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Role of Vascular Endothelial Growth Factor-C during Stem Cell Therapy Using Autologous Bone Marrow Mononuclear Cells in Patients with Lower Limb Lymphedema

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Stem Cell Discovery 2023年第1期13卷 1-16页

作者： Ahmed M. Ismail Said M. Abdou Amira Yousef yousra sameh M. Attia Ahmed Badran Mohamed I. Adel El Eissawy Asmaa E. Bedeer Wesam M. Salama Ahmed O. Korany Vascular Surgery Department Faculty of Medicine Tanta University Tanta Egypt Clinical Pathology Department Faculty of Medicine Tanta University Tanta Egypt Pathology Department Faculty of Medicine Tanta University Tanta Egypt Faculty of Science Tanta University Tanta Egypt Vascular Surgery Department Alexandria University Alexandria Egypt

Introduction: Vascular endothelial growth factor-C (VEGF-C) is the primary lymphangiogenic factor that stimulates lymphangiogenesis by signaling via specific receptor, vascular endothelial growth factor receptor 3 (VEGFR3). This study was conducted to evaluate the change in the level of VEGF-C before and after autologous bone marrow mononuclear cell transplantation for treatment of Lower limb lymphedema. Patient and methods: Forty patients with lower limb lymphedema were divided into two groups. Group I included 20 patients with chronic lower limb lymphedema who underwent autologous bone marrow mononuclear cell transplantation. Group II included 20 patients with chronic lower limb lymphedema who were exposed only to compression therapy as a control group. VEGF-C level in the diseased limbs was measured in both groups at the beginning of the study then 3 and 6 months respectively. Results: Group I included 20 patients, 8 patients were male (40%) and 12 patients were females (60%) with mean age 29.5 ± 12.15 while group II included 20, 10 patients were male (50%) and 10 patients were females (50%) with mean age 39.5 ± 11.5. In group I, the specimens were taken at 3 and 6 months after transplantation showed a marked decrease in the VEGF-C level with statistically significant p value, 0.02 and 0.001 respectively. In group II the level of VEGF-C after compression therapy alone at 3 and 6 months interval showed fluctuation with statistically non-significant p value, 0.64 and 0.55 respectively. Conclusion: VEGF-C is essential for regulation of lymphangiogenesis. The level of VEGF-C was found elevated in patients with lymphedema and decrease after autologous mononuclear bone marrow cells, however these results were statically non-significant.

关键词： Lymphangiogenesis VEGF-C Bone Marrow Mononuclear Cells

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Determination and Analysis of Optical Constant of Annealed Sn_2Sb_2S_5 Thin Films

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Acta Metallurgica Sinica(English Letters) 2015年第5期28卷 656-662页

作者： yousra Fadhli Adel Rabhi Mounir Kanzari Laboratoire de Photovoltaque et Matriaux Semi-Conducteurs ENIT BP 37 Le belvdère 1002 Tunis Tunisia

The effects of annealing on structural, optical and electrical properties of Sn2Sb2S5 thin films were studied. Sn2Sb2S5 thin films were deposited on no-heated glass substrates by single source vacuum evaporation method. The as- deposited films were annealed in air for 1 h at 100, 200 and 300 ℃. XRD study shows that annealed films are crystallized according to the preferential orientation （602）. Optical measurements show that the thin films have relatively high absorption coefficients in the range of 10s-106 cm-1 in the energy range of 2-3.25 eV. It is also found that Sn2Sb2S5 exhibit two optical direct transitions. The models of Wemple-DiDomenico and Spitzer-Fan were applied for the analysis of the dispersion of the refractive index and the determination of the optical and dielectric constants. The electrical resistivity measurements are recorded, and two activation energy values are determined. The layers annealed at 200 and 300 ℃ exhibit a resistive hysteresis behavior. The properties reported here offer perspective to Sn2SbES5 for its application in many advanced technologies.

关键词： Sn2Sb2S5 thin films Optical constants Electrical properties

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Paleontological Records of Holocene Environmental Changes offshore, Egypt

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Journal of Ocean University of China 2019年第6期18卷 1382-1394页

作者： Rehab ELSHANAWANY yousra MOHAMED Mohamed IAIBRAHIM MARUM Leobener StraβeUniversity of BremenD-28359 BremenGermany Faculty of Science Alexandria UniversityMoharam Bey 21511Egypt

