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Neural Regeneration Research 2025年第8期20卷 2169-2180页

作者： Mingyi yu Faith Teo en Ning chang Liu yu-chi Liu Tissue engineering and Stem cell Group Singapore Eye Research InstituteSingapore Yong Loo Lin School of Medicine National University of SingaporeSingapore Department of cornea and External Eye Disease Singapore National Eye CenterSingapore Ophthalmology and Visual Sc.ences Academic clinical Program Duke-NUS Medical SchoolSingapore

Diabetic corneal neuropathy and diabetic retinopathy are ocular complications occurring in the context of diabetes *** corneal neuropathy refers to the progressive damage of corneal *** retinopathy has traditionally been considered as damage to the retinal ***,growing evidence suggests that diabetic retinopathy is a complex neurovascular disorder resulting from dysfunction of the neurovascular unit,which includes both the retinal vascular structures and neural *** retinopathy is one of the leading causes of blindness and is frequently screened for as part of diabetic ocular ***,diabetic corneal neuropathy is commonly overlooked and underdiagnosed,leading to severe ocular surface *** studies have found that these two conditions tend to occur together,and they share similarities in their pathogenesis pathways,being triggered by a status of chronic *** review aims to discuss the interconnection between diabetic corneal neuropathy and diabetic retinopathy,whether diabetic corneal neuropathy precedes diabetic retinopathy,as well as the relation between the stage of diabetic retinopathy and the severity of corneal *** also endeavor to explore the relevance of a corneal screening in diabetic eyes and the possibility of using corneal nerve measurements to monitor the progression of diabetic retinopathy.

关键词： cornea corneal nerves diabetes diabetic corneal neuropathy diabetic retinopathy retina

MXene Hybridized Polymer with enhanced Electromagnetic.energy Harvest for Sensitized Microwave Actuation and Self‑Powered Motion Sensing

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Nano-Micro Letters 2025年第3期17卷 265-279页

作者： yu‑Ze Wang yu‑chang Wang Ting‑Ting Liu Quan‑Liang Zhao c.en‑Sha Li Mao‑Sheng cao School of Materials Sc.ence and engineering Beijing Institute of TechnologyBeijing 100081People’s Republic of China School of Materials Sc.ence and engineering Peking UniversityBeijing 100871People’s Republic of China School of Mechanical and Material engineering North China University of TechnologyBeijing 100144People’s Republic of China Key Laboratory of Functional Inorganic Material chemistry Ministry of Education of the People’s Republic of ChinaHeilongjiang UniversityHarbin 150080People’s Republic of China

Polymeric microwave actuators combining tissue-like softness with programmablemicrowave-responsive deformation hold great promise for mobile intelligentdevices and bionic soft robots. However, their application is challenged by restricted electromagnetic.ensitivity and intricate sensing coupling. In this study, a sensitized polymericmicrowave actuator is fabricated by hybridizing a liquid crystal polymer with Ti3c2Tx(MXene). compared to the initial counterpart, the hybrid polymer exhibits unique spacechargepolarization and interfacial polarization, resulting in significant improvements of230% in the dielectric loss factor and 830% in the apparent effic.ency of electromagneticenergy harvest. The sensitized microwave actuation demonstrates as the shortenedresponse time of nearly 10 s, which is merely 13% of that for the initial shape memory polymer. Moreover, the ultra-low content of MXene (upto 0.15 wt%) benefits for maintaining the actuation potential of the hybrid polymer. An innovative self-powered sensing prototype that combinesdriving and piezoelectric polymers is developed, which generates real-time electric potential feedback (open-circuit potential of ~ 3 mV) duringactuation. The polarization-dominant energy conversion mechanism observed in the MXene-polymer hybrid structure furnishes a new approachfor developing effic.ent electromagnetic dissipative structures and shows potential for advancing polymeric electromagnetic intelligent devices.

