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Acta Metallurgica Sinica(English Letters) 2022年第5期35卷 745-756页

作者： yu-Qing mao Ping Yang Li-Ming Ke Yang Xu yu-Hua Chen National Defence Key Discipline Laboratory of Light Alloy Processing Science and Technology Nanchang Hangkong UniversityNanchang330063China

Four tools with different pin centerline deviations were fabricated to friction stir weld(FSW)thick plates of Al-Mg-Zn-Cu *** results show that,compared with the pin without pin centerline deviation,the applying of pin centerline deviation is favorable to improve the flowability of plastic material,enlarging the size of nugget zone,refining the grains and reprecipitated phase particles,enhancing the degrees of dynamic recrystallization and quantity of high angle grain boundaries owing to higher temperature and bigger eccentric force,resulting in the increase of strain *** for the used pin with a centerline deviation of 0.2 mm,the highest average hardness and best metallurgical properties of thick FSW joints are produced,and which are consistent with the microstructure evolution and recrystallization ***,the fracture mode of the joints produced by the pins with centerline deviation from 0 mm to 0.3 mm changes gradually from a brittle fracture in the nugget zone(NZ)to a ductile failure in the HAZ.

关键词： Thick Al-Mg-Zn-Cu alloys Friction stir welding Pin centerline deviation Microstructure evolution Recrystallization behavior

Distinctive impacts of atmospheric intraseasonal oscillations on the net ecosystem exchange of the southeastern China forest between spring and summer

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Advances in Climate Change Research 2022年第5期13卷 700-709页

作者： Jian-Ying LI Jiang-yu mao Jong-Seong KUG Pan-mao ZHAI State Key Laboratory of Severe Weather(LASW)and Institute of Climate System Chinese Academy of Meteorological SciencesBeijing 100081China State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics(LASG) Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Division of Environmental Science and Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673South Korea

The southeastern China(SEC)forest is an important terrestrial biospheric carbon sink in the global carbon cycle,with its total net ecosystem exchange(NEE)accounting for about 3.2%of the global forest *** prevailing atmospheric intraseasonal oscillations(ISOs)over East Asia strongly modulate climatic conditions over the SEC during spring and summer,thus leading to significant ISOs in the NEE of the SEC *** atmospheric ISOs show strong seasonality,this study examined the distinctive impacts of atmospheric ISOs on the NEE of the SEC forest between spring and *** spring,the vertical coupling of 10–30-d atmospheric ISOs in the lower and upper troposphere leads to strong 10‒30-d ISOs of solar radiation and temperature over the *** 10‒30-d ISOs of solar radiation and temperature further result in the 10‒30-d ISOs of gross primary productivity(GPP)and terrestrial ecosystem respiration(TER).With the covariation in GPP and TER,the NEE of the SEC forest exhibits significant 10‒30-d *** contrast,the intraseasonal variations in climatic conditions over the SEC are associated with the 15‒60-d tropical atmospheric ISO during *** the induced 15‒60-d ISO of solar radiation leads to that of GPP,the induced 15‒60-d ISO of temperature is small and less effective;thus,the 15‒60-d ISO of NEE mainly originates from that of GPP.

关键词： Intraseasonal oscillation Southeastern China forest Carbon fluxes Global carbon cycle

Extending the Eigenvector 1 space to the optical variability of quasars

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Chinese Journal of Astronomy and Astrophysics 2009年第5期9卷 529-537页

作者： yu-Feng mao Jing Wang Jian-Yan Wei National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China Graduate University of Chinese Academy of Sciences Beijing 100049 China

We introduce a new physical parameter, the optical variability amplitude, to the well-established Eigenvector 1 space of quasars and test a sample of long-term B- band light curves of 42 Palomar-Green quasars monitored by Giveon et al. We find that the optical variability amplitude strongly correlates with the intensity ratio of FeⅡ to Hβ, Hβ width and peak luminosity at 5007A. We briefly discuss the physical meaning of our findings and suggest that the Eddington ratio may be a key factor in determining a quasar＇s variability.

