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SIZ1-mediated SUMOylation of CPSF100 promotes plant thermomorphogenesis by controlling alternative polyadenylation

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Molecular Plant 2024年第9期17卷 1392-1406页

作者： Zhibo yu Jun Wang Cheng Zhang Qiuna Zhan Leqian Shi Bing Song Danlu Han Jieming Jiang Junwen Huang Xiaolin Ou Zhonghui Zhang Jianbin lai Qingshun Quinn Li Chengwei Yang Guangdong Provincial Key Laboratory of Biotechnology for Plant Development School of Life ScienceSouth China Normal UniversityGuangzhou 510631China Key Laboratory of the Ministry of Education for Coastal and Wetland Ecosystems Cllege of the Environment and EcologyXiamen UniversityXiamenFujan 361102China Biomedical Science Division College of Dental MedicineWestern University of Health SciencesPomonaCA 91766USA

Under warm temperatures,plants adjust their morphologies for environmental adaption via precise gene expression ***,the function and regulation of alternative polyadenylation(APA),an important fine-tuning of gene expression,remains unknown in plant *** this study,we found that SUMOylation,a critical post-translational modification,is induced by a long-term treat-ment at warm temperatures via a SUMO ligase SIZ1 in *** of SIZ1 altered the global usage of polyadenylation signals and affected the APA dynamic of thermomorphogenesis-related ***100,a key subunit of the CPSF complex for polyadenylation regulation,is SUMOylated by ***,we demonstrated that SUMOylation is essential for the function of CPSF1oo in genome-wide polyadenylation site choice during *** analyses revealed that the SUMO conjugation on CPSF100 attenuates its interaction with two isoforms of its partner CPSF30,increasing the nuclear accumulation of CPsF1oo for polyadenylation *** summary,our study uncovers a regulatory mechanism of APA via SiZ1-mediated SUMOylation in plant thermomorpho-genesis.

关键词： alternative polyadenylation CPSF100 SiZ1 SUMOylation thermomorphogenesis

市域尺度上市企业数字化转型演变及对碳排放影响

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经济地理 2024年第5期44卷 106-116页

作者：张悦来逢波程钰山东师范大学地理与环境学院山东济南250358 潍坊学院经济管理学院山东潍坊261061

文章借助中国A股上市公司数据,利用数字化转型相关词频总和、数字资产占无形资产比重衡量企业数字化转型,运用Dagum基尼系数和空间杜宾模型等揭示了其时空特征及对城市碳排放量的作用机理。研究发现:(1)城市企业数字化转型整体稳步发展... 详细信息

文章借助中国A股上市公司数据,利用数字化转型相关词频总和、数字资产占无形资产比重衡量企业数字化转型,运用Dagum基尼系数和空间杜宾模型等揭示了其时空特征及对城市碳排放量的作用机理。研究发现:(1)城市企业数字化转型整体稳步发展,数字化转型相关词频总和从2011年的0.563万次增加至2021年的3.342万次,数字资产占无形资产比重相应从2.60%提升至4.64%。(2)胡焕庸线东部地区数字化转型水平高于西部地区,区域之间差距明显大于区域内部差距,其中西部地区内部差异最大。总体差异呈现减小趋势,空间集聚效应较弱但不断提升,加速向京津冀、长三角、珠三角等城市群集聚。(3)企业数字化转型对城市碳排放量存在显著抑制作用和空间溢出效应,主要通过企业内部与产业融合两个方面实现结构优化、资源整合、效率提升、效益增加和碳排减少,不同地区、不同经济聚集区域的碳减排效应具有异质性。文章从数字技术应用、适宜转型方式、长效激励机制、区域协调发展等方面提出对策建议,对促进数字化转型及降碳效应具有一定的借鉴参考意义。

关键词：上市企业数字化转型文本数据碳排放

基于CiteSpace的医学免疫学实验教学研究现状、热点及发展趋势的可视化分析

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中国免疫学杂志 2024年第6期40卷 1271-1275,1282页

