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Tungsten 2024年第2期6卷 394-409页

作者： yu-Lan Huang Bing Zhang yu-lian Li Li Wang Le Dong Jian Li College of Ocean Food and Biological Engineering Jimei UniversityXiamen 361021China College of Oceanology and Food Science Quanzhou Normal UniversityQuanzhou 362000China

Due to its properties of mutagenic,teratogenic,and carcinogenic,the detection of furazolidone(FZD)in aquaculture is of great importance for food safety and human *** this study,molecularly imprinted fi lms modifi ed with carboxylated multi-walled carbon nanotube-phosphomolybdic acid composite were used to fabricate an electrochemical sensor for the determination of *** nanocomposites were characterized using infrared spectroscopy,scanning electron microscopy,energy-dispersive X-ray spectroscopy,and X-ray diff *** electrochemical characteristics of the modifi ed electrodes were examined using electrochemical impedance spectroscopy,cyclic voltammetry,and diff erential pulse *** sensor exhibited exceptional catalytic *** calibration curves were acquired in the concentration range of 6 nmol·L^(−1)to 0.6μmol·L^(−1),with a limit of detection of 3.38 nmol·L^(−1).Additionally,the sensor proved successful in recognizing FZD in shrimp samples with satisfactory recoveries and *** method provides a strategy to construct a molecularly imprinted electrochemical sensing platform using nanomaterials,which has great promise in the field of food safety.

关键词： Phosphomolybdate Furazolidone Polyoxometalates Carboxylated multi-walled carbon nanotube Molecularly imprinted polymers Electrochemical sensor

Evidence-Based Dampness-Heat ZHENG(Syndrome) in Cancer: Current Progress toward Establishing Relevant Animal Model with Pancreatic Tumor

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Chinese Journal of Integrative Medicine 2024年第1期30卷 85-95页

作者： JIAO Ju-ying CHENG Chien-shan CAO Zhang-qi CHEN lian-yu CHEN Zhen Department of Integrative Oncology Fudan University Shanghai Cancer CenterShanghai(200032)China Department of Oncology Shanghai Medical CollegeFudan UniversityShanghai(200032)China

Cancer is one of the deadliest diseases affecting the health of human beings. With limited therapeutic options available, complementary and alternative medicine has been widely adopted in cancer management and is increasingly becoming accepted by both patients and healthcare workers alike. Chinese medicine characterized by its unique diagnostic and treatment system is the most widely applied complementary and alternative medicine. It emphasizes symptoms and ZHENG(syndrome)-based treatment combined with contemporary disease diagnosis and further stratifies patients into individualized medicine subgroups. As a representative cancer with the highest degree of malignancy, pancreatic cancer is traditionally classified into the "amassment and accumulation". Emerging perspectives define the core pathogenesis of pancreatic cancer as "dampness-heat" and the respective treatment "clearing heat and resolving dampness" has been demonstrated to prolong survival in pancreatic cancer patients, as has been observed in many other cancers. This clinical advantage encourages an exploration of the essence of dampness-heat ZHENG(DHZ) in cancer and investigation into underlying mechanisms of action of herbal formulations against dampness-heat. However, at present, there is a lack of understanding of the molecular characteristics of DHZ in cancer and no standardized and widely accepted animal model to study this core syndrome in vivo. The shortage of animal models limits the ability to uncover the antitumor mechanisms of herbal medicines and to assess the safety profile of the natural products derived from them. This review summarizes the current research on DHZ in cancer in terms of the clinical aspects, molecular landscape, and animal models. This study aims to provide comprehensive insight that can be used for the establishment of a future standardized ZHENG-based cancer animal model.

关键词： cancer Chinese medicine syndrome ZHENG dampness-heat syndrome animal model pancreatic tumor evaluation methods

Values of macular ganglion cell-inner plexiform layer and 10-2 visual field measurements in detecting and evaluating glaucoma

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 852-860页

作者： Hai-Jian Hu Ping Li Bin Tong yu-lian Pang Hong-Dou Luo Fei-Fei Wang Chan Xiong yu-Lin yu Hai He Xu Zhang Affiliated Eye Hospital of Nanchang University Jiangxi Research Institute of Ophthalmology and Visual ScienceJiangxi Clinical Research Center for Ophthalmic DiseaseJiangxi Branch of National Clinical Research Center for Ocular DiseasesNanchang 330006Jiangxi ProvinceChina Wuhan Children’s Hospital(Wuhan Maternal and Child Healthcare Hospital) Tongji Medical CollegeHuazhong University of Science&TechnologyWuhan 430015Hubei ProvinceChina

