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Mobility and dynamic erosion process of granular flow:insights from numerical investigation using material point method

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Journal of Mountain Science 2024年第8期21卷 2713-2738页

作者： yu Fangwei SU Lijun LI Xinpo ZHAO yu Institute of Mountain Hazards and Environment Chinese Academy of SciencesChengdu 610299China University of Chinese Academy of Sciences Beijing 100049China China-Pakistan Joint Research Center on Earth Sciences Islamabad 45320Pakistan Center for Excellence in Tibetan Plateau Earth Sciences Chinese Academy of SciencesBeijing 100101China College of Civil Engineering and Architecture Zhejiang UniversityHangzhou 310058China MOE Key Laboratory of Soft Soil and geoenvironmental Engineering Zhejiang UniversityHangzhou 310058China

In order to understand the dynamics of granular flow on an erodible base soil,in this paper,a series of material point method-based granular column collapse tests were conducted to investigate numerically the mobility and dynamic erosion process of granular flow subjected to the complex settings,i.e.,the aspect ratio,granular mass,friction and dilatancy resistance,gravity and presence of water.A set of power scaling laws were proposed to describe the final deposit characteristics of granular flow by the relations of the normalized run-out distance and the normalized final height of granular flow against the aspect ratio,being greatly affected by the complex geological settings,e.g.,granular mass,the friction and dilatancy resistance of granular soil,and presence of water in granular *** index of the coefficient of friction of granular soil was defined as a ratio of the target coefficient of friction over the initial coefficient of friction to quantify the scaling extent of friction change(i.e.,friction strengthening or weakening).There is a characteristic aspect ratio of granular column corresponding to the maximum mobility of granular flow with the minimum index of the apparent coefficient of *** index of the repose coefficient of friction of granular flow decreased gradually with the increase in aspect ratio because higher potential energy of granular column at a larger aspect ratio causes a larger kinetic energy of granular soil to weaken the friction of granular soil as a kind of velocity-related friction *** increase in granular mass reduces gradually the indexes of the apparent and repose coefficients of friction of granular soil to enhance the mobility of granular *** mobility of granular flow increases gradually with the decrease in friction angle or increase in dilatancy angle of granular ***,the increase of gravity accelerates granular flow but showing the same final deposit profile without any dependence on ***

关键词： Column collapse granular flow granular soil Material point method Mobility Numerical tests

Current status and trends in small nucleic acid drug development:Leading the future

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Acta Pharmaceutica Sinica B 2024年第9期14卷 3802-3817页

作者： yuxi Miao Chen Fu Zhaojin yu Lifeng yu yu Tang Minjie Wei Department of Pharmacology School of PharmacyChina Medical UniversityShenyang 110122China Liaoning Key Laboratory of Molecular Targeted Anti-Tumor Drug Development and Evaluation China Medical UniversityShenyang 110122China Liaoning Medical Diagnosis and Treatment Center Shenyang 110000China Department of Oncology Cancer Hospital of China Medical UniversityLiaoning Cancer Hospital and InstituteShenyang 110042China

Small nucleic acid drugs,composed of nucleotides,represent a novel class of pharmaceuticals that differ significantly from conventional small molecule and antibody-based *** agents function by selectively targeting specific genes or their corresponding messenger RNAs(mRNAs),further modulating gene expression and regulating translation-related *** examples within this category include antisense oligonucleotides(ASO),small interfering RNAs(siRNAs),micro-RNAs(miRNAs),and *** emergence of small nucleic acid drugs as a focal point in contemporary biopharmaceutical research is attributed to their remarkable specificity,facile design,abbreviated development cycles,expansive target spectrum,and prolonged *** challenges such as poor stability,immunogenicity,and permeability issues have been addressed through the integration of chemical modifications and the development of drug delivery *** review provides an overview of the current status and prospective trends in small nucleic acid drug *** with a historical context,we introduce the primary classifications and mechanisms of small nucleic acid ***,we delve into the advantages of the *** and Drug Administration(FDA)approved drugs and mainly discuss the challenges encountered during their *** from researching chemical modification and delivery system that efficiently deliver and enrich small nucleic acid drugs to target tissues,promoting endosomal escape is a critical scientific question and important research direction in siRNA drug *** directions in this field will prioritize addressing these challenges to facilitate the clinical transformation of small nucleic acid drugs.

