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Cryptogenic organizing pneumonia associated with pregnancy:A case report

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World Journal of Clinical Cases 2022年第6期10卷 1946-1951页

作者： young Joo lee young Sun Kim Department of Obstetrics and Gynecology Kyung Hee University Medical CenterSeoul 02447South Korea

BACKGROUND Cryptogenic organizing pneumonia(COP),formerly known as bronchiolitis obliterans organizing pneumonia,is an extremely rare disease in *** this case,we report on COP diagnosed in recurrent pneumonia that does not respond to antibiotics in pregnant *** SUMMARY A 35-year-old woman with no prior lung disease presented with concerns of chest pain with cough,sputum,dyspnea,and mild fever at 11 wk’*** was diagnosed with community-acquired pneumonia and treated with antibiotics;her symptoms improved *** weeks after discharge,she was readmitted with aggravated *** computed tomography demonstrated multifocal patchy airspace consolidation and ground-glass opