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Comparative study of rendezvous techniques in post-liver transplant biliary stricture

World Journal of Gastroenterology 2012年第41期18卷 5957-5964页

作者： Jae Hyuck Chang In seok Lee Ho Jong Chun Jong young choi Seung Kyoo Yoon Dong Goo Kim young Kyoung You Myung-Gyu choi Sok Won Han Department of Internal Medicine College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Radiology College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea Department of Surgery College of MedicineThe Catholic University of KoreaSeoul 137-701South Korea

AIM： To investigate the usefulness of a new rendezvous technique for placing stents using the Kumpe （KMP） catheter in angulated or twisted biliary strictures. METHODS： The rendezvous technique was performed in patients with a biliary stricture after living donor liver transplantation （LDLT） who required the exchange of percutaneous transhepatic biliary drainage catheters for inside stents. The rendezvous technique was performed using a guidewire in 19 patients （guidewire group） and using a KMP catheter in another 19 （KMP catheter group）. We compared the two groups retrospectively. RESULTS： The baseline characteristics did not differ between the groups. The success rate for placing insidestents was 100% in both groups. A KMP catheter was easier to manipulate than a guidewire. The mean pro- cedure time in the KMP catheter group （1012 s, range： 301-2006 s） was shorter than that in the guidewire group （2037 s, range： 251-6758 s, P = 0.022）. The cu- mulative probabilities corresponding to the procedure time of the two groups were significantly different （P = 0.008）. The factors related to procedure time were the rendezvous technique method, the number of inside stents, the operator, and balloon dilation of the stric- ture （P 〈 0.05）. In a multivariate analysis, the rendez- vous technique method was the only significant factor related to procedure time （P = 0.010）. The procedural complications observed included one case of mild acute pancreatitis and one case of acute cholangitis in the guidewire group, and two cases of mild acute pancre- atitis in the KMP catheter group. CONCLUSION： The rendezvous technique involving use of the KIVlp catheter was a fast and safe method for placing inside stents in patients with LDLT biliary stric- ture that represents a viable alternative to the guide- wire rendezvous technique,

关键词： Rendezvous Biliary stricture Liver trans-plantation Endoscopic retrograde cholangiography Percutaneous transhepatic biliary drainage

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A Self‑Regenerable Fiber Sloughing Its Heavy Metal Skin for Ultrahigh Separation Capability

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Advanced Fiber Materials 2023年第6期5卷 2127-2142页

作者： youngkyun Jung Ji Su Park Kyung‑Won Jung young Gun Ko Jae‑Woo choi Center for Water Cycle Research Korea Institute of Science and TechnologySeoul 02792Republic of Korea Center for Bionics Korea Institute of Science and TechnologySeoul 02792Republic of Korea Department of Chemical Engineering and Materials Science Sangmyung UniversitySeoul 03016Republic of Korea Division of Energy&Environment Technology KIST SchoolKorea University of Science and Technology(UST)Seoul 02792Republic of Korea

Developing efficient separation materials for recovering metal resources from aqueous environments is crucial for the sustainable water–food–energy nexus,which addresses the interdependence between energy production,water production,and energy *** material-based separation processes have demonstrated outstanding ***,electric energy and chemicals are used to frequently replace the separation materials used in such processes owing to their short life *** study presents a methodology for designing the self-regenerable fiber(SRF)according to the types of metals through a self-regeneration *** SRF can semi-permanently recover the metal resources from water through a repetitive adsorption–crystallization–detachment process of metal ions on its *** ionic metal resources are adsorbed and crystallized with the counter-anions on the SRF ***,the metal crystals are self-detached from the SRF surface by the collision between the crystals and curvature and non-sticky surface of the ***,a module containing the SRF maintains its metal recovery capability even during continuous injection of the metal solution without its *** findings highlight the significance of interfacial engineering and further guide the rational design of energy/environmentally friendly resource recovery modules.