关键词： Microwave absorption Electromagnetic response energy harvest Self-sensing Soft actuator

Targeting TrkB–PSD-95 coupling to mitigate neurological disorders

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Neural Regeneration Research 2025年第3期20卷 715-724页

作者： Xin Yang yu-Wen Alvin Huang John Marshall Department of Molecular Biology Cell Biology and BiochemistryBrown UniversityProvidenceRIUSA Department of Neurology Warren Alpert Medical School of Brown UniversityProvidenceRIUSA center for Translational Neurosc.ence Robert J.and Nancy D.Carney Institute for Brain Science and Brown Institute for Translational ScienceBrown UniversityProvidenceRIUSA

Tropomyosin receptor kinase B(TrkB)signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and *** activity-dependent release of brain-derived neurotrophic factor at synapses binds to pre-or postsynaptic TrkB resulting in the strengthening of synapses,reflected by long-term ***,the association of postsynaptic density protein-95 with TrkB enhances phospholipase cγ-ca^(2+)/calmodulin-dependent protein kinaseⅡand phosphatidylinositol 3-kinase-mechanistic target of rapamycin signaling required for long-term *** this review,we discuss TrkB-postsynaptic density protein-95 coupling as a promising strategy to magnify brain-derived neurotrophic factor signaling towards the development of novel therapeutics for specific neurological disorders.A reduction of TrkB signaling has been observed in neurodegenerative disorders,such as Alzheimer's disease and Huntington's disease,and enhancement of postsynaptic density protein-95 association with TrkB signaling could mitigate the observed defic.ency of neuronal connectivity in schizophrenia and *** with brain-derived neurotrophic factor is problematic,due to poor pharmacokinetics,low brain penetration,and side effects resulting from activation of the p75 neurotrophin receptor or the truncated TrkB.T1 *** TrkB agonists and antibodies that activate TrkB are being intensively investigated,they cannot distinguish the multiple human TrkB splicing isoforms or cell type-specific *** TrkB–postsynaptic density protein-95 coupling provides an alternative approach to specifically boost TrkB signaling at localized synaptic sites versus global stimulation that risks many adverse side effects.

关键词： Angelman syndrome autism brain-derived neurotrophic factor depression neurodegenerative disorder neurodevelopmental disorder postsynaptic density protein-95 synaptic plasticity TrkB

correlation between the rock mass properties and maximum horizontal stress:A case study of overcoring stress measurements

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 39-48页

作者： Peng Li Meifeng cai Shengjun Miao yuan Li yu Wang Key Laboratory of Ministry of Education for Effic.ent Mining and Safety of Metal Mines University of Science and Technology BeijingBeijing 100083China State Key Laboratory of coal Resources and Safe Mining China University of Mining and TechnologyXuzhou 221116China

Understanding the mechanical properties of the lithologies is crucial to accurately determine the horizontal stress *** investigate the correlation between the rock mass properties and maximum horizontal stress,the three-dimensional(3D)stress tensors at 89 measuring points determined using an improved overcoring technique in nine mines in china were adopted,a newly defined characteristic parameter c_(ERP)was proposed as an indicator for evaluating the structural properties of rock masses,and a fuzzy relation matrix was established using the information distribution *** results indicate that both the vertical stress and horizontal stress exhibit a good linear growth relationship with *** is no remarkable correlation between the elastic modulus,Poisson's ratio and depth,and the distribution of data points is scattered and ***,there is no obvious relationship between the rock quality designation(RQD)and *** maximum horizontal stress σ_(H) is a function of rock properties,showing a certain linear relationship with the c_(ERP)at the same *** addition,the overall change trend of σ_(H) determined by the established fuzzy identification method is to increase with the increase of c_(ERP).The fuzzy identification method also demonstrates a relatively detailed local relationship betweenσ_H and c_(ERP),and the predicted curve rises in a fluctuating way,which is in accord well with the measured stress data.

关键词： overcoring stress measurements elastic modulus Poisson's ratio rock quality designation maximum horizontal stress fuzzy identification

Ideal Bi‑Based Hybrid Anode Material for Ultrafast charging of Sodium‑Ion Batteries at Extremely Low Temperatures

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Nano-Micro Letters 2025年第3期17卷 152-167页

作者： Jie Bai Jian Hui Jia yu Wang chun c.eng Yang Qing Jiang Key Laboratory of Automobile Materials(Jilin University) Ministry of EducationSchool of Materials Science and EngineeringJilin UniversityChangchun 130022People’s Republic of China

