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Single-stage anterior debridement and reconstruction with tantalum mesh cage for complicated infectious spondylitis

World Journal of Orthopedics 2017年第9期8卷 710-718页

作者： Shih-Chieh Yang Hung-Shu Chen yu-hsien kao yuan-Kun Tu Department of Orthopedic Surgery E-Da Hospital I-Shou University

AIM To evaluate the clinical and radiographic results of patients with complicated infectious spondylitis treated with single-stage anterior debridement and reconstruction using tantalum mesh cage(TaMC) followed by immediate *** Single-stage radical debridement and subsequent reconstruction with TaMC instead of autograft or allograft were performed to treat 20 patients with spinal deformity or instability due to complicated infectious spondylitis. Clinical outcomes were assessed by careful physical examination and regular serological tests to determine the infection control. In addition, the visual analog score(VAS), neurologic status, length of vertebral body reconstruction, and the correction of sagittal Cobb angle on radiography were recorded and compared before and after surgery. The conditions of the patients were evaluated based on the modified Brodsky's *** The average VAS score significantly decreased after the surgery(from 7.4 ± 0.8 to 3.3 ± 0.8, P < 0.001). The average Cobb angle correction was 14.9 degrees. The neurologic status was significantly improved after the surgery(P = 0.003). One patient experienced refractory infection and underwent additional debridement. Eighteen patients achieved good outcome based on the modified Brodsky's criteria and significant improvement after the surgery(P < 0.001). No implant breakage orTaMC dislodgement was found during at least 24 mo of *** Single-stage anterior debridement and reconstruction with TaMC followed by immediate instrumentation could be an alternative method to manage the patients with spinal deformity or instability due to complicated infectious spondylitis.

关键词： Anterior reconstruction Complicated infectious spondylitis Instrumentation Spinal deformity Tantalum mesh cage

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Numerical Approach to Film Cooling Effectiveness Over a Plate Surface with Coolant Impingement

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Journal of Thermal Science 2004年第1期13卷 67-74页

作者： Chang-hsien Tai Jr-Ming Miao A-Fu kao Department of Vehicles Engineering National Pingtung University of Science and TechnologyPingtungTaiwanChinaDepartment of Mechanical EngineeringChung Cheng Institute of TechnologyNational Defense UniversityTaoyuanTaiwanChinaGraduate School of Defense Science StudiesChung Cheng Institute of TechnologyNational Defense UniversityTaoyuanTaiwanChina

The aim of the present study is conducting the numerical approach to a combination of internal jet impingement and external film cooling over a flat plate. A multi-block three-dimensional Navier-Stokes code, CFX 4.4, with k-e turbulence model is used to simulate this complicated thermal-flow structure induced by the interaction of coolant jet and hot cross mainstream. By assuming the adiabatic wall boundary condition on the tested film-cooled plate, both the local and the spanwise-averaged adiabatic film cooling effectiveness are evaluated for comparison of the cooling performance at blowing ratios of Br=0.5, 1.0, and 1.5. Film flow data were obtained from a row of five cylindrical film cooling holes, inclined in angle of 35?and 0?in direction of streamwise and spanwise, respectively. The film cooling hole spacing between adjacent holes is 15 mm for all the holes. Before the coolant flow being injected through individual cooling hole then encountered with the mainstream, an impingement chamber containing an impingement plate with 43 holes is located on the path of coolant flow. Present study also focused on the effect of impingement spacing, 10mm, 20mm, and 30mm. Compare the results, we find the impingement jet has a significant effect on the adiabatic film cooling effectiveness. As the coolant impingement spacing is fixed, results indicated that higher blowing ratio would enhance the local and the spanwise-averaged adiabatic film cooling effectiveness. Moreover, neither uniform nor parabolic distribution of pressure distribution are observed within the coolant hole-pipe.

关键词： film cooling impingement cooling CFD turbulence model.

