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Effect of two different doses of intravitreal bevacizumab with temporal retina-sparing laser photocoagulation for retinopathy of prematurity

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International Journal of Ophthalmology(English edition) 2018年第1期11卷 166-169页

作者： A Young choi Hochan cho yu Cheol Kim Department of Ophthalmology Keimyung University School of Medicine Dongsan Medical Center Department of Internal Medicine Keimyung University School of Medicine Dongsan Medical Center

This study aims to compare the efficacy and safety between two different doses of intravitreal bevacizumab（IVB） injection with temporal retina-sparing laser（TRSL） photocoagulation for retinopathy of prematurity（ROP）. We retrospectively evaluated 22 eyes of ROP infants who underwent IVB combined with partial TRSL for stage 3＋ zone I or posterior zone II ROP. Laser photocoagulation was applied on the avascular retina, sparing two-discdiameter width temporal avascular area anterior to ridge. A half dose（0.625 mg） or minimal dose（0.25 mg） of IVB was conducted. Four eyes in minimal dose group were retreated with IVB and laser photocoagulation on the spared retina. Of those 4 retreated eyes, three developed preretinal hemorrhage around the ridge after the first treatment, resulting in fibrotic macular dragging. A half dose of IVB may be more effective than a minimal dose with partial TRSL for ROP. Preretinal hemorrhage may be a harbinger of poor prognosis.

关键词： bevacizumab laser photocoagulation retinopathy of prematurity

Special ideals in partial abelian monoids

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Applied Mathematics(A Journal of Chinese Universities) 2010年第1期25卷 112-116页

作者： yu Zhi-jian cho Min-hyung WU Jun-de Department of Mathematics Taizhou University Linhai 317000 China Department of Applied Mathematics Kumoh National Institute of Technology Kyungbuk 730-701Korea Department of Mathematics Zhejiang University Hangzhou 310027 China

Under some conditions, the special congruences of partial abelian monoid are those induced by the special ideals, and a class of special ideals of partial abelian monoid has some upper and lower bound properties.

关键词： Quantum logic partial abelian monoid ideal.

Exploring catalytic behaviors of CoS_(2)-ReS_(2) heterojunction by interfacial engineering

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Journal of Energy Chemistry 2023年第10期85卷 11-18,I0002页

作者： Jianmin yu Yongteng Qian Sohyeon Seo Yang Liu Huong T.D.Bui Ngoc Quang Tran Jinsun Lee Ashwani Kumar Hongdan Wang Yongguang Luo Xiaodong Shao yunhee cho Xinghui Liu Min Gyu Kim Hyoyoung Lee Department of Chemistry Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea Center for Integrated Nanostructure Physics(CINAP) Institute of Basic Science(IBS)Suwon 16419Republic of Korea College of Pharmacy Jinhua PolytechnicJinhua 321007ZhejiangChina Beamline Research Division Pohang Accelerator Laboratory(PAL)Pohang University of Science and TechnologyPohang 37673Republic of Korea Department of Biophysics Sungkyunkwan University2066 SeoburoJangan-guSuwon 16419Republic of Korea Creative Research Institute Sungkyunkwan University2066 SeoburoJangan-guSuwon 16419Republic of Korea

Herein, a stable and efficient CoS_(2)-ReS_(2) electrocatalyst is successfully constructed by using the different molar ratios of CoS_(2) on ReS_(2). The size and morphology of the catalysts are significantly changed after the CoS_(2) is grown on ReS_(2), providing regulation of the catalytic activity of ReS_(2). Particularly, the optimized CoS_(2)-ReS_(2) shows superior electrocatalytic properties with a low voltage of 1.48 V at 20 mA cm^(-2) for overall water splitting in 1.0 M KOH, which is smaller than the noble metal-based catalysts(1.77 V at 20 mA cm^(-2)). The XPS, XAS, and theoretical data confirm that the interfacial regulation of ReS_(2) by CoS_(2) can provide rich edge catalytic sites, which greatly optimizes the catalytic kinetics and drop the energy barrier for oxygen/hydrogen evolution reactions. Our results demonstrated that interfacial engineering is an efficient route for fabricating high-performance water splitting electrocatalysts.

关键词： CoS_(2) ReS_(2) Interfacial engineering Catalytic kinetics Water splitting

Mechanical properties of graphene oxide?silk fibroin bionanofilms via nanoindentation experiments and finite element analysis

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Friction 2022年第2期10卷 282-295页

作者： Hyeonho cho Joonho LEE Hyundo HWANG Woonbong HWANG Jin-Gyun KIM Sunghan KIM School of Mechanical Engineering Chung-Ang UniversitySeoul 06974Republic of Korea Department of Mechanical Engineering(Integrated Engineering) Kyung Hee UniversityGyeonggi 17104Republic of Korea Department of Mechanical Engineering POSTECHPohang 37673Republic of Korea Department of Robotics&Mechatronics.Korea Institute of Machinery&Materials Daejeon 34103Republic of Korea

