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有序抖动图像逆半调的边缘敏感数字滤波算法

计算机工程与应用 2003年第31期39卷 100-102页

作者：余蓁曾平西安电子科技大学外部设备研究所西安710071

在图像有序抖动逆半调过程中选用传统的低通滤波会造成图像中边缘细节的模糊。为使图像处理结果具有较好的边缘特征,可将边缘区域和非边缘区域在逆半调的过程中分别进行处理。该文提出了将几种各具特点的逆半调方法分别应用于有序抖动... 详细信息

在图像有序抖动逆半调过程中选用传统的低通滤波会造成图像中边缘细节的模糊。为使图像处理结果具有较好的边缘特征,可将边缘区域和非边缘区域在逆半调的过程中分别进行处理。该文提出了将几种各具特点的逆半调方法分别应用于有序抖动半调图像的边缘敏感数字滤波算法中,以适用于多种对滤波效果和复杂度有不同要求的情况。

关键词：边缘敏感的数字滤波方法边缘检测选择滤波逻辑滤波

Acute and chronic excitotoxicity in ischemic stroke and late-onset Alzheimer's disease

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Neural Regeneration Research 2025年第7期20卷 1981-1988页

作者： Shan ping yu Emily Choi Michael QJiang Ling Wei Department of Anesthesiology Emory University School of MedicineAtlantaGAUSA Center for Visual and Neurocognitive Rehabilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke and Alzheimer's disease are common neurological disorders and often occur in the same *** comorbidity of the two neurological disorders represents a grave health threat to older *** review presents a brief background of the development of novel concepts and their clinical *** activity of glutamatergic N-methyl-D-aspartate receptors and N-methyl-D-aspartate receptor-mediated Ca^(2+)influx is critical for neuronal *** ischemic insult induces prompt and excessive glutamate release and drastic increases of intracellular Ca^(2+)mainly via N-methyl-D-aspartate receptors,particularly of those at the extrasynaptic *** Ca^(2+)-evoked neuronal cell death in the ischemic core is dominated by necrosis within a few hours and days known as acute ***,mild but sustained Ca^(2+)increases under neurodegenerative conditions such as in the distant penumbra of the ischemic brain and early stages of Alzheimer's disease are not immediately toxic,but gradually set off deteriorating Ca^(2+)-dependent signals and neuronal cell loss mostly because of activation of programmed cell death *** on the Ca^(2+)hypothesis of Alzheimer's disease and recent advances,this Ca^(2+)-activated“silent”degenerative excitotoxicity evolves from years to decades and is recognized as a unique slow and chronic *** N-methyl-D-aspartate receptor subunit GluN3A,primarily at the extrasynaptic site,serves as a gatekeeper for the N-methyl-D-aspartate receptor activity and is neuroprotective against both acute and chronic *** stroke and Alzheimer's disease,therefore,share an N-methyl-D-aspartate receptor-and Ca^(2+)-mediated mechanism,although with much different time *** is thus proposed that early interventions to control Ca^(2+)homeostasis at the preclinical stage are pivotal for individuals who are susceptible to sporadic late-onset Alzheimer's disease and Alzheimer's disease-related

关键词： Ca^(2+)hypothesis cognitive deficits hyperactivity late-onset Alzheimer's disease neurodegeneration N-methyl-D-aspartate receptors N-methyl-D-aspartate receptor subunits pathogenesis preventive treatment

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轮胎造型的花纹沟中心线算法

计算机工程与应用 2009年第36期45卷 241-243页

作者：郝泳涛俞平曾锦华同济大学CAD研究中心上海201804

提出了在CATIA二次开发轮胎花纹沟造型时关于花纹沟中心线的算法,它是在花纹沟造型时针对如何插入花纹沟截面以及生成深度沟造型所必须具备的相关技术,抽象出数学模型具有相当的通用性。提供了基本算法和改进的高精度算法,改进算法在基... 详细信息

提出了在CATIA二次开发轮胎花纹沟造型时关于花纹沟中心线的算法,它是在花纹沟造型时针对如何插入花纹沟截面以及生成深度沟造型所必须具备的相关技术,抽象出数学模型具有相当的通用性。提供了基本算法和改进的高精度算法,改进算法在基本算法之上通过对曲线的拟合和插值来生成更为准确的中心线数据。

关键词：计算机辅助立体界面应用(CATIA) 轮胎花纹沟拟合插值造型

Enhanced electrochemical CO_(2)reduction coupled with urea oxidation using bifunctional atomically dispersed CuNi catalysts

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Nano Research 2025年第1期18卷 208-216页

