检索结果-南通市图书馆

Near-infrared 3D imaging with upconversion detection

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Photonics Research 2022年第12期10卷 2760-2767页

作者： HE ZHANG SANTOSH KUMAR YONG MENG SUA SHENyu ZHU yu-ping huang Department of Physics Stevens Institute of TechnologyHobokenNew Jersey 07030USA Center for Quantum Science and Engineering Stevens Institute of TechnologyHobokenNew Jersey 07030USA

We demonstrate a photon-sensitive,three-dimensional(3D)camera by active near-infrared illumination and fast time-of-flight *** uses picosecond pump pulses to selectively upconvert the backscattered photons according to their spatiotemporal modes via sum-frequency generation in a χ^(2) nonlinear crystal,which are then detected by an electron-multiplying CCD with photon sensitive *** such,it achieves sub-millimeter depth resolution,exceptional noise suppression,and high detection *** results show that it can accurately reconstruct the surface profiles of occluded targets placed behind highly scattering and lossy obscurants of14 optical depth(round trip),using only milliwatt illumination *** technique may find applications in biomedical imaging,environmental monitoring,and wide-field light detection and ranging.

关键词： illumination exceptional multiply

Corneal endothelial cell density and morphology and central corneal thickness in Guangxi Maonan and Han adolescent students of China

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2015年第3期8卷 608-611页

作者： Hao Liang Hui-Yi Zuo Jin-Mao Chen Jie Cai yu-Zhua Qin yu-ping huang Ying-Ying Chen Dong-Yong Tang Shao-Jian Tan Department of Ophthalmology the First Affiliated Hospital of Guangxi Medical University People's Hospital of Huanjiang Maonan Autonomous County

AIM: To investigate the corneal endothelial cell density and morphology and central corneal thickness in the Guangxi Maonan and Han adolescent students of ***: Noncontact specular microscope(Topcon SP3000 P, Tokyo, Japan) was performed in 133 adolescent students of Maonan nationality(M:F 54:79)and 105 adolescent students of Han nationality(M:F 50:55),5 to 20 y of age, who were randomly selected from 3schools in Huanjiang Maonan Autonomous County of Guangxi Zhuang Autonomous Region of *** studied included endothelial cell density,mean cell area, coefficient of variation in cell size,percentage hexagonality and central corneal thickness. RESULTS: Endothelial cell density, mean cell area,coefficient of variation in cell size, percentage hexagonality and central corneal thickness in the study population were(2969.50 ±253.93) cells/mm2,(339.23 ±29.44) μm2,(29.96 ±4.07) %,(64.58 ±9.41) % and(523.71 ±32.82) μm in Maonan and(2998.26 ±262.65) cells/mm2,(336.11±30.07) μm2,(29.89±5.03) %,(64.91±11.64) % and(524.39 ±33.15) μm in Han, respectively. No significant differences were observed in endothelial cell density,mean cell area, coefficient of variation in cell size,percentage hexagonality and central corneal thickness between Maonan and Han(P =0.615, 0.659, 0.528, 0.551,0.999). In Maonan and Han, we found age was negatively correlated with endothelial cell density and percentagehexagonality and positively correlated with mean cell area and coefficient of variation in cell size. Negative correlation was also found between central corneal thickness and age in Han, whereas no correlation was found in Maonan. CONCLUSION: There were no differences between Maonan and Han in corneal endothelial cell density and morphology and central corneal thickness. In these two nationalities, there were statistically significant decrease in endothelial cell density and percentage hexagonality with increasing age and statistically significant increase in cell area and coef

关键词： endothelial cell density morphology central corneal thickness Maonan

A New Definition and Calculation Model for Evolutionary Multi-Objective Optimization

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Wuhan University Journal of Natural Sciences 2003年第S1期8卷 189-194页

作者： Zhou Ai-min, Kang Li-shan, Chen yu-ping, huang yu-zhenState Key Laboratory of Software Engineering, Wuhan University, Wuhan 430072, Hubei, China State Key Laboratory of Software Engineering Wuhan University Wuhan Hubei China

We present a new definition (Evolving Solutions) for Multi-objective Optimization Problem (MOP) to answer the basic question (what's multi-objective optimal solution?) and advance an asynchronous evolutionary model (MINT Model) to solve MOPs. The new theory is based on our understanding of the natural evolution and the analysis of the difference between natural evolution and MOP, thus it is not only different from the Converting Optimization but also different from Pareto Optimization. Some tests prove that our new theory may conquer disadvantages of the upper two methods to some extent.