Understanding the mechanical properties of bionanofilms is important in terms of identifying their *** primary focus of this study is to examine the effect of water vapor annealed silk fibroin on the indentation modulus and hardness of graphene oxide-silk fibroin(GO-SF)bionanofilms through nanoindentation experiments and finite element analysis(FEA).The GO-SF bionanofilms were fabricated using the layer-by-layer *** water vapor annealing process was employed to enhance the interfacial properties between the GO and SF layers,and the mechanical properties of the GO-SF bionanofilms were found to be affected by this *** employing water vapor annealing,the indentation modulus and hardness of the GO-SF bionanofilms can be ***,the FEA models of the GO-SF bionanofilms were developed to simulate the details of the mechanical behaviors of the GO-SF *** difference in the stress and strain distribution inside the GO-SF bionanofilms before and after annealing was *** addition,the load-displacement curves that were obtained by the developed FEA model conformed well with the results from the nanoindentation *** summary,this study presents the mechanism of improving the indentation modulus and hardness of the GO-SF bionanofilms through the water vapor annealing process,which is established with the FEA simulation models.

关键词： graphene oxide silk fibroin layer-by-layer(LbL) nanoindentation finite element analysis(FEA)

Preclinical Long-term Magnetic Resonance Imaging Study of Silymarin Liver-protective Effects

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Journal of Clinical and Translational Hepatology 2022年第6期10卷 1167-1175页

作者： Yeon Ji Chae Hwon Heo Chul-Woong Woo Sang-Tae Kim Jae-Im Kwon Monica Young choi yu Sub Sung kyung Won Kim Jeong Kon Kim Yoonseok choi Dong-Cheol Woo Department of Convergence Medicine Asan Medical CenterUniversity of Ulsan College of MedicineSeoulRepublic of Korea Convergence Medicine Research Center Asan Institute for Life SciencesAsan Medical CenterSeoulRepublic of Korea Clinical Research Center Asan Medical CenterSeoulRepublic of Korea Department of Radiology Asan Medical CenterUniversity of Ulsan College of MedicineSeoulRepublic of Korea Medical Research Institute Gangneung Asan HospitalGangneung-siGangwon-doRepublic of Korea

Background and Aims:Efficacy evaluations with preclini-cal magnetic resonance imaging(MRI)are uncommon,but MRI in the preclinical phase of drug development provides information that is useful for longitudinal *** study aim was to monitor the protective effectiveness of silymarin with multiparameter MRI and biomarkers in a thioacetamide(TAA)-induced model of liver injury in *** analysis was conducted to assess compare the monitoring of liver function by MRI and ***-ods:TAA was injected three times a week for 8 weeks to generate a disease model(TAA group).In the TAA and sily-marin-treated(TAA-SY)groups,silymarin was administered three times weekly from week *** images were acquired at 0,2,4,6,and 8 weeks in the control,TAA,and TAA-SY ***:The area under the curve to maximum time(AUCtmax)and T_(2)*values of the TAA group decreased over the study period,but the serological markers of liver abnormality increased significantly more than those in the control *** the TAA-SY group,MRI and serological biomarkers indicated attenuation of liver function as in the TAA ***,pattern changes were observed from week 6 to comparable levels in the control group with si-lymarin *** correlations between either AUCtmax or T_(2)*values and the serological biomarkers were ***:Silymarin had hepatoprotective effects on TAA-induced liver injury and demonstrated the usefulness of multiparametric MRI to evaluate efficacy in preclinical studies of liver drug development.

关键词： Liver fibrosis Magnetic resonance imaging Silymarin T1-weight-ed dynamic contrast-enhanced T_(2)*

The geometrical properties of parity and time reversal operators in two dimensional spaces

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Applied Mathematics(A Journal of Chinese Universities) 2019年第2期34卷 173-183页

作者： HUANG Min-yi YANG yu WU Jun-de cho Min-Hyung School of Mathematical Science Zhejiang UniversityHangzhou 310027People’s Republic of China Department of Mathematics National University of SingaporeSingapore 119076Republic of Singapore Department of Applied Mathematics Kumoh National Institute of TechnologyKyungbuk39177Korea

The parity operator P and time reversal operator T are two important operators in the quantum theory, in particular, in the PT -symmetric quantum theory. By using the concrete forms of P and T , we discuss their geometrical properties in two dimensional spaces. It is showed that if T is given, then all P links with the quadric surfaces;if P is given, then all T links with the quadric curves. Moreover, we give out the generalized unbroken PT -symmetric condition of an operator. The unbroken PT -symmetry of a Hermitian operator is also showed in this way.

