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资源支持、组织能力与价值创造:社区互助养老服务可持续生产的驱动路径

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海南大学学报（人文社会科学版） 2025年第1期43卷 107-118页

作者：翟绍果韩煜西北大学公共管理学院陕西西安710127

社区互助养老服务何以可持续生产,基于“环境-组织-价值”分析框架,以我国37个社区互助养老典型案例为样本,运用模糊集定性比较分析方法;(fsQCA)探究社区互助养老服务可持续生产的组态驱动路径。研究表明:;(1)外部支持、社区资源、主体... 详细信息

社区互助养老服务何以可持续生产,基于“环境-组织-价值”分析框架,以我国37个社区互助养老典型案例为样本,运用模糊集定性比较分析方法;(fsQCA)探究社区互助养老服务可持续生产的组态驱动路径。研究表明:;(1)外部支持、社区资源、主体协同、制度化水平、技术赋能与价值创造通过组态效应影响社区互助养老服务的可持续生产;(2)外部支持与社区资源、制度化水平与技术赋能具有潜在替代性,社区资源和价值创造是组态形成的关键因素;(3)党政统合型、社区自组织型、技术嵌入型和协同驱动型是驱动社区互助养老服务可持续生产的4种优化路径。实现社区互助养老服务高水平的可持续生产应坚持系统联动思维,释放多元组态的复合驱动效应,重视社区资源和价值创造的关键作用,选择适宜不同地区发展基础的互助养老模式。

关键词：社区互助养老可持续生产驱动路径

Cerebral fat embolism following autologous fat injection in facial reconstruction:A case report

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World Journal of Clinical Cases 2025年第2期13卷 50-58页

作者： Xiu-Ying Chen Fa Shen Chang Cheng yu-han Wang Wen-Chao Cheng De-Zhi yuan Wen Huang Department of Neurology Chongqing Emergency Medical CenterChongqing University Central HospitalChongqing 400000China Department of Neurology Xinqiao HospitalThe Army Medical University(Third Military Medical University)Chongqing 400000China

BACKGROUND Autologous fat injection in facial reconstruction is a common cosmetic *** cerebral fat embolism(CFE)as a complication is rare,it carries serious health *** SUMMARY We present a case of a 29-year-old female patient who developed acute CFE following facial fat filling *** the surgery,the patient experienced symptoms including headache,nausea,vomiting,and difficulty breathing,which was followed by neurological symptoms such as slurred speech and left-sided *** physical examination and auxiliary investigations,including blood tests,head and neck computed tomography angiography,and cranial magnetic resonance diffusion-weighted imaging,were performed upon *** clinical diagnosis was acute cerebral embolism following facial fat filling *** included measures to improve cerebral circulation,dehydration for intracranial pressure reduction,nutritional support,and rehabilitation therapy for left limb *** patient showed a significant improvement in symptoms after 2 weeks of *** recovered left limb muscle strength to grade 5,had clear speech,and experienced complete relief of *** Our case highlights the potential occurrence of severe complications in patients undergoing fat injection in facial *** prevent these complications,plastic surgeons should enhance their professional knowledge and skills.

关键词： Cerebral fat embolism Mechanical thrombectomy Thrombolysis Steroid therapy Symptomatic treatment Case report

环状RNA CHACR调控压力超负荷诱导心肌肥大和氧化应激损伤

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中国组织工程研究 2025年第25期29卷 5362-5373页

作者：王霜韩瑜袁敏曹济民孙腾山西医科大学细胞生理学教育部重点实验室山西省细胞生理学重点实验室山西医科大学基础医学院生理学系山西省太原市030001

背景:病理性心肌肥大是多种心脏疾病的危险促进因素,但其发病机制仍未阐明。环状RNA与心肌肥大密切相关,然而环状RNA CHACR在心肌肥大中的作用及调控机制尚未见报道。目的:探究环状RNA CHACR在压力超负荷诱导心肌肥大中的作用及机制。方... 详细信息

