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Intelligent interaction system based on multimodal conformal triboelectric nanogenerator patch for disabled sports and life

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Science China Technological Sciences 2025年

作者： yuzhang WEN Mengqi ZHANG Zhenning XIE Zida AN Bing LIU Fengxin SUN Tianming zhao Zuojun yu Fei WANG yupeng MAO Physical Education Department Northeastern University(Shenyang) Faculty of Robot Science and Engineering Northeastern University Criminal Investigation Police University of China State Key Laboratory of Robotics Shenyang Institute of Automation Chinese Academy of Sciences China Ice Sports College Beijing Sport University

Intelligent interaction technology based on advanced sensing units has become a research hotspot. In this paper, an intelligent interaction system (IIS) based on a multimodal conformal triboelectric nanogenerator patch (MCTP) is reported for sports monitoring and life promotion of the disabled. This IIS consists of a cloud-based smart sports recognition program and a smart life application. The porous micro-reinforced structure of polyurethane (PU) Sponge&Ecoflex, and the surface modification of PTFE by coating it with MXene endows the MCTP with excellent electrical properties. It shows good angle and force sensitivities of 1.1 V/°and 1.61 V/N, respectively, and has an ultra-fast response time of 15 ms, meeting the needs of human motion monitoring. The MCTP can also capture the mechanical energy, producing a maximum output power of 139μ*** with the commercial inertial measuring unit (IMU), the MCTP shows better consistency in human joint angle sensing. A precise analysis of wheelchair curling sports monitoring points is achieved by combining the MCTP and the human anatomy model. The cloud-based smart sports recognition program utilizes machine learning to achieve visual feedback on the three throwing technologies of draw, takeout and clearing. In addition, the developed smart life application uses a highsensitivity MCTP-sensor array design to achieve a variety of smart home interactions through simple finger touches. Overall,the IIS integrates the three major functions of smart sports sensing, energy capture, and smart home control, providing important application prospects in the fields of smart sports and human-computer interaction for the disabled.

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Pulsed dynamic electrolysis enhanced PEMWE hydrogen production:Revealing the effects of pulsed electric fields on protons mass transport and hydrogen bubble escape

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Journal of Energy Chemistry 2025年第1期100卷 201-214页

作者： Xuewei Zhang Wei Zhou yuming Huang Liang Xie Tonghui Li Huimin Kang Lijie Wang Yang yu Yani Ding Junfeng Li Jiaxiang Chen Miaoting Sun Shuo Cheng Xiaoxiao Meng Jihui Gao Guangbo zhao School of Energy Science and Engineering Harbin Institute of Technology China Datang Technology Innovation Co. Ltd

The transition of hydrogen sourcing from carbon-intensive to water-based methodologies is underway,with renewable energy-powered proton exchange membrane water electrolysis （PEMWE） emerging as the preeminent pathway for hydrogen *** remarkable advancements in this field,confronting the sluggish electrochemical kinetics and inherent high-energy consumption arising from deteriorated mass transport within PEMWE systems remains a formidable *** impediment stems primarily from the hindered protons mass transfer and the untimely hydrogen bubbles *** address these challenges,we harness the inherent variability of electrical energy and introduce an innovative pulsed dynamic water electrolysis *** to constant voltage electrolysis (hydrogen production rate:51.6 m L h-1,energy consumption:5.37 kWh Nm-3H2),this strategy (hydrogen production rate:66 m L h-1,energy consumption:3.83 kWh Nm-3H2) increases the hydrogen production rate by approximately 27%and reduces the energy consumption by about 28%.Furthermore,we demonstrate the practicality of this system by integrating it with an off-grid photovoltaic （PV） system designed for outdoor operation,successfully driving a hydrogen production current of up to 500 mA under an average voltage of approximately 2 *** combined results of in-situ characterization and finite element analysis reveal the performance enhancement mechanism:pulsed dynamic electrolysis （PDE） dramatically accelerates the enrichment of protons at the electrode/solution interface and facilitates the release of bubbles on the electrode *** such,PDE-enhanced PEMWE represents a synergistic advancement,concurrently enhancing both the hydrogen generation reaction and associated transport *** promising technology not only redefines the landscape of electrolysis-based hydrogen production but also holds immense potential for broadening its application across a diverse spectrum of electrocatalytic endeavors.