Sodium-ion batteries have emerged as competitive substitutes for low-temperature applications due to severe capacity loss and safety concerns of lithium-ion batteries at−20°c or ***,the key capability of ultrafast charging at ultralow temperature for SIBs is rarely ***,a hybrid of Bi nanoparticles embedded in carbon nanorods is demonstrated as an ideal material to address this issue,which is synthesized via a high temperature shock *** a hybrid shows an unprecedented rate performance(237.9 mAh g^(−1)at 2 A g^(−1))at−60℃,outperforming all reported SIB anode *** with a Na_(3)V_(2)(PO_(4))_(3)cathode,the energy density of the full cell can reach to 181.9 Wh kg^(−1)at−40°*** on this work,a novel strategy of high-rate activation is proposed to enhance performances of Bi-based materials in cryogenic conditions by creating new active sites for interfacial reaction under large current.

关键词： Bi nanoparticles High temperature shock High-rate activation Ultrafast charging Low-temperature sodium-ion batteries

Boosting bidirectional sulfur conversion enabled by introducing boron-doped atoms and phosphorus vacancies in Ni2P for lithium-sulfur batteries

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Journal of energy chemistry 2025年第1期100卷 760-769页

作者： Lin Peng yu Bai Hang Li Meixiu Qu Zhenhua Wang Kening Sun Advanced Research Institute of Multidisciplinary Sc.ence Beijing Institute of Technology Beijing Key Laboratory of chemical Power Source and Green catalysis School of Chemistry and Chemical Engineering Beijing Institute of Technology

Lithium-sulfur （Li-S） batteries have gained great attention due to the high theoretical energy density and low cost,yet their further commercialization has been obstructed by the notorious shuttle effect and sluggish redox ***,we supply a strategy to optimize the electron structure of Ni2P by concurrently introducing B-doped atoms and P vacancies in Ni2P （Vp-B-Ni2P）,thereby enhancing the bidirectional sulfur *** study indicates that the simultaneous introduction of B-doped atoms and P vacancies in Ni2P causes the redistribution of electron around Ni atoms,bringing about the upward shift of d-band center of Ni atoms and effective d-p orbital hybridization between Ni atoms and sulfur species,thus strengthening the chemical anchoring for lithium polysulfides （LiPSs） as well as expediting the bidirectional conversion kinetics of sulfur ***,theoretical calculations reveal that the incorporation of B-doped atoms and P vacancies in Ni2P selectively promotes Li2S dissolution and nucleation ***,the Li-S batteries with Vp-B-Ni2P-separators present outstanding rate ability of 777 m A h g-1at 5 c and high areal capacity of 8.03 mA h cm-2under E/S of 5μL mg-1and sulfur loading of 7.20 mg *** work elucidates that introducing heteroatom and vacancy in metal phosphide collaboratively regulates the electron structure to accelerate bidirectional sulfur conversion.

关键词： Lithium sulfur batteries

On-demand Direct Design of Polymeric Thermal Actuator by Machine Learning Algorithm

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chinese Journal of Polymer Sc.ence 2020年第8期38卷 908-914,I0009页

作者： Bo-en Liu Wei yu Advanced Rheology Institute Department of Polymer Science and EngineeringState Key Laboratory for Metal Matrix Composite MaterialsShanghai Key Laboratory of Electrical Insulation and Thermal AgeingShanghai Jiao Tong UniversityShanghai 200240China

The design optimization of thermal-driven actuators is a challenging task because the performance depends on multiple materials parameters,structural parameters,and working *** this work,we adopted large scale finite element simulation together with machine learning algorithm to fulfill the on-demand design of thermal *** element analysis was used to simulate the performance of thermal actuator with two-layer structure,which generated large amount of dataset by considering the variation of parameters including the moduli,thermal expansion coeffic.ent,sample thickness and length,and *** vector regression(SVR)was adopted to establish the relationship between multiple input parameters and the resulting contact ***,a simple interior point algorithm was used to achieve the on-demand design based on the SVR *** contact pressures of thermal actuator constructed from the optimized parameters deviated less than 15%of the target values.

