检索结果-南通市图书馆

应变速率对HCP/FCC双相CoCrFeNiNb_(0.5)高熵合金力学性能的影响

在线全文

学校读者我要写书评

暂无评论

Transactions of Nonferrous Metals Society of China 2023年第4期33卷 1144-1155页

作者：马自豪侯兵秦冬阳李玉龙西北工业大学航空学院西安710072 西北工业大学民航学院西安710072

利用分离式霍普金斯压杆、扫描电子显微镜和透射电子显微镜研究应变速率对铸态CoCrFeNiNb_(0.5)高熵合金力学行为的影响。CoCrFeNiNb_(0.5)高熵合金由先共析密排六方(HCP)相和共析组织构成,合金的共析结构为片层状的HCP相和片层状的面... 详细信息

利用分离式霍普金斯压杆、扫描电子显微镜和透射电子显微镜研究应变速率对铸态CoCrFeNiNb_(0.5)高熵合金力学行为的影响。CoCrFeNiNb_(0.5)高熵合金由先共析密排六方(HCP)相和共析组织构成,合金的共析结构为片层状的HCP相和片层状的面心立方(FCC)相。当应变率从1×10^(-4)s^(-1)增加至6×10^(3)s^(-1)时,合金的屈服强度不会显著增加;然而,合金的破坏应变剧烈降低。片层状HCP相的准静态塑性变形机理为缠结状位错的增殖,而其动态塑性变形机理转变为剪切。片层状HCP相的剪切变形能够导致CoCrFeNiNb_(0.5)高熵合金在低压缩应变(ε=0.1)下形成微裂纹。由于片层状HCP相中微裂纹的数量随着动态压缩应变的提高而增加,微裂纹的扩展引发材料的雪崩式断裂。因此,铸造态CoCrFeNiNb_(0.5)高熵合金表现出显著的应变速率诱发脆性特性。

关键词：高熵合金共析结构高应变速率剪切韧-脆转变

Bowel preparation before colonoscopy: Consequences, mechanisms, and treatment of intestinal dysbiosis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 13-26页

作者： Ze-long Zheng Qing-Fan Zheng li-Qiang Wang Yi liu Department of Gastroenterology(Endoscopy Center) China-Japan Union Hospital of Jilin UniversityChangchun 130033Jilin ProvinceChina

The term“gut microbiota”primarily refers to the ecological community of various microorganisms in the gut,which constitutes the largest microbial community in the human *** adequate bowel preparation can improve the results of colonoscopy,it may interfere with the gut *** preparation for colonoscopy can lead to transient changes in the gut microbiota,potentially affecting an individual’s health,especially in vulnerable populations,such as patients with inflammatory bowel ***,measures such as oral pro-biotics may ameliorate these adverse *** focused on the bowel prepa-ration-induced changes in the gut microbiota and host health status,hypothesized the factors influencing these changes,and attempted to identify measures that may reduce dysbiosis,thereby providing more information for individualized bowel preparation for colonoscopy in the future.

关键词： Bowel preparation Colonoscopy Microbiota Inflammatory bowel disease Probiotics

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-long Zhou Wei-Jin Jiang Ji yu Mao-Jun Yao yun-Tong li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

煤岩“固-气”耦合相似材料力学特性与动态信号试验研究

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

西安科技大学学报 2017年第5期37卷 750-754页

作者：李莉翟雨龙李树刚西安科技大学安全科学与工程学院陕西西安710054 教育部西部矿井开采及灾害防治重点实验室陕西西安710054

为进一步研究"固-气"耦合相似材料力学特性,应用正交设计方法,设计5组力学参数相差均匀的材料配比,自行研制煤岩体单轴约束下振动及测试系统,研究了不同振动频率下相似材料力学特性变化规律,实验表明:加载频率为10~60 Hz试件的轴向应变... 详细信息

