检索结果-南通市图书馆

Ji-Chuan decoction ameliorates slow transit constipation via regulation of intestinal glial cell apoptosis

World Journal of Gastroenterology 2022年第34期28卷 5007-5022页

作者： Xiu-Min Wang Li-Xia Lv yue-Si Qin yu-Zhu zhang Ni Yang Shu Wu Xiu-Wen Xia Hong Yang Hong Xu Ying Liu Wei-Jun Ding Department of Fundamental Medicine Chengdu University of Traditional Chinese MedicineChengdu 610072Sichuan ProvinceChina Department of Proctology Chengdu First People’s HospitalChengdu 610041Sichuan ProvinceChina Department of Endocrinology and Metabolism Chengdu First People’s HospitalChengdu 610041Sichuan ProvinceChina Department of Dermatology Chengdu First People’s HospitalChengdu 610041Sichuan ProvinceChina Department of Preventive Medicine Shantou University Medical CollegeShantou 515063Guangdong ProvinceChina

BACKGROUND Slow transit constipation(STC)is a common intestinal disease with increasing *** results from various factors,such as the enteric nervous system and metabolic *** a classical formula of traditional Chinese medicine,Ji-Chuan decoction(JCD)has been extensively and effectively used in STC treatment,yet its pharmacological mechanism remains *** To explore the integrated regulatory pattern of JCD against STC through hyphenated techniques from metabolism,network pharmacology and molecular *** STC model mice were generated by intragastric administration of compound diphenoxylate(10 mg/kg/d)for 14 *** STC mice in the low dose of JCD(3.04 g/kg),middle dose of JCD(6.08 g/kg)and high dose of JCD(12.16 g/kg)groups were orally administered JCD solution once a day for 2 *** acetylcholine(ACH)level was examined by enzyme-linked immunosorbent *** pathological features of colon tissue were observed by hematoxylin and eosin *** differentially expressed metabolites and metabolic pathways were tested by nontargeted *** main targets and core ingredients of JCD were identified by network pharmacology,and the expression of AKT was confirmed by ***,the pathways involved in JCD treatment were predicted using a combination of differentially expressed metabolites and targets,and intestinal glial cell apoptosis was demonstrated by *** JCD significantly promoted intestinal motility,increased the levels of the excitatory neurotransmitter ACH and reduced intestinal inflammation in STC *** metabolomics results showed that JCD significantly restored metabolic dysfunction and significantly affected taurine and hypotaurine *** pharmacology and molecular experiments showed that JCD regulates AKT protein expression,and the core component is *** analysis demonstrated that apoptosis may be an important mechanism by which JCD relieves co

关键词： Slow-transit constipation Ji-Chuan decoction Taurine and hypotaurine metabolism AKT Enteric glial cell Apoptosis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tree-ring δ^(15)N of Qinghai spruce in the central Qilian Mountains of China:Is pre-treatment of wood samples necessary?

引用

Journal of Arid Land 2022年第6期14卷 673-690页

作者： WANG Ziyi LIU Xiaohong WANG Keyi ZENG Xiaomin zhang yu GE Wensen KANG Huhu LU Qiangqiang School of Geography and Tourism Shaanxi Normal UniversityXi'an 710119China State Key Laboratory of Cryospheric Science Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000China Qilian Mountain National Park Research Center(Qinghai) Xining 810008China School of Earth System Science Tianjin UniversityTianjin 300072China