AIM:To assess the performance of macular ganglion cell-inner plexiform layer thickness(mGCIPLT)and 10-2 visual field(VF)parameters in detecting early glaucoma and evaluating the severity of advanced ***:Totally 127 eyes from 89 participants(36 eyes of 19 healthy participants,45 eyes of 31 early glaucoma patients and 46 eyes of 39 advanced glaucoma patients)were *** relationships between the optical coherence tomography(OCT)-derived parameters and VF sensitivity were *** with early glaucoma were divided into eyes with or without central 10°of the VF damages(CVFDs),and the diagnostic performances of OCT-derived parameters were ***:In early glaucoma,the mGCIPLT was significantly correlated with 10-2 VF pattern standard deviation(PSD;with average mGCIPLT:β=-0.046,95%CI,-0.067 to-0.024,P<0.001).In advanced glaucoma,the mGCIPLT was related to the 24-2 VF mean deviation(MD;with average mGCIPLT:β=0.397,95%CI,0.199 to 0.595,P<0.001),10-2 VF MD(with average mGCIPLT:β=0.762,95%CI,0.485 to 1.038,P<0.001)and 24-2 VF PSD(with average mGCIPLT:β=0.244,95%CI,0.124 to 0.364,P<0.001).Except for the minimum and superotemporal mGCIPLT,the decrease of mGCIPLT in early glaucomatous eyes with CVFDs was more severe than that of early glaucomatous eyes without *** area under the curve(AUC)of the average mGCIPLT(AUC=0.949,95%CI,0.868 to 0.982)was greater than that of the average circumpapillary retinal nerve fiber layer thickness(cpRNFLT;AUC=0.827,95%CI,0.674 to 0.918)and rim area(AUC=0.799,95%CI,0.610 to 0.907)in early glaucomatous eyes with CVFDs versus normal ***:The 10-2 VF and mGCIPLT parameters are complementary to 24-2 VF,cpRNFLT and ONH parameters,especially in detecting early glaucoma with CVFDs and evaluating the severity of advanced glaucoma in group level.

关键词： 10-2 visual field ganglion cell-inner plexiform layer retinal nerve fiber layer thickness glaucoma

Graphitic carbons: preparation, characterization,and application on K-ion batteries

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Rare Metals 2024年第9期43卷 4056-4075页

作者： Kang-Zhe Cao Jia-Hui Ma yu-lian Dong yu Duan Run-Tian Zheng Dharani Bundhooa Hui-Qiao Liu Yong Lei College of Chemistry and Chemical Engineering Xinyang Normal University Xinyang Key Laboratory of Low-Carbon Energy Materials Fachgebiet Angewandte Nanophysik Institut für Physik & IMN MacroNano Technische Universit?t Ilmenau Laboratory of Inorganic Materials Chemistry (CMI) University of NamurB-5000 Namur

K-ion batteries(KIBs) have drawn much attention due to the abundant potassium reserves and wide accessibility as well as high energy density, which can be designed for large-scale energy storage systems. As the most promising anode materials for KIBs, graphitic carbons, especially those with an intermediate structure between the crystalline graphite and amorphous carbons become a hot research focus because of the improved rate capability and enhanced diffusion-controlled capacity at low voltage regions. Herein, we first review the structures of graphitic carbons in the view of graphitic domains and the structure changes in their K-ion intercalation compounds. Then, we summarize the preparation mechanisms and characterizations of graphitic carbons and the influence factors in their degree of graphitization. Furtherly, we illustrate the strategies to optimize their K-ion storage properties from four aspects, namely graphitic domain design, microstructure engineering, electrochemical active component regulation, and defect engineering. Finally, we propose the issues that urgently need to be solved in graphitic carbons and the possible solutions. We hope that this view could offer some inspiration for the further designing and optimizing of graphitic carbons for practical KIBs.

关键词： Anodes

Efficacy comparison of fruquintinib,regorafenib monotherapy or plus programmed death-1 inhibitors for microsatellite stable metastatic colorectal cancer

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2449-2462页

作者： Tian-Qi An Hui Qiu Quan-Bo Zhou Hong Zong Shuang Hu yu-Gui lian Rui-Hua Zhao Department of Oncology The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina Department of Hepato-Pancreato-Biliary Surgery Peking University Cancer Hospital and InstituteBeijing 100000China Department of Colorectal Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450000Henan ProvinceChina