为进一步研究"固-气"耦合相似材料力学特性,应用正交设计方法,设计5组力学参数相差均匀的材料配比,自行研制煤岩体单轴约束下振动及测试系统,研究了不同振动频率下相似材料力学特性变化规律,实验表明:加载频率为10~60 Hz试件的轴向应变分别在0.74%,0.81%,0.94%,1.02%,1.03%及1.12%时达到峰值,此时压力传感器传输幅值时间变化阈值分别为32,47,52,62,65及95 s.当压力传感器传输幅值为0.2~0.6 N时,试件处于弹性阶段,不断积聚弹性应变能;当压力传感器传输幅值为0.8~1.5 N时,试件处于压力的强度极限,说明试件处于塑形阶段,开始释放弹性应变能。为"固-气"耦合物理相似模拟实验的开展进一步补充了实验基础。

关键词：相似材料机械振动力学特性振动幅值

Correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

在线全文

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng li Meifeng Cai Shengjun Miao yuan li yu Wang Key Laboratory of Ministry of Education for Efficient Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of Coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in China were adopted,a newly defined characteristic parameter C_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the C_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of C_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and C_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

在线全文

学校读者我要写书评

暂无评论

电站锅炉产品实现过程质量管控要点研究

锅炉制造 2022年第4期 24-25,28页

作者：于立龙哈尔滨锅炉厂有限责任公司黑龙江哈尔滨150046

本文通过对电站锅炉产品实现过程中的设计、工艺、采购、外包、制造、检验和安装服务全流程质量管控要点进行研究,探索适用于电站锅炉项目质量管理的科学方法,通过建立规范的管理流程保证产品制造可靠性,确保产品实物质量和服务质量全... 详细信息

本文通过对电站锅炉产品实现过程中的设计、工艺、采购、外包、制造、检验和安装服务全流程质量管控要点进行研究,探索适用于电站锅炉项目质量管理的科学方法,通过建立规范的管理流程保证产品制造可靠性,确保产品实物质量和服务质量全面满足法律法规和顾客要求。

关键词：电站锅炉全流程质量管控

Glutamatergic CYLD deletion leads to aberrant excitatory activity in the basolateral amygdala:association with enhanced cued fear expression

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3259-3272页

作者： Huidong li Faqin li Zhaoyi Chen Erwen Wu Xiaoxi Dai Danni li Haojie An Shiyi Zeng Chunyan Wang li Yang Cheng long School of life Sciences South China Normal UniversityGuangzhouGuangdong ProvinceChina School of life Sciences Guangzhou UniversityGuangzhouGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Major Obstetric Diseases The Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina South China Normal University-Panyu Central Hospital Joint Laboratory of Translational Medical Research Panyu Central HospitalGuangzhouGuangdong ProvinceChina

Neuronal activity,synaptic transmission,and molecular changes in the basolateral amygdala play critical roles in fear ***(CYLD)is a deubiquitinase that negatively regulates the nuclear factor kappa-B *** is well studied in non-neuronal cells,yet underinvestigated in the brain,where it is highly *** studies have shown involvement of CYLD in the remodeling of glutamatergic synapses,neuroinflammation,fear memory,and anxiety-and autism-like ***,the precise role of CYLD in glutamatergic neurons is largely ***,we first proposed involvement of CYLD in cued fear *** next constructed transgenic model mice with specific deletion of Cyld from glutamatergic *** results show that glutamatergic CYLD deficiency exaggerated the expression of cued fear in only male ***,loss of CYLD in glutamatergic neurons resulted in enhanced neuronal activation,impaired excitatory synaptic transmission,and altered levels of glutamate receptors accompanied by over-activation of microglia in the basolateral amygdala of male ***,our study suggests a critical role of glutamatergic CYLD in maintaining normal neuronal,synaptic,and microglial *** may contribute,at least in part,to cued fear expression.