A knowledge of the tree-ring stable nitrogen isotope ratio(δ^(15)N)can deepen our understanding of forest ecosystem dynamics by indicating the long-term availability,cycling and sources of nitrogen(N).However,the radial mobility of N blurs the interannual variations in the long-term N *** studies of the chemical extraction of tree rings before analysis had produced inconsistent results and it is still unclear whether it is necessary to pre-treat wood samples from specific tree species to remove soluble N compounds before determining theδ^(15)N *** compared the effects of pre-treatment with organic solvents and hot ultrapure water on the N concentration andδ^(15)N of tree rings from endemic Qinghai spruce(Picea crassifolia)growing in the interior of the central Qilian Mountains,China,during the last 60 *** assessed the effects of different preparation protocols on the removal of the labile N compounds and investigated the need to pre-treat wood samples before determining theδ^(15)N values of tree *** trends of the tree-ring N concentration were consistently observed in both the extracted and unextracted wood *** total N removed by extraction with organic solvents was about 17.60%,with a significantly higher amount in the sapwood section(P<0.01).Theδ^(15)N values of tree rings decreased consistently from 1960 to 2019 in both the extracted and unextracted wood *** with organic solvents increased theδ^(15)N values markedly by about 5.2‰and reduced the variations in theδ^(15)N ***,extraction with hot ultrapure water had little effect,with only a slight decrease in theδ^(15)N values of about 0.5‰.Our results showed that the radial pattern in the inter-ring movement of N in Qinghai spruce was not minimized by extraction with either organic solvents or hot ultrapure *** is unnecessary to conduct hot ultrapure water extraction for the wood samples from Qinghai spruce because of its negligible effect on t

关键词： tree rings stable nitrogen isotope ratio(δ^(15)N) nitrogen concentration solvent-extracted wood water-extracted wood wood pre-treatment Qinghai spruce Qilian Mountains

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A novel technology of high-voltage pulse discharge for comminution of galena ore

引用

Transactions of Nonferrous Metals Society of China 2021年第8期31卷 2479-2492页

作者： Yong-hong QIN Peng GAO Shuai yuAN Ning-yu zhang Li-ren HAN College of Resources and Civil Engineering Northeastern UniversityShenyang 110819China National-local Joint Engineering Research Center of High-efficient Exploitation Technology for Refractory Iron Ore Resources Shenyang 110819China

An innovative technology of high-voltage pulse discharge(HVPD)was proposed to investigate the comminution characteristics of galena *** optimal experiment parameters were determined as follows:spark gap spacing of 25 mm,pulse number of 120,and voltage of 25 k *** mass fraction with size<0.074 mm in ground products was improved by the ***,the relative grindability declined with the increase of the grinding time,which indicated that the superiority of HVPD was *** ground products of HVPD were distributed more homogeneously than those of mechanical *** liberation of breakage products was improved by 24.57%via the ***,the Brunauer–Emmett–Teller(BET)specific surface area,pore volume,and average pore size were increased via the *** electron microscopy(SEM)and energy-dispersive X-ray spectroscopy(EDS)analyses suggested that obvious grain-boundary breakage and several stomatal traces were observed in the HVPD products.

关键词： galena ore high-voltage pulse discharge liberation microstructure grain-boundary breakage

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

调理剂对厨余垃圾堆肥中H2S和NH3排放的影响

引用

中国环境科学 2015年第11期35卷 3379-3386页

作者：张红玉张玉冬顾军李国学袁京北京建筑材料科学研究总院固废资源化利用与节能建材国家重点实验室北京100041 吉林农业大学吉林长春130118 中国农业大学资源与环境学院北京100193

为了降低厨余垃圾堆肥过程中H2S和NH3这2种恶臭物质的排放,通过向堆肥原料中添加玉米秸秆、木本泥炭和木屑3种调理剂,同时以厨余垃圾单独堆肥作为对照,研究调理剂添加对H2S和NH3排放的影响.结果表明,3种调理剂的添加均促进了有机物的降... 详细信息

为了降低厨余垃圾堆肥过程中H2S和NH3这2种恶臭物质的排放,通过向堆肥原料中添加玉米秸秆、木本泥炭和木屑3种调理剂,同时以厨余垃圾单独堆肥作为对照,研究调理剂添加对H2S和NH3排放的影响.结果表明,3种调理剂的添加均促进了有机物的降解和堆体的快速升温,与对照相比,使堆肥进入高温期的时间提前了3~4d;从电导率和发芽率指数来看,添加玉米秸秆处理的堆肥产品达到完全腐熟的要求,而添加木本泥炭和木屑处理的堆肥产品只是达到了无害化的要求;3种调理剂的添加均不同程度减少了厨余垃圾堆肥中H2S和NH3的排放,与对照相比,添加玉米秸秆、木本泥炭和木屑使厨余垃圾堆肥中H2S的累积排放量分别降低了78.7%,50.3%和89.8%,NH3的累积排放量分别降低了53.8%、87.7%和63.9%,可见木屑更能有效控制H2S的排放,而木本泥炭更能有效控制NH3的排放.

