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Health 2021年第8期13卷 830-838页

作者： Roberto S. Zeballos Luciana N. L. Cruz Vânia C. R. Brilhante Adriana V. Lima Carlliane L. L. P. Martins Karla N. A. Lima Michele C. G. L. Leão Belinete L. Cruz Alessandra B. Dysarz Paulo C. B. Lobato Erika S. Almeida Rute A. P. Costa Klevison C. Araújo Augusto C. C. Almeida Leônidas B. D. Junior Kathia O. Harada Rita H. V. S. Araújo Elaine X. Prestes Ivete M. S. Souza Avany M. P. Pereira Antônio B. M. A. Rocha Iracema A. Estevão Fagnei I. C. Carvalho Paulo M. P. Melo Clinical Care Sao Paulo Brazil Instituto de Ciencias da Saude Faculdade de Medicina Universidade Federal do Para Belem Brazil Fundacao Publica Estadual Hospital de Clinicas Gaspar Vianna Belem Brazil Hospital da Policia Militar do Para Belem Brazil Imunoclinic Belem Brazil Universidade Estadual do Para Fundacao Santa Casa de Misericordia do Para Belem Brazil Clinica Barros Cirurgia Plastica Belem Brazil Secretaria de Estado de Saude Publica Castanhal Brazil Centro de Tratamento Oncologico Belem Brazil Sociedade Brasileira de Valorizaç ã o das Sociedades Medicas—SOBEMED S&#227 o Paulo Brazil Clinica de Nutrologia Sao Luiz Brazil Hospital Nipo Brasileiro de Olhos Belem Brazil Centro de Ciencias Biologicas e da Saude Universidade do Estado do Para Belem Brazil Hospital Regional do Baixo Amazonas Santarem Brazil Clinica Vallinoto Secretaria de Saude de Barcarena Barcarena Brazil Estrategia Saude da Familia Secretaria Municipal de Saude de Ananindeua Centro Universitario do Estado do Para Belem Brazil A. M. P. Endocrinologia Belem Brazil Instituto Avertano Rocha Belem Brazil Departamento de Neurocirurgia Hospital Militar de Area De Sao Paulo Sao Paulo Brazil

In the face of new diseases, medicine needs to reinvent itself in order to contain and control epidemics, such as the one we have recently faced, COVID-19, a disease with a wide spectrum of clinical severity. A new moment has been established, since the application of well-known, effective and safe medications for other diseases, has shown high success rates in the treatment of COVID-19. Thereunto, studies with early intervention are needed, which can change the unfavorable outcome of patients. In this article, we report the successful experience using an oral strategy during the collapse of Belem (Para, Brazil) Health System. Two hundred and ten patients were diagnosed with respiratory failure due to COVID-19, with no option of hospital treatment due to lack of beds and resources. These patients were then started on therapeutic regimen consisting of 40 mg prednisolone, 40 mg enoxaparin and macrolides (500 mg clarithromycin, 500 mg axetylcefuroxime) associated and followed in outpatient facilities. Two hundred and eight patients had an excellent therapeutic response and there were only two fatalities. These results push research boundaries, valuing outpatient treatment with early use of prednisolone in the initial pulmonary phase, preventing severe COVID-19 pneumonitis. Adoption of the proposed treatment intends to reduce the need for hospitalization, as well as lethality, with social robust benefits and incalculable economic savings since involves the use of accessible, safe and not expensive medications.

关键词： COVID-19 Corticosteroids Pulmonary Inflammatory Phase Collapse Brazil

Faujasite zeolite decorated with cobalt ferrite nanoparticles for improving removal and reuse in Pb2+ions adsorption

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可溶性ST2可预测收缩功能不全性心力衰竭者猝死风险

Chinese journal of Chemical Engineering 2020年第7期

作者： Elaine C.Paris jo?o O.D.Malafatti Henrique C.Musetti Alexandra Manzoli Alessandra Zenatti Márcia T.Escote

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心血管病学进展 2010年第6期31卷 925-925页

作者： Figal DAP Llanos jo Tornel PL 袁志敏（摘译）不详四川省第五人民医院

心脏猝死(SCD)为慢性心力衰竭(HF)者的常见并发症,因此预测中重度慢性HF者继发SCD风险尤显重要。既往研究显示.血中可溶性ST2(白介素-1受体家族成员之一)水平升高与急性HF者远期不良预后增加有关。然而关于血中可溶性ST2(sST2)可否预测... 详细信息