关键词： Polymer composites Thermal actuator Finite element analysis Support vector regression

Firm-level Strategic competition and Peer Effects in corporate Investment among chinese Firms

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Journal of Systems Sc.ence and Systems engineering 2022年第6期31卷 753-774页

作者： Jianing Li yu-en Lin School of Business Administration Northeastern UniversityShenyangLiaoning110000China center for Quantitative Economics Jilin UniversityChangchunjilin130015China

This study investigates the influence of strategic competition on peer effects in corporate investment by using a sample of 28,522 observations of chinese listed companies from 2008 to *** study develops a linear-in means model and uses an instrumental variables approach,and uses the competitive strategy measure(cSM)and Lerner index as proxies of competitive strategies and competitive positions to capture the firm-level *** empirical results demonstrate that when firms compete as strategic substitutes and when firms are in higher competitive positions,the peer effects in corporate investment are significant and *** addition,in circumstances of high information asymmetry,firms competing as strategic substitutes and firms in high competitive positions rely more on information related to investment from peer ***,industry policies and barriers do not significantly influence peer effects in *** study offers new empirical evidence regarding peer effects in corporate investment in china.

关键词： corporate investment peer effects competitive strategy competitive position

Fluorinated poly(p-triphenylene isatin) anion exchange membranes based on hydrophilic hydroxyl side chain modulation for fuel cells

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Journal of energy chemistry 2025年第1期100卷 702-709页

作者： Yiman Gu Yanchao Zhang Zhanyu Li Yijia Lei Baozeng Sun Xiaoyu yu Zhe Wang college of chemistry and Life Sc.ence Changchun University of Technology college of chemical engineering Changchun University of Technology School of Materials Sc.ence and engineering Changchun University of Technology Key Laboratory of Advanced Functional Polymer Membrane Materials of Jilin Province

The development of alkaline fuel cells is moving forward at an accelerated pace,and the application of ether-free bonded polymers to anion exchange membranes （AEMs） has been widely ***,the question of the“trade-off”between AEM ionic conductivity and dimensional stability remains *** strategy of inducing microphase separation to improve the performance of AEM has attracted much attention recently,but the design of optimal molecular structures is still being ***,this work introduced different ratios of 3-bromo-1,1,1-trifluoroacetone （x=40,50,and 60） into the main chain of poly（p-terphenylene isatin）.Because fluorinated groups have excellent hydrophobicity,hydrophilic hydroxyl-containing side chains are introduced to jointly adjust the formation of phase separation *** results show that PTI-PTF50-NOH AEM with the appropriate fluorinated group ratio has the best ionic conductivity and alkali stability under the combined effect of *** has an ionic conductivity of 133.83 mS cm-1at 80°*** addition,the OH-conductivity remains at 89%of the initial value at 80°c and 3 M KOH for 1056 h of *** cell polarization curve based on PTI-PTF50-NOH shows a power density of 734.76 mW cm-2at a current density of 1807.7 mA cm-2.

关键词： Potassium hydroxide

Reversible Li2c2O4 product regulation in Li–cO2 batteries using single-atom alloy engineering

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Sc.ence china chemistry 2025年

作者： Xinxin Zhang yu Wang Yafei Li Jiangsu Key Laboratory of New Power Batteries Jiangsu Collaborative Innovation Centre of Biomedical Functional Materials School of Chemistry and Materials Science Nanjing Normal University

The effic.ency of lithium-carbon dioxide （Li–cO2） batteries is limited by the sluggish generation/decomposition kinetics of the discharge products （i.e.,Li2cO3and carbon） despite the use of state-of-the-art noble metal （NM） ***2c2O4has emerged as a promising alternative product;however,the thermodynamic instability of Li2c2O4causes it to generally appear as an intermediate in Li2cO3pathways rather than a product during ***,using comprehensive first-principles calculations,we report tailoring the discharge products of Li–cO2batteries to Li2c2O4via single-atom alloy （SAA） engineering,in which NM-doped copper SAAs （NM1cu） are constructed for *** NM1cu catalysts display a free-atom-like narrow d-band state and unique charge distribution over the solute NM1atom and the surrounding matrix cu *** an optimized electronic structure is substantial in Ru1cu and Ir1cu,which is conducive to the co-activation and coupling of *** lithiation of*cO2intermediate that breaks the charge symmetry of the central c species can further reduce the kinetic barriers of the c–c *** advantages promote Li2c2O4generation on Ru1cu and Ir1cu while suppress its subsequent ***,they exhibit low theoretical overpotentials and enable facile delithiation under normal charging *** work proposes a universal principle of manipulating electronic structures to achieve Li2c2O4product,which provides practical guidance for the development of Li–cO2batteries.

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