Paleontological and sedimentological analyses were carried out in sediment core from southeastern Mediterranean Sea,offshore Egypt to reconstruct the past environmental changes in trophic state and temperature during *** achieve our goals,grain size,total organic carbon,planktic and benthic foraminifera,dinoflagellate cysts have been *** micropalaentological studies have been done in the studied area and none of them used the combined proxies of benthic foraminifera and dinoflagellate *** combined proxies reflects more comprehensive paleoenvironmental *** and abiotic data have been analysed with multivariate technique including Redundancy Analysis(RDA).Diversity indices such as:Fisher alpha index(α)and Shannon index(H)have been *** foraminiferal study yields 9 planktic species and 10 benthic *** assemblages have low species diversity indices especially at sapropel layer *** sapropels are layers with elevated organic carbon concentrations that contrast with surrounding organic poor *** occur periodically in sedimentary sequences of the last millions years,which have been the subject of extensive previous *** Analysis(RDA)yields two groups of foraminiferal assemblages depending on the changes of total organic carbon and clay *** dinocysts study yields 15 species,the majority of cyst types belonging to the order *** association of dinoflagellate cyst shows two depositional phases in the *** sapropel layer S1,with anoxic condition and warmer temperature,is recorded at depth 28-46 cm where heterotrophic taxa dominate and the post-sapropel layer is recorded at depth 0-28 cm;where autotrophic taxa dominate.

关键词： dinoflagellate cysts paleoenvironmental changes planktic and benthic foraminifera offshore Egypt

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Effect of ultrasonic irradiation and /or halogenation on the catalytic performance of γ-Al_2O_3 for methanol dehydration to dimethyl ether

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燃料化学学报 2013年第9期41卷 1077-1084页

作者： sameh M.K.Aboul-Fotouh Ain Shams University Faculty of EducationChemistry DepartmentRoxyCairo 11566Egypt

Dimethyl ether(DME) is amongst one of the most promising alternative,renewable and clean fuels being considered as a future energy *** this study,the comparative catalytic performance of the halogenated γ-Al 2 O 3 prepared from two halogen precursors(ammonium chloride and ammonium fluoride) is *** impact of ultrasonic irradiation was evaluated in order to optimize both the halogen precursor for the production of DME from methanol in a fixed bed *** catalysts were characterized by SEM,XRD,BET and NH *** reaction conditions where the temperature ranged from 200 to 400 ℃ with a WHSV = 15.9 h-1was found that the halogenated catalysts showed higher activity at all reaction ***,the halogenated alumina catalysts prepared under the effect of ultrasonic irradiation showed higher performance of γ-Al 2 O 3 for DME *** chlorinated γ-Al 2 O 3 catalysts showed a higher activity and selectivity for DME production than fluorinated versions.

关键词：化学原理方法化学动力学

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Production of dimethylether(DME) as a clean fuel using sonochemically prepared CuO and /or ZnO- modified γ- alumina catalysts

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燃料化学学报 2014年第3期42卷 350-356页

作者： sameh M.K.Aboul-Fotouh Ain Shams University Faculty of EducationChemistry Department

The catalytic conversion of methanol to dimethylether(DME)was studied over CuO/Al2O3,ZnO/Al2O3and ZnOCuO/Al2O3nanocatalysts prepared in presence or absence of ultrasonic *** catalysts were characterized by X-ray diffraction(XRD),surface characterization method(BET),scanning electron microscope(SEM),H2-temperature programmed reduction(H2-TPR)and temperature programmed desorption of ammonia(NH3-TPD).The experimental results show that during catalytic dehydration of methanol to dimethylether,the activities of the CuO/Al2O3,ZnO/Al2O3and ZnO-CuO/Al2O3catalysts prepared using ultrasonic treatment are much higher than those prepared in absence of *** shows that the use of ultrasonication results in much smaller *** and XRD show that the ultrasonication increases the surface area and pore volume of the catalysts.H2-TPR profiles indicated that reducibility of the sonicated nanocatalysts is carried out at lower ***3-TPD shows that ultrasound irradiation has enhanced the acidity of the nanocatalyst and hence enhanced catalytic performance for DME formation.

关键词： DME 燃料化学氧化铜氧化锌

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Methanol conversion to DME as a blue fuel：The beneficial use of ultrasonic irradiation for the preparation of CuO/H-MOR nanocatalyst

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燃料化学学报 2014年第11期42卷 1340-1350页

作者： sameh M.K. Aboul-Fotouh Ain Shams University Faculty of Education Chemistry Department Roxy Cairo 11566 Egypt

