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Integrating lipidomics and gut microbiota to study the anti-hyperlipidemia effect of Sargentodoxae Caulis extract

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Traditional Medicine Research 2025年第1期10卷 1-11页

作者： Xiao-Xiao Zhang Li Jia Xiu-Jun Zhan Charity Ngina qing-Rui Zhang Xiao-Ge Li qi-Bao jiang Shi Bai Miao-Miao jiang National Key Laboratory of Chinese Medicine Modernization Tianjin University of Traditional Chinese MedicineTianjin 301617China Haihe Laboratory of Modern Chinese Medicine Tianjin 301617China School of Medicine Taizhou UniversityTaizhou 318000China.

Background:Sargentodoxae Caulis(SC)is the vine stem of Sargentodoxa Cuneata(Oliv.)Rehd.&*** in ***,and it in traditional Chinese medicine has been known for promoting blood circulation and removing blood stasis as recorded in the ancient book“Illustrated Classics of Materia Medica”.It has been used effectively to treat blood stasis too in modern clinical ***,the anti-hyperlipidemia effect of SC is not fully *** paper aims at exploring the use of SC stems to improve the balance of blood lipids in the body,and its new role in treating ***:The effects of SC extract on hyperlipidemia were explored by combining lipidomics and gut ***,we explored the potential mechanism of SC in treating hyperlipidemia by pathway ***:The results showed that the stem extract of SC could restore the physiological and biochemical indices of hyperlipidemia in mice,as well as repair the morphological and structural damage to *** to the Model group,the SC extract significantly reduced the liver index,epididymal fat index,and Lee’s *** also significantly decreased serum levels of total cholesterol,triglycerides,low-density lipoprotein cholesterol,peroxisome proliferator-activated receptor gamma(PPAR-γ),D-lactate,and free fatty acids,while significantly increasing the relative content of peroxisome proliferator-activated receptor alpha(PPAR-α).These changes were statistically ***-targeted lipidomics,based on LC-MS,were utilized to investigate the lipid metabolism characteristics in serum,liver,and epididymal fat of the *** was observed that,compared to the blank group,the Model group exhibited significant changes primarily in glycerol lipids and *** treatment group also displayed alterations in these lipids.A total of 38,81,and 27 differential lipids were identified in serum,liver,and epididymal fat samples,*** these,14 common differenti

关键词： hyperlipidemia Sargentodoxae Caulis lipidomics intestinal flora

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基于积分调节器的改进型最大功率跟踪技术

电源技术 2018年第8期42卷 1190-1192页

作者：万凌云赵宇琪江渝张盈岳鑫桂国网重庆市电力公司电力科学研究院重庆401123 重庆大学输配电装备及系统安全与新技术国家重点实验室重庆400044

最大功率跟踪技术旨在通过调节电路使得光伏电池在任何外部条件下始终输出最大功率。搭建了光伏电池的行为数学模型,针对传统最大功率跟踪方法在跟踪速度和跟踪精度的不足之处,研究了一种基于积分调节器的改进型最大功率跟踪技术,并在Ma... 详细信息

最大功率跟踪技术旨在通过调节电路使得光伏电池在任何外部条件下始终输出最大功率。搭建了光伏电池的行为数学模型,针对传统最大功率跟踪方法在跟踪速度和跟踪精度的不足之处,研究了一种基于积分调节器的改进型最大功率跟踪技术,并在Matlab/Simulink环境下建立了仿真模型。仿真结果表明,该方法相比于传统方法具有更好的跟踪性能。

关键词：光伏并网发电系统光伏阵列最大功率跟踪电导增量法

Laser direct writing of flexible multifunctional airflow sensors on the Kevlar fabric

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Nano Research 2025年第1期18卷 443-454页

作者： Wei Wang Zi-qing Chen Yong-qi Li yu-Long Wang Mei-Chen Liu yun-Bo Ruan Yang Zhang Shu-Juan Liu qiang Zhao College of Electronic and Optical Engineering and College of Flexible Electronics(Future Technology) Nanjing University of Posts and TelecommunicationsNanjing 210023China State Key Laboratory of Organic Electronics and Information Displays and jiangsu Key Laboratory for Biosensors Institute of Advanced Materials(IAM)Nanjing University of Posts and TelecommunicationsNanjing 210023China Zhe jiang Topsun Logistic Control CO. LTD.Yuhuan 317600China Department of Rehabilitation Medicine School of Acupuncture-Moxibustion and Tuina and School of Health Preservation and RehabilitationNanjing University of Chinese MedicineNanjing 210023China