背景:病理性心肌肥大是多种心脏疾病的危险促进因素,但其发病机制仍未阐明。环状RNA与心肌肥大密切相关,然而环状RNA CHACR在心肌肥大中的作用及调控机制尚未见报道。目的:探究环状RNA CHACR在压力超负荷诱导心肌肥大中的作用及机制。方法:①心脏原位注射环状RNA CHACR过表达慢病毒1周后进行横向主动脉缩窄手术诱导小鼠心肌肥大。术后8周,计算心脏质量/胫骨长比值和肺质量/胫骨长比值,测量心肌细胞表面积,检测肥大标志基因表达水平和心肌纤维化程度,评估心功能。②H9c2心肌细胞给予环状RNA CHACR过表达慢病毒处理72 h,然后加入1μmol/L血管紧张素Ⅱ处理24 h诱导心肌细胞肥大。通过检测心肌细胞表面积、肥大标志基因表达水平、蛋白质/DNA比值评估细胞肥大情况,通过检测活性氧水平和线粒体膜电位评估氧化应激损伤情况。结果与结论:①在体内和体外心肌肥大模型中,环状RNA CHACR的表达水平均显著降低(P<0.01);②过表达环状RNA CHACR显著抑制了横向主动脉缩窄手术诱导的小鼠心肌肥大表型,主要表现为心脏体积减小、心脏质量/胫骨长比值显著降低(P<0.05),肺质量/胫骨长比值显著降低(P<0.05),心肌细胞表面积显著减小(P<0.05),以及心肌肥大相关标志基因心房利钠肽(P<0.05)、脑钠肽(P<0.05)表达水平降低;③过表达环状RNA CHACR显著抑制了横向主动脉缩窄手术诱导的小鼠心脏纤维化,表现为纤维化面积减小(P<0.01)和纤维化标志基因Acta1的表达水平降低(P<0.05);④过表达环状RNA CHACR显著改善了小鼠心功能,主要表现为射血分数(P<0.05)和短轴缩短率(P<0.01)显著升高;(5)过表达环状RNA CHACR显著抑制了血管紧张素Ⅱ诱导的心肌细胞肥大,主要表现为心肌细胞表面积显著减小(P<0.05),心房利钠肽(P<0.05)和脑钠肽(P<0.05)表达水平显著下调,以及蛋白质/DNA比值显著减小(P<0.05);(6)过表达环状RNA CHACR显著抑制了血管紧张素Ⅱ诱导的活性氧水平升高(P<0.001)和线粒体膜电位降低(P<0.05)。结果表明,环状RNA CHACR在体内和体外心肌肥大模型中表达水平显著降低,过表达环状RNA CHACR显著抑制心肌肥大,减轻心肌纤维化,改善心功能,并且显著减轻了血管紧张素Ⅱ诱导的心肌细胞氧化应激损伤。

关键词：心肌肥大环状RNA CHACR 血管紧张素Ⅱ 横向主动脉缩窄手术氧化应激损伤

Optimizing product manufacturability in 3D printing

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Frontiers of Computer Science 2017年第2期11卷 347-357页

作者： yu han Guozhu JIA School of Economics and Management Beihang University Beijing 100191 China

3D printing has become a promising technique for industry production. This paper presents a research on the manufacturability optimization of discrete products un- der the influence of 3D printing technology. For this, we first model the problem using a tree structure, and then formulate it as a linear integer programming, where the total production time is to be minimized with the production cost constraint. To solve the problem, a differential evolution （DE） algorithm is developed, which automatically determines whether tra- ditionai manufacturing methods or 3D printing technology should be used for each part of the production. The algorithm is further quantitatively evaluated on a synthetic dataset, com- pared with the exhaustive search and alternating optimization solutions. Simulation results show that the proposed algo- rithm can well combine the traditional manufacturing meth- ods and 3D printing technology in production, which is help- ful to attain optimized product design and process planning concerning manufacture time. Therefore, it is beneficial to provide reference of the widely application and further in- dustrialization of the 3D printing technology.

