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Prognostic value of 11-factor modified frailty index in postoperative adverse outcomes of elderly gastric cancer patients in China

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1093-1103页

作者： Zi-Yao Xu xin-yu hao Di Wu Qi-Ying Song xin-xin Wang Department of General Surgery The First Medical Center of Chinese PLA General HospitalBeijing 100853China Department of Anesthesiology The First Medical Center of Chinese PLA General HospitalBeijing 100853China

BACKGROUND Preoperative evaluation of frailty is limited to a few surgical ***,the evaluation in Chinese elderly gastric cancer(GC)patients remains *** To validate and estimate the prognostic value of the 11-index modified frailty index(mFI-11)for predicting postoperative anastomotic fistula,intensive care unit(ICU)admission,and long-term survival in elderly patients(over 65 years of age)undergoing radical *** This study was a retrospective cohort study which included patients who underwent elective gastrectomy with D2 Lymph node dissection between April 1,2017 and April 1,*** primary outcome was 1-year all-cause *** secondary outcomes were admission to ICU,anastomotic fistula,and 6-mo *** were divided into two groups according to the optimal grouping cutoff of 0.27 points from previous studies:High risk of frailty marked as mFI-11High and low risk of frailty marked as *** curves between the two groups were compared,and univariate and multivariate regression analyses were performed to explore the relationship between preoperative frailty and postoperative complications in elderly patients undergoing radical *** discrimination ability of the mFI-11,prognostic nutritional index,and tumornode-metastasis pathological stage to identify adverse postoperative outcomes was assessed by calculating the area under the receiver operating characteristic(ROC)*** A total of 1003 patients were included,of which 13.86%(139/1003)were defined as having mFI-11High and 86.14%(864/1003)as having *** comparing the incidence of postoperative complications in the two groups of patients,it was found that mFI-11High patients had higher rates of 1-year postoperative mortality,admission to ICU,anastomotic fistula,and 6-mo mortality than the mFI-11Low group(18.0%vs 8.9%,P=0.001;31.7%vs 14.7%,P<0.001;7.9%vs 2.8%,P<0.001;and 12.2%vs 3.6%,P<0.001).Multivariate analysis revealed mFI-11 as an independent pr

关键词： Gastric cancer Frailty Mortality Anastomotic fistula Elderly

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The momentum distributions of triatomic molecular ion H_(3)^(2+) by intense laser pulses

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Communications in Theoretical Physics 2023年第6期75卷 112-119页

作者： Zhi-Xian Lei Shu-Juan Yan xin-yu hao Pan Ma Sheng-Peng Zhou Jing Guo Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China

We investigate theoretically the photoionization of triatomic molecular ion H_(3)^(2+) by numerically solving the two-dimensional time-dependent Schrödinger equations under Bohn-Oppenheimer *** results show that the photoelectron momentum distributions(PMDs)of H_(3)^(2+) with different initial states are strongly dependent on the laser ellipticities and molecular orbital symmetry,and the PMDs of degenerate electronic states E^(±)are mirror ***,for degenerate electronic states E^(±),vortex structures appear in the PMDs by the counter-rotating circularly polarized laser pulses as the time delay between the two pulses increases,which can be explained by multicenter ionization and ultrafast photoionization model.

关键词： momentum distribution ringlike molecules intense laser fields

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Photoelectron momentum distributions of triatomic CO_(2)molecules by circularly polarized attosecond pulses

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Chinese Physics B 2024年第10期33卷 220-225页

作者： Si-Qi Zhang Jun Zhang xin-yu hao Jing Guo Aihua Liu Xue-Shen Liu Institute of Atomic and Molecular Physics Jilin UniversityChangchun 130012China School of Physics Harbin Institute of TechnologyHarbin 150001China

Molecular-frame photoelectron momentum distributions(MF-PMDs)have been studied for imaging molecular *** investigate the MF-PMDs of CO_(2)molecules exposed to circularly polarized(CP)attosecond laser pulses bysolving the time-dependent Schrodinger equations based on the single-active-electron approximation *** showthat high-frequency photons lead to photoelectron diffraction patterns,indicating molecular *** diffractionpatterns can be illustrated by the ultrafast photoionization ***,for the driving pulses with 30 nm,a deviationbetween MF-PMDs and theoretically predicted results of the ultrafast photoionization models is produced because theCoulomb effect strongly influences the molecular ***,the MF-PMDs rotate in the same directionas the helicity of driving laser *** results also demonstrate that the MF-PMDs in a CP laser pulse are the superpositionof those in the parallel and perpendicular linearly polarized *** simulations efficiently visualize molecularorbital geometries and structures by ultrafast photoelectron ***,we determine the contribution of HOMOand HOMO-1 orbitals to ionization by varying the relative phase and the ratio of these two orbitals.

