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Soil Carbon Changes Following Afforestation with Olga Bay Larch （Larix olgensis Henry） in Northeastern China

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Journal of Integrative Plant Biology 2006年第5期48卷 503-512页

作者： Chun-Mel Wang Hua Ouyang Bin Shao yu-qiang tian Jing-Gang Zhao Huai-Yan Xu Institute of Geographical Sciences and Natural Resources Research the Chinese Acadmey of Sciences Beijing 100101 China Key Laboratory for Silviculture and Conservation of Ministry of Education Beijing Forestry University Beijing 100083 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China Dunhua Forest Bureau Jilin 133700 China

After converting cropland to forest, carbon Is sequestered in the aggradlng blomass of the new forests, but the question remains, to what extent will the former arable soil contribute as a sink for CO2？ Quantifying changes In soil carbon Is an Important consideration In the large-scale conversion of cropland to forest. Extensive field studies were undertaken to Identify a number of suitable sites for comparison of soil properties under pasture and forest. The present paper describes results from a study of the effects of first rotation larch on soil carbon In seven stands In an afforestation chronosequence compared with adjacent Korean pine, pasture, and cropland. An adjacent 250-year-old natural forest was Included to give Information on the possible long-term changes In soil carbon In northeast China In 2004. Soil carbon Initially decreased during the first 12 yr before a gradual recovery and accumulation of soil carbon occurred. The Initial （0-12 yr） decrease In soil carbon was an average 1.2% per year among case studies, whereas the Increase In soil carbon （12-33 yr） was 1.90% per year. Together with the carbon sequestration of forest floors, this led to total soil carbon stores of approximately 101.83 Mg/hm^2 over the 33-year chronosequence. Within the relatively short time span, carbon sequestration occurred mainly In tree blomees, whereas soil carbon stores were clearly higher In the 250-year-old plantation （184 Mg/hm^2）. The ongoing redistribution of mineral soil carbon In the young stands and the higher soil carbon contents In the 250-year-old afforested stand suggest that nutrient-rich afforestation soils may become greater sinks for carbon （C） In the long term.

关键词： afforestation carbon sequestration China forest litter mineral soil Olga Bay larch.

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前列腺原发性淋巴瘤一例报道并文献复习

中国全科医学 2017年第29期20卷 3692-3694页

作者：王宁于田强何佳段跃浙江省荣军医院泌尿外科浙江省嘉兴市311400

目的前列腺原发性淋巴瘤较为罕见,本文回顾性分析1例前列腺原发性淋巴瘤患者的临床资料,进一步探讨前列腺原发性淋巴瘤的临床诊断、治疗及预后。方法选取浙江省荣军医院泌尿外科2010-03-26收治的1例前列腺原发性淋巴瘤患者的临床资料。... 详细信息

目的前列腺原发性淋巴瘤较为罕见,本文回顾性分析1例前列腺原发性淋巴瘤患者的临床资料,进一步探讨前列腺原发性淋巴瘤的临床诊断、治疗及预后。方法选取浙江省荣军医院泌尿外科2010-03-26收治的1例前列腺原发性淋巴瘤患者的临床资料。分析其临床表现、实验室检查结果及诊治经过。结果本例患者血清前列腺特异性抗原(PSA)<4μg/L,盆腔CT提示前列腺明显增大,前列腺肿块,增强CT提示肿块无明显强化。超声提示前列腺明显增大,局部多发低回声病灶,病灶内血流信号丰富。组织病理学符合前列腺大B细胞型恶性淋巴瘤。行前列腺放射治疗后肿块明显减小。结论前列腺原发性淋巴瘤实验室检查、影像学检查具有特征性,对于临床诊断具有辅助意义。放射治疗是治疗前列腺原发性淋巴瘤的有效方法,可缓解尿路梗阻症状,必要时可联合化疗。

关键词：淋巴瘤前列腺肿瘤病例报告历史文献

A Novel Self-Supervised Learning Network for Binocular Disparity Estimation

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Computer Modeling in Engineering & Sciences 2025年第1期142卷 209-229页

作者： Jiawei tian yu Zhou Xiaobing Chen Salman A.AlQahtani Hongrong Chen Bo Yang Siyu Lu Wenfeng Zheng Department of Computer Science and Engineering Major in Bio Artificial IntelligenceHanyang UniversityAnsan-si15577Republic of Korea School of Electrical and Computer Engineering Louisiana State UniversityBaton RougeLA 70803USA Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadh11574Saudi Arabia School of Automation University of Electronic Science and Technology of ChinaChengdu610054China