心脏猝死(SCD)为慢性心力衰竭(HF)者的常见并发症,因此预测中重度慢性HF者继发SCD风险尤显重要。既往研究显示.血中可溶性ST2(白介素-1受体家族成员之一)水平升高与急性HF者远期不良预后增加有关。然而关于血中可溶性ST2(sST2)可否预测慢性收缩功能不全性HF者继发SCD风险尚不清楚,现就此进行分析。[第一段]

关键词：慢性心力衰竭收缩功能不全性心脏猝死可溶性 ST2 风险预测白介素-1受体

Tailoring the properties of quantum dot-micropillars by ultrafast optical injection of free charge carriers

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Light(Science & Applications) 2021年第11期10卷 2083-2097页

作者： Emanuel Peinke Tobias Sattler Guilherme M.Torelly Patricia L.Souza Sylvain Perret joel Bleuse Julien Claudon Willem L.Vos Jean-Michel Gerard UniversitéGrenoble Alpes CEAIRIG-PHELIQS“Nanophysique et Semiconducteurs”groupF-38000GrenobleFrance LabSem-CETUC Pontificia Universidade Catolica do Rio de JaneiroRio de Janeiro22451-900Brazil Complex Photonic Systems(COPS) MESA+Institute for NanotechnologyUniversity of TwenteP.O.Box 2177500 AEEnschedethe Netherlands

We review recent studies of cavity switching induced by the optical injection of free carriers in micropillar cavities containing quantum *** the quantum dots as a broadband internal light source and a streak camera as detector,we track the resonance frequencies for a large set of modes with picosecond time *** report a record-fast switch-on time constant(1.5 ps)and observe major transient modifications of the modal structure of the micropillar on the 10 ps time scale:mode crossings are induced by a focused symmetric injection of free carriers,while a lifting of several mode degeneracies is observed when off-axis injection breaks the rotational symmetry of the *** show theoretically and experimentally that cavity switching can be used to tailor the dynamic properties of the coupled QD-cavity *** report the generation of ultrashort spontaneous emission pulses(as short as 6 ps duration)by a collection of frequency-selected QDs in a switched pillar *** pulses display a very small coherence length,attractive for ultrafast speckle-free ***,the control of QD-mode coupling on the 10 ps time scale establishes cavity switching as an appealing resource for quantum photonics.

关键词： lifting injection cavity

Virtual chromoendoscopy in small bowel capsule endoscopy: New light or a cast of shadow?

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World journal of Gastrointestinal Endoscopy 2014年第8期6卷 359-365页

作者： josé Cotter joana Magalh es Francisca Dias de Castro Mara Barbosa Pedro Boal Carvalho Sílvia Leite Maria jo o Moreira Bruno Rosa Gastroenterology Department Centro Hospitalar do Alto Ave 4835-044 Guimar es Portugal Life and Health Sciences Research Institute (ICVS) School of Health Sciences University of Minho 4710-057 Bra-ga Portugal ICVS/3B’s PT Government Associate Laboratory 4710-057 Braga/Guimar es Portugal

AIM: To evaluate whether virtual chromoendoscopy can improve the delineation of small bowel lesions previously detected by conventional white light small bowel capsule endoscopy(SBCE). METHODS: Retrospective single center study. One hundred lesions selected from forty-nine consecutive conventional white light SBCE(SBCE-WL) examinations were included. Lesions were reviewed at three Flexible Spectral Imaging Color Enhancement(FICE) settings and Blue Filter(BF) by two gastroenterologists with ex-perience in SBCE, blinded to each other's findings, whoranked the quality of delineation as better, equivalent or worse than conventional SBCE-WL. Inter-observer percentage of agreement was determined and analyzed with Fleiss Kappa(k) coefficient. Lesions selected for the study included angioectasias(n = 39), ulcers/ero-sions(n = 49) and villous edema/atrophy(n = 12). RESULTS: Overall, the delineation of lesions was im-proved in 77% of cases with FICE 1, 74% with FICE 2, 41% with FICE 3 and 39% with the BF, with a percent-age of agreement between investigators of 89%(k = 0.833), 85%(k = 0.764), 66%(k = 0.486) and 79%(k = 0.593), respectively. FICE 1 improved the delineation of 97.4% of angioectasias, 63.3% of ulcers/erosions and 66.7% of villous edema/atrophy with a percentage of agreement of 97.4%(k = 0.910), 81.6%(k = 0.714) and 91.7%(k = 0.815), respectively. FICE 2 improved the delineation of 97.4% of angioectasias, 57.1% of ulcers/erosions and 66.7% of villous edema/atrophy, with a percentage of agreement of 89.7%(k = 0.802), 79,6%(k = 0.703) and 91.7%(k = 0.815), respectively. FICE 3 improved the delineation of 46.2% of angioecta-sias, 24.5% of ulcers/erosions and none of the cases of villous edema/atrophy, with a percentage of agreement of 53.8% [k = not available(NA)], 75.5%(k = NA) and 66.7%(k = 0.304), respectively. The BF improved the delineation of 15.4% of angioectasias, 61.2% of ulcers/erosions and 25% of villous edema/atrophy, with a per-centage of agreement of 7