关键词： 3D printing manufacturability optimization,discrete products differential evolution algorithm

Mechanistic insight into the synergy between nickel single atoms and nanoparticles on N-doped carbon for electroreduction of CO2

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Journal of Energy Chemistry 2025年第01期 327-336页

作者： Mingdong Sun Wenwen Guan Cailing Chen Chao Wu Xiaoling Liu Biao Meng Tao Chen yu han Jun Wang Shibo Xi yu Zhou State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical Engineering Nanjing Tech University Advanced Membranes and Porous Materials Center Physical Sciences and Engineering Division King Abdullah University of Science and Technology Institute of Sustainability for Chemicals Energy and Environment A*STAR (Agency for Science Technology and Research) College of Materials Science and Engineering Sichuan University

The synergy of single atoms （SAs） and nanoparticles （NPs） has demonstrated great potential in promoting the electrocatalytic carbon dioxide reduction reaction （CO2RR）;however,the rationalization of the SAs/NPs proportion remains one challenge for the catalyst ***,a Ni2+-loaded porous poly（ionic liquids）(PIL) precursor synthesized through the free radical self-polymerization of the ionic liquid monomer,1-allyl-3-vinylimidazolium chloride,was pyrolyzed to prepare the Ni,N co-doped carbon materials,in which the proportion of Ni SAs and NPs could be facilely modulated by controlling the annealing *** catalyst Ni-NC-1000 with a moderate proportion of Ni SAs and NPs exhibited high efficiency in the electrocatalytic conversion of CO2into *** Ni K-edge X-ray absorption near-edge structure （XANES） spectra and theoretical calculations were conducted to gain insight into the synergy of Ni SAs and *** charge transfer from Ni NPs to the surrounding carbon layer and then to the Ni SAs resulted in the electron-enriched Ni SAs active *** the electroreduction of CO2,the coexistence of Ni SAs and NPs strengthened the CO2activation and the affinity towards the key intermediate of*COOH,lowering the free energy for the potential-determining*CO2→*COOH step,and therefore promoted the catalysis efficiency.

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Numerical simulation of viscous flows with adaptively refined Cartesian grid

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航空动力学报 2014年第2期29卷 467-474页

作者： han yu-qi GAO Ge National Key Laboratory of Science and Technology on Aero-Engine Aero-thermodynamics School of Energy and Power EngineeringBeijing University of Aeronautics and Astronautics

Quadtree-based Cartesian grid was automatically generated from specified *** refinements were performed according to geometric parameters and solution of flow *** altered CCST(curvature corrected symmetry technique)approach was proposed to apply solid wall boundary conditions. Driven flows in a square cavity and flows around NACA0012airfoil were simulated and compared with the result of published structured grid and stretched Cartesian *** results show that solid wall boundary condition are accurately applied by current altered CCST approach,while incompressible/compressible subsonic, transonic and supersonic viscous flows are adequately simulated with adaptively refined Cartesian grid.

关键词： adaptively refined Cartesian grid viscous flow CCST(curvature corrected symmetry technique) boundary condition

Interfacial defective Ti^(3+) on Ti/TiO_(2) as visible-light responsive sites with promoted charge transfer and photocatalytic performance

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Journal of Materials Science & Technology 2022年第11期106卷 139-146页

作者： Yangfan Zhang Yao Li han yu Kai yu Hongbing yu College of Environmental Science and Engineering Nankai UniversityTianjin 300350China Department of Water Resources Engineering Lund University22100 LundSweden School of Economics and Management Tiangong UniversityTianjin 300350China

