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Biomimetic chitin hydrogel via chemical transformation

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Nano Research 2024年第2期17卷 771-777页

作者： Rui-Rui Liu Qian-Qian Shi yu-feng Meng Yong Zhou Li-Bo Mao shu-Hong yu Division of Nanomaterials&Chemistry Hefei National Research Center for Physical Sciences at the MicroscaleDepartment of ChemistryInstitute of Biomimetic Materials&ChemistryAnhui Engineering Laboratory of Biomimetic MaterialsUniversity of Science and Technology of ChinaHefei 230026China College&Hospital of Stomatology Key Laboratory of Oral Diseases Research of Anhui ProvinceAnhui Medical UniversityHefei 230032China Department of Dental Implantology College&Hospital of StomatologyAnhui Medical UniversityHefei 230032China

Chitin hydrogel has been recognized as a promising material for various biomedical applications because of its biocompatibility and ***,the fabrication of strong chitin hydrogel remains a big challenge because of the insolubility of chitin in many solvents and the reduced chain length of chitin regenerated from *** herein introduce the fabrication of chitin hydrogel with biomimetic structure through the chemical transformation of chitosan,which is a water-soluble deacetylated derivative of *** reacetylation of the amino group in chitosan endows the obtained chitin hydrogel with outstanding resistance to swelling,degradation,extreme temperature and pH conditions,and organic *** chitin hydrogel has excellent mechanical properties while retaining a high water content(more than 95 wt.%).It also shows excellent antifouling performance that it resists the adhesion of proteins,bacteria,blood,and ***,as the initial chitosan solution can be feasibly frozen and templated by ice crystals,the chitin hydrogel structure can be either nacre-like or wood-like depending on the freezing method of the precursory chitosan *** to these anisotropic structures,such chitin hydrogel can exhibit anisotropic mechanics and mass transfer *** current work provides a rational strategy to fabricate chitin hydrogels and paves the way for its practical applications as a superior biomedical material.

关键词： chitin hydrogel biomimetic structure chemical stability mechanical strength antifouling

Near-zero-adhesion-enabled intact wafer-scale resist-transfer printing for high-fidelity nanofabrication on arbitrary substrates

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International Journal of Extreme Manufacturing 2024年第1期6卷 313-326页

作者： Zhiwen shu Bo feng Peng Liu Lei Chen Huikang Liang Yiqin Chen Jianwu yu Huigao Duan College of Mechanical and Vehicle Engineering National Engineering Research Centre for High Efficiency GrindingHunan UniversityChangsha 410082People’s Republic of China Greater Bay Area Institute for Innovation Hunan UniversityGuangzhou 511300People’s Republic of China School of Mechanical Engineering Hunan University of Science and TechnologyXiangtan 411201People’s Republic of China Shenzhen Research Institute Hunan UniversityShenzhen 518000People’s Republic of China

There is an urgent need for novel processes that can integrate different functional nanostructures onto specific substrates,so as to meet the fast-growing need for broad applications in nanoelectronics,nanophotonics,and fexible *** direct-lithography methods are difficult to use on fexible,nonplanar,and biocompatible ***,this fabrication is usually accomplished by nanotransfer ***,large-scale integration of multiscale nanostructures with unconventional substrates remains challenging because fabrication yields and quality are often limited by the resolution,uniformity,adhesivity,and integrity of the nanostructures formed by direct ***,we proposed a resist-based transfer strategy enabled by near-zero adhesion,which was achieved by molecular modification to attain a critical surface energy *** approach enabled the intact transfer of wafer-scale,ultrathin-resist nanofilms onto arbitrary substrates with mitigated cracking and wrinkling,thereby facilitating the in situ fabrication of nanostructures for functional *** this approach,fabrication of three-dimensional-stacked multilayer structures with enhanced functionalities,nanoplasmonic structures with~10 nm resolution,and MoS2-based devices with excellent performance was demonstrated on specific *** results collectively demonstrated the high stability,reliability,and throughput of our strategy for optical and electronic device applications.

关键词： resist-based transfer printing near-zero adhesion critical surface energy wafer-scale nanofabrication in situ fabrication optoelectronic devices

Chronic sleep deprivation induces alterations in DNA and RNA modifications by liquid chromatography-mass spectrometry analysis

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Chinese Chemical Letters 2024年第8期35卷 413-417页

作者： Tian feng yun-Ling Gao Di Hu Ke-yu yuan shu-Yi Gu Yao-Hua Gu Si-yu yu Jun Xiong yu-Qi feng Jie Wang Bi-feng yuan School of Public Health Research Center of Public HealthRenmin Hospital of Wuhan UniversityWuhan UniversityWuhan 430071China Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversityWuhan UniversityWuhan 430071China Key Laboratory of Magnetic Resonance in Biological Systems State Key Laboratory of Magnetic Resonance and Atomic and Molecular PhysicsNational Center for Magnetic Resonance in WuhanWuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences-Wuhan National Laboratory for OptoelectronicsWuhan 430071China University of Chinese Academy of Sciences Beijing 101408China Institute of Neuroscience and Brain Diseases Xiangyang Central HospitalAffiliated Hospital of Hubei University of Arts and ScienceXiangyang 441000China Phase I Clinical Trial Laboratory Zhongnan Hospital of Wuhan UniversityWuhan 430071China