关键词： Capsule endoscopy Virtual chromoendoscopy Small bowel enteroscopy Flexible Spectral Imaging Color Enhancement Endoscopy Imaging review

Difficulties Faced by Physicians in the Diagnosis of Endometriosis in the Brazilian Public Health System

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高阶成像参数可改善T2/FLAIR不匹配征预测弥漫性低级别胶质瘤亚型即IDH突变与无1p19q共缺失的价值

Health 2023年第7期

作者： Carla Patrícia Alves Barbosa Tayná Maria Dantas Carozo Calumby Ana Paula Portela Andrade Júlia de Araújo Gomes Maria Renata Suyane Silva de Farias Maria Eduarda Dantas Donald Gabrielly Pinheiro Marinho Antônia Iva Sampaio Bisneta Francisco Expedito Ramos Aguiar Sobrinho Elizabeth Bacha Gabriela Irene Barbosa Débora Irene Barbosa

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国际医学放射学杂志 2020年第2期 249-249页

作者： M.K.Lee J.E.Park Y.jo S.Y.Park S.J.Kim H.S.Kim 冀晓莉 Department of Radiology and Research Institute of Radiology Asan Medical Center University of Ulsan College of Medicine

目的 T2/FLAIR不匹配征与高阶影像学参数结合可提高对弥漫性低级别胶质瘤分子亚型的判断能力。本研究评价表观扩散系数(ADC)、脑血容量(CBV)对T2/FLAIR不匹

关键词： T2/FLAIR CBV ADC AUC 低级别胶质瘤成像参数弥漫性 IDH

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蒙药材黄花铁线莲抗肿瘤活性成分研究

中国保健营养（下半月） 2012年第3期22卷 297-299页

作者：赵·德力格尔呼付明海阿丽莎张屏包保全内蒙古民族大学蒙医药学院

目的:研究黄花铁线莲Clematis intricata干燥带花枝条中的抗肿瘤活性成分。方法:采用海虾幼虫致死实验为抗肿瘤活性追踪测试模型,硅胶、SephadexLH-20和制备型HPLC等色谱手段进行分离纯化,根据波谱数据结合理化性质鉴定化合物结构。结果... 详细信息

目的:研究黄花铁线莲Clematis intricata干燥带花枝条中的抗肿瘤活性成分。方法:采用海虾幼虫致死实验为抗肿瘤活性追踪测试模型,硅胶、SephadexLH-20和制备型HPLC等色谱手段进行分离纯化,根据波谱数据结合理化性质鉴定化合物结构。结果:分离鉴定了7个黄酮,分别为芹菜素(1)、木犀草素-3’-O-β-D-吡喃葡萄糖苷(2)、槲皮素-3-O-β-D-吡喃葡萄糖苷(3)、芦丁(4)、山奈酚-3-O-α-L-吡喃鼠李糖基(1→6)-β-D-吡喃葡萄糖苷(5)、芹菜素-7-O-(6″-E-p-香豆酰基)-β-D-葡萄糖苷(6)、芹菜素-6-C-(6″-E-p-香豆酰基)-β-D-葡萄糖苷(7)。结论:7个化合物均为首次从该植物中分离得到。

关键词：黄花铁线莲蒙药材叶孟类海虾幼虫致死实验化学成分

依从终止高血压膳食疗法与高血压风险:巴西成人健康纵向研究结果

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中华高血压杂志 2020年第10期28卷 952-952页

作者：周卫(译) 袁源(审校) 不详

该文研究高度依从终止高血压膳食(dietary approaches to stop hypertension,DASH)疗法与高血压发病风险降低是否独立相关。参与者包括5632名成年人,在巴西成人健康纵向研究的基线时(2008-2010年)未患高血压,并参加第二次随访(2012-2014... 详细信息

该文研究高度依从终止高血压膳食(dietary approaches to stop hypertension,DASH)疗法与高血压发病风险降低是否独立相关。参与者包括5632名成年人,在巴西成人健康纵向研究的基线时(2008-2010年)未患高血压,并参加第二次随访(2012-2014年)。

关键词：成人健康风险降低终止高血压膳食疗法 hypertension 依从纵向研究高血压发病巴西