关键词： galaxies active -- quasars general

Impacts of meteorological parameters and emissions on decadal,interannual, and seasonal variations of atmospheric black carbon in the Tibetan Plateau

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Advances in Climate Change Research 2016年第3期7卷 123-131页

作者： mao yu-Hao LIAO Hong State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry (LAPC) Institute of Atmospheric Physics Chinese Academy of Sciences School of Environmental Science and Engineering Nanjing University of Information Science and Technology

We quanti?ed the impacts of variations in meteorological parameters and emissions on decadal, interannual, and seasonal variations of atmospheric black carbon(BC) in the Tibetan Plateau for 1980-2010 using a global 3-dimensional chemical transport model driven by the Modern Era Retrospective-analysis for Research and Applications(MERRA) meteorological ?elds. From 1980 to 2010, simulated surface BC concentrations and all-sky direct radiative forcing at the top of the atmosphere due to atmospheric BC increased by 0.15 μg m^(-3)(63%) and by 0.23 W m^(-2)(62%), respectively, averaged over the Tibetan Plateau(75-105°E, 25-40°N). Simulated annual mean surface BC concentrations were in the range of 0.24-0.40 μg m^(-3) averaged over the plateau for 1980-2010, with the decadal trends of 0.13 μg m^(-3)per decade in the 1980 s and 0.08 in the 2000 s. The interannual variations were -5.4% to 7.0% for deviation from the mean, 0.0062 μg m^(-3) for mean absolute deviation, and 2.5% for absolute percent departure from the mean. Model sensitivity simulations indicated that the decadal trends of surface BC concentrations were mainly driven by changes in emissions, while the interannual variations were dependent on variations of both meteorological parameters and emissions. Meteorological parameters played a crucial role in driving the interannual variations of BC especially in the monsoon season.

关键词： Black carbon Tibetan Plateau Interannual variations South Asian summer monsoon

Proliferation of L02 human hepatocytes in tolerized genetically immunocompetent rats

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World Journal of Gastroenterology 2008年第15期14卷 2329-2337页

作者： Hu Lin Qing mao yu-Ming Wang Li Jiang Institute of Infectious Disease Southwest Hospital the Third Military Medical University Chongqing 400038 China

AIM: To investigate whether human hepatocytes could proliferate after transplantation to normal immunocompetent rats treated with 2-acetaminofluorene or Retrorsine and partial hepatectomy. METHODS: L02 hepatocyte-tolerant Sprague-Dawley rats were injected with Retrorsine, 2-acetaminofluorene or normal saline. L02 hepatocytes were then transplanted via the spleen. Human albumin and its mRNA, specific proliferating cell nuclear antigen (PCNA), L02 hepatocyte dynamic distribution, number density and area density of PCNA-positive cells in the liver were determined. RESULTS: All the examined indicators were not significantly different between the rats treated with 2-acetaminofluorene and normal saline, which was not the case with rats treated with Retrorsine. A dynamic distribution of L02 hepatocytes in the rat liver was detected from wk 1 to mo 6 after transplantation in the Retrorsine group and from wk 1 to 10 in the 2-acetaminofluorene group. Human albumin and its mRNA were detected from wk 2 to mo 6 in the Retrorsine group and from wk 1 to 8 in the 2-acetaminofluorene group. Specific human PCNA was detected in the rat liver from wk 2 to mo 6 in the Retrorsine group and from wk 2 to 6 in the 2-acetaminofluorene group. Human albumin and its mRNA contents as well as the number of PCNA positive cells reached a peak at wk 4. CONCLUSION: L02 human hepatocytes could not proliferate significiantly after transplantation to the normal, immunocompetent rats treated with 2-acetaminofluorene.L02 human hepatocytes can survive for 10 wk after transplantation and express human albumin for 8 wk. L02 human hepatocytes can proliferate and express human albumin for 6 mo after transplantation to the rats treated with Retrorsine. The chimeric L02 human hepatocytes, which then underwent transplantation into tolerant rats, were normal in morphogenesis, biochemistry and function.