Defect sites on oxide semiconductors play a crucial role in promoting photocatalytiperformance and mod-ulating the bandgap structure of ***,the role of interfacial coordinatively unsatu-rated defect sites between metal and oxide in photocatalysis is still under ***,we designed an experiment to probe the role of interfacial coordinatively unsaturated defect *** this work,a se-ries of Ti/TiO_(2) photocatalysts with varying concentrations of interfacial Ti^(3+)sites were prepared through an epitaxial growth method under hydrothermal *** experimental and computational investigations,the roles of interfacial defect sites were discussed in *** the one hand,the inter-facial coordinatively unsaturated Ti^(3+)sites could act as visible-light-responsive sites in photocatalytic reactions due to the overlap and hybridization of multiple electronic *** the other hand,the Ti/TiO_(2) interface exhibited a certain degree of metallic character near the Fermi level because of the par-tial delocalization and redistribution of electrons,facilitating the charge migration and separation across the metal-oxide ***,the obtained Ti/TiO_(2) catalysts showed notably enhanced charge transfer efficiency and visible light photocatalytic activity compared to their pristine *** work may provide a new perspective to interfacial defect engineering in classic metal/oxide heterojunc-tion photocatalysts and figure a more precise direction to synthesize higher effective photocatalysts for environmental governance.

关键词： Interfacial defect engineering Ti/TiO_(2)interface Coordinatively unsaturated site Visible-light photocatalysis DFT calculation

Efficient capture of iodine and methyl iodide using all-silica EMM-17 zeolite

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Nano Research 2023年第5期16卷 6308-6315页

作者： Tingting Pan Xinglong Dong yu han Advanced Membranes and Porous Materials(AMPM)Center Physical Sciences and Engineering DivisionKing Abdullah University of Science and Technology(KAUST)Thuwal 23955-6900Saudi Arabia

Hydrophobic zeolites have been identified as suitable adsorbents for capturing radioactive iodine species from nuclear-powerplant off-gas because of their high stability and strong water ***,only the most common zeolites have been investigated for the capture of molecular iodine to ***,we demonstrate that the composition and pore structure of zeolites considerably affect their iodine adsorption performance.A novel all-silica ExxonMobil material-17(EMM-17)zeolite having a unique three-dimensional 10(12)×10(12)×11-ring channel system exhibits a high adsorption capacity for iodine and methyl iodide in the presence of ***-17 outperforms previously reported zeolites in terms of gravimetric and volumetric adsorption capacity in dynamic adsorption *** excellent iodine/methyl iodide capture properties are attributed to the combination of optimal pore size,high pore volume,strong hydrophobicity,suitable particle *** study provides useful insights for designing efficient adsorbents for iodine capture.

关键词： ExxonMobil material-17(EMM-17)zeolite iodine capture methyl iodide adsorption

Three-dimensional cytoplasmic calcium propagation with boundaries

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Communications in Theoretical Physics 2021年第1期73卷 87-98页

作者： han-yu Jiang Jun He Department of Physics and Institute of Theoretical Physics Nanjing Normal UniversityNanjing210097China Sino-U.S.Center for Grazingland Ecosystem Sustainability/Pratacultural Engineering Laboratory of Gansu Province/Key Laboratory of Grassland Ecosystem Ministry of Education/College of Pratacultural ScienceGansu Agricultural UniversityLanzhou730070China

Ca^(2+)plays an important role in cell signal *** intracellular propagation is the most basic process of Ca^(2+)signaling,such as calcium wave and double messenger *** this work,with both numerical simulation and mean field ansatz,the three-dimensional probability distribution of Ca^(2+),which is read out by phosphorylation,is studied in two scenarios with *** coverage of distribution of Ca^(2+)is found at an order of magnitude ofμm,which is consistent with experimental observed calcium spike and *** results suggest that the double messenger system may occur in the ER-PM junction to acquire great *** buffer effect of kinase is also discussed by calculating the average position of phosphorylations and free Ca^(2+).The results are helpful to understand the mechanism of Ca^(2+)signaling.

关键词： Ca^(2+)signaling diffusion Gillespie algorithm mean field ansatz