作者： Wenjie Wu Haoyang Zhou Ying Liu Yifei Pan Qingqing Chen yu Zhang Junjie Mao Wenjie Ma ping yu Beijing National Laboratory for Molecular Sciences Key Laboratory of Analytical Chemistry for Living BiosystemsInstitute of ChemistryChinese Academy of Sciences(CAS)Beijing 100190China College of Chemistry and Materials Science Anhui Normal UniversityWuhu 241002China University of Chinese Academy of Sciences Beijing 100049China

The electrochemical conversion of carbon dioxide(CO_(2))into chemical fuels represents a promising approach for addressing global carbon balance ***,this process is hindered by the kinetic limitations of anodic reactions,usually the oxygen evolution reaction,resulting in less efficient production of high value-added ***,we report an integrated electrocatalytic system that couples CO_(2)reduction reaction(CO_(2)RR)with urea oxidation reaction(UOR)using a bifunctional electrocatalyst with atomically dispersed dual-metal CuNi sites anchored on bamboo-like nitrogen-doped carbon nanotubes(CuNi-CNT),which were synthesized through a one-step pyrolysis *** bifunctional CuNi-CNT catalyst exhibits a near 100%CO Faraday efficiency for CO_(2)RR over a wide potential range and outstanding UOR performance with a negatively shifted potential of 210 mV at 10 mA·cm^(-2).In addition,we assemble a two-electrode electrolyzer using bifunctional CuNi-CNT-modified carbon fiber paper electrodes as both cathode and anode,capable of operating at a remarkably low cell voltage of 1.81 V at 10 mA·cm-2,significantly lower than conventional *** study provides a novel avenue to achieving an efficient carbon cycle with reduced electric power consumption.

关键词： electrochemical conversion bimetallic site catalyst bifunctional electrocatalyst carbon dioxide reduction urea oxidation

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基于物联网的种鸡生产管理系统的设计与实现

安徽农业科学 2017年第4期45卷 211-214页

作者：于群柳平增张艳山东农业大学信息科学与工程学院山东泰安271018

为实现种鸡的信息化和标准化管理,提高规模化养殖效率,设计并实现了种鸡生产管理系统。系统基于物联网3级架构,采用C/S开发模式,实现了种鸡鸡群引入、日常管理、孵化免疫等生产管理功能,并能进行环境精测和溯源跟踪,实现了各个生产阶段... 详细信息

为实现种鸡的信息化和标准化管理,提高规模化养殖效率,设计并实现了种鸡生产管理系统。系统基于物联网3级架构,采用C/S开发模式,实现了种鸡鸡群引入、日常管理、孵化免疫等生产管理功能,并能进行环境精测和溯源跟踪,实现了各个生产阶段的指标直观量化,可为种鸡养殖和品种改良提供数据参考。

关键词：物联网农业信息化种鸡生产溯源

Effect of microstructure on the low temperature toughness of high strength pipeline steels

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International Journal of Minerals,Metallurgy and Materials 2015年第3期22卷 254-261页

作者： Yan-ping zeng Peng-yu Zhu Ke Tong School of Materials Science and Engineering University of Science and Technology Beijing CNPC Tubular Goods Research Institute

Microstructure observations and drop-weight tear test were performed to study the microstructures and mechanical properties of two kinds of industrial X70 and two kinds of industrial X80 grade pipeline steels. The effective grain size and the fraction of high angle grain boundaries in the pipeline steels were investigated by electron backscatter diffraction analysis. It is found that the low temperature toughness of the pipeline steels depends not only on the effective grain size, but also on other microstructural factors such as martensite-austenite （MA） constituents and precipitates. The morphology and size of MA constituents significantly affect the mechanical properties of the pipeline steels. Nubby MA constituents with large size have significant negative effects on the toughness, while smaller granular MA constituents have less harmful effects. Similarly, larger Ti-rich nitrides with sharp corners have a strongly negative effect on the toughness, while fine, spherical Nb-rich carbides have a less deleterious effect. The low temperature toughness of the steels is independent of the fraction of high angle grain boundaries.

关键词： high strength pipe steels microstrucmre low temperature toughness influencing factors

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史氏鲟消化系统形态学与组织学观察

水产学报 2003年第1期27卷 1-6页

作者：曲秋芝华育平曾朝辉齐艳萍王永林王兵中国水产科学研究院黑龙江水产研究所东北林业大学野生动物资源学院东北林业大学野生动物资源学院黑龙江哈尔滨　150070 黑龙江哈尔滨　150040

通过对史氏鲟的活体解剖和对消化系统各组织的观察,结果表明史氏鲟具有胃、幽门盲囊和瓣肠,胰脏形成独立的器官,在肝门部有部分弥散于肝脏组织中。与同属的中华鲟比较,口腔粘膜褶数量和形态不同;食道分段数量不同(史氏鲟分3段、中华鲟分... 详细信息