Sleep deprivation(SD)is a widespread issue that disrupts the lives of millions of *** effects ini-tiate as changes within neurons,specifically at the DNA and RNA level,leading to disruptions in neuronal plasticity and the dysregulation of various cognitive functions,such as learning and *** acid epigenetic modifications that could regulate gene expression have been reported to play crucial roles in this ***,there is a lack of comprehensive research on the correlation of SD with nucleic acid epigenetic *** the current study,we aimed to systematically investigate the landscape of modifications in DNA as well as in small RNA molecules across multiple tissues,including the heart,liver,kidney,lung,hippocampus,and spleen,in response to chronic sleep deprivation(CSD).Using liquid chromatography-tandem mass spectrometry(LC-MS/MS)analysis,we characterized the dynamic changes in DNA and RNA modification profiles in different tissues of mice under CSD ***,we ob-served a significant decrease in the level of 5-methylcytosine(5mC)and a significant increase in the level of 5-hydroxymethylcytosine(5hmC)in the kidney in CSD *** RNA modifications,we observed an overall increased trend for most of these significantly changed modifications across six tis-sues in CSD *** study sheds light on the significance of DNA and RNA modifications as crucial epigenetic markers in the context of CSD-induced stress.

关键词： Sleep deprivation Epigenetics Mass spectrometry DNA modification RNA modification Small RNA

Hydrodynamic Characteristics of Undular Tidal Bores in the Qiantang River Based on Field Observations

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China Ocean Engineering 2024年第3期38卷 505-518页

作者： ZHANG shu-yu PAN Cun-hong ZHANG Shen-yang LI Ruo-hua CHENG Wenlong XIE Dong-feng Zhejiang Tongji Vocational College of Science and Technology Hangzhou 311231China Zhejiang Institute of Hydraulics and Estuary Hangzhou 310020China

Understanding the undular tidal bores in the Qiantang River is essential for effective river management and *** breaking tidal bores have been studied extensively, reports on undular tidal bores in the Qiantang Riverremain limited. Furthermore, observed data on undular tidal bores fulfilling the requirements of short measurementtime intervals, and spring, medium, and neap tide coverage, and providing detailed data for the global vertical stratificationof flow velocity are quite limited. Based on field observations at Qige in the Qiantang estuary, we analyzedthe characteristics of undular tidal bores. The results showed that the flooding amplitude (a) of the first wave isalways larger than its ebbing amplitude (b). Moreover, the vertical distribution of the maximum flood velocity exhibitesthree shapes, influenced by the tidal range, while that of the maximum ebb velocity exhibites a single shape. Duringthe initial phase of the flood tide in the spring and medium tides, the upper water body experiences multiple oscillatingchanges along the flow direction, corresponding to the alternating process of the crest and trough of the tide levelupon the arrival of the tidal bore. The tidal range is a crucial parameter in tidal bore hydrodynamics. By establishingthe relationship between hydrodynamic parameters and tidal range, other hydrodynamic parameters, such as the tidalbore height, maximum flood depth–averaged velocity, maximum flood stratified velocity at the measurement points,and duration of the flood tide current, can be effectively predicted, thereby providing an important reference for rivermanagement and maintenance.

关键词： tidal bores Qiantang Estuary tidal bore height tidal bore velocity propagation speed

Mismatch analysis of all-fiber coherent beam combiners based on the self-imaging effect

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High Power Laser Science and Engineering 2024年第2期12卷 1-15页

作者： yuefang Yan yu Liu Haoyu Zhang yuwei Li Chao Guo Qiang shu Wenhui Huang feng Jing Rumao Tao Laser Fusion Research Center China Academy of Engineering PhysicsMianyangChina Key Laboratory of Particle&Radiation Imaging(Tsinghua University) Ministry of EducationBeijingChina

All-fiber coherent beam combiners based on the self-imaging effect can achieve a near-perfect single laser beam,which can provide a promising way to overcome the power limitation of a single-fiber *** of the key points is combining efficiency,which is determined by various mismatches during fabrication.A theoretical model has been built,and the mismatch error is analyzed numerically for the first *** mismatch errors have been numerically studied with the beam quality and combining efficiency being chosen as the evaluation *** tolerance of each mismatch error for causing 1%loss is calculated to guide the design of the beam *** simulation results are consistent with the experimental results,which show that the mismatch error of the square-core fiber is the main cause of the efficiency *** results can provide useful guidance for the fabrication of all-fiber coherent beam combiners.