关键词： Electrolysis

Demyelinating encephalopathy in patients following allogeneic hematopoietic stem cell transplantation:a retrospective analysis of incidence,risk factors and survival

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Demyelinating encephalopathy in patients following allogenei...

Lipomatous ependymoma with ZFTA:RELA fusion-positive:A case report

第13届全国实验血液学会议

作者： Zhang Xiaohui,Huang Xiaojun,Liu Kaiyan,Xu Lanping,Liu Daihong,Chen Huan,Han Wei,Chen yuhong,Wang Fengrong,Wang Jingzhi,Wang yu,zhao ting,Chen Yao, Fu Haixia,Feng Ru Peking University,Institute of Hematology,Beijing 100044

＜正＞The incidence of demyelinating encephalopathy complications,their risk factors,and impact on outcome are not well defined in recipients of allogeneic heniatopoietic stem cell transplant（allo-HSCT）.We analyzed a large cohort of 1365 patients who underwent allogeneic HSCT during a 6-year period and identified 36 patients who experienced demyelinating encephalopathy at the Institute of Hematology and People’ s Hospital,Peking University between 2004 and *** cumulative incidences of all demyelinating encephalopathy complications at 6-year was 3.6%.One patient（2.8%） had demyelinating encephalopathy at the conditioning stage,the other 35 patients had them after transplantation,16[44.4%]at day 0 to day 100,10 [27.8%]at day 100 to 1 year,and 9[25.0%]after 1 year.

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来源： cnki会议评论

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World Journal of Clinical Cases 2025年第1期13卷 48-55页

作者： Xiao-yu zhao Juan-Han yu Yi-Hua Wang Yi-Xin Liu Lu Xu Lin Fu Ning Yi China Medical University The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Department of Pathology The First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina Anshan Cancer Hospital Anshan 114000Liaoning ProvinceChina

BACKGROUND Ependymoma with lipomatous differentiation is a rare type of *** ZFTA fusion-positive supratentorial ependymoma is a novel tumor type in the 2021 World Health Organization classification of central nervous system *** fusion-positive lipomatous ependymoma has not been reported to *** SUMMARY We reported a case of a 15-year-old Chinese male who had a sudden convulsion lasting approximately six *** resonance imaging showed a round cystic shadow of approximately 1.9 cm×1.5 cm×1.9 cm under the right parieto-occipital *** examination showed characteristic perivascular pseudorosettes and adipose differentiation in the ***-chemical staining showed that the tumor cells were negative for cytokeratin,NeuN,Syn and p53,but positive for GFAP,vimentin and S-100 ***-ficant punctate intracytoplasmic EMA immunoreactivity was *** level of Ki-67 was about 5%.Genetic analysis revealed ZFTA:RELA fusion.A cranio-tomy with total excision of the tumor was *** follow-up time was 36 months,no evidence of disease recurrence was found in magnetic resonance *** Based on these findings,the patient was diagnosed as a ependymoma with ZFTA fusion and lipomatous *** case report provides information on the microscopic morphological features of ependymoma with ZFTA fusion and lipomatous differentiation,which can help pathologists to make a definitive diagnosis of this tumor.

关键词： Ependymoma Lipomatous Molecular classification Supratentorial ZFTA:RELA fusion Case report

Unveiling phosphofructokinase as the key target: an innovative strategy combining pull-down assays with optical imaging for snail-killing mechanism exploration

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Science China Chemistry 2025年

作者： yuxun Lu Weisi Wang Le yu yuqiang zhao Ying Chen yunhai Guo Bingrong Luo yuhua Liu Shizhu Li Liping Duan Ying Zhou yunnan Characteristic Plant Extraction Laboratory College of Chemical Science and Technology Yunnan University College of Biological and Chemical Engineering Guangxi University of Science and Technology National Institute of Parasitic Diseases Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector Biology WHO Collaborating Centre for Tropical Diseases National Center for International Research on Tropical Diseases School of Chemistry and Environment Yunnan Minzu University Dali Institute of Schistosomiasis Control

