36卷 355-362页

作者： Jia-xin yu Jin-sen Hu yu-hang liu Yi-fan liu Dan Gao yu-ning Zhang Key Laboratory of Power Station Energy Transfer Conversion and System Ministry of EducationSchool of Energy Power and Mechanical EngineeringNorth China Electric Power UniversityBeijing102206China

The presence of particles and the shock waves generated by the cavitation bubbles can significantly affect the safety and the performance of hydrodynamic *** the present paper,the shock waves generated by cavitation bubble collapsing near the particle are numerically investigated based on the OpenFOAM together with the numerical schlieren for the shock wave *** numerical results reveal that the stand-off distance is one of the paramount factors affecting the interactions between the particle and the shock *** different kinds of shock waves(e.g.,bubble-inception,jet formation,particle reflected and jet-split shock waves)are observed during the bubble collapsing near the *** stand-off distance smaller than 0.5 or larger than 1.1,the maximum pressure at particle surface generated by the bubble growth can surpass those of the collapse stage.

关键词： Particle-bubble interaction shockwaves jetdynamics

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Controllable nucleation and deformation of skyrmions on surface of magnetic nanotubular monolayer

引用

Rare Metals 2024年第7期43卷 3250-3259页

作者： xin-xin Zhang Chen-yu Zhang Yi-xin xing Chao Man Jiao liu Yong Hu Department of Physics College of SciencesNortheastern University School of Materials and Mineral Resources Engineering Universiti Sains MalaysiaEngineering Campus State Key Laboratory of Rolling and Automation Northeastern University

Magnetic skyrmions emerge when the energy of ferromagnetic exchange interaction promoting parallel alignment of spins enters in competition with energies favoring non-collinear alignment of spins such as Dzy aloshinskii-Moriya interaction(DMI),long-rang dipole-dipole interaction(DDI),or higher-order exchange *** perform an unbiased Monte Carlo simulation to study the DMI-based skyrmion nucleation and stabilization on the surface of magnetic nanotubular monolayer controlled by tuning constants of DDI(g) and next-nearest-neighbor antiferromagnetic exchange interaction(j') with appropriate *** g and j',the loosely distributed skyrmions initially nucleate on the surface of nanotube approaching to the magnetic field(h) direction with increasing h in the intermediate ***,the skyrmion size,shape,density,distribution and crystal structure,as well as its driven field range,are tailored by g and j'.This work demonstrates the skyrmion nucleation mechanisms in three-dimensional magnetic nanostructures with curvature effect and multiple interactions,serving as a benchmark for a guide to experimentalists for preparation of samples in magnetic skyrmion states.

关键词： Magnetic nanotube Magnetic skyrmion Dzyaloshinskii–Moriya interaction Dipole–dipole interaction Monte Carlo simulation

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

二硫化钼和碳纳米管复合物电极用于盐差能转换

引用

电化学（中英文） 2024年第6期30卷 32-44页

作者：李家俊张伟彬刘鑫宇杨静蕾尹易杨泽钦马雪婧成都理工大学材料与化学化工学院四川成都610059

海洋占地球水资源总量的97%,地表面积的70%以上。随着化石燃料等不可再生能源的持续消耗与可再生能源的快速发展,人们对海洋资源的利用越来越重视。海洋能包括潮汐能、波浪能、温差能和盐差能等。其中盐差能是海水和淡水相互作用产生的... 详细信息

海洋占地球水资源总量的97%,地表面积的70%以上。随着化石燃料等不可再生能源的持续消耗与可再生能源的快速发展,人们对海洋资源的利用越来越重视。海洋能包括潮汐能、波浪能、温差能和盐差能等。其中盐差能是海水和淡水相互作用产生的能量,是以化学能形式存在的海洋能,这种能量较多产生在河口处。目前,压力延迟渗透技术、反电渗析技术和电容混合技术是转换盐差能的三种主要技术。本文构建了一种基于电容混合技术的新型盐差电池,使用二硫化钼和多壁碳纳米管复合物电极作为阳极,活性炭作为阴极。将两种不同离子储存机制的材料复合在一起,二硫化钼具有类似石墨烯的层状结构,层间间距约为石墨烯的两倍,是一种可以与钠离子发生插层反应的电池电极材料。多壁碳纳米管具有典型的双电层效应,放电时在其表面吸附钠离子的同时,可以帮助钠离子更快地进入二硫化钼层间,加快离子传输效率和盐差能的转换效率。对该复合材料进行物理和电化学表征,并与活性炭电极组装的盐差电池,测试其盐差能转换能力。浓度响应电压150 mV,经过一个完整的四步循环后,转换能量密度可达6.96 J·g^(-1)。该器件原材料价格较低,并且不使用离子膜,更加环保,为转换盐差能的研究提供了一种新途径。

关键词：盐差量电化学转化转换效率二硫化钼碳纳米管

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：