关键词： basolateral amygdala cued fear expression cylindromatosis deubiquitinase glutamate receptor 1 glutamatergic neuron microglial activation N-methyl-D-aspartate receptor 1 neuronal activation synaptic transmission

li改性的Pt-Sn催化剂催化醋酸直接加氢制乙醇

在线全文

学校读者我要写书评

暂无评论

天然气化工—C1化学与化工 2017年第5期42卷 1-4页

作者：董玲玉李文龙李扬王科刘亚华夏伟袁小金西南化工研究设计院有限公司国家碳一化学工程技术研究中心工业排放气综合利用国家重点实验室四川成都610225

采用浸渍法制备氧化铝负载的Pt-Sn催化剂(Pt-Sn/liAlO、Pt-Sn/γ-Al_2O_3、Pt-Sn/α-Al_2O_3),采用X射线衍射(XRD)、物理吸附(BET)、NH_3-TPD等手段对催化剂进行表征,并在固定床反应器中评价了催化剂在醋酸直接加氢过程中的乙醇选择转... 详细信息

采用浸渍法制备氧化铝负载的Pt-Sn催化剂(Pt-Sn/liAlO、Pt-Sn/γ-Al_2O_3、Pt-Sn/α-Al_2O_3),采用X射线衍射(XRD)、物理吸附(BET)、NH_3-TPD等手段对催化剂进行表征,并在固定床反应器中评价了催化剂在醋酸直接加氢过程中的乙醇选择转化催化性能。结果表明,Pt-Sn/liAlO催化剂对醋酸直接加氢制乙醇具有良好的催化活性,li的添加有助于形成liAl_5O_8,li改性后的Pt-Sn催化剂具有适当的弱酸性位,有助于乙醇的选择转化。当n(li)/n(Al)为0.15时,Pt-Sn/liAlO催化剂醋酸直接加氢性能最佳,且该催化剂在反应500h后依然具有较好稳定性。

关键词： li改性 Pt-Sn催化剂醋酸加氢乙醇酸性位

Loss-of-function mutations of microRNA-142-3p promote ASH1L expression to induce immune evasion and hepatocellular carcinoma progression

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 126-145页

作者： Xing-Hui yu Yan Xie Jian yu Kun-Ning Zhang Zhou-Bo Guo Di Wang Zhao-Xian li Wei-Qi Zhang yu-Ying Tan li Zhang Wen-Tao Jiang School of Medicine Nankai UniversityTianjin 300192China Tianjin Key Laboratory of Molecular Diagnosis and Treatment of liver Cancer Tianjin First Center HospitalTianjin 300192China Department of liver Transplantation Tianjin First Center HospitalTianjin 300192China First Central Clinical School Tianjin Medical UniversityTianjin 300192China

BACKGROUND Hepatocellular carcinoma(HCC)has been a pervasive malignancy throughout the world with elevated *** therapeutic targets are beneficial to treat and predict the ***,the exact molecular mechanisms leading to the progression of HCC are still *** has shown that the microRNA-142-3p level decreases in HCC,whereas bioinformatics analysis of the cancer genome atlas database shows the ASH1L expression increased among liver tumor *** this paper,we will explore the effects and mechanisms of microRNA-142-3p and ASH1L affect the prognosis of HCC patients and HCC cell bioactivity,and the association between *** To investigate the effects and mechanisms of microRNA-142-3p and ASH1L on the HCC cell bioactivity and prognosis of HCC *** In this study,we grouped HCC patients according to their immunohistochemistry results of ASH1L with pathological tissues,and retrospectively analyzed the prognosis of HCC ***,explored the roles and mechanisms of microRNA-142-3p and ASH1L by cellular and animal experiments,which involved the following experimental methods:Immunohistochemical staining,western blot,quantitative real-time-polymerase chain reaction,flow cytometric analysis,tumor xenografts in nude mice,*** statistical methods involved in this study contained t-test,one-way analysis of variance,theχ^(2)test,the Kaplan-Meier approach and the log-rank *** In this study,we found that HCC patients with high expression of ASH1L possess a more recurrence rate as well as a decreased overall survival ***1L promotes the tumorigenicity of HCC and microRNA-142-3p exhibits reduced expression in HCC tissues and interacts with ASH1L through targeting the ASH1L 3′untranslated ***,microRNA-142-3p promotes apoptosis and inhibits proliferation,invasion,and migration of HCC cell lines in vitro via *** the exploration mechanism,we found ASH1L may promote an immunosuppressive mi

关键词： Hepatocellular carcinoma MicroRNA-142-3p ASH1L Immune evasion Tumor immune microenvironment Apoptosis