BACKGROUND Regorafenib(R)and fruquintinib(F)are the standard third-line regimens for colorectal cancer(CRC)according to the National Comprehensive Cancer Network guidelines,but both have limited *** phase 2 trials have indicated that R or F combined with immune checkpoint inhibitors can reverse immunosuppression and achieve promising efficacy for microsatellite stable or proficient mismatch repair(MSS/pMMR)*** to the lack of studies comparing the efficacy between F,R,F plus programmed death-1(PD-1)inhibitor,and R plus PD-1 inhibitors(RP),it is still unclear whether the combination therapy is more effective than *** To provide critical evidence for selecting the appropriate drugs for MSS/pMMR metastatic CRC(mCRC)patients in clinical *** A total of 2639 CRC patients were enrolled from January 2018 to September 2022 in our hospital,and 313 MSS/pMMR mCRC patients were finally *** A total of 313 eligible patients were divided into F(n=70),R(n=67),F plus PD-1 inhibitor(FP)(n=95)and RP(n=81)*** key clinical characteristics were well balanced among the *** median progression-free survival(PFS)of the F,R,FP,and RP groups was 3.5 months,3.6 months,4.9 months,and 3.0 months,*** median overall survival(OS)was 14.6 months,15.7 months,16.7 months,and 14.1 *** FP regimen had an improved disease control rate(DCR)(P=0.044)and 6-month PFS(P=0.014)and exhibited a better trend in PFS(P=0.057)compared with F,and it was also significantly better in PFS than RP(P=0.030).RP did not confer a significant survival benefit;instead,the R group had a trend toward greater benefit with OS(P=0.080)compared with *** significant differences were observed between the R and F groups in PFS or OS(P>0.05).CONCLUSION FP is superior to F in achieving 6-month PFS and DCR,while RP is not better than *** has an improved PFS and 6-month PFS compared with RP,but F and R had similar clinical ***,FP may be a

关键词： Colorectal cancer Fruquintinib Regorafenib Programmed death-1 inhibitor Real-world

The Impact of Storyline Complexity on L2 Learners’Written Performance

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Journal of Literature and Art Studies 2024年第5期14卷 369-372页

作者： CHEN yu-lian Wuhan University of Technology WuhanChina

Task-based Language Teaching(TBLT)research has provided ample evidence that cognitive complexity is an important aspect of task design that influences learner’s performance in terms of fluency,accuracy,and syntactic *** the substantial number of empirical investigations into task complexity in journal articles,storyline complexity,one of the features of it,is scarcely *** research mainly focused on the impact of storyline complexity on learners’oral performance,but the impact on learners’written performance is less ***,this study aims at investigating the effects of narrative complexity of storyline on senior high school students’written performance,as displayed by its complexity,fluency,and *** present study has important pedagogical *** is,task design and assessment should make a distinction between different types of narrative *** example,the task with single or dual *** on task complexity may contribute to informing the pedagogical choices made by teachers when prioritizing work with a specific linguistic dimension.

关键词： storyline complexity narrative writing task complexity L2 writers

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“非洲独龙玉”的矿物成分及谱学特征

光谱学与光谱分析 2024年第6期44卷 1676-1683页

作者：余炼钢郑金宇德宏师范高等专科学校艺术学院云南德宏678400 中国地质大学(武汉)珠宝学院湖北武汉430074

“非洲独龙玉”是近年来滇西珠宝市场上涌现的新兴玉石品种。其鲜艳绿色呈脉状和团絮状分布于无色至灰白色基体上,局部存在红褐色。品质优于云南怒江州“独龙玉”,市场前景引起业界广泛关注,但其宝石学特征及矿物种属尚不清楚。运用红... 详细信息

“非洲独龙玉”是近年来滇西珠宝市场上涌现的新兴玉石品种。其鲜艳绿色呈脉状和团絮状分布于无色至灰白色基体上,局部存在红褐色。品质优于云南怒江州“独龙玉”,市场前景引起业界广泛关注,但其宝石学特征及矿物种属尚不清楚。运用红外光谱仪、拉曼光谱仪、X射线粉晶衍射仪、扫描电子显微镜及能谱、X射线荧光光谱仪、紫外-可见光谱仪等测试方法对其矿物组成及结构特征、化学成分、谱学特征及颜色成因等进行了研究。红外光谱测试表明该玉石的绿色部分显示白云母与石英的红外特征混合谱,其中3623、694、1080和1619 cm^(-1)处特征吸收峰指示白云母。拉曼光谱测试显示玉石基体部分在204、262、355、395和463 cm^(-1)处具α-石英特征峰,绿色部分在261、395、694、3623 cm^(-1)处具白云母特征峰,表面金属光泽矿物在343、379和437 cm^(-1)处具黄铁矿特征峰,局部浸染状橙黄-红褐色矿物在224、295、409、493和610 cm^(-1)处具赤铁矿特征峰。X射线粉晶衍射测试在3.48、2.98、2.56处特征衍射峰指示为2M 1型白云母。扫描电子显微镜及能谱面扫描显示白云母呈纤柱状、鳞片状集合体,单颗粒长约25~40μm,宽约2~4μm;少量杂质矿物辉砷镍矿呈近似立方体晶形,粒径约为10~15μm,由黄铁矿蚀变作用形成,其中Fe、Co部分类质同像替代Ni,As含量高于S,指示为高温热液矿床成因。综合化学成分及紫外-可见光谱特征表明,致色矿物白云母含Ba、Cr,不含Fe,其中Cr为致色元素。除颜色特征外,利用多种谱学的方法揭示了“非洲独龙玉”与云南怒江“独龙玉”在杂质矿物、化学成分及致色元素方面的差异,可作为区分二者的有效证据,同时丰富了天然绿色石英质玉的成分信息和谱学特征数据,亦为进一步做“非洲独龙玉”的产地溯源及成矿地质条件背景研究奠定了理论基础。