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Coexistence of hepatoma with mantle cell lymphoma in a hepatitis B carrier

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World Journal of Gastroenterology 2015年第45期21卷 12981-12986页

作者： Mu-hsien Lee yu-Ching Lin Hao-Tsai Cheng Wen-yu Chuang Hsin-Chih Huang Hsiao-Wen kao Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Department of Intervention and Imaging Chang Gung Memorial Hospital and Chang Gung University College of Medicine Department of Pathology Chang Gung Memorial Hospital and Chang Gung University College of Medicine Department of Hematology-Oncology Chang Gung Memorial Hospital and Chang Gung University College of Medicine

The coexistence of hepatocellular carcinoma(HCC) and non-Hodgkin's lymphoma(NHL) in the liver is rare. Reports show that these patients have cirrhotic livers or hepatitis virus infections before they develop HCC and NHL. We present a patient with hepatitis B virus infection who was transferred to our hospital with a newly detected liver mass; abdominal computed tomography examination showed one hypodense mass of 7 cm in diameter and multiple mesenteric and mediastinal lymph nodes. A liver tumor biopsy showed a hepatoma, and the pathologic findings from an inguinal lymph node excision showed mantle cell lymphoma. An immunohistochemical stain confirmed that the atypical lymphoid cells within the HCC were positive for the CD20, CD5 and cyclin D1 antigens. Taking these findings into account, the hepatic tumor was determined to be a HCC infiltrated by mantle cell lymphoma.

关键词： Hepatocellular carcinoma Mantle cell lymphoma Hepa

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Numerical Simulation of Urea Based SNCR Process in a Trinal-Sprayed Precalciner

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Journal of Renewable Materials 2021年第2期9卷 269-294页

作者： yu Liu Hongtao kao College of Materials Science and Engineering Nanjing Tech UniversityNanjing211816China

In order to study the combustion characteristics,NOx emission and NH3 slip in a new trinal-sprayed precalciner,the simulations of combustion and aqueous urea solution based selective non-catalytic reduction(SNCR)process were conducted by computational fluid dynamics in this precalciner,the effects of different injection heights,different injection flow rates and stratified injection under different flow rates on SNCR process were *** results showed that the flow field was symmetrically distributed in the precalciner,and the flue gas from the rotary kiln formed the recirculation region on both sides of the cone body,which increased the residence time of the solid *** temperature was mainly between 1100 K and 1250 K in the middle and upper column of the precalciner,which met the demand of the pulverized coal combustion and raw material *** concentration of NO at the outlet of the precalciner was 559 ppm,moreover,different injection heights and different injection flow rates had a strong influence on NOX removal efficiency and NH3 *** aqueous urea solution should be injected at SNCR-1 to prolong the residence time of NH3,and injection flow rate had an optimal flow rate but not the higher the *** the injection flow rate under stratified injection was 0.019 kg/s,which could play a better optimization role on NO removal efficiency on the basic of the injection flow *** consideration of cost effective,a stratified injection with an injection flow rate of 0.019 kg/s and an injection height of 20 m,25 m and 30 m was suggested as a compromise of a satisfactory NOx reduction rates and reasonable NH3 *** this condition,numerical simulation result showed that NOx concentration at the outlet of precalciner was 297.27 mg/Nm3 and NH3 slip was 4.67 mg/Nm3,meeting emission standard.