关键词： Self-regeneration model Self-regenerable fiber Semi-permanent adsorption capability Metal crystal growth-detachment

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Vitisin B inhibits influenza A virus replication by multi-targeting neuraminidase and virusinduced oxidative stress

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Acta Pharmaceutica Sinica B 2023年第1期13卷 174-191页

作者： Eun-Bin Kwon Wei Li young Soo Kim Buyun Kim Hwan-Suck Chung younghoon Go Hyun-Jeong Ko Jae-Hyoung Song young Ho Kim Chun Whan choi Jang-Gi choi Korean Medicine(KM)Application Center Korea Institute of Oriental MedicineDaegu 41062Republic of Korea College of Pharmacy Chungnam National UniversityDaejeon 34134Republic of Korea Natural Product Research Team BiocenterGyeonggido Business and Science AcceleratorGyeonggi-Do 16229Republic of Korea Laboratory of Microbiology and Immunology College of PharmacyKangwon National UniversityChuncheon 24341Republic of Korea

The development of drug-resistant influenza and new pathogenic virus strains underscores the need for antiviral ***,neuraminidase(NA)inhibitors are commonly used antiviral drugs approved by the US Food and Drug Administration(FDA)for the prevention and treatment of ***,we show that vitisin B(VB)inhibits NA activity and suppresses H1N1 viral replication in MDCK and A549 *** oxygen species(ROS),which frequently occur during viral infection,increase virus replication by activating the NF-κB signaling pathway,downmodulating glucose-6-phosphate dehydrogenase(G6PD)expression,and decreasing the expression of nuclear factor erythroid2-related factor 2(Nrf2)antioxidant response *** decreased virus-induced ROS generation by increasing G6PD expression and Nrf2 activity,and inhibiting NF-κB translocation to the nucleus through IKK *** addition,VB reduced body weight loss,increased survival,decreased viral replication and the inflammatory response in the lungs of influenza A virus(IAV)-infected *** together,our results indicate that VB is a promising therapeutic candidate against IAV infection,complements existing drug limitations targeting viral *** modulated the intracellular ROS by G6PD,Nrf2 antioxidant response pathway,and NF-κB signaling *** results demonstrate the feasibility of a multi-targeting drug strategy,providing new approaches for drug discovery against IAV infection.

关键词： Influenza Vitisin B Vitis vinifera L. Neuraminidase Reactive oxygen species NF-κB Multi-targeting Nrf2 G6PD

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Plant-derived nanovesicles: Current understanding and applications for cancer therapy

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Bioactive Materials 2023年第4期22卷 365-383页

作者： Ngoc Phung Ly Hwa Seung Han Myungsuk Kim Jae Hyung Park Ki young choi Natural Product Informatics Research Center Korea Institute of Science and Technology(KIST)Gangneung25451Republic of Korea Division of Bio-Medical Science and Technology KIST SchoolUniversity of Science and Technology(UST)Seoul02792Republic of Korea School of Chemical Engineering College of EngineeringSungkyunkwan UniversitySuwon16419Republic of Korea Department of Health Sciences and Technology SAIHSTSungkyunkwan UniversitySeoul06351Republic of Korea Biomedical Institute for Convergence at SKKU Sungkyunkwan UniversitySuwon16419Republic of Korea

Plant-derived vesicles(PDVs)are membranous structures that originate from plant cells and are responsible for multiple physiological and pathological *** the last decade,PDVs have gained much attention for their involvement in different biological processes,including intercellular communication and defense response,and recent scientific evidence has opened a new avenue for their applications in cancer ***,much remains unknown about these vesicles,and current research remains *** review aims to provide a comprehensive introduction to PDVs,from their biological characteristics to purification methods,and to summarize the status of their potential development for cancer therapy.

关键词： Plant-derived vesicles Extracellular vesicles Cancer therapy Anti-cancer Drug delivery

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Blood flow Interpretation in Femoral Pseudoaneurysm

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Journal of Thermal Science 2013年第3期22卷 229-233页

作者： Sang-Ho Suh young Ho choi Hyoung-Ho Kim Min-Gyu Jeon Deog-Hee Doh Dept. of Mechanical Engineering Soongsil University Department of Radiology Seoul Nat'l University Boramae Hospital Graduate School Korea Maritime Univ. Division of Mechanical and Energy Systems Engineering Korea Maritime University

A femoral artery pseudoaneurysm is one complication of vascular intervention, and the incidence is increasing. Early management is then needed to avoid potential dangers from it. It differs from a true aneurysm in that it doesn't include any component of the vascular wall, and is not studied as much as a true aneurysm. Here, a model of a femoral pseudoaneurysm was made and a Computational Fluid Dynamics(CFD) simulation was verified with PIV experiment. Afterwards, a CFD simulation with two different models was performed to look for any findings which may help in developing new treatment methods.