关键词： Small nucleic acid drugs Oligonucleotide drugs siRNA ASO miRNA Aptamer RNAi Drug development

Single-atom catalysts for neutral zinc-air batteries

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Science China Materials 2024年第5期67卷 1674-1675页

作者： Jiaxu Zhang Minghao yu Faculty of Chemistry and Food Chemistry&Center for Advancing Electronics Dresden(CfAED) Technische Universität DresdenDresden01062Germany

The escalating global energy demand underscores the urgency of developing sustainable battery ***-air batteries(ZABs)have emerged as promising candidates due to their costeffectiveness,safety,and high energy density[1-4].Conventional ZABs typically rely on a four-electron(4e-)oxygen reduction reaction(ORR)in strongly alkaline electrolytes.

关键词： battery neutral typically

Control of Virtual Synchronous generator for Frequency Regulation Using a Coordinated Self-adaptive Method

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CSEE Journal of Power and Energy Systems 2024年第1期10卷 175-184页

作者： Hongwei Fang Zhiwei yu School of Electrical and Information Engineering and Key Laboratory of Tianjin Electric Power System Simulation and Control Tianjin UniversityTianjin 300072China

Power inverter adopting virtual synchronous generator(VSg)control can provide inertia support for distributed generation ***,it cannot take into account the dynamic regulation characteristics of ***,when the system encounters a sudden change in load or disturbance,the dynamic process of frequency regulation will be greatly *** view of this issue,an improved VSg control strategy based on a coordinated self-adaptive(CSA)method is *** time domain analysis method is used to study the influences of virtual inertia and damping parameter perturbation on the system steady and dynamic ***,in order to make the control strategy suitable for large load changes and suppress frequency variations beyond the limit,the secondary frequency modulation is introduced into the control *** the coordinated adaptive control of virtual inertia,virtual damping and frequency modulation,the dynamic performance of vSg frequency regulation can be obviously *** and experiment results have verified the effectiveness of the proposed CSA control strategy.

关键词： Coordinated self-adaptive method frequency regulation time domain analysis virtual synchronous generator

Immersive visualization of 3D subsurface ground model developed from sparse boreholes using virtual reality(VR)

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Underground Space 2024年第4期17卷 188-206页

作者： Borui Lyu yu Wang Department of Architecture and Civil Engineering City University of Hong KongKowloon 999077Hong KongChina

Analytics and visualization of multi-dimensional and complex geo-data,such as three-dimensional(3D)subsurface ground models,is critical for development of underground space and design and construction of underground structures(e.g.,tunnels,dams,and slopes)in engineering *** complicated 3D subsurface ground models now can be developed from site investigation data(e.g.,boreholes)which is often sparse in practice,it remains a great challenge to visualize a 3D subsurface ground model with sophisticated stratigraphic variations by conventional two-dimensional(2D)geological *** reality(VR)technology,which has an attractive capability of constructing a virtual environment that links to the physical world,has been rapidly developed and applied to visualization in various disciplines *** on the rapid development of VR,this study proposes a framework for immersive visualization of 3D subsurface ground models in geo-applications using VR *** 3D subsurface model is first developed from limited borehole data in a data-driven ***,a VR system is developed using related software and hardware devices currently available in the markets for immersive visualization and interaction with the developed 3D subsurface ground *** results demonstrate that VR visualization of the 3D subsurface ground model in an immersive environment has great potential in revolutionizing the geo-practices from 2D cross-sections to a 3D immersive virtual environment in digital era,particularly for the emerging digital twins.

关键词： Immersive visualization 3D subsurface model Virtual reality Virtual environment Interaction

A Strong,Tough,and Self-Healing Strengthening Thioctic Acid-based Elastomer for Highly Reliable Flexible Strain Sensor

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Chinese Journal of Polymer Science 2024年第10期42卷 1610-1618,I0016页

作者： Xin-yu Chen yu-Bing Fu Xue-Ling Yan Lan Liu School of Materials Science and Engineering Key Lab of Guangdong Province for High Property and Functional Polymer MaterialsSouth China University of TechnologyGuangzhou510641China

Elastomers with high strength and toughness,excellent self-healing properties,and biocompatibility have broad application prospects in wearable electronics and other fields,but preparing it remains a *** this work,we propose a highly adaptable strategy by introducing the small molecule crosslinking agent of triethanolamine(TEA)to the poly(thioctic acid)(PTA)chains and preparing the PAx Ey elastomers using a simple synthesis *** strategy stabilizes the PTA chains by constructing multiple non-covalent cross-linked dynamic networks,endowing materials with excellent strength and toughness(tensile strength of 288 kPa,toughness of 278.2 kJ/m3),admirable self-healing properties(self-healing efficiency of 121.6%within 7 h at 70℃),and good *** PAx Ey elastomers can also be combined with MWNTs to become flexible strain sensors,which can be used to monitor human joint movements with high sensitivity,repeatable responses,and stability.