关键词： PT -symmetry geometrical property unbroken condition

Prediction of effluent concentration in a wastewater treatment plant using machine learning models

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Journal of Environmental Sciences 2015年第6期27卷 90-101页

作者： Hong Guo Kwanho Jeong Jiyeon Lim Jeongwon Jo Young Mo Kim Jong-pyo Park Joon Ha Kim kyung Hwa cho School of Environmental Science and Engineering Gwangju Institute of Science and Technology (GIST) School of Urban and Environmental Engineering Ulsan National Institute of Science and Technology HECOREA. INC

Of growing amount of food waste, the integrated food waste and waste water treatment was regarded as one of the efficient modeling method. However, the load of food waste to the conventional waste treatment process might lead to the high concentration of total nitrogen（T-N） impact on the effluent water quality. The objective of this study is to establish two machine learning models-artificial neural networks（ANNs） and support vector machines（SVMs）, in order to predict 1-day interval T-N concentration of effluent from a wastewater treatment plant in Ulsan, Korea. Daily water quality data and meteorological data were used and the performance of both models was evaluated in terms of the coefficient of determination（R^2）, Nash-Sutcliff efficiency（NSE）, relative efficiency criteria（d rel）. Additionally, Latin-Hypercube one-factor-at-a-time（LH-OAT） and a pattern search algorithm were applied to sensitivity analysis and model parameter optimization, respectively. Results showed that both models could be effectively applied to the 1-day interval prediction of T-N concentration of effluent. SVM model showed a higher prediction accuracy in the training stage and similar result in the validation ***, the sensitivity analysis demonstrated that the ANN model was a superior model for 1-day interval T-N concentration prediction in terms of the cause-and-effect relationship between T-N concentration and modeling input values to integrated food waste and waste water treatment. This study suggested the efficient and robust nonlinear time-series modeling method for an early prediction of the water quality of integrated food waste and waste water treatment process.

关键词： Artificial neural network Support vector machine Effluent concentration Prediction accuracy Sensitivity analysis

Evaluation of the relationship between two different methods for enumeration fecal indicator bacteria: Colony-forming unit and most probable number

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Journal of Environmental Sciences 2010年第6期22卷 846-850页

作者： kyung Hwa cho Dukki Han Yongeun Park Seung Won Lee Sung Min Cha Joo-Hyon Kang Joon Ha Kim Department of Environmental Science and Engineering Gwangju Institute of Science and Technology Deparment of Civil and Environmental Engineering Dongguk University-Seoul Sustainable Water Resource Technology Center Gwangju Institute of Science and Technology

Most probable number （MPN） and colony-forming unit （CFU） estimates of fecal indicator bacteria （FIB） concentration are common measures of water quality in aquatic environments. Thus, FIB intensively monitored in Yeongsan Watershed in an attempt to compare two different methods and to develop a statistical model to convert from CFU to MPN estimates or vice versa. As a result, the significant difference was found in the MPN and CFU estimates. The enumerated Escherichia coli concentrations in MPN are greater than those in CFU, except for the measurement in winter. Especially in fall, E. coli concentrations in MPN are one order of magnitude greater than that in CFU. Contrarily, enterococci bacteria in MPN are lower than those in CFU. However, in general, a strongly positive relationship are found between MPN and CFU estimates. Therefore, the statistical models were developed, and showed the reasonable converting FIB concentrations from CFU estimates to MPN estimates. We expect this study will provide preliminary information towards future research on whether different analysis methods may result in different water quality standard violation frequencies for the same water sample.

关键词： most probable number colony-forming unit fecal indicator bacteria Escherichia coli enterococci

Rapid hemostasis of the residual inguinal access sites during endovascular procedures:A case report

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World Journal of Clinical Cases 2022年第34期10卷 12684-12689页

作者： Hyangkyoung Kim Kwangjin Lee Sungsin cho Jin Hyun Joh Department of Vascular Surgery Kyung Hee University Hospital at GangdongSeoul 05278South Korea Department of Surgery Kyung Hee University Hospital at GangdongSeoul 05278South Korea

BACKGROUND In endovascular procedures including total percutaneous endovascular aneurysm repair(pEVAR),percutaneous access through the common femoral artery is most commonly ***-site bleeding is a major concern in percutaneous ***,we present a case of successful control of continuous oozing using a vascular closure device(VCD)and the application of Surgicel(Johnson&Johnson,United States)over the access *** SUMMARY An 82-year-old man presented with an unruptured abdominal aortic aneurysm measuring 83 mm×75 *** patient had a medical history of atrial fibrillation and was receiving rivaroxaban(15 mg/d).Routine pEVAR was performed using the preclose technique with ProGlide(Abbott,Santa Clara,CA,United States).Significant amount of bleeding was observed at the end of the procedure after the deployment of the closure device at the access site.A sheet of Surgicel was applied to the suture thread using a surgical *** was applied to the surface of the artery along the access tract using a pusher,and hemostasis was immediately *** This simple technique is an excellent adjunct to control residual bleeding from the access site following VCD use.

关键词： Endovascular procedures Punctures Hemostasis Hemostatic techniques Femoral artery Case report