通过对史氏鲟的活体解剖和对消化系统各组织的观察,结果表明史氏鲟具有胃、幽门盲囊和瓣肠,胰脏形成独立的器官,在肝门部有部分弥散于肝脏组织中。与同属的中华鲟比较,口腔粘膜褶数量和形态不同;食道分段数量不同(史氏鲟分3段、中华鲟分2段);史氏鲟瓣肠有7个螺旋瓣,比中华鲟少;中华鲟的幽门盲囊有17个小盲囊,而史氏鲟只有10～12个小盲囊。

关键词：形态学组织学消化系统史氏鲟

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World Journal of Clinical Cases 2025年第6期13卷 24-29页

作者： Wen-Jin yuan Yi-Juan Zheng Bing-Rong Zhang Yi-Jie Lin You Li Yan-Yan Qiu Xue-ping yu Department of Infection Disease Clinical Medical Research Center for Bacterial and Fungal Infectious Diseases of Fujian provinceFujian Medical University Affiliated First Quanzhou HospitalQuanzhou 362000Fujian ProvinceChina

BACKGROUND Hydroxyurea,an antimetabolite,is frequently prescribed for various hemato-logical disorders,and its common side effects include gastrointestinal problems,cutaneous or mucosal lesions and pyrexia/*** SUMMARY This study reports the case of a 67-year-old woman who developed recurrent abdominal pain after 10 years of continuous hydroxyurea therapy for primary *** revealed an ileocecal *** discontinuing hydroxyurea therapy for 6 months,follow-up colonoscopy showed a significant reduction in the *** We consider cecal ulcers as a rare complication of hydroxyurea therapy which typically resolves upon stopping the drug.

关键词： Hydroxyurea Ulcer Abdominal pain Thrombocythemia Colonoscopy Case report

Deciphering the molecular mechanisms of Simiaowan in the treatment of hyperuricemia: in vivo and in silico approaches

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Traditional Medicine Research 2025年第2期10卷 37-54页

作者： Yong-Chang zeng Jun-Hong Wu Dan-Dan Xu Kang He Chang-Qing Liu Li-Fei Song Zheng-Zhi Wu Qian-Qian Jiang Shao-yu Liang Department of Neurology The First Affiliated Hospital of Shenzhen UniversityShenzhen 518020China Pharmaceutical Department The Affiliated TCM Hospital of Guangzhou Medical UniversityGuangzhou 510000China School of Pharmacy Guizhou University of Traditional Chinese MedicineGuiyang 550025China Guangzhou Zeli Medical Technology Co. Ltd.Guangzhou 510700China

Background:Simiaowan(SMW),a well-known traditional Chinese medicine,has been employed to treat hyperuricemia(HUA)and gout for ***,the bioactive components and underlying mechanisms have not been *** objective of this study was to identify the active components and potential mechanisms of SMW by integrating pharmacological experimentation,serum pharmacochemistry,network pharmacology and molecular ***:HUA rats modelling by high-fat/high-sugar diet and potassium oxonate/adenine oral administration were used to evaluate the pharmacodynamic effects of ***-Q-Exactive-MS/MS was employed to detect the bioactive components present in SMW-containing *** pharmacology and molecular docking were utilized to elucidate the potential targets and underlying ***:SMW effectively ameliorated HUA rats via the inhibition of uric acid(UA)production,promotion of UA excretion,improvement of lipid and glucose metabolic abnormalities,antioxidant,anti-inflammatory and anti-insulin resistance effects.A total of 73 compounds detected in SMW-containing serum were identified as potential active components,with alkaloids,flavonoids,organic acids,and terpenoids emerging as the primary active *** 203 corresponding targets were obtained as SMW anti-HUA/gout targets,which mainly participated in apoptosis,insulin resistance,TNF,PI3K-Akt,HIF-1,NF-κB,MAPK,IL-17 and TLR signaling *** docking indicated that active compounds(***,phellodendrine,quercetin,formononetin,ferulic acid)had superior binding abilities to the key targets(*** carrier family 22 member 12(URAT1),solute carrier family 22 member 6(OAT1),ATP-binding cassette sub-family G member 2(ABCG2),solute carrier family 2,facilitated glucose transporter member 9(GLUT9),xanthine dehydrogenase/oxidase(XDH),transcription factor p65(RELA),toll-like receptor 4(TLR4),prostaglandin G/H synthase 2(PTGS2),caspase-3(CASP3),insulin(INS)).Conclusion:S

关键词： hyperuricemia network pharmacology serum pharmacochemistry Simiaowan UPLC-Q-Exactive-MS/MS