关键词： Femoral Artery, Pseudoaneurysm, Numerical and PIV experimental Interpretation

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Comparison of the Bright Band Characteristics Measured by Micro Rain Radar (MRR) at a Mountain and a Coastal Site in South Korea

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Advances in Atmospheric Sciences 2009年第2期26卷 211-221页

作者： Joo-Wan CHA Ki-Ho CHANG Seong Soo YUM young-Jean choi Department of Atmospheric Sciences Yonsei University Global Environment System Research Laboratory NIMR/KMA

Data from a long term measurement of Micro Rain Radar （MRR） at a mountain site （Daegwallyeong, DG, one year period of 2005） and a coastal site （Haenam, HN, three years 2004-2006） in South Korea were analyzed to compare the MRR measured bright band characteristics of stratiform precipitation at the two sites. On average, the bright band was somewhat thicker and the sharpness （average gradient of reflectivity above and below the reflectivity peak） was slightly weaker at DG, compared to those values at HN. The peak reflectivity itself was twice as strong and the relative location of the peak reflectivity within the bright band was higher at HN than at DG. Importantly, the variability of these values was much larger at HN than at DG. The key parameter to cause these differences is suggested to be the difference of the snow particle densities at the two sites, which is related to the degree of riming. Therefore, it is speculated that the cloud microphysical processes at HN may have varied significantly from un-rimed snow growth, producing low density snow particles, to the riming of higher density particles, while snow particle growth at DG was more consistently affected by the riming process, and therefore high density snow particles. Forced uplifting of cloudy air over the mountain area around DG might have resulted in an orographic supercooling effect that led to the enhanced riming of supercooled cloud drops.

关键词： Micro Rain Radar bright band thickness and sharpness cloud microphysical processes local characteristics

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Docurity: A New Cryptographic Primitive for Collaborative Cloud Systems

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Intelligent Automation & Soft Computing 2023年第6期36卷 3725-3742页

作者： Byeori Kim Minseong choi Taek-young Youn Jeong Hyun Yi Haehyun Cho Soongsil University Seoul06978Korea Dankook University Yongin16890Korea

Recently,there has been a sudden shift from using traditional office applications to the collaborative cloud-based office suite such as Microsoft Office *** cloud-based systems allow users to work together on the same docu-ment stored in a cloud server at once,by which users can effectively collaborate with each ***,there are security concerns unsolved in using cloud *** of the major concerns is the security of data stored in cloud ser-vers,which comes from the fact that data that multiple users are working together cannot be stored in encrypted form because of the dynamic characteristic of cloud *** this paper,we propose a novel mode of operation,DL-ECB,for AES by which we can modify,insert,and delete the ciphertext based on changes in ***,we can use encrypted data in collaborative cloud-based *** demonstrate that the DL-ECB mode can preserve the confidential-ity,integrity,and auditability of data used in collaborative cloud systems from adversaries,we implement and evaluate the prototype of the DL-ECB mode.

关键词： Cloud collaboration mode of operation auditability of ciphertext

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Sweet food improves chronic stress-induced irritable bowel syndrome-like symptoms in rats

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World Journal of Gastroenterology 2014年第9期20卷 2365-2373页

作者： Sang-Gyun Rho Yong Sung Kim Suck Chei choi Moon young Lee Department of Emergency Medical Services Sunmoon University Chungnam Asan 336-708 South Korea Department of Gastroenterology and Wonkwang Digestive Disease Research Institute Wonkwang University Sanbon Hospital Gyeonggi Gunpo 435-040 South Korea Department of Gastroenterology and Wonkwang Digestive Disease Research Institute School of MedicineWonkwang University Jeonbuk Iksan 570-974 South Korea Department of Physiology and Institute of Wonkwang Medical Science and Wonkwang Digestive Disease Research Institute School of Medicine Wonkwang UniversityJeonbuk Iksan 570-749 South Korea

AIM: To investigate whether palatable sweet foods have a beneficial effect on chronic stress-induced colonic motility and inflammatory cytokines.