Methanol conversion to DME was investigated over CuO /H-MOR nanocatalyst prepared by precipitation and /or by precipitation flowed by ultrasonic irradiation methods. BET,XRD,SEM,NH3-TPD and H2-TPR techniques were used to characterize nanocatalysts. The effective ultrasonication factors encountered during carrying out the dehydration of methanol on Cuo /H-MOR zeolite catalysts to produce dimethylether are studied in the present work. These factors include: the type of ultrasonication media,the ultrasonication time,and the fixed weight of the solid catalyst per the volume of the ultrasonication liquid media( Wcatalyst/ Vliquidratio). XRD showed that structure of H-MOR is not damaged even after it is loaded with CuO nanoparticles or with ultrasonication. H2-TPR profiles indicated that reducibility of sonicated CuO / H-MOR nanocatalyst is higher than non-sonicated catalyst. It is found that employing ultrasound energy for 60 min has the highest influence on the surface properties of nanocatalyst and its catalytic performance( activity and stability) of CuO / H-MOR catalyst. Surface morphology( SEM) of the sonicated CuO /H-MOR catalysts have clarified that methanol by itself used as an ultrasonication medium gives the best results concerning the homogeneity of particle sizes compared to the non-sonicated catalyst,where large agglomerates and non-homogeneous clusters appeared. Water used as a sonication medium showed many large agglomerates in addition to some smaller particles resulted in lowcatalytic activity. The different alcohols and( Wcatalyst/ Vliquid) ratio were examined to give precise correlation with the catalytic activity of the sonicated CuO / H-MOR zeolite catalyst. These findings certified that ultrasonication has a deep effect on the surface morphology and hence on the catalytic behavior of the dehydration of methanol to DME. NH3-TPD shows that ultrasound irradiation has enhanced the acidity of CuO / H-MOR catalyst and hence it's catalytic performance for

关键词：燃料化学催化原理催化反应

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Recurrent anal fistulas: When, why, and how to manage?

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World Journal of Clinical Cases 2020年第9期8卷 1586-1591页

作者： sameh Hany Emile Colorectal Surgery Unit General Surgery DepartmentMansoura University HospitalsMansoura UniversityMansoura 35516Egypt

Anal fistula is a commonly encountered anal condition in the surgical *** being a benign condition,anal fistula remains to represent a surgical challenge,particularly the complex type of *** of the common complications of anal fistula surgery is the persistence or recurrence of the pathology,both defined as failure of *** anal fistulas after previous surgery represent an even more challenging problem since they are usually associated with a higher risk of re-recurrence and continence *** present review aimed to shed light on various aspects of recurrent anal fistulas,including the different definitions of failure after surgery,risk factors of recurrence,problems associated with management of recurrent fistulas,and assessment and treatment of recurrent anal fistulas.

关键词： Recurrent Anal Fistula When How Manage

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Large scale hybrid Monte Carlo simulations for structure and property prediction

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npj Computational Materials 2018年第1期4卷 1-7页

作者： Sergei Prokhorenko Kruz Kalke yousra Nahas Laurent Bellaiche Physics Department and Institute for Nanoscience and Engineering University of ArkansasFayettevilleAR 72701USA

The Monte Carlo method is one of the first and most widely used algorithms in modern computational *** condensed matter physics,the particularly popular flavor of this technique is the Metropolis Monte Carlo *** being incredibly robust and easy to implement,the Metropolis sampling is not well-suited for situations where energy and force evaluations are computationally *** search for a more efficient technique,we here explore the performance of Hybrid Monte Carlo sampling,an algorithm widely used in quantum electrodynamics,as a structure prediction scheme for systems with long-range *** results show that the Hybrid Monte Carlo algorithm stands out as an excellent computational scheme that can not only significantly outperform the Metropolis sampling but also complement molecular dynamics in materials science applications,while allowing ultra-large-scale simulations of systems containing millions of particles.

关键词： prediction property scheme

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Interactive platform for peer review:A proposal to improve the current peer review system

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World Journal of Clinical Cases 2021年第6期9卷 1247-1250页

作者： sameh Hany Emile General Surgery Department Mansoura University HospitalsMansoura UniversityMansoura 35516Egypt

Peer review is the cornerstone in scientific *** peer review has paramount importance in ensuring the quality of the published literature,it still has a number of *** present manuscript proposes a new method to improve the current peer review system by providing an interactive,dynamic platform that allows direct,anonymous interaction between the authors of submitted manuscripts and the *** real-time interaction may help eliminate any problems related to misunderstanding or misinterpretation of the reviewer’s comments or the authors’response,and would save time while keeping the identity of both parties anonymous.

关键词： Peer Review Interactive Proposal System Improve

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The Impact of the Superposition Coding Concept on Admission Control Strategy in OFDMA-Based Network

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China Communications 2018年第6期15卷 68-83页

作者： Yosra Abbes sameh Najeh Hichem Besbes Research Laboratory COSIM Sup'Com University of Carthage

Admission control is a key mechanism to manage the increasing number of the simultaneous demanding services, requiring a desired Quality of Service(QoS) in a spectrum efficient manner. To address this issue,we investigate in this work, the use of the superposition coding technique to increase the system capacity through multiuser diversity exploitation. We propose a novel joint admission control and superposition coding formalism based on different utility functions:Opportunistic(OPSC), Great Fairness(GFSC)and Proportional Fairness(PFSC). Simulation results show the superiority of our proposed approaches over other by providing higher mean of served VoIP users and higher throughput while maintaining an average VoIP packet transmission delay lower than 0.6 ms.

关键词： admission control QoS superposition coding opportunistic great fairness proportional fairness VoIP users

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