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Boosting Photocatalytic Performance of Cu-Mn Co-doped CeO_(2) Nanoparticles for Tetracycline Degradation

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 42-48页

作者： XU Rongqi MI Jianxin WANG Shulin XU Man zhu Li BAI Lei TANG Dandan LEI yu Engineering Research Center of Environmental Materials and Membrane Technology of Hubei Province School of Materials Science and EngineeringWuhan Institute of TechnologyWuhan 430205China Shaanxi Coal Chemical Industry Technology Research Institute Co. Ltd.Xi’an 710100China

Cu-Mn co-doped CeO_(2) photocatalyst was successfully synthesized by the sol-gel method to assess its capability in degrading *** and TEM results showed that Cu and Mn were successfully co-doped into CeO_(2) without forming heterostructure,XPS and photoelectrochemical results revealed that Mn ions doping amplified the generation of photo-induced charge carriers,while Cu ions doping significantly facilitated the interfacial charge transfer ***,the optimized Cu3Mn2CeO_(2) nanoparticles exhibited the highest TC removal efficiency,achieved a rate of 78.18%and maintained a stable cycling performance.

关键词： photocatalyst co-doped charge separation water treatment

Copper-Catalyzed Double Thiolation to Access Sulfur-Bridged Imidazopyridines with Isothiocyanate

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Copper-Catalyzed Double Thiolation to Access Sulfur-Bridged ...

CNKSR2 interactome analysis indicates its association with the centrosome/microtubule system

中国化学会·第十六届全国有机合成化学学术研讨会

作者： yu-shen zhu Lu-Lu Tian Jing Li Xiao-Jie Zhang 朱新举 Xin-Qi Haoand Mao-Ping Song College of Chemistry and Molecular Engineering Zhengzhou University 郑州大学

The construction of C-S bonds is of fundamental research interest because of their wide applications in pharmaceuticals,organic syntheses,and materials science. Accordingly,a wide range of protocols have been developed to iltroduce a sulfur moiety onto target molecules. In our work,a copper(Ⅰ)-catalyzed sulfur-bridged dimerization of imidazopyridines has been developed using isothiocyanate as the sulfur *** method enables a switchable synthesis of bis(imidazo [1,2-a]pyridin-3-yl)sulfanes or bis(2-(imidazo [1,2-a]pyridin-2-yl)phenyl)sulfanes in the presence of4-dimethylaminopyridine(DMAP) or K CO when different imidazopyridines were *** optimized conditions,a variety of sulfur-bridged imidazopyridines were obtained in good ***,thiourea was proved to be the key intermediate under catalytic system A.

关键词： copper-catalyzed thiolation sulfur-bridged imidazopyridines isothiocyanate

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Neural Regeneration Research 2025年第8期20卷 2420-2432页

作者： Lin Yin Yalan Xu Jie Mu yu Leng Lei Ma yu Zheng Ruizhi Li Yin Wang Peifeng Li Hai zhu Dong Wang Jing Li Institute for Translational Medicine The Affiliated Hospital of Qingdao UniversityMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina School of Basic Medicine Qingdao UniversityQingdaoShandong ProvinceChina College of Life Sciences and School of PharmacyMedical CollegeQingdao UniversityQingdaoShandong ProvinceChina Department of Urology Qingdao Municipal Hospital Affiliated to Qingdao UniversityQingdaoShandong ProvinceChina

The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding *** of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully *** has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic ***,the function of CNKSR2 in the cytoplasm remains to be *** this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of *** a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the *** also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker *** colocalization analysis confirmed the centrosomal localization of *** we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal *** manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and ***,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum *** findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.