关键词： Thioctic acid Ion clusters Multiple dynamic networks Self-healing strengthening Flexible strain sensor

Effect of Cr_(2)O_(3) on properties of CaO-SiO_(2)-Fe_(t)O-MgO system and dissolution behavior of lime

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Journal of Iron and Steel Research International 2024年第4期31卷 870-881页

作者： Shan-nan Li Jian-li Li yue yu Hang-yu Zhu The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina Hubei Provincial Key Laboratory for New Processes of Ironmaking and Steelmaking Wuhan University of Science and TechnologyWuhan 430081HubeiChina Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081HubeiChina

The productivity of the chrome-containing semi-steel converter smelting process is directly affected by the slag-forming speed during the converter preliminary *** effects of Cr_(2)O_(3) content on the physicochemical properties of the CaO-SiO_(2)-Fe_(t)O-MgO system,such as melting temperature,solidification behavior,mineral composition,and lime dissolution rate,were *** results showed that the slag was an amorphous phase at 1500℃.When Cr_(2)O_(3) was added,Ca(Fe,Mg)Si_(2)O_(6) and spinel were formed in the *** the increase in Cr_(2)O_(3) content,the amount of spinel precipitation increased,and the dendritic FegO_(4) crystal gradually changed into the granular(Fe,Mg)(Fe,Cr)2O_(4) *** the Cr_(2)O_(3) content increased from O to 2.91 wt.%,the melting temperature of the slag rose,and the melting range of the slag expanded slightly,but the lime dissolution rate did not *** the Cr_(2)O_(3) content further increased to 9.09 wt.%,the melting temperature continued to rise,the melting range rapidly expanded,and the lime dissolution rate decreased.

关键词： Cr_(2)O_(3) Vanadium-titanium magnetite Converter Slag Lime dissolution

Characteristic Analysis of Power Oscillations Caused by Disharmony Among Voltage-source-controlled Units in Three-terminal Local Power grid

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Journal of Modern Power Systems and Clean Energy 2024年第4期12卷 1295-1308页

作者： Qiyi yu Yi Tang School of Electrical Engineering Southeast UniversityNanjing 210018China

Previous studies have demonstrated that disharmo-ny among voltage-source-controlled units(VSCUs)may occur on an alternating current(AC)transmission or distribution line under steady-state operating conditions(SSOCs)or quasi-static operating conditions(QSSOCs).As the studies on frequency dis-harmony have been expanded to multiple disharmonized vS-CUs in the local power grid,its adverse effects on AC lines and equivalent load(EL)at the bus without active voltage control ability(non-active bus)need to be investigated ***-ering the locality of disharmony and common topological con-nections among VSCUs,this paper adopts a Y-type three-termi-nal local power grid(LPg)as the research *** dishar-mony among the three VSCUs is ***,for the load at non-active bus,the formulas for single-phase instantaneous voltage,load current,load power,as well as average power un-der disharmony operating conditions(DOCs)are *** characteristic indicators of the above electrical quantities are defined,which can measure the amplification and reduction de-grees of the above electrical quantities before and after ***,for the line directly connected to VSCUs,the formulas for single-phase instantaneous line current and power and the average power under DOCs are *** character-istic indicators of power flow are defined,which can be used to quantify the peak amplification impact of oscillation before and after ***,the case study on the Y-type three-terminal LPg under the single-disharmony and the multi-dis-harmony switching scenarios indicates that the long-period pow-er oscillation caused by disharmony may occur in the load flow at the non-active bus and the line *** oscillation causes a serious decrease in load capability and a significant amplifica-tion of the peak of line power oscillation.

关键词： New power system power oscillation disharmony voltage-source-controlled unit(VSCU) characteristic analysis

Recent progress in all-inorganic tin-based perovskite solar cells:a review

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Science China Chemistry 2024年第4期67卷 1117-1136页

作者： Minghao Wang yu Shi School of Electronics and Information Engineering Wuxi UniversityWuxi 214105China Institute of Advanced Materials Nanjing Tech UniversityNanjing 211816China

Recently,power conversion efficiency(PCE)of organic-inorganic hybrid perovskite solar cells(PSCs)has been improved to26.1%.However,the toxicity issue of lead still hinders the large-scale commercial production and application of lead(Pb)-based halide ***,environmentally friendly tin(Sn)-based perovskites have recently shown excellent *** them,the all-inorganic Sn-based perovskites,including CsSnX_(3) and Cs_(2)SnX_(6),have better stability,more suitable bandgap,and higher charge mobility,which have attracted more attention from researchers than organic-inorganic Sn-based hybrid ***,we review recent research progress on all-inorganic Sn-based perovskite materials and corresponding solar cell ***,we also summarize the current challenges and future research directions for this type of PSCs.

关键词： solar cells perovskite all-inorganic CsSnX_(3) Cs_(2)SnX_(6)