关键词： all-fiber coherent beam combination mismatch analysis self-imaging

Prediction for permeability index of blast furnace based on VMD-PSO-BP model

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Journal of Iron and Steel Research International 2024年第3期31卷 573-583页

作者： Xiao-jie Liu yu-jie Zhang Xin Li Zhi-feng Zhang Hong-yang Li Ran Liu shu-jun Chen School of Metallurgy and Energy North China University of Science and TechnologyTangshan 063210HebeiChina Chengde Branch HBIS Group Co.Ltd.Chengde 067000HebeiChina

The permeability index is one of the important production indicators to monitor the operation of blast *** is crucial to grasp the trends of changes in the new permeability index in *** the complex vibration spectrum of the permeability index,a prediction model of the permeability index based on the VMD-PSO-BP(variational mode decomposition-particle swarm optimization-back propagation)method was ***,the key factors that affect the permeability index of blast furnace were studied from multiple ***,the permeability index was divided into multiple sub-modes based on the difference of frequency bands by the VMD algorithm,and a PSO-BP prediction model was established for each ***,the prediction results of each sub-mode were summed to obtain the final *** results show that the composite prediction accuracy by using the VMD algorithm is 3%higher than that of the traditional prediction method,which has better applicability.

关键词： Big data-Blast furnace Air permeability Variational mode decomposition Particle swarm optimization Back propagation Model prediction

Derivation of Expanded Isospectral-Nonisospectral Integrable Hierarchies via the Column-vector Loop Algebra

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Acta Mathematicae Applicatae Sinica 2024年第3期40卷 778-800页

作者： Hai-feng WANG yu-feng ZHANG School of Science Jimei UniversityXiamen 361021China School of Mathematics China University of Mining and TechnologyXuzhou 221116China

A scheme for generating nonisospectral integrable hierarchies is *** on the method,we deduce a nonisospectral hierarchy of soliton equations by considering a linear spectral *** follows that the corresponding expanded isospectral and nonisospectral integrable hierarchies are deduced based on a 6 dimensional complex linear space ■.By reducing these integrable hierarchies,we obtain the expanded isospectral and nonisospectral derivative nonlinear Schr?dinger *** using the trace identity,the biHamiltonian structure of these two hierarchies are also ***,some symmetries and conserved quantities of the resulting hierarchy are discussed.

关键词： expanded isospectral-nonisospectral integrable hierarchies column-vector loop algebra bi-Hamiltonian structure symmetry

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Tackling barriers to scale up human papillomavirus vaccination in China:progress and the way forward

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Infectious Diseases of Poverty 2023年第5期12卷 81-86页

作者： Xue‑Lian Zhao Shang‑Ying Hu Jia‑Wei Hu Hong‑Hao Wang Tian‑Meng Wen yu‑shu feng You‑Lin Qiao Fang‑Hui Zhao Yong Zhang Department of Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College17 South Panjiayuan LaneP.O.Box 2258Beijing 100021China School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100730China Teaching and Research Section of Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical College17 South Panjiayuan LaneP.O.Box 2258Beijing 100021China

The human papillomavirus(HPV)vaccine is the first vaccine developed specifically targeting the prevention of cervical *** more than 15 years,China has expedited a series of efforts on research and development of the domestically manufactured HPV vaccines,producing local population-based evidence,promoting free HPV vaccination from pilots,and launching action plans to tackle barriers in the scale-up of HPV *** further roll out the HPV vaccination program in China,several challenges should be addressed to support the steps *** availability of more locally manufactured HPV vaccines,pricing negotiation and local evidence supporting the efficacy of one-dose schedule would greatly alleviate the continued supply and financial constraints in ***,more attention should be paid to girls living in low-resource areas and males to ensure equal access to the HPV ***,linkage to secondary prevention and further real-world monitoring and evaluation are warranted to inform effective cervical cancer prevention strategies in the post-vaccine era.

关键词： Human papillomavirus Vaccination Progress Challenge China

Multiscale observation in wide-spatial radar surveillance based on coherent FDA design

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Science China(Information Sciences) 2024年第2期67卷 232-252页

作者： Lei yu feng HE Yi SU College of Electronics Science National University of Defense Technology

Wide-spatial radar surveillance missions are challenging tasks, requiring an increased power budget and agility in transmission aimed at extracting information from multiple targets in different environments. These requirements necessitate high transmitting degrees of freedom(DOF) to achieve the objective of multiscale observation for specific tasks in specialized regions of interest. Herein, we exploit the multiscale observation ability in wide-spatial radar surveillance based on frequency diverse array(FDA)radar. The proposed method facilitates spatial anisotropic control of multiple radar resources, including the transmitting waveforms, beampattern, and bandwidth. By utilizing a coherent FDA radar, we offer principles for the selection of baseband waveforms, in addition to the quantitative design of the beampattern gain and optimal bandwidth from the perspective of detection. The feasibility of the proposed method is validated through numerical experiments, thus indicating the potential in wide-spatial radar surveillance. Moreover,this work can be regarded as a preliminary attempt to gauge the efficacy of the computational array, a novel academic concept.

关键词： multi-scale observation wide-spatial surveillance frequency diverse array (FDA) beampattern synthesis frequency diversity gain computational array