关键词：厨余垃圾堆肥调理剂 H2S NH3

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

In-beam gamma rays of CSNS Back-n characterized by black resonance filter

引用

Nuclear Science and Techniques 2024年第10期35卷 149-160页

作者： Jin-Cheng Wang Jie Ren Wei Jiang Xi-Chao Ruan Ying-Yi Liu Hao-Lan Yang Kuo-Zhi Xu Xin-Yi Pan Qi Sun Jie Bao Han-Xiong Huang Hao-Fan Bai Jiang-Bo Bai Ping Cao Qi-Ping Chen Yong-Hao Chen Wen-Hao Duan An-Chuan Fan Rui-Rui Fan Chang-Qing Feng Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Zhi-Jie Jiang Ling Kang Chang-Lin Lan Bo Li Feng Li Qiang Li Xiao Li Yang Li Jie Liu Rong Liu Shu-Bin Liu Yi-Na Liu Guang-yuan Luan Chang-Jun Ning Yi-Jia Qiu Wen-Kai Ren Zhi-Zhou Ren Zhao-Hui Song Kang Sun Zhi-Xin Tan Jing-yu Tang Sheng-Da Tang Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen Xiao-Guang Wu Xuan Wu Ze-Peng Wu Cong Xia Li-Kun Xie Han Yi Tao yu Yong-Ji yu Guo-Hui zhang Hang-Chang zhang Qi-Wei zhang Xian-Peng zhang yu-Liang zhang Zhi-Yong zhang Mao-yuan Zhao Zhi-Hao Zhou Ke-Jun Zhu Chong Zou Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China School of Nuclear Science and Technology Lanzhou UniversityLanzhou 730000China Institute of Advanced Technology University of Science and Technology of ChinaHefei 230027China

The back-streaming white-neutron beamline(Back-n)of the China Spallation Neutron Source is an essential neutronresearch platform built for the study of nuclear data,neutron physics,and neutron *** types of cross-sectional neutron-reaction measurements have been performed at Back-n since early *** measurements have shown that a significant number of gamma rays can be transmitted to the experimental stations of Back-n along with the neutron *** gamma rays,commonly referred to as in-beam gamma rays,can induce a non-negligible experimental background in neutron-reaction *** the characteristics of in-beam gamma rays is important for understanding the experimental ***,measuring in-beam gamma rays is challenging because most gamma-ray detectors are sensitive to neutrons;thus,discriminating between neutron-induced signals and those from in-beam gamma rays is *** this study,we propose the use of the black resonance filter method and a CeBr_(3) scintillation detector to measure the characteristics of the in-beam gamma rays of *** types of black resonance filters,^(181)Ta,^(59)Co,^(nat)Ag,and^(nat)Cd,were used in this *** time-of-flight(TOF)technique was used to select the detector signals remaining in the absorption region of the TOF spectra,which were mainly induced by in-beam gamma *** energy distribution and flux of the in-beam gamma rays of Back-n were determined by analyzing the deposited energy spectra of the CeBr_(3) scintillation detector and using Monte Carlo *** on the results of this study,the background contributions from in-beam gamma rays in neutron-reaction measurements at Back-n can be reasonably evaluated,which is beneficial for enhancing both the experimental methodology and data analysis.