作者：张会择赖宇成都中医药大学基础医学院成都611137

医学免疫学是连接基础医学和临床医学的重要桥梁课程,也是医学生基础医学理论学习中的重点和难点。医学免疫学实验可将基础知识进行系统串联,并融入学生实际操作、主动观察和积极思考的过程中,有助于学生系统地理解和掌握免疫学基本概... 详细信息

医学免疫学是连接基础医学和临床医学的重要桥梁课程,也是医学生基础医学理论学习中的重点和难点。医学免疫学实验可将基础知识进行系统串联,并融入学生实际操作、主动观察和积极思考的过程中,有助于学生系统地理解和掌握免疫学基本概念和原理。医学免疫学实验教学研究现状、热点及发展趋势已成为教师们关注的重点话题。本文通过运用CiteSpace软件对2010至2021年间中国知网收录的医学免疫学实验教学研究文献的发文量、作者合作网络、关键词共现网络、关键词聚类图谱、关键词时间线图谱以及关键词突现图谱6个方面进行可视化分析。结果显示,该领域近10年发文量较为平稳;已初步形成内部合作关系紧密的代表性研究团队;关键词共现图谱中具有较高中介中心性的关键词包括实验教学、免疫学、教学改革、实验课及医学生。同时,该领域研究内容已较为成熟,涵盖医学免疫学实验教学改革的整体研究,具体包括教学方法的实践探究、教学实践中特定学生及教师群体的研究3个方面。值得注意的是,“以学生为中心”的教育理念在实验教学方法的改革创新研究中得到各类医学高校专业教师的重视,注重培养学生科研思维、创新精神、自主学习能力以及综合素质的教学模式正日趋成型。本研究将有助于广大教师把握该领域的现状、热点及发展趋势,为提升课堂教学质量与开展后续教学改革提供理论支持和参考。

关键词：医学免疫学实验教学 CiteSpace 知识图谱分析

Transcutaneous electrical acupoint stimulation benefits postoperative pain relief of oocyte retrieval:A randomized controlled trial

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Journal of Integrative Medicine 2024年第1期22卷 32-38页

作者： Li-ying Liu Yang Su Rong-rong Wang yuan-yuan lai Lei Huang Yi-ting Li Xin-yue Tao Meng-hua Su Xiao-yan Zheng Shi-chen Huang Yong-na Wu Si-yi yu Fan-rong Liang Jie Yang Acupuncture and Tuina School Chengdu University of Traditional Chinese MedicineChengdu 610000Sichuan ProvinceChina Traditional Chinese Medicine Department Sichuan Jinxin Xi’nan Women's and Children's HospitalChengdu 610000Sichuan ProvinceChina

Background Transvaginal oocyte retrieval is frequently followed by adverse events related to anesthesia and the *** research showed that transcutaneous electrical acupoint stimulation(TEAS)can relieve intraoperative pain and postoperative *** This study examined whether TEAS can alleviate pain and relieve adverse symptoms after oocyte ***,setting,participants and interventions Altogether 128 patients were randomly divided into the TEAS group and the mock TEAS *** two groups received a 30-minute-long TEAS or mock TEAS treatment that began 30 min after oocyte *** outcome measures The primary outcome was the visual analog scale(VAS)pain *** outcomes were pressure pain threshold,McGill score,pain rating index(PRI),present pain intensity(PPI),VAS stress score,VAS anxiety score,and postoperative adverse *** The baseline characteristics of the two groups were comparable(P>0.05).The VAS pain scores of the TEAS group were lower than those of the mock TEAS group at 60 and 90 min after oocyte retrieval(P0.05).The TEAS group was superior to the mock TEAS group for relieving postoperative adverse symptoms(P<0.05).Conclusion TEAS treatment can relieve postoperative pain and postoperative adverse symptoms for patients undergoing oocyte retrieval.