关键词： Trinal-sprayed precalciner selective non-catalytic reduction aqueous urea solution NOx reduction

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All roads lead to Rome——Direct cervical carotid artery access in carotid artery intervention

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Journal of Geriatric Cardiology 2007年第2期4卷 115-116页

作者： hsien-Li kao National Taiwan University Hospital National Taiwan University Medical School 7 Chung-Shan South Road Taipei Taiwan China

　　Carotid artery stenting (CAS) is an alternative treatment for patients with severe carotid artery stenosis, especially those with prohibitively high surgical risks.……

关键词： Direct cervical carotid artery access in carotid artery intervention All roads lead to Rome

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Povacoat affecting solid-state polymorphic changes of indomethacin after co-evaporation from different types of solvents via conventional and microwave drying techniques

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Asian Journal of Pharmaceutical Sciences 2016年第3期11卷 376-384页

作者： Shan-Yang Lin Hong-Liang Lin Ying-Ting Chi Ru-Ying Hung yu-Ting Huang Chi-yu kao Wei-hsien Hsieh Department of Biotechnology and Pharmaceutical Technology Yuanpei University of Medical Technology

The effect of Povacoat on the solid state characteristics and polymorphic transformation of γ-form of indomethacin(γ-IMC) after solvent co-evaporation via two drying methods was investigated by thermoanalytical and FTIR spectroscopic studies. The types of solvents(water,ethanol, and water:ethanol(1:9 ～ 2:8, v/v)), weight ratios of Povacoat:IMC(4:1 ～ 4:10, w/w),and drying methods(air-drying and microwave-drying) were selected as variables in this study. A physical mixture of Povacoat and γ-IMC was also carried out by neat grinding *** results indicate that there was no interaction between Povacoat and γ-IMC or no polymorphic change of γ-IMC after the neat co-grinding process. Since Povacoat was only soluble in water or <30% ethanol aqueous solution but γ-IMC was only soluble in organic solvents,different solvents and drying methods might significantly influence the solid-state characteristics of IMC formed in the presence of Povacoat. It was found that the amorphous IMC was formed in the Povacoat/IMC evaporates after dissolving both Povacoat and γ-IMC in water:ethanol(mixed ratio=1:9 and 2:8, v/v) and co-evaporation via microwave-drying, whereas the α-IMC was formed in the Povacoat/IMC evaporates via the air-drying method. In addition, the predominate α-IMC formation was only found in all the Povacoat/IMC evaporates with different weight ratios prepared by previously dissolving in water:ethanol(1:9, v/v) and co-evaporation via air-drying, but the amorphous IMC formation after co-evaporation via microwave-drying was obtained except the 4:10(w/w) weight ratio. The thermal effect of microwave irradiation and the presence of Povacoat might be responsible for the amorphous IMC formation in the Povacoat/IMC evaporates.

关键词： Povacoat Indomethacin (IMC) Air-drying Microwave-drying α-IMC Amorphous IMC

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An evaluation of the inflammatory response of lipopolysaccharide-treated primary dental pulp cells with regard to calcium silicate-based cements

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International Journal of Oral Science 2014年第2期6卷 94-98页

作者： Wei-yun Lai Chia-Tze kao Chi-Jr Hung Tsui-hsien Huang Ming-You Shie School of Dentistry Chung Shan Medical University Department of Dentistry Chung Shan Medical University Hospital Institute of Oral Science Chung Shan Medical University

This study compared the biological changes of lipopolysaccharide （LPS）-treated dental pulp （DP） cells directly cultured on mineral trioxide aggregate （MTA） and calcium silicate （CS） cements. DP cells were treated with LPS for 24 h. Then, the LPS-treated DP cells were cultured on MTA or CS cements. Cell viability, cell death mechanism and interleukin （IL）-1β expressions were analysed. A one-way analysis of variance was used to evaluate the significance of the differences between the means. A significantly higher IL-1β expression （2.9-fold） was found for LPS-treated cells （P〈0.05） compared with DP cells without LPS treatment at 24 h. Absorbance values of LPS-treated cells cultured on CS cement were higher than a tissue culture plate. A significant difference （P〈0.05） in cell viability was observed between cells on CS and MTA cements 24 h after seeding. At 48 h, a high concentration of Si （5 mM） was released from MTA, which induced LPS-treated DP cell apoptosis. The present study demonstrates that CS cement is biocompatible with cultured LPS-treated DP cells. MTA stimulates inflammation in LPS-treated DP cells, which leads to greater IL-1β expression and apoptosis.