Two-dimensional endoscopic images are susceptible to interferences such as specular reflections and monotonous texture illumination,hindering accurate three-dimensional lesion reconstruction by surgical *** study proposes a novel end-to-end disparity estimation model to address these *** approach combines a Pseudo-Siamese neural network architecture with pyramid dilated convolutions,integrating multi-scale image information to enhance robustness against lighting *** study introduces a Pseudo-Siamese structure-based disparity regression model that simplifies left-right image comparison,improving accuracy and *** model was evaluated using a dataset of stereo endoscopic videos captured by the Da Vinci surgical robot,comprising simulated silicone heart sequences and real heart video *** results demonstrate significant improvement in the network’s resistance to lighting interference without substantially increasing ***,the model exhibited faster convergence during training,contributing to overall performance *** study advances endoscopic image processing accuracy and has potential implications for surgical robot applications in complex environments.

关键词： Parallax estimation parallax regression model self-supervised learning Pseudo-Siamese neural network pyramid dilated convolution binocular disparity estimation

灰黄霉素对人前列腺癌PC-3细胞体内外作用的实验研究

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中华泌尿外科杂志 2012年第6期33卷 464-467页

作者：段跃徐庆康于田强洪翔武警浙江省总队医院泌尿外科嘉兴314000

目的探讨灰黄霉素在体内外对人前列腺癌PC-3细胞抗肿瘤作用的可能机制。方法不同浓度（0、5、10、15、20、25Izg／m1）的灰黄霉素作用于PC-3细胞48h，四甲基偶氮唑盐比色法测定细胞活率；荧光显微镜下观察细胞形态变化；膜联蛋白5一异... 详细信息

目的探讨灰黄霉素在体内外对人前列腺癌PC-3细胞抗肿瘤作用的可能机制。方法不同浓度（0、5、10、15、20、25Izg／m1）的灰黄霉素作用于PC-3细胞48h，四甲基偶氮唑盐比色法测定细胞活率；荧光显微镜下观察细胞形态变化；膜联蛋白5一异硫氰酸荧光素／碘化丙啶双标记染色法检测PC-3细胞的凋亡；比色法检测Caspase．3、8、9活性变化。采用灰黄霉素对PC-3细胞BALB／C荷瘤裸鼠瘤体内注射治疗，观察肿瘤生长变化，12d后免疫组化法检测Bcl-2、Bax、p53和Survivin的表达。结果灰黄霉素能抑制PC-3细胞增殖，半数抑制率浓度为（18．17±2．10）μg／ml；镜下可见典型的细胞凋亡形态学改变。15μg／ml灰黄霉素处理组PC-3细胞凋亡率（31．37±2．93）％，与对照组（2．89±0．67）％比较差异有统计学意义（P〈0．01）。15μg／ml灰黄霉素处理组PC-3细胞caspase-3、8、9的活性分别为0．562±0．050、0．337±0．053和0．293±0．038，对照组分别为0．113±0．014、0．120±0．017和0．109±0．018，组间比较差异有统计学意义（P〈0．01）。肿瘤接种后第23天，灰黄霉素组移植瘤体积为（961．17±78．12）mm^2，移植瘤质量为（742．50±78．63）mg，对照组为（1732．96±120．73）mm^2，（1387．33±71．47）mg，组间比较差异有统计学意义（P〈0．01）。灰黄霉素组Bcl-2、Bax、p53和Survivin蛋白表达阳性率分别为（16．10±3．45）％、（39．50±6．88）％、（48．20±8．04）％和（16．50±2．22）％，对照组分别为（41．30±3．95）％、（13．70±2．98）％、（17．60±3．21）％和（52．11±6．28）％，组间比较差异有统计学意义（P〈0．01）。结论灰黄霉素能抑制前列腺癌PC-3细胞的生长，诱导PC-3细胞凋亡并抑制PC-3细胞的动物体内致瘤能力。

关键词：灰黄霉素 PC-3细胞凋亡体内成瘤

Dip2a regulates stress susceptibility in the basolateral amygdala

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Neural Regeneration Research 2025年第6期20卷 1735-1748页

作者： Jing Li Zixuan He Weitai Chai Meng tian Huali yu Xiaoxiao He Xiaojuan Zhu Key Laboratory of Molecular Epigenetics Ministry of Education Institute of Genetics and CytologyNortheast Normal UniversityChangchunJilin ProvinceChina