关键词： Transcutaneous electrical acupoint stimulation Fertilization Embryo transfer Oocyte retrieval Pain Randomized controlled trial

Prediction of hepatic artery occlusion after liver transplantation by ultrasound characteristics and clinical risk factors

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World Journal of Radiology 2024年第6期16卷 196-202页

作者： yu-Ting lai Yi Chen Tai-Shi Fang Zhi-Yan Li Ning-Bo Zhao Department of Ultrasound National Clinical Research Centre for Infectious DiseasesThe Third People’s Hospital of ShenzhenThe Second Hospital Affiliated with the Southern University of Science and TechnologyShenzhen 518112Guangdong ProvinceChina Department of Liver Surgery National Clinical Research Centre for Infectious DiseasesThe Third People’s Hospital of ShenzhenThe Second Hospital Affiliated with the Southern University of Science and TechnologyShenzhen 518112Guangdong ProvinceChina

BACKGROUND Hepatic artery occlusion(HAO)after liver transplantation(LT)is a devastating complication,resulting in early graft loss and reduced overall ***-sound is an established assessment method for HAO in patients following LT,especially those with complex hepatic artery *** We retrospectively analyzed the ultrasound characteristics and the clinic risk factors associated with HAO in 400 adult LT patients who were enrolled and treated at the Third People's Hospital of Shenzhen between November 2016 and July *** patients diagnosed with acute HAO(A-HAO)by surgery and fifteen diagnosed with chronic HAO(C-HAO)were included.A control group of 33 patients without HAO complications during the same period were randomly selected using a random number *** patients underwent an ultrasono-graphy *** including resistance index(RI),peak systolic velocity(PSV),and portal vein velocity(PVV)were compared across the ***,basic clinical data were collected for all patients,including gender,age,primary diagnosis,D-dimer concentration,total operation time,cold ischemia time,hot ischemia time,intraoperative blood loss and transfusion,intraoperative urine volume,infusion,model for end-stage liver disease(MELD)score,and whether complex hepatic artery reconstructions were ***,risk factors influencing HAO formation after LT were *** Compared to the non-HAO group,PVV and RI were higher in the A-HAO group,while PSV was ***,both PSV and RI were lower in the C-HAO group compared to the non-HAO *** proportion of patients undergoing complex hepatic artery reconstructions and the gamma-glutamyltransferase(GGT)level before occlusion were significantly higher in the A-HAO group compared to the non-HAO ***,there were no distinct differences between the two groups in D-dimer,MELD score,pre-occlusion alanine transaminase and aspartate transaminase levels,or intrao

关键词： Hepatic artery occlusion Ultrasonography Diagnostic performance Risk factors Liver transplantation

Design of a high sensitivity and wide range angular rate sensor based on exceptional surface

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Chinese Physics B 2024年第8期33卷 277-286页

作者：丁鑫圣刘文耀王师贤陶煜周彦汝白禹刘来邢恩博唐军刘俊 State Key Laboratory of Dynamic Measurement Technology North University of ChinaTaiyuan 030051China Shanxi Province Key Laboratory of Quantum Sensing and Precision Measurement North University of ChinaTaiyuan 030051China

It is found that when the parity–time symmetry phenomenon is introduced into the resonant optical gyro system and it works near the exceptional point,the sensitivity can in theory be significantly amplified at low angular ***,in fact,the exceptional point is easily disturbed by external environmental variables,which means that it depends on harsh experimental environment and strong control ability,so it is difficult to move towards practical ***,we propose a new angular rate sensor structure based on exceptional surface,which has the advantages of high sensitivity and high *** system consists of two fiber-optic ring resonators and two optical loop mirrors,and one of the resonators contains a variable ratio coupler and a variable optical *** theoretically analyze the system response,and the effects of phase and coupling ratio on the system ***,compared with the conventional resonant gyro,the sensitivity of this exceptional surface angular rate sensor can be improved by about 300 times at low *** addition,by changing the loss coefficient in the ring resonator,we can achieve a wide range of 600 rad/*** scheme provides a new approach for the development of ultra-high sensitivity and wide range angular rate sensors in the future.