关键词： autism spectrum disorder centrosome CNKSR2 intellectual disability interactome mass spectrometry microtubule neurodevelopmental disease protein complexes protein-protein interactions

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POWER：知识丰富的智能网格工作流框架

通信学报 2006年第11期27卷 125-133页

作者：张少华向勇沈浴竹姜进磊史美林清华大学计算机科学与技术系北京100084

近年来,一些研究利用人工智能的规划技术来进行网格工作流的动态构建,但目前应用的方法尚缺乏显式知识支持,影响了系统的可扩展性。针对这个不足,定义了流程模式作为应用层知识表示工具；并基于模式提出了工作流动态生成的规划方法；进... 详细信息

近年来,一些研究利用人工智能的规划技术来进行网格工作流的动态构建,但目前应用的方法尚缺乏显式知识支持,影响了系统的可扩展性。针对这个不足,定义了流程模式作为应用层知识表示工具；并基于模式提出了工作流动态生成的规划方法；进而提出了一个支持多领域应用的,知识丰富,目标驱动网格工作流框架。

关键词：网格工作流流程模式面向模式的规划工作流生成框架

扩展BPEL4WS实现基于语义的服务流程动态细化

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通信学报 2006年第11期27卷 106-112页

作者：沈浴竹向勇张少华姜进磊史美林清华大学计算机科学与技术系北京100084

越来越多的企业采用面向服务的架构来构建其信息基础设施,并通过执行Web服务流程来实现其业务逻辑。然而,当前作为工业界标准的服务流程建模语言BPEL4WS只能支持非常有限的运行时动态性,难以适应复杂多变的业务需求。针对这一问题,提出... 详细信息

越来越多的企业采用面向服务的架构来构建其信息基础设施,并通过执行Web服务流程来实现其业务逻辑。然而,当前作为工业界标准的服务流程建模语言BPEL4WS只能支持非常有限的运行时动态性,难以适应复杂多变的业务需求。针对这一问题,提出了在BPEL4WS及其执行引擎之上,实现基于语义的服务流程动态细化的机制——在BPEL4WS中增加目标类型的活动以及流程的语义描述；扩展现有BPEL4WS执行引擎使之能够执行带有目标活动的流程,并能够根据目标描述与流程的数据内容,在运行时为目标活动匹配与绑定子流程。

关键词： Web服务流程细化扩展BPEL4WS语义Web 工作流

Role of the globus pallidus in motor and non-motor symptoms of Parkinson's disease

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Neural Regeneration Research 2025年第6期20卷 1628-1643页

作者： Yimiao Jiang Zengxin Qi Huixian zhu Kangli shen Ruiqi Liu Chenxin Fang Weiwei Lou Yifan Jiang Wangrui yuan Xin Cao Liang Chen Qianxing zhuang Department of Physiology School of MedicineNantong UniversityNantongJiangsu ProvinceChina Department of Neurosurgery Huashan HospitalShanghai Medical CollegeFudan UniversityShanghaiChina National Center for Neurological Disorders ShanghaiChina Shanghai Key Laboratory of Brain Function Restoration and Neural Regeneration ShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Institute of Brain ScienceFudan UniversityShanghaiChina

The globus pallidus plays a pivotal role in the basal ganglia circuit. Parkinson's disease is characterized by degeneration of dopamine-producing cells in the substantia nigra, which leads to dopamine deficiency in the brain that subsequently manifests as various motor and non-motor symptoms. This review aims to summarize the involvement of the globus pallidus in both motor and non-motor manifestations of Parkinson's disease. The firing activities of parvalbumin neurons in the medial globus pallidus, including both the firing rate and pattern, exhibit strong correlations with the bradykinesia and rigidity associated with Parkinson's disease. Increased beta oscillations, which are highly correlated with bradykinesia and rigidity, are regulated by the lateral globus pallidus. Furthermore,bradykinesia and rigidity are strongly linked to the loss of dopaminergic projections within the cortical-basal ganglia-thalamocortical loop. Resting tremors are attributed to the transmission of pathological signals from the basal ganglia through the motor cortex to the cerebellum-ventral intermediate nucleus circuit. The cortico–striato–pallidal loop is responsible for mediating pallidi-associated sleep disorders. Medication and deep brain stimulation are the primary therapeutic strategies addressing the globus pallidus in Parkinson's disease. Medication is the primary treatment for motor symptoms in the early stages of Parkinson's disease, while deep brain stimulation has been clinically proven to be effective in alleviating symptoms in patients with advanced Parkinson's disease,particularly for the movement disorders caused by levodopa. Deep brain stimulation targeting the globus pallidus internus can improve motor function in patients with tremordominant and non-tremor-dominant Parkinson's disease, while deep brain stimulation targeting the globus pallidus externus can alter the temporal pattern of neural activity throughout the basal ganglia–thalamus network. Therefore, the comp