Dysregulation of neurotransmitter metabolism in the central nervous system contributes to mood disorders such as depression, anxiety, and post–traumatic stress disorder. Monoamines and amino acids are important types of neurotransmitters. Our previous results have shown that disco-interacting protein 2 homolog A(Dip2a) knockout mice exhibit brain development disorders and abnormal amino acid metabolism in serum. This suggests that DIP2A is involved in the metabolism of amino acid–associated neurotransmitters. Therefore, we performed targeted neurotransmitter metabolomics analysis and found that Dip2a deficiency caused abnormal metabolism of tryptophan and thyroxine in the basolateral amygdala and medial prefrontal cortex. In addition, acute restraint stress induced a decrease in 5-hydroxytryptamine in the basolateral amygdala. Additionally, Dip2a was abundantly expressed in excitatory neurons of the basolateral amygdala, and deletion of Dip2a in these neurons resulted in hopelessness-like behavior in the tail suspension test. Altogether, these findings demonstrate that DIP2A in the basolateral amygdala may be involved in the regulation of stress susceptibility. This provides critical evidence implicating a role of DIP2A in affective disorders.

关键词： 5-hydroxytryptamine acute restraint stress basolateral amygdala CaMKII neurons DIP2A metabolomics neurotransmitters principal component analysis stress susceptibility tryptophan

Gamma-glutamyl transferase 5 overexpression in cerebrovascular endothelial cells improves brain pathology,cognition,and behavior in APP/PS1 mice

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Neural Regeneration Research 2025年第2期20卷 533-547页

作者： Yanli Zhang tian Li Jie Miao Zhina Zhang Mingxuan Yang Zhuoran Wang Bo Yang Jiawei Zhang Haiting Li qiang Su Junhong Guo Department of Neurology First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Neurology Sixth Hospital of Shanxi Medical University(General Hospital of Tisco)TaiyuanShanxi ProvinceChina Department of Physiology Key Laboratory of Cellular PhysiologyMinistry of EducationShanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Hernia and Abdominal Wall Surgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Laboratory Medicine of Fenyang College Shanxi Medical UniversityFenyangShanxi ProvinceChina

In patients with Alzheimer’s disease,gamma-glutamyl transferase 5(GGT5)expression has been observed to be downregulated in cerebrovascular endothelial ***,the functional role of GGT5 in the development of Alzheimer’s disease remains *** study aimed to explore the effect of GGT5 on cognitive function and brain pathology in an APP/PS1 mouse model of Alzheimer’s disease,as well as the underlying *** observed a significant reduction in GGT5 expression in two in vitro models of Alzheimer’s disease(Aβ_(1-42)-treated hCMEC/D3 and bEnd.3 cells),as well as in the APP/PS1 mouse ***,injection of APP/PS1 mice with an adeno-associated virus encoding GGT5 enhanced hippocampal synaptic plasticity and mitigated cognitive ***,increasing GGT5 expression in cerebrovascular endothelial cells reduced levels of both soluble and insoluble amyloid-βin the brains of APP/PS1 *** effect may be attributable to inhibition of the expression ofβ-site APP cleaving enzyme 1,which is mediated by nuclear factor-kappa *** findings demonstrate that GGT5 expression in cerebrovascular endothelial cells is inversely associated with Alzheimer’s disease pathogenesis,and that GGT5 upregulation mitigates cognitive deficits in APP/PS1 *** findings suggest that GGT5 expression in cerebrovascular endothelial cells is a potential therapeutic target and biomarker for Alzheimer’s disease.

关键词： Alzheimer’s disease amyloid-β APP/PS1 mice cerebrovascular endothelial cells cognitive deficits gamma-glutamyl transferase 5 neurovascular unit nuclear factor‐kappa B synaptic plasticity β-site APP cleaving enzyme 1

Mainchain conformation ordering self-assembly tailored room temperature phosphorescence emission

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Science China Chemistry 2025年第01期 329-336页

作者： yuzhu Li yumeng Gao Feng tian yu Wang yuan Yao Shaoliang Lin Xiang Ma Binbin Xu Shanghai Key Laboratory of Advanced Polymeric Materials Key Laboratory for Ultrafine Materials of Ministry of Education School of Materials Science and Engineering East China University of Science and Technology Shanghai Synchrotron Radiation Facility Shanghai Advanced Research Institute Chinese Academy of Sciences Key Laboratory for Advance Materials and Feringa Noble Prize Scientist Joint Research Centre Frontiers Science for Materiobiology and Dynamic Chemistry School of Chemistry and Molecular Engineering East China University of Science & Technology