关键词： evolving equilibrium evolving solutions MINT model multi-objective optimization

Increase of β1-adrenergic receptor gene expression induced by nicotine in hippocampal slice of rat

在线全文

学校读者我要写书评

暂无评论

Acta Pharmacologica Sinica 2003年第12期24卷 107-112页

作者： WANG Yong, ZHU Xiao-Nan, YAN Jie yu Jian-ping, huang Xiao-Hui, CHEN Ru-Zhu Department of Pharmacology, Sun Yat-sen University of Medical Science, Guangzhou 510089, China Department of Pharmacology Sun Yat-sen University of Medical Science Guangzhou 510089 China

AIM: To investigate the effect of nicotine on β1-adrenergic receptor (β1-AR) in the hippocampal slice of rat. METHODS: Hippocampal slices (400 μm thick) were incubated in artificial cerebrospinal fluid (ACSF) previously saturated with 95％ O2and 5％ CO2at 28℃ for 120 min, and then incubated with nicotine 10 μmol/L for 30, 60, 90, and 120 min. mRNA of the β1-adrenergic receptor was examined with semiquantitative reverse transcription-polymerase chain reaction (RT-PCR), and the protein level was measured by Western blot and RIA. RESULTS: The mRNA gene expression and the protein level of β1-adrenergic receptor in hippocampal slices were increased after nicotine treatment. The peak of protein occurred later but higher than that of mRNA level. CONCLUSION: Both expression of β1-adrenergic receptor gene transcription and post-transcriptional protein level in rat hippocampus were altered by nicotine.

关键词： nicotine β-adrenergic receptors hippocampus reverse transcriptase polymerase chain reaction Western blotting radioligand assay

Acute and chronic excitotoxicity in ischemic stroke and late-onset Alzheimer's disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第7期20卷 1981-1988页

作者： Shan ping yu Emily Choi Michael QJiang Ling Wei Department of Anesthesiology Emory University School of MedicineAtlantaGAUSA Center for Visual and Neurocognitive Rehabilitation Atlanta Veterans Affairs Medical CenterDecaturGAUSA

Stroke and Alzheimer's disease are common neurological disorders and often occur in the same *** comorbidity of the two neurological disorders represents a grave health threat to older *** review presents a brief background of the development of novel concepts and their clinical *** activity of glutamatergic N-methyl-D-aspartate receptors and N-methyl-D-aspartate receptor-mediated Ca^(2+)influx is critical for neuronal *** ischemic insult induces prompt and excessive glutamate release and drastic increases of intracellular Ca^(2+)mainly via N-methyl-D-aspartate receptors,particularly of those at the extrasynaptic *** Ca^(2+)-evoked neuronal cell death in the ischemic core is dominated by necrosis within a few hours and days known as acute ***,mild but sustained Ca^(2+)increases under neurodegenerative conditions such as in the distant penumbra of the ischemic brain and early stages of Alzheimer's disease are not immediately toxic,but gradually set off deteriorating Ca^(2+)-dependent signals and neuronal cell loss mostly because of activation of programmed cell death *** on the Ca^(2+)hypothesis of Alzheimer's disease and recent advances,this Ca^(2+)-activated“silent”degenerative excitotoxicity evolves from years to decades and is recognized as a unique slow and chronic *** N-methyl-D-aspartate receptor subunit GluN3A,primarily at the extrasynaptic site,serves as a gatekeeper for the N-methyl-D-aspartate receptor activity and is neuroprotective against both acute and chronic *** stroke and Alzheimer's disease,therefore,share an N-methyl-D-aspartate receptor-and Ca^(2+)-mediated mechanism,although with much different time *** is thus proposed that early interventions to control Ca^(2+)homeostasis at the preclinical stage are pivotal for individuals who are susceptible to sporadic late-onset Alzheimer's disease and Alzheimer's disease-related