关键词： molecular-frame photoelectron momentum distributions single-active-electron approximation frames ultrafast photoionization models

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基于虚拟误差传感的大尺度空间有源降噪性能研究

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振动工程学报 2024年第4期37卷 677-685页

作者：代海陈克安李荣玉昊昕西北工业大学航海学院陕西西安710072 西安艾科特声学科技有限公司陕西西安710075

针对大尺度空间有源降噪系统误差传声器布放位置受限问题,本文使用虚拟误差传感在降噪目标区域放置多个虚拟误差传声器,将静音区由物理误差传声器点转移至虚拟误差传声器点,扩大降噪目标区域中静音区范围。为了对降噪性能及影响因素进... 详细信息

针对大尺度空间有源降噪系统误差传声器布放位置受限问题,本文使用虚拟误差传感在降噪目标区域放置多个虚拟误差传声器,将静音区由物理误差传声器点转移至虚拟误差传声器点,扩大降噪目标区域中静音区范围。为了对降噪性能及影响因素进行分析与研究,给出多通道虚拟误差传感的原理和算法,对降噪性能及物理与虚拟误差传声器的数量和布放等因素进行仿真分析,在飞机模型舱内进行实验验证。仿真及实验结果表明:使用虚拟误差传感有利于增大降噪目标区域降噪量及静音区;物理与虚拟误差传声器的布放影响静音区的分布;合理的物理与虚拟误差传声器数量及布放可以扩大静音区使其100%覆盖降噪目标区域,最优数量与初级声场频率特性相关。

关键词：有源噪声控制虚拟误差传感静音区空间降噪误差传声器

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水下圆柱壳声辐射有源力控制及机理分析

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振动工程学报 2014年第4期27卷 547-554页

作者：丁少虎陈克安马玺越玉昊昕西北工业大学航海学院陕西西安710072

研究了利用力激励进行水下有限长圆柱壳振动声辐射有源控制问题。考虑流固声振耦合作用,根据圆柱壳辐射声功率在周向相互解耦的特性,推导了次级力源最优强度解析表达式,比较了单个力和多个力有源控制后的降噪效果;利用圆柱壳结构振动模... 详细信息

研究了利用力激励进行水下有限长圆柱壳振动声辐射有源控制问题。考虑流固声振耦合作用,根据圆柱壳辐射声功率在周向相互解耦的特性,推导了次级力源最优强度解析表达式,比较了单个力和多个力有源控制后的降噪效果;利用圆柱壳结构振动模态和声辐射模态的对应关系,分析了圆柱壳声辐射有源力控制的物理机理。研究结果表明:多个次级力更能有效地控制壳体产生声辐射的振动部分而达到控制噪声的目的;水下圆柱壳的前几阶声辐射模态的辐射效率很高,而辐射模态幅度较低,有源控制机理在于降低与结构振动模态对应的声辐射模态幅度,从而有效控制结构振动产生的声辐射。

关键词：噪声有源控制水下圆柱壳声辐射模态振动模态

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PVDF阵列构建结构声辐射有源控制误差传感策略

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振动工程学报 2013年第5期26卷 797-806页

作者：马玺越陈克安玉昊昕丁少虎西北工业大学航海学院陕西西安710072

结构声有源控制是抑制低频声辐射的有效方案,误差传感策略是实现该系统需解决的问题。通过矩形小块PVDF阵列采集结构表面振动信息实现波数变换,在波数域构建传感策略实现误差信号的检测。首先对平板的振动响应建模,然后以波数域辐射声... 详细信息

结构声有源控制是抑制低频声辐射的有效方案,误差传感策略是实现该系统需解决的问题。通过矩形小块PVDF阵列采集结构表面振动信息实现波数变换,在波数域构建传感策略实现误差信号的检测。首先对平板的振动响应建模,然后以波数域辐射声功率为基础,通过对结构表面加速度或PVDF输出电荷作连续与离散波数变换来构建误差信号,实现误差传感策略。最后通过实例计算来验证误差传感方案的有效性,并给出其具体的实现步骤。结果表明,构建的误差信号与结构的辐射声功率信息相关性强,且用少量PVDF薄膜采样即可获得满意的降噪效果。

关键词：结构声辐射有源控制波数变换误差传感策略

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Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： xin Yang yu-Wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

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Gradient‑Layered MXene/Hollow Lignin Nanospheres Architecture Design for Flexible and Stretchable Supercapacitors

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Nano-Micro Letters 2025年第2期17卷 447-462页

作者： haonan Zhang Cheng hao Tongtong Fu Dian yu Jane Howe Kaiwen Chen Ning Yan hao Ren Huamin Zhai Jiangsu Provincial Key Lab of Sustainable Pulp and Paper Technology and Biomass Materials NanJing Forestry UniversityNanjing 210037People’s Republic of China Department of Chemical Engineering and Applied Chemistry University of Toronto200 College StreetTorontoON M5S 3E5Canada Department of Materials Science and Engineering University of Toronto184 College StreetTorontoON M5S 3E4Canada College of Materials Science and Engineering Nanjing Forestry UniversityNanjing 210037People’s Republic of China