The growing interest in flexible devices has emerged as a global trend due to their advantages in flexibility,lightweight structure,and wearability,addressing the limitations of traditional *** wearable airflow sensors have been previously reported,the development of flexible fabric-based airflow sensors capable of functioning in environments with open flames—critical for fire rescue operations—has yet to be explored,largely due to the poor fire resistance of conventional *** this work,we first present a flexible,wearable,and multifunctional airflow sensor with excellent fire-resistant properties,fabricated through a simple direct laser writing *** sensor maintains airflow detection capabilities even in the presence of open ***,the fabrication of fabric-based sensors involves complex procedures such as carbon materials doping or vapor-phase deposition,leading to lengthy preparation cycles and high ***,fabric-based devices are inherently prone to *** address these challenges,we introduce twice-vertical laser-induced graphene(TVLIG)as a sensitive and reliable component for fire-resistant airflow *** resulting TVLIG/Kevlar fabric can be integrated into various garments,particularly protective suits,to form sensitive and fire-resistant airflow sensors capable of detecting airflow velocity and direction in both two-dimensional(2D)and three-dimensional(3D)spaces during fire ***,the TVLIG patterns can be expanded to multifunctional platforms,such as glucose detection for injured individuals,offering further applications in rescue *** functional expansion reduces the burden on rescue personnel and streamlines device *** its outstanding sensing capabilities,fire resistance,and expandability,the developed flexible airflow sensor shows great potential for various real-world rescue scenarios,promising advancements in wearable sensing technology for rescue enginee

关键词： flexible airflow sensor direct laser writing twice-vertical laser-induced graphene fire accident rescue Kevlar fabric

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

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Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-Long Zhou Wei-Jin jiang Ji yu Mao-Jun Yao yun-Tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

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应用pH传感针对穴位与非穴位pH值的测定

同济医科大学学报 1993年第5期22卷 373-375页

作者：喻凤兰江琦孔鄂生沈杰陈兴平任恕同济医科大学实验医学研究中心生物医学工程研究室武汉430030 武汉市针灸医院 430050

本文采用pH传感针,测定了30例健康人和72例慢性腰腿痛与肩臂痛者曲池穴和非穴位的pH值,结果:①63.3％的健康人pH值穴位低于非穴位(P<0.05);②患者的穴位与非穴位pH值差异与正常人基本一致,穴位低于非穴位占72％,穴位高于非穴位占28％;... 详细信息

本文采用pH传感针,测定了30例健康人和72例慢性腰腿痛与肩臂痛者曲池穴和非穴位的pH值,结果:①63.3％的健康人pH值穴位低于非穴位(P<0.05);②患者的穴位与非穴位pH值差异与正常人基本一致,穴位低于非穴位占72％,穴位高于非穴位占28％;③对同一穴位进行提插捻转治疗,运针后pH值明显上升(P<0.05);④患者与健康人曲池穴与非穴位pH值比较,显示出患者穴位与非穴位pH值均低于健康人(P<0.05)。

关键词： pH传感针 pH值穴位非穴位

An inverse problem to estimate an unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes' first problem for a heated generalized second grade fluid

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Acta Mechanica Sinica 2015年第2期31卷 153-161页

作者： Bo yu Xiaoyun jiang Haitao qi School of Mathematics Shandong University School of Mathematics and Statistics Shandong University

In this paper,we propose a numerical method to estimate the unknown order of a Riemann-Liouville fractional derivative for a fractional Stokes＇ first problem for a heated generalized second grade *** implicit numerical method is employed to solve the direct *** the inverse problem,we first obtain the fractional sensitivity equation by means of the digamma function,and then we propose an efficient numerical method,that is,the Levenberg-Marquardt algorithm based on a fractional derivative,to estimate the unknown order of a Riemann-Liouville fractional *** order to demonstrate the effectiveness of the proposed numerical method,two cases in which the measurement values contain random measurement error or not are *** computational results demonstrate that the proposed numerical method could efficiently obtain the optimal estimation of the unknown order of a RiemannLiouville fractional derivative for a fractional Stokes＇ first problem for a heated generalized second grade fluid.