关键词： Hepatocyte Chimerism Rat Transplantation Proliferation

Iron oxide nanoparticles:A promising approach for diagnosis and treatment of cardiovascular diseases

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Nano Research 2023年第11期16卷 12453-12470页

作者： Xue Bao yu mao Guangxiang Si Lina Kang Biao Xu Ning Gu Cardiovascular Disease Research Center Nanjing Drum Tower HospitalAffiliated Hospital of Medical SchoolMedical SchoolNanjing UniversityNanjing 210093China State Key Laboratory of Bioelectronics Jiangsu Key Laboratory for Biomaterials and DevicesSchool of Biological Sciences and Medical EngineeringSoutheast UniversityNanjing 210096China

Despite advances in diagnostic and therapeutic technologies for cardiovascular diseases(CVDs),it remains a leading cause of mortality and morbidity *** underscores the urgency for innovative approaches aiming at early and precise detection and treatment of CVDs to reduce the disease *** oxide nanoparticles(IONPs),with their unique magnetism and bioproperties,have shown great potential in this *** this review,we will begin with a brief overview of the synthesis and properties of *** will then focus on the latest applications of IONPs in CVDs,including diagnosis and *** use of IONPs in the integration of diagnosis and treatment for CVDs is a promising field,and will be addressed in a separate *** translational potential and challenges of IONPs will also be *** conclusion,ongoing research and development of IONP-based strategies are highly likely to address current challenges effectively,and offer more personalized and efficient options for the diagnosis and treatment of CVDs.

关键词： atherosclerosis cardiovascular disease diagnosis iron oxide nanoparticles theranostic treatment

Quantitative evaluation and spatial differentiation of eco-environmental livability in Zhejiang Province, China

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Journal of Mountain Science 2020年第6期17卷 1491-1508页

作者： WANG Yi ZHU Ying-ming yu mao-jun XU Jing School of Economics and Management Nanjing University of Science and TechnologyNanjing 210094China Industrial Cluster Decision-making Consulting Research Base in Jiangsu Nanjing 210094China Anhui Institute of Economics Hefei 230051China Tourism and Social Administration College Nanjing Xiaozhuang UniversityNanjing 211171China

The scientific analyses of the spatial patterns of regional eco-environment livability,along with the explorations of the correlations between ecoenvironments and population and economic activity distributions,are of major significance in the guidance of the coordinated development between social economies,natural resources,and *** this study,the topography,climate,hydrology,land cover,air quality,and the dangers presented by natural hazards in the study area were investigated in order to establish an evaluation model for the regional eco-environmental ***,the observed spatial patterns and regional differences in the eco-environmental livability,as well as their relationships with the distributions of population and economic activities in Zhejiang Province,were *** results showed that the ecoenvironmental livability in Zhejiang Province displayed a gradual decreasing trend from southwest to northeast,as well as from the mountains to the hills,valleys,and plains *** the compartmentalization of the eco-environmental livability,it was observed that the lowest livable area covered the largest population,accounting for approximately 29.64%of the total population in the study *** higher livable areas covered the widest land areas,accounting for approximately 26.15%of the total ***,it was found that the eco-environmental livability in the mountain areas was higher than that in the plain areas in Zhejiang ***,the ecoenvironmental livability was found to have a significant exponential relationship with the population and GDP densities of Zhejiang Province,with the R^2 of the curve-fittings reaching 0.835 and 0.656,***,it was determined that the coefficient of the exponential function was negative,which indicated that a strong negative relationship existed between the eco-environmental livability and densities of the population and economic *** was assumed that the impacts

关键词： Eco-environment Livability Quantitative evaluations Spatial differentiation Zhejiang Province

Up-regulation of HCN2 channels in a thalamocortical circuit mediates allodynia in mice

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National Science Review 2023年第2期10卷 107-122页

作者： Jun-Ma yu Rui Hu yu mao Yingju Tai Sen Qun Zhi Zhang Danyang Chen Yan Jin Department of Anesthesiology The Third Affiliated Hospital of Anhui Medical University (The First People's Hospital of Hefei) Department of Anesthesiology The First Affiliated Hospital of Anhui Medical University Department of Biophysics and Neurobiology Division of Life Sciences and Medicine University of Science and Technology of China Stroke Center and Department of Neurology The First Affiliated Hospital of USTC Division of Life Sciences and Medicine University of Science and Technology of China