关键词： Irritable bowel syndrome Colon Stress Adrenal hormones Cytokines Rat

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Restoration of an Inner-City Stream and Its Impact on Air Temperature and Humidity Based on Long-Term Monitoring Data

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Advances in Atmospheric Sciences 2009年第2期26卷 283-292页

作者： Kyu Rang KIM Tae Heon KWON Yeon-Hee KIM Hae-Jung KOO Byoung-Cheol choi Chee-young choi Applied Meteorology Research Laboratory National Institute of Meteorological Research Korea Meteorological Administration Applied Meteorology Research Laboratory National Institute of Meteorological ResearchKorea Meteorological Administration

Spatiotemporal changes in air temperature and humidity associated with the restoration of an innercity stream in Seoul, Korea, are investigated based on long-term monitoring data. The Cheonggye stream, covered under a concrete structure for 46 years, was restored in 2005 and runs 5.8 km eastward through a central region of Seoul. Long-term monitoring of the air temperature and relative humidity was made along the stream throughout the restoration and across the stream after the restoration. The area along the stream had a higher air temperature than the entire metropolitan area. The temperature anomaly between the monitoring area and the surrounding metropolitan area was 0.13℃ lower on average at the center of the stream after the restoration. The stream＇s effect on the air temperature was also evident in the temperature distribution along a street traversing the stream. The relative and specific humidities were increased due to the restoration. The restored stream modified the nearby urban climate in the opposite direction compared to urbanization. The results could be used as a model case in mitigating urban climate by a stream in future urban planning practices.

关键词： urban heat island stream restoration land-use vegetation Cheonggye stream

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Effect of incision types for Artisan phakic intraocular lens implantation on ocular higher order aberrations

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International Journal of Ophthalmology(English edition) 2016年第12期9卷 1785-1789页

作者： young Min Park Bong Joon choi Jong Soo Lee Department of Ophthalmology Gyeongsang National University School of Medicine Gyeongsang National University Changwon Hospital 11 Samjeongja-ro Seongsan-gu Changwon-si Gyeongsangnam-do 51472 Korea Lee Eye Clinic Pusan 47524 Korea Department of Ophthalmology School of Medicine Pusan National University and Medical Research Institute Pusan National University Hospital Pusan 602-739 Korea

AIM： To evaluate the effect of incision types for Artisan phakic intraocular lens （PIOL） implantation on ocular higher-order aberrations （HOAs）.METHODS： A retrospective review was conducted of the patients who had undergone Artisan PIOL implantation for the correction of myopia and followed up for at least 6mo. Patients are classified into 2 groups considering the incision type： cornea group with patients undergone clear corneal incision; sclera group with patients undergone sclera tunnel incision. All patients with postoperative astigmatism of under 1 diopter （D） were included to minimize the effect of residual astigmatism on postoperative HOAs. Visual acuity, special equivalents, astigmatism, predictability （±1 D from target refraction）, HOAs （coma, trefoil, spherical aberration）, and corneal endothelial counts were analyzed preoperatively and 6mo ***： At the postoperative 6mo, all patients of both groups achieved uncorrected visual acuity of 16/20 or better, and significantly decreased the spherical equivalents compared with preoperative values. The predictability of refractive correction was 96% in the former, and 94% in the latter. Unlike the sclera group, preoperative astigmatism decreased significantly in cornea group at postoperative 6mo. The HOAs increased significantly at postoperative 6mo compared to the preoperative values in both groups, and the root mean square （RMS） total and trefoil wavefront aberration of cornea group were significantly higher than those of sclera ***： Although corneal incision significantly reduces preexisting astigmatism, the postoperative 6mo of total RMS and trefoil aberration change may deteriorate the visual quality after Artisan PIOL implantation.

关键词： Artisan astigmatism higher-order aberrations incision phakic intraocular lens

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