Developing organic room-temperature phosphorescence （RTP） materials with a wide range of tunable-emission is significant in expanding the applications of RTP ***,we rationally designed amphiphilic alternating copolymers poly(1,2-bis（4-alkoxyphenyl）ethane-1,2-dione-alt-（ethylene glycol）x)(P（Bz-alt-EGx）) that combined the advantage of alternating benzil and EGxskeleton,and tunable mainchain *** a mainchain conformation ordering assembly （COA） process,P（Bz-alt-EGx） self-assembled into well-defined platelets,and such assemblies emitted blue RTP at ca.425 nm due to the ordered folded-chain conformation and confined *** contrast,traditional self-assembly （TA） of P（Bz-alt-EGx） obtained less ordered aggregates,such as asymmetric worms,vesicles,and rod-like *** resultant less ordered aggregates exhibited yellow-green RTP at ca.550 *** wide-tuning RTP emission in solution （between blue and yellow-green,over125 nm） is realized using the P（Bz-alt-EGx） alternating copolymers under the treatment of different self-assembly *** study uncovers a new strategy to tailor the RTP emission through different self-assembly pathways and holds great promise for the fabrication of advanced optical materials.

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Advances in the Development of Gradient Scaffolds Made of Nano-Micromaterials for Musculoskeletal Tissue Regeneration

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NANO-MICRO LETTERS 2025年第1期17卷 1-46页

作者： Fang, Lei Lin, Xiaoqi Xu, Ruian Liu, Lu Zhang, yu tian, Feng Li, Jiao Jiao Xue, Jiajia Beijing Univ Chem Technol Beijing Lab Biomed Mat Beijing 100029 Peoples R China Beijing Univ Chem Technol State Key Lab Organ Inorgan Composites Beijing 100029 Peoples R China Univ Technol Sydney Fac Engn & IT Sch Biomed Engn Sydney NSW 2007 Australia

This review highlights the gradient variations in the structural composition of musculoskeletal tissues and comprehensively examines recent progress in the fabrication and application of biomimetic gradient scaffolds for musculoskeletal *** challenges and prospects of gradient scaffolds for clinical application are discussed. The intricate hierarchical structure of musculoskeletal tissues, including bone and interface tissues, necessitates the use of complex scaffold designs and material structures to serve as tissue-engineered substitutes. This has led to growing interest in the development of gradient bone scaffolds with hierarchical structures mimicking the extracellular matrix of native tissues to achieve improved therapeutic outcomes. Building on the anatomical characteristics of bone and interfacial tissues, this review provides a summary of current strategies used to design and fabricate biomimetic gradient scaffolds for repairing musculoskeletal tissues, specifically focusing on methods used to construct compositional and structural gradients within the scaffolds. The latest applications of gradient scaffolds for the regeneration of bone, osteochondral, and tendon-to-bone interfaces are presented. Furthermore, the current progress of testing gradient scaffolds in physiologically relevant animal models of skeletal repair is discussed, as well as the challenges and prospects of moving these scaffolds into clinical application for treating musculoskeletal injuries.

关键词： Gradient scaffolds Musculoskeletal tissues Advanced manufacturing Biomaterials Tissue regeneration

Comparative analysis of empirical and deep learning models for ionospheric sporadic E layer prediction

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Earth and Planetary Physics 2025年第1期9卷 10-19页

作者： BingKun yu PengHao tian XiangHui Xue Christopher JScott HaiLun Ye JianFei Wu Wen Yi TingDi Chen XianKang Dou Institute of Deep Space Sciences Deep Space Exploration LaboratoryHefei 230088China CAS Key Laboratory of Geospace Environment School of Earth and Space SciencesUniversity of Science and Technology of ChinaHefei 230026China Hefei National Laboratory University of Science and Technology of ChinaHefei 230088China Department of Meteorology University of ReadingReading RG66BBUK

Sporadic E(Es)layers in the ionosphere are characterized by intense plasma irregularities in the E region at altitudes of 90-130 *** they can significantly influence radio communications and navigation systems,accurate forecasting of Es layers is crucial for ensuring the precision and dependability of navigation satellite *** this study,we present Es predictions made by an empirical model and by a deep learning model,and analyze their differences comprehensively by comparing the model predictions to satellite RO measurements and ground-based ionosonde *** deep learning model exhibited significantly better performance,as indicated by its high coefficient of correlation(r=0.87)with RO observations and predictions,than did the empirical model(r=0.53).This study highlights the importance of integrating artificial intelligence technology into ionosphere modelling generally,and into predicting Es layer occurrences and characteristics,in particular.

关键词： ionospheric sporadic E layer radio occultation ionosondes numerical model deep learning model artificial intelligence