Chronic pain is a significant problem that afflicts individuals and society,and for which the current clinical treatment is *** addition,the neural circuit and molecular mechanisms subserving chronic pain remain largely *** we identified enhanced activity of a glutamatergic neuronal circuit that encompasses projections from the ventral posterolateral nucleus(VPLGlu) to the glutamatergic neurons of the hindlimb primary somatosensory cortex(S1HLGlu),driving allodynia in mouse models of chronic *** inhibition of this VPLGlu→S1HLGlucircuit reversed allodynia,whereas the enhancement of its activity provoked hyperalgesia in control *** addition,we found that the expression and function of the HCN2(hyperpolarization-activated cyclic nucleotide-gated channel 2) were increased in VPLGluneurons under conditions of chronic *** in vivo calcium imaging,we demonstrated that downregulation of HCN2 channels in the VPLGluneurons abrogated the rise in S1HLGluneuronal activity while alleviating allodynia in mice with chronic *** these data,we propose that dysfunction in HCN2 channels in the VPLGlu→S1HLGluthalamocortical circuit and their upregulation occupy essential roles in the development of chronic pain.

关键词： chronic pain HCN2 channels neural circuit in vivo recordings

Pleomorphic lipoma in the anterior mediastinum: A case report

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World Journal of Clinical Cases 2019年第18期7卷 2899-2904页

作者： yu-Qiang mao Xiao-Ying Liu yun Han Department of Thoracic Surgery Shengjing Hospital of China Medical UniversityShenyang 110004Liaoning ProvinceChina Department of Plastic Surgery the First Hospital of China Medical UniversityShenyang 110001Liaoning ProvinceChina

BACKGROUND Pleomorphic lipoma (PL) is a rare benign mesenchymal tumor occurring predominantly in middle-aged and elderly men. It is typically found in the subcutaneous tissue of the posterior neck, back, and shoulders. There have also been a few reported cases in the face, scalp, and upper extremities. Currently, there is no report on its occurrence in the anterior mediastinum. CASE SUMMARY Herein, we report the case of a 67-year-old woman diagnosed with PL in the anterior mediastinum. The tumor was removed by thoracoscopic surgery. There was no recurrence during the 24-mo follow-up period, and the prognosis was good. Most PL are located on the skin surface. However, they may also occur within the body, even in the mediastinum. CONCLUSION PL occurring in the anterior mediastinum is rare, and it may be differentiated from other tumors.

关键词： Pleomorphic lipoma Anterior mediastinum Thoracoscopic surgery Case report

Research on Hydrodynamic Interference Suppression of Bottom-Mounted Monitoring Platform with Fairing Structure

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China Ocean Engineering 2018年第1期32卷 51-61页

作者： WANG Zhen ZHENG Yi mao yu-feng WANG Ya-zhou yu Yan-ting LIU Hong-ning Institute of Oceanographic Instrumentation Qilu University of Technology(Shandong Academy of Sciences)Qingdao 266061China Shandong Provincial Key Laboratory of Ocean Environmental Monitoring Technology Qingdao 266061China National Engineering and Technological Research Center of Marine Monitoring Equipment Qingdao 266061China

In the disturbance of unsteady flow field under the sea, the monitoring accuracy and precision of the bottom-mounted acoustic monitoring platform will decrease. In order to reduce the hydrodynamic interference, the platform wrapped with fairing structure and separated from the retrieval unit is described. The suppression effect evaluation based on the correlation theory of sound pressure and particle velocity for spherical wave in infinite homogeneous medium is proposed and the difference value between them is used to evaluate the hydrodynamic restraining performance of the bottom-mounted platform under far field condition. Through the sea test, it is indicated that the platform with sparse layers fairing structure(there are two layers for the fairing, in which the inside layer is 6-layers sparse metal net, and the outside layer is 1-layer polyester cloth, and then it takes sparse layers for short) has no attenuation in the sound pressure response to the sound source signal, but obvious suppression in the velocity response to the hydrodynamic noise. The effective frequency of the fairing structure is decreased below 10 Hz, and the noise magnitude is reduced by 10 d B. With the comparison of different fairing structures, it is concluded that the tighter fairing structure can enhance the performance of sound transmission and flow restraining.

关键词： bottom-mounted fairing hydrodynamic interference acoustic impedance transmission loss