关键词： Riemann-Liouville fractional derivative Generalized second grade fluid Inverse problem Implicit numerical method Fractional sensitivity equation

凋亡细胞及过氧化物酶体增殖物激活受体γ在子痫前期患者胎盘中的表达及临床意义

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大连医科大学学报 2016年第5期38卷 432-435页

作者：邹娜刘远远裘娟姜丹于水蒋奇大连市妇女儿童医疗中心病理科辽宁大连116037

目的研究中间型滋养细胞的凋亡及过氧化物酶体增殖物激活受体γ(PPARγ)在子痫前期患者胎盘中的表达及临床意义。方法收集2014-2016年间大连市妇女儿童医疗中心住院分娩的正常妊娠晚期(正常组)、轻度子痫前期(轻度子痫前期组)及重度子... 详细信息

目的研究中间型滋养细胞的凋亡及过氧化物酶体增殖物激活受体γ(PPARγ)在子痫前期患者胎盘中的表达及临床意义。方法收集2014-2016年间大连市妇女儿童医疗中心住院分娩的正常妊娠晚期(正常组)、轻度子痫前期(轻度子痫前期组)及重度子痫前期(重度子痫前期组)产妇胎盘组织,各30例。采用TUNEL法检测3组胎盘底板中间型滋养细胞的凋亡并计算凋亡指数(AI),采用免疫组化S-P法检测PPARγ的表达情况。结果正常妊娠晚期组、轻度子痫前期组及重度子痫前期组胎盘滋养细胞的AI分别为1.5860±0.2541、5.2609±2.8643及9.0000±6.2763,呈增高趋势,各组间差异有显著性意义(P<0.05)。PPARγ在正常妊娠晚期组、轻度子痫前期组及重度子痫前期组的表达阳性率分别为46.7%,93.3%,100%,呈增强趋势,各组间差异有显著性意义(P<0.05)。子痫前期胎盘组织中PPARγ与凋亡细胞的表达呈正相关(r=0.591,P<0.05)。结论 PPARγ可能通过诱导胎盘滋养细胞的凋亡参与子痫前期的发病。

关键词：中间型滋养细胞子痫前期细胞凋亡 PPARγ

Advances in green synthesis and applications of graphene

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Nano Research 2021年第11期14卷 3724-3743页

作者： qi yu Jianchao jiang Liyun jiang qingqing Yang Ning Yan Shaanxi Key Laboratory of Catalysis School of Materials Science and EngineeringShaanxi University of TechnologyHanzhong723001China Department of Chemical and Biomolecular Engineering National University of SingaporeSingapore117585Singapore

Green synthesis has grabbed appreciable attention to eliminate the negative effects associated with various chemical processes. Due to the unparalleled electrical, mechanical, thermal and excellent physical properties, graphene, as the thinnest two-dimensional material with high surface area, has the unfathomable potential in the domain of green chemistry in terms of both synthesis and application. In this regard, we present an overview of the research progresses on the greener synthesis of graphene, including micromechanical exfoliation, chemical reduction of graphene oxide (GO), chemical vapor synthesis and popping of GO. Meanwhile, various applications of graphene pertinent to sustainable developments, such as energy storage, catalysis, electrochemistry, fuel cell, supercapacitor and biomedicine have also been highlighted.

关键词： green chemistry graphene synthesis catalysis supercapacitor

Rapid, high-efficient and scalable exfoliation of high-quality boron nitride nanosheets and their application in lithium-sulfur batteries

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Nano Research 2021年第7期14卷 2424-2431页

作者： yu Chen qi Kang Pingkai jiang Xingyi Huang Frontiers Science Center for Transformative Molecules Department of Polymer Science and EngineeringShanghai Key Laboratory of Electrical Insulation and Thermal AgeingState Key Laboratory of Metal Matrix CompositesShanghai Jiao Tong UniversityShanghai 200240China

Boron nitride nanosheets(BNNSs)have gained significant attraction in energy and environment fields because of their two-dimensional(2D)nature,large band gap and high thermal/mechanical ***,the current low production efficiency of high-quality BNNSs is still a bottleneck limiting their ***,based on sonication-assisted liquid-phase exfoliation,we demonstrated a rapid,high-efficient and scalable production strategy of BNNSs and documented the effects of a spectrum of exfoliation factors(e.g.,ultrasonic condition,solvent and bulk material feeding)on the yield of BNNSs.A record of yield of 72.5%was achieved while the exfoliated BNNSs have few-layer and defect-free *** to the Lewis acid sites of the boron atoms,the BNNSs can interact with the polysulfide anions in liquid electrolyte and also can facilitate the uniform lithium deposition,which finally endow a lithium-sulfur(Li-S)battery with long *** work provides a facile and rapid strategy for large scale preparation of high-quality BNNSs,also contributes a long-life strategy for dendrite-free Li-S battery,opens new avenues of BNNSs in energy application.

关键词： boron nitride nanosheets cavitation sonication-assisted liquid-phase exfoliation(SALPE) modified separators lithium-sulfur batteries