关键词： exceptional surface exceptional points ring resonator angular rate sensing rotational direction recognition wide operating range

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基于树结构Parzen估计器优化集成学习的短期负荷预测方法

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上海交通大学学报 2024年第6期58卷 819-825页

作者：罗敏杨劲锋俞蕙赖雨辰郭杨运周尚礼向睿童星陈潇南方电网数字电网研究院有限公司广州510000 中国南方电网有限责任公司广州510000 深圳市橙智科技有限公司广东深圳518000

短期负荷预测主要用于电力系统实时调度、日前发电计划的制定,对电力系统经济调度、系统的安全运行具有重要意义.国内外在采用智能模型进行短期负荷预测方面开展了大量研究,然而智能预测方法的预测效果较易受到现存方法结构及参数的影响... 详细信息

短期负荷预测主要用于电力系统实时调度、日前发电计划的制定,对电力系统经济调度、系统的安全运行具有重要意义.国内外在采用智能模型进行短期负荷预测方面开展了大量研究,然而智能预测方法的预测效果较易受到现存方法结构及参数的影响,以及预测对象自身个性差异使得参数难以复用,如何精准快速地获取方法结构与参数成为短期负荷预测的关键难题.对此,提出基于树结构Parzen估计器优化集成学习的短期负荷预测方法,可对方法结构与参数进行快速寻优.将该方法应用于中国南方某省短期负荷预测,以实际算例验证了其对预测精度的有效提升.

关键词：短期负荷预测树结构Parzen估计器集成学习超参优化

乙醇液滴冲击过冷水平壁面的铺展行为实验研究

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西安交通大学学报 2024年第1期58卷 119-125页

作者：张泽杨松刘秀芳赖天伟侯予西安交通大学能源与动力工程学院西安710049 西安交通大学深低温技术与装备教育部重点实验室西安710049

为探究表面张力对液滴冲击过冷水平壁面铺展动力学行为的影响,搭建了可视化实验系统,探究了乙醇液滴冲击过冷水平壁面的铺展动力学行为,分析了水平壁面过冷度对低表面张力液滴冲击铺展动力学行为的影响。实验中,采用亲水硅水平壁面及较... 详细信息

为探究表面张力对液滴冲击过冷水平壁面铺展动力学行为的影响,搭建了可视化实验系统,探究了乙醇液滴冲击过冷水平壁面的铺展动力学行为,分析了水平壁面过冷度对低表面张力液滴冲击铺展动力学行为的影响。实验中,采用亲水硅水平壁面及较小的冲击速度以观测乙醇液滴冲击过冷水平壁面的铺展动力学行为。此外,还比较了不同的最大铺展因子和最大铺展时间的典型模型对乙醇液滴冲击过冷水平壁面铺展动力学因子的适用性。结果表明:乙醇液滴冲击过冷亲水水平壁面的铺展动力学行为分为飞溅、铺展、稳定3个阶段;最大铺展时间随水平壁面过冷度的增大而减小;水平壁面过冷度对最大铺展因子的影响是非单调的,在水平壁面过冷度较低时,最大内部铺展因子减小起主要作用,在水平壁面过冷度较高时,由于瑞利-泰勒不稳定性的增强,无量纲手指状突起增大起主要作用,二者共同作用造成了非单调变化;现有模型对于最大铺展时间的预测效果较好,相对平均偏差为6.05%,而对最大铺展因子的预测效果较差。

关键词：液滴冲击过冷水平壁面表面张力铺展动力学行为

Erratum to: Photosensitivity sources of dissolved organic matter from wastewater treatment plants and their mediation effect on 17α-ethinylestradiol photodegradation

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Frontiers of Environmental Science & Engineering 2024年第9期18卷 118-118页

作者： Zhicheng Liao Bei Li Juhong Zhan Huan He Xiaoxia Yang Dongxu Zhou Guoxi yu Chaochao lai Bin Huang Xuejun Pan Faculty of Environmental Science and Engineering Kunming University of Science and Technology Kunming 650500 China Research Institute for Environmental Innovation (Suzhou) Tsinghua Suzhou 215163 China yunnan Provincial Key Laboratory of Carbon Sequestration and Pollution Control in Soils Kunming 650500 China

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关键词： wastewater dissolved treatment