关键词： Ca^(2+)hypothesis cognitive deficits hyperactivity late-onset Alzheimer's disease neurodegeneration N-methyl-D-aspartate receptors N-methyl-D-aspartate receptor subunits pathogenesis preventive treatment

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang yu-Wen Alvin huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA Center for Translational Neuroscience Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase Cγ-Ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed deficiency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

High-temperature-tolerant flexible supercapacitors: Gel polymer electrolytes and electrode materials

在线全文

学校读者我要写书评

暂无评论

Journal of Energy Chemistry 2025年第1期100卷 426-457页

作者： Chong Peng Xinyi huang Mingwei Zhao Shuling Liao Quanhong Yang Nianjun Yang Siyu yu School of Chemistry & Chemical Engineering Southwest University Nanoyang Group Tianjin Key Laboratory of Advanced Carbon and Electrochemical Energy Storage School of Chemical Engineering and Technology and Collaborative Innovation Center of Chemical Science and Engineering (Tianjin) Tianjin University Department of Chemistry & IMO-IMOMEC Hasselt University

The development of flexible supercapacitors(FSCs) capable of operating at high temperatures is crucial for expanding the application areas and operating conditions of supercapacitors. Gel polymer electrolytes and electrode materials stand as two key components that significantly impact the efficacy of hightemperature-tolerant FSCs(HT-FSCs). They should not only exhibit high electrochemical performance and excellent flexibility, but also withstand intense thermal stress. Considerable efforts have been devoted to enhancing their thermal stability while maintaining high electrochemical and mechanical performance. In this review, the fundamentals of HT-FSCs are outlined. A comprehensive overview of state-of-the-art progress and achievements in HT-FSCs, with a focus on thermally stable gel polymer electrolytes and electrode materials is provided. Finally, challenges and future perspectives regarding HT-FSCs are discussed, alongside strategies for elevating operational temperatures and *** review offers both theoretical foundations and practical guidelines for designing and manufacturing HT-FSCs, further promoting their widespread adoption across diverse fields.

关键词： Flexible supercapacitors High-temperature tolerance Gel polymer electrolytes Electrode materials

随机激励下系统频率动态安全性量化评估及半解析分析

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

中国电机工程学报 2017年第7期37卷 1955-1962页

作者：李洪宇鞠平余一平黄晓明楼伯良黄弘扬河海大学能源与电气学院江苏省南京市210098 国网浙江省电力公司电力科学研究院浙江省杭州市310014

随着大规模可再生能源与电动汽车等的接入,电力系统中随机激励的类型逐渐增加、强度逐渐增强,系统频率的动态安全问题引起人们的关注。该文首先提出了域内概率(系统频率在安全允许范围内的概率)作为随机激励对系统频率动态安全性影响的... 详细信息

随着大规模可再生能源与电动汽车等的接入,电力系统中随机激励的类型逐渐增加、强度逐渐增强,系统频率的动态安全问题引起人们的关注。该文首先提出了域内概率(系统频率在安全允许范围内的概率)作为随机激励对系统频率动态安全性影响的量化评估指标。基于后向Kolmogorov方程,提出了可以快速求解域内概率的半解析法。最后通过仿真对比蒙特卡洛法与半解析法,验证了所提方法的有效性和快速性。该文从随机微分方程角度,揭示随机激励对系统频率动态安全性的影响机理,为随机激励下系统动态频率的分析提供新的方法。

关键词：随机激励系统频率动态安全性域内概率半解析法随机微分方程后向Kolmogorov方程

在线全文

学校读者我要写书评

暂无评论

船舶上建供排水系统管材的选用比较

船舶 2017年第4期28卷 64-68页

作者：於黄萍沪东中华造船(集团)有限公司上海200129

文章根据船舶上建供排水系统介质的特点,描述了系统及其使用的各种管材的特性,同时对各种管材在质量、价格、设计、施工等各方面进行对比,得出结论 :不锈钢管和紫铜管仍将继续使用,但塑料管优势明显,其应用会越来越广泛。

关键词：上层建筑供排水系统管材塑料管