With the rapid development of flexible wearable electronics,the demand for stretchable energy storage devices has *** this work,a novel gradient-layered architecture was design based on single-pore hollow lignin nanospheres(HLNPs)-intercalated two-dimensional transition metal carbide(Ti_(3)C_(2)T_(x) MXene)for fabricating highly stretchable and durable *** depositing and inserting HLNPs in the MXene layers with a bottom-up decreasing gradient,a multilayered porous MXene structure with smooth ion channels was constructed by reducing the overstacking of MXene ***,the micro-chamber architecture of thin-walled lignin nanospheres effectively extended the contact area between lignin and MXene to improve ion and electron accessibility,thus better utilizing the pseudocapacitive property of *** these strategies effectively enhanced the capacitive performance of the *** addition,HLNPs,which acted as a protective phase for MXene layer,enhanced mechanical properties of the wrinkled stretchable electrodes by releasing stress through slip and deformation during the stretch-release cycling and greatly improved the structural integrity and capacitive stability of the *** electrodes and symmetric flexible all-solid-state supercapacitors capable of enduring 600%uniaxial tensile strain were developed with high specific capacitances of 1273 mF cm^(−2)(241 F g^(−1))and 514 mF cm^(−2)(95 F g^(−1)),***,their capacitances were well preserved after 1000 times of 600%stretch-release *** study showcased new possibilities of incorporating biobased lignin nanospheres in energy storage devices to fabricate stretchable devices leveraging synergies among various two-dimensional nanomaterials.

关键词： Hollow lignin nanospheres MXene Gradient-layered architecture Wrinkled electrodes Stretchable supercapacitors

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Visible-light-responsive homologous heterostructure of oxynitrides constructed to boost charge separation and water splitting

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Science China Chemistry 2025年第01期 186-191页

作者： Hai Zou yunfeng Bao Xueshang xin yu Qi Tengfeng Xie Fuxiang Zhang State Key Laboratory of Catalysis Dalian National Laboratory for Clean Energy Dalian Institute of Chemical Physics Chinese Academy of Sciences School of Chemistry and Chemical Engineering Liaoning Normal University College of Chemistry Jilin University

Constructing type II heterostructures represents a widely recognized strategy for enhancing charge separation and photocatalytic efficiency,but it remains challenging to fabricate homologous heterostructures based on visible-light-responsive semiconductors,especially for popularly investigated （oxy）nitrides with low thermal ***,we synthesized a homologous heterostructure （denoted as YTON＿H） based on the oxynitrides of YTaO4-xNyand YTa *** heterostructure exhibits type II band structure alignment and intimate interface achieved through a magnesium （Mg） powder-assisted nitridation *** with widely reported heterologous heterostructures,the as-obtained YTON＿H homologous heterostructure could similarly exhibit enhanced charge separation as well as photocatalytic water splitting performance with respect to its counterparts(YTaO4-xNyand YTaON2).Meanwhile,detailed structural characterizations and spectroscopy analysis have been made to confirm the formation of heterostructure and promotion of spatial charge separation.

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无掺杂石墨碳封装Fe_(3)C纳米颗粒的制备及其氧还原性能

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Journal of Central South University 2023年第1期30卷 35-48页

作者：于鑫浩武军于巾媛王德强何佳艺胡静谷俐曹雪波 School of Materials Science and Engineering Changzhou UniversityChangzhou 213164China College of Advanced Materials Engineering Jiaxing Nanhu UniversityJiaxing 314001China School of Materials and Textile Engineering Jiaxing UniversityJiaxing 314001China School of Biological and Chemical Engineering Jiaxing UniversityJiaxing 314001China

近年来,含氮金属碳化物氧还原反应(ORR)催化剂被广泛报道,但受到Fe_(x)N、N_(x)C和Fe纳米颗粒等多种反应活性位点的干扰,Fe_(3)C在催化过程中的具体作用尚不清楚。本文以Fe_(2)O_(3)纳米微球和细菌纤维素(BC)为原料,经热解得到了一种Fe_... 详细信息

近年来,含氮金属碳化物氧还原反应(ORR)催化剂被广泛报道,但受到Fe_(x)N、N_(x)C和Fe纳米颗粒等多种反应活性位点的干扰,Fe_(3)C在催化过程中的具体作用尚不清楚。本文以Fe_(2)O_(3)纳米微球和细菌纤维素(BC)为原料,经热解得到了一种Fe_(3)C/C核壳催化剂。虽然被封装的无氮Fe_(3)C颗粒不接触电解液,但BC碳化后形成石墨层的ORR催化活性得到大幅提升。石墨层保护了内部碳化物,使其在酸性和碱性电解液中均表现出良好的催化活性和稳定性。该催化剂可作为理解此类无杂元素封装型催化剂ORR活性位点的模型系统。本文提出的碳化物催化剂及其作用机理为ORR催化剂的开发提供了新的思路。

关键词：碳化铁非贵金属电极催化剂纳米结构细菌纤维素氧还原反应

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