关键词： anxiety basal ganglia bradykinesia deep brain stimulation depression globus pallidus externus globus pallidus internus lateral globus pallidus medial globus pallidus neural circuit Parkinson's disease

Fabrication of carbon-supported Al2O3 nanoparticles via spontaneous cross-linking to enhance selective hydrogenation of furfural

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Journal of Energy Chemistry 2025年第1期100卷 612-620页

作者： Weiwei yu Xinbao Zhang Hongyu Chen Yanan Wang Shaoguo Li Fucun Chen Zhenni Liu Xiujie Li Xiangxue zhu State Key Laboratory of Catalysis Dalian Institute of Chemical Physics Chinese Academy of Sciences

Selective hydrogenation of furfural to furfuryl alcohol is a great challenge in the hydrogenation field due to thermodynamic preference for hydrogenation of C=C over C=***,a novel Al2O3/C-u hybrid catalyst,composed of N-modified dendritic carbon networks supporting Al2O3nanoparticles,was successfully prepared via carbonizing the freeze-dried gel from spontaneous cross-linking of alginate,Al3+and *** obtained carbon-supported Al2O3hybrid catalyst has a high ratio （31%） of Al species in pentahedral-coordinated *** introduction of urea enhances the surface N content,the ratio of pyrrolic N,and specific surface area of catalyst,leading to improved adsorption capacity of C=O and the accessibility of active *** the furfural hydrogenation reaction with isopropyl alcohol as hydrogen donor,Al2O3/C-u catalyst achieved a 90%conversion of furfural with 98.0% selectivity to furfuryl alcohol,outperforming that of commercial γ-***,Al2O3/C-u demonstrates excellent catalytic stability in the recycling tests attributed to the synergistic effect of abundant weak Lewis acid sites and the anchoring effect of the carbon network on *** work provides an innovative and facile strategy for fabrication of carbon-supported Al2O3hybrid catalysts with rich AlVspecies,serving as a high selective hydrogenation catalyst through MPV reaction route.

关键词： Selective hydrogenation Furfural Furfuryl alcohol Cross-linking Carbon supported Al 2 O 3 MPV route

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工作流生成中的一种流程模式知识优化方法

计算机工程与应用 2008年第21期44卷 12-16页

作者：张少华向勇沈浴竹史美林清华大学计算机科学与技术系北京100084

基于模式的工作流生成利用规划技术和业务知识实现了工作流自动创建。流程模式知识的优劣直接影响到工作流生成结果的正确性。提出了一个针对流程模式的知识优化方法。在人工建模的基础上,针对流程模式知识构建场景分类器。利用流程规... 详细信息

基于模式的工作流生成利用规划技术和业务知识实现了工作流自动创建。流程模式知识的优劣直接影响到工作流生成结果的正确性。提出了一个针对流程模式的知识优化方法。在人工建模的基础上,针对流程模式知识构建场景分类器。利用流程规划运行的历史数据,通过机器学习对流程模式进行调整与优化,保证了工作流创建的正确性。

关键词：工作流生成流程模式场景分类器训练

High-temperature self-powered X-ray detection in a bilayered hybrid ferroelectric halide perovskite

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Science China Chemistry 2025年

作者： Yingying Zheng Panpan yu yunpeng Yao Shihai You Zeng-Kui zhu Junhua Luo School of Chemistry and Chemical Engineering Jiangxi Normal University Key Laboratory of Fluorine and Silicon for Energy Materials and Chemistry of Ministry of Education Jiangxi Normal University School of Environmental and Material Engineering Yantai University Fujian Science & Technology Innovation Laboratory for Optoelectronic Information of China

X-ray detectors which convert X-ray irradiation into electrical signals play an important role in diverse applications including medical diagnosis, security examination, nondestructive inspection, personal X-ray dosimeters and fundamental research[1–5]. Recently, metal halide perovskites（MHP） have been developed as a promising family for X-ray detection contributing to their intrinsic advantages, e.g.,simple synthesis, efficient X-ray absorption and excellent semiconducting properties[5–10].

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