关键词： “非洲独龙玉” 矿物组成辉砷镍矿颜色成因谱学特征

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单片机在智能仪器仪表中的应用探究

仪器仪表用户 2024年第1期31卷 104-106页

作者：连瑀福州软件职业技术学院

近年来，我国计算机技术发展迅速，单片机技术越来越成熟，在智能测量领域的应用不断扩大。单片机具有占地面积小、数据计算能力强、数据操作能力强等优点，可以提供更完善的测量能力。未来单片机将朝着高速、高效、高精度的方向发展，... 详细信息

近年来，我国计算机技术发展迅速，单片机技术越来越成熟，在智能测量领域的应用不断扩大。单片机具有占地面积小、数据计算能力强、数据操作能力强等优点，可以提供更完善的测量能力。未来单片机将朝着高速、高效、高精度的方向发展，同时工作效率和性能也会得到提升,单片机的应用将不断丰富其功能并提高其操作的灵敏度。

关键词：单片机智能仪器仪表应用探究

Eruptive xanthomas in a patient with severe hypertriglyceridemia:A case report

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World Journal of Clinical Cases 2024年第16期12卷 2842-2846页

作者： Ci Ren Ling Zhu Yan-Chao Niu lian-yu Tu Zhou-Feng Jin Jian Zhang Department of Dermatological Surgery Shenyang Seventh People’s HospitalShenyang 110003Liaoning ProvinceChina Department of Medical Technology Sichuan Nursing Vocational CollegeChengdu 610100Sichuan ProvinceChina Department of Dermatovenereology Chengdu Second People’s HospitaChengdu 610021Sichuan ProvinceChina Department of Plastic Surgery Shenyang Mingliu Plastic Surgery and Aesthetics HospitalShenyang 110000Liaoning ProvinceChina

BACKGROUND Xanthomatosis,a metabolic disorder causing yellow growths(xanthomas),poses challenges in lipid *** case study introduces the first documented instance within China's Yi population,emphasizing the need to explore dietary habits and treatment strategies tailored to this specific *** SUMMARY Xanthomatosis is a metabolic disorder where lipid metabolism goes awry,resulting in the development of yellowish growths called xanthomas.A male patient,47 years of age,from China's Yi population,who is obese,visited our dermatology clinic complaining of widespread,non-painful rashes that have been present for two *** patient works as a chef and has a diet that frequently includes oily and greasy *** case represents the initial documentation of xanthomatosis within the Yi population in China,offering a theoretical foundation for understanding dietary patterns and treatment options specific to the Yi *** The first report of xanthomatosis in the Yi population in China lays a theoretical foundation for understanding Yi dietary patterns and treatment.

关键词： Eruptive xanthomas Hypertriglyceridemia Yi ethnicity Dermatology Chef Case report

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观察机制对囚徒困境博弈合作水平的影响

控制与决策 2024年第1期39卷 311-318页

作者：蒋贤惠蒋玉莲黄勤珍西南民族大学电气工程学院成都610041 西南民族大学国家民委电子信息重点实验室成都610041

在演化博弈论中,合作有利于增加群体收益.目前,大量的研究工作都在关注合作水平的提高,但忽视了理论与实际的相关性,同时策略更新时间仅限于一个点上的收益.为此,引入完全同步、相对同步、高斯异步、指数异步4种观察机制模型,考虑智能... 详细信息

在演化博弈论中,合作有利于增加群体收益.目前,大量的研究工作都在关注合作水平的提高,但忽视了理论与实际的相关性,同时策略更新时间仅限于一个点上的收益.为此,引入完全同步、相对同步、高斯异步、指数异步4种观察机制模型,考虑智能体观察期内所获得的平均收益.随后,采用蒙特卡洛方法进行实验仿真,并分析各观察机制对囚徒困境博弈合作水平的影响.结果表明:在4种模型中都存在观察时间阈值,此时合作水平将达到峰值;最高合作水平在指数异步模型中实现;高斯异步模型中,合作水平与方差成正相关;智能体间的异质性也对合作产生积极影响.这项研究有助于打破传统研究收益的局限,促进合作水平的提高.仿真实验结果为支持社会群体合作提供了一定的理论依据.

关键词：观察机制囚徒困境博弈异质性合作水平平均收益蒙特卡洛方法