关键词： In-beam gamma rays Back-n CeBr_(3)scintillator Black filter resonance technique

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于Au@Pt纳米粒子-双亲性气凝胶的模拟酶可视化检测抗坏血酸

引用

分析化学 2021年第6期49卷 982-991页

作者：周晨雨房琦张玉杜衍中国科学院长春应用化学研究所电分析化学国家重点实验室中国科学技术大学应用化学与工程学院

采用水热法在双亲性聚乙烯醇气凝胶(PAA)载体上原位生长Au@Pt纳米粒子,制备Au@Pt-PAAC复合纳米材料。PAA载体上丰富的含氧基团为纳米粒子的生长提供了成核位点,而核壳结构的Au@Pt纳米粒子,一方面由于协同效应提高了材料的类氧化酶活性,... 详细信息

采用水热法在双亲性聚乙烯醇气凝胶(PAA)载体上原位生长Au@Pt纳米粒子,制备Au@Pt-PAAC复合纳米材料。PAA载体上丰富的含氧基团为纳米粒子的生长提供了成核位点,而核壳结构的Au@Pt纳米粒子,一方面由于协同效应提高了材料的类氧化酶活性,另一方面减少了铂的用量,降低了催化剂成本。基于Au@Pt-PAAC材料的类氧化酶活性构筑了比色传感器用于还原性物质抗坏血酸(AA)的可视化检测。在优化的实验条件下,检测AA的线性范围为10～100μmol/L,检出限为8.77μmol/L。将本方法用于饮料和维生素C片中的AA含量检测,所得实验结果与样品标示含量一致,因此可用于总抗氧化能力(TAC)的评价。本方法简单、直观、抗干扰能力强,具有良好的实用性。

关键词： Au@Pt纳米粒子氧化酶双亲性气凝胶比色分析抗坏血酸总抗氧化能力

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

蚕蛹蛋白质纤维/玉石纤维/丝光毛半精纺保健性AB纱的开发

引用

毛纺科技 2017年第5期45卷 15-17页

作者：张梅徐静张玉德州学院纺织服装学院山东德州253023

对蚕蛹蛋白质纤维、玉石纤维、丝光毛的特点进行分析,设计纺纱工艺,并探讨纺纱过程中的技术关键。蚕蛹蛋白质纤维柔软细腻,具有消除疲劳、回复肌肤活力、延缓肌肤衰老、抵御紫外线侵害的功能,玉石纤维具有保健、改善血液微循环、促进新... 详细信息

对蚕蛹蛋白质纤维、玉石纤维、丝光毛的特点进行分析,设计纺纱工艺,并探讨纺纱过程中的技术关键。蚕蛹蛋白质纤维柔软细腻,具有消除疲劳、回复肌肤活力、延缓肌肤衰老、抵御紫外线侵害的功能,玉石纤维具有保健、改善血液微循环、促进新陈代谢、凉爽、抗菌的功能,而且丝光毛具有良好的服用性能。借助半精纺纱技术和赛络纺纱工艺,纺制出绿色环保、外观独特的AB花式纱。该产品符合时代潮流,深受消费者喜爱,具有较高的经济效益和广阔的市场前景。

关键词：蚕蛹蛋白质纤维玉石纤维丝光毛半精纺保健性 AB纱

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An Integrated Carbon Dioxide Capture and Methanation Process

引用

CCS Chemistry 2024年第5期6卷 1174-1183页

作者： Xiaochen zhang Mengzhu Li Xingwu Liu Ang Li yuchen Deng Mi Peng yu zhang Charlotte Vogt Matteo Monai Junxian Gao Xuetao Qin Yao Xu Qiaolin yu Meng Wang Guofu Wang Zheng Jiang Xiaodong Han Casper Brady Wei-Xue Li Wu Zhou Jin-Xun Liu Bingjun Xu Bert M.Weckhuysen Ding Ma Beijing National Laboratory for Molecular Sciences College of Chemistry and Molecular EngineeringPeking UniversityBeijing 100871 China Academy of Aerospace Science and Innovation Beijing 100088 National Energy Center for Coal to Liquids Synfuels China Co.Ltd.Beijing 101400 Beijing Key Laboratory of Microstructure and Property of Advanced Materials Beijing University of TechnologyBeijing Inorganic Chemistry and Catalysis group Institute for Sustainable and Circular Chemistry and Debye Institute for Nanomaterials ScienceFaculty of ScienceUtrecht University3584 CG Utrecht State Key Laboratory of Coal Conversion Institute of Coal ChemistryChinese Academy of SciencesTaiyuan 030001 Shanghai Synchrotron Radiation Facility Zhangjiang LadShanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201210 Center for Catalytic Science and Technology University of DelawareNewarkDelaware 19716 Key Laboratory of Precision and Intelligent Chemistry School of Chemistry and Materials ScienceUniversity of Science and Technology of ChinaHefeiAnhui 230026 Hefei National Laboratory University of Science and Technology of ChinaHefei 230088 School of Physical Sciences CAS Key Laboratory of Vacuum PhysicsUniversity of Chinese Academy of SciencesBeijing 100049