The Pomacea canaliculata, also known as apple snail, is an invasive species in China, posing a serious threat to agricultural production and public health. To prevent its rampant infestation, we developed a highly efficient snail-killing lead compound, 1-(4-chlorophenyl)-3-(pyridin-3-yl)urea (PBQ). However, the killing mechanism of PBQ remains unclear. To elucidate this, two novel compounds, B-PBQ and J-PBQ, were developed through structural modification of PBQ and were used, through both protein pull-down assay and confocal laser scanning microscopy imaging, to identify and confirm that phosphofructokinase(PFK) in the apple snail is the primary target protein of PBQ. Further studies revealed that PBQ successfully inhibits the activity,content, and expression of PFK in apple snail, disrupting the glycolysis pathway and leading to abnormal energy *** disruptions impair the snail’s tolerance to low oxygen, resulting in its efficient eradication. These findings offer a promising direction for developing next-generation PFK-targeted snail-killing pesticides. Furthermore, the strategy of combining pull-down assays with optical imaging used in this work provides a novel approach for the exploration of mechanisms of other pesticide candidates.

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Metastable seed-crystals: epitaxial growth of branched-array organic heterostructure nanowires

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Science China Chemistry 2025年

作者： Jin Feng Zhen-yu Geng ting-Yao Song Ying-Xin Ma Chuan-Zeng Wang Wei Zhang Hong-Tao Lin Jin Zhou Shu-Ping Zhuo Shu-Hai Chen Xue-Dong Wang School of Chemistry and Chemical Engineering Shandong University of Technology Institute of Functional Nano & Soft Materials (FUNSOM) Jiangsu Key Laboratory for Carbon-Based Functional Materials & DevicesSoochow University College of Chemistry and Chemical Engineering Hunan Normal University

Tunable light–matter interactions are exhibited by organic low-dimensional crystals, making these crystals a promising platform for organic photonics. However, the precise synthesis of organic low-dimensional crystals remains challenging due to the stochastic nature of molecular nucleation processes. Herein, the directed nucleation process is driven by the introduction of metastable seed-crystals as the trunk, which ultimately leads to branched-array organic heterostructures. The successful formation of organic heterostructures with high-density branched arrays is attributed to the highest attachment energy (Eatt（023）=-104.25 kcal mol-1) of the exposed （023） crystal plane during the seed-crystal growth route. Significantly, these as-prepared heterostructures inherently have an ultralow lattice mismatch ratio η of 0.7%between trunk and branch, which contributes to the multi-channel photon transportation. Therefore, this work provides valuable insights into a versatile synthetic strategy for accessing low-dimensional heterostructures for integrated optoelectronics.

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A stretchable, ionic conductive, and adhesive patch electrode with ultra-low on-skin impedance for electrophysiological signal recording

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Science China(Information Sciences) 2025年

作者： Yang LI yuzhe GU Sheng QIAN yuncong PANG Aoxi yu Shuwen ZHENG Wenjie XIA yuan LIAO Baoguang LIU Shujuan LIU Qiang zhao College of Electronic and Optical Engineering & College of Flexible Electronics (Future Technology) Nanjing University of Posts & Telecommunications (NJUPT) State Key Laboratory of Organic Electronics and Information Displays & Jiangsu Key Laboratory for Biosensors Institute of Advanced Materials (IAM) Nanjing University of Posts & Telecommunications (NJUPT)

Flexible electrodes have significant potential in fields such as healthcare and neuroscience, as they enable comprehensive recording and analysis of human electrical signals, providing deeper insights into physiological conditions and the state of internal organs and tissues [1, 2]. However, commercial Ag/AgCl wet electrodes face issues such as dehydration,poor comfort, and insufficient mechanical strength, while other types of electrodes, like dry and semi-dry electrodes,also have their own limitations, including the higher contact impedance. In contrast, ionically conductive electrodes offer potential advantages such as transparency, stability, and low impedance, making them a promising alternative to existing electrically conductive electrodes [3]. Acrylic acid (AA)and 2-acrylamido-2-methylpropanesulfonic acid (AMPS) are commonly used in the synthesis of ionic gels, as they ionize in water to produce a large number of ions, helping to maintain moisture balance and reduce impedance caused by dehydration [4]. However, the presence of freely moving ions in the gel network can interfere with conductivity, highlighting the need to introduce new conductive networks to enhance performance [5].