关键词： calcium silicate cement dental pulp cell mineral trioxide aggregate immune response interleukin-1β

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A Guaranteed Cost Approach to Dynamic Output Feedback Control for Neutral-Type Markovian Jumping Stochastic Systems

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Journal of Systems Science & Complexity 2021年第4期34卷 1487-1500页

作者： LI Yanbo kao Binghua XIE Jing kao Yonggui School of Information and Statistics Guangxi University of Finance and EconomicsNanning 530003China Department of Mathematics Harbin Institute of Technology(Weihai)Weihai 264209China School of Information and Control Engineering Qingdao University of TechnologyQingdao 266520China

This paper is devoted to investigating the dynamic output feedback(DOF)control problem of Markovian jump neutral-type stochastic systems with a guaranteed cost *** of the state and measurement equations contain time ***-dependent DOF controllers are first designed such that the closed-loop system is asymptotically stable in mean-square and an adequate performance level of this system is ***,sufficient conditions for the solvability of this problem are derived in the form of linear matrix inequalities(LMIs).A numerical example is presented to reveal the effectiveness of our findings.

关键词： Guaranteed cost control linear matrix inequality Markovian jump neutral stochastic systems output feedback control time delay

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Inter-Purchase Time Prediction Based on Deep Learning

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Computer Systems Science & Engineering 2022年第8期42卷 493-508页

作者： Ling-Jing kao Chih-Chou Chiu yu-Fan Lin Heong Kam Weng Department of Business Management National Taipei University of TechnologyTaipei106Taiwan Digital Transformation Institute Institute for Information IndustryTaipei106Taiwan

Inter-purchase time is a critical factor for predicting customer *** the prediction accuracy can exploit consumer’s preference and allow businesses to learn about product or pricing plan weak points,operation issues,as well as customer expectations to proactively reduce reasons for *** remarkable progress has been made,classic statistical models are difficult to capture behavioral characteristics in transaction data because transaction data are dependent and short-,medium-,and long-term data are likely to interfere with each other *** from literature,this study proposed a hybrid inter-purchase time prediction model for customers of on-line ***,the analysis of differences in the purchase behavior of customers has been particularly *** integrated self-organizing map and Recurrent Neural Network technique is proposed to not only address the problem of purchase behavior but also improve the prediction accuracy of inter-purchase *** permutation importance method was used to identify crucial variables in the prediction model and to interpret customer purchase *** performance of the proposed method is evaluated by comparing the prediction with the results of three competing approaches on the transaction data provided by a leading e-retailer in *** study provides a valuable reference for marketing professionals to better understand and develop strategies to attract customers to shorten their inter-purchase times.

关键词： Purchasing behavior e-commerce inter-purchase time self-organizing map recurrent neural network

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Asymptotic multistability and local S-asymptotic ω-periodicity for the nonautonomous fractional-order neural networks with impulses

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Science China(Information Sciences) 2021年第1期64卷 175-187页

作者： Yonggui kao Hui LI Department of Mathematics Harbin Institute of Technology at Weihai

This paper focuses on the investigation of asymptotic multistability and on local S-asymptoticω-periodicity for nonautonomous fractional-order neural networks(FONNs) with impulses. Several criteria on the existence, uniqueness, and invariant sets of nonautonomous FONNs with impulses are derived by constructing convergent sequences and comparison principles, respectively. In addition, using the Lyapunov direct method, some novel conditions of boundedness and local asymptotic stability of the FONNs discussed are obtained. Also, the sufficient conditions for local S-asymptotic ω-periodicities of the system are presented. Finally, a discussion using two examples verifies the validity of our findings, which imply that global asymptotic stability is a special case of asymptotic multistability.

关键词： fractional-order neural networks local S-asymptotic $\omega$-periodicity asymptotic multistability impulse nonautonomous

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