Reducing the ever-growing level of CO_(2)in the atmosphere is critical for the sustainable development of human society in the context of global *** of the capture and upgrading of CO_(2)is,therefore,highly desirable since each process step is costly,both energetically and ***,we report a CO_(2)direct air capture(DAC)and fixation process that produces *** concentrations of CO_(2)(∼400 ppm)in the air are captured by an aqueous solution of sodium hydroxide to form *** carbonate is subsequently hydrogenated to methane,which is easily separated from the reaction system,catalyzed by TiO2-supported Ru in the aqueous phase with a selectivity of 99.9%among gas-phase *** concurrent regenerated hydroxide,in turn,increases the alkalinity of the aqueous solution for further CO_(2)capture,thereby enabling this one-ofits-kind continuous CO_(2)capture and methanation *** simulations demonstrate the energy feasibility of this CO_(2)DAC and methanation process,highlighting its promise for potential largescale applications.

关键词： CO_(2)capture and methanation process sodium hydroxide carbonate Ru/TiO_(2) catalytic mechanism CO_(2)activation and hydrogenation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

基于FastICA的P300电位快速提取方法

引用

华东理工大学学报（自然科学版） 2009年第5期35卷 750-755页

作者：张宇张建华王行愚金晶华东理工大学信息科学与工程学院上海200237

从两个方面研究了快速独立分量分析(Fast Independent Component Analysis,FastICA)方法在诱发脑电P300少次提取中的应用,并给出了针对健康和残疾被试的实验结果。首先,利用FastICA对观测信号进行去噪,然后对去噪后的P300分量进行较少... 详细信息

从两个方面研究了快速独立分量分析(Fast Independent Component Analysis,FastICA)方法在诱发脑电P300少次提取中的应用,并给出了针对健康和残疾被试的实验结果。首先,利用FastICA对观测信号进行去噪,然后对去噪后的P300分量进行较少次叠加平均,并对提取出的健康和残疾被试的P300特征进行了详细的比较分析;然后,从模式识别的角度出发,逐渐减少叠加次数,分别考察了根据提取出的P300特征进行靶刺激和非靶刺激识别的难易程度。实验结果表明了FastICA方法用于P300较少次提取的有效性。

关键词：快速独立分量分析脑电信号EEG 靶刺激残疾被试

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

HAT循环后冷湿化过程的传热传质性能研究

引用

热能动力工程 2023年第2期38卷 33-40页

作者：蒋将军王玉璋张琨羽张晴上海交通大学机械与动力工程学院上海200240

为了提升湿空气燃气轮机循环的调控灵活性,自主设计和搭建了后冷湿化器一体化实验系统,通过实验获得不同水气比下后冷湿化器出口空气的温湿度和出口水温,利用实验数据修正表面化学反应速率,基于表面化学反应模型建立了后冷湿化过程三维... 详细信息

为了提升湿空气燃气轮机循环的调控灵活性,自主设计和搭建了后冷湿化器一体化实验系统,通过实验获得不同水气比下后冷湿化器出口空气的温湿度和出口水温,利用实验数据修正表面化学反应速率,基于表面化学反应模型建立了后冷湿化过程三维数值模型,分析了水气比和进口水温对后冷湿化器性能的影响。结果表明:建立的后冷湿化器传热传质模型能高精度模拟后冷湿化过程,空气温度沿流动方向呈逐渐降低的趋势,空气的含湿量和相对湿度沿流动方向逐渐升高;水气比和进口水温均对后冷湿化器的性能有较大影响,随着水气比和进口水温增大出口空气湿度提高,湿化性能提升,而降低水气比有利于提升空气后冷性能。

关键词： HAT循环后冷湿化传热传质实验研究数值模拟

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：