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Effects of Neuregulins on Invasion and Metastasis of Non-overexpression ErbB2 Breast Cancer Cells

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Chinese Journal of Cancer Research 2009年第2期21卷 115-121页

作者： Ya-mei Zhang ting-ting zhao Hua-yu Deng Laboratory of Stem Cell and Tissue Engineering Chongqing Medical University Chongqing 400016 China

Objective： To explore the effects of neuregulins on ErbB2 receptor signal transduction pathway activation, and invasion and metastasis of non-overexpression ErbB2 breast cancer cell MDA-MB-231. Methods： The expressions of neuregulin were detected by immunocytochemistry and Western blot. MDA-MB-231 cells were treated with ErbB2 kinase inhibitor AG825. Proliferations were measured with MTT assay. Invasion and metastasis of MDA-ME-231 cells were evaluated with transwell chamber. The enzyme activities of MMP-2 and MMP-9 were detected by gelatin zymography. The expressions of MMP-2 and HIF-1α were detected by Western blot. Results： MDA-MB-231 cells expressed a relatively higher level of neuregulin. In Western blot, the positive reaction band was found at 44KD which coincides with the molecular weight of NRG. When MDA-MB-231 cells were treated with AG825, the proliferation was inhibited in a time-dose-dependent manner （P〈0.01）, invasion and metastasis were also depressed （P〈0.05）. The enzyme activities of MMP-2 and MMP-9 were lower （P〈0.05）. The expression levels of MMP-2 and HIF-lct were decreased （P〈0.05）. Conclusion： Our study indicates that neuregulins are synthesized in MDA-MB-231 cells as transmembrane proteins, neuregulins could activate ErbB2 receptor signal transduction pathway by autocrine or paracrine secretion, and induce invasion and metastasis of MDA-MB-231 cells.

关键词： Non-overexpression ErbB2 breast cancer Neuregulins Invasion Metastasis

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不同烫漂方式及冷冻速率对预制西兰花质构品质的影响

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食品科学 2025年第1期46卷 121-130页

作者：赵伊诺金鑫毕金峰谢意通杜婷天津科技大学食品科学与工程学院天津300457 中国农业科学院农产品加工研究所农业农村部农产品加工重点实验室北京100193 沈阳农业大学食品学院辽宁沈阳110866

为探究预制西兰花加工过程中烫漂方式及冷冻速率对西兰花质构品质的影响,对经2种烫漂方式(热水烫漂、蒸汽烫漂)及3种冷冻温度(-20、-40、-80℃)处理的西兰花样品,利用低场核磁共振、理化特性分析方法测定不同处理组样品的水分分布、持... 详细信息

为探究预制西兰花加工过程中烫漂方式及冷冻速率对西兰花质构品质的影响,对经2种烫漂方式(热水烫漂、蒸汽烫漂)及3种冷冻温度(-20、-40、-80℃)处理的西兰花样品,利用低场核磁共振、理化特性分析方法测定不同处理组样品的水分分布、持水性、相对电导率和硬度,观察微观结构。结果表明:维持西兰花硬度的最佳工艺为蒸汽烫漂后进行-40℃冷冻,在此工艺条件下,与对照组相比,处理组西兰花水分分布中结合水峰面积占比(A21)增加最多、持水性最强,花序部分保留66.72%硬度、茎部分保留62.53%硬度,相对电导率增加至87.01%;通过扫描电子显微镜观察发现,经过该处理的西兰花保持了较好的细胞结构。本研究得到了有效维持解冻西兰花质构的工艺,并揭示了不同处理对西兰花水分分布及细胞膜完整性影响的机制,为实际生产过程保持冷冻预制西兰花品质提供了理论与技术支撑。

关键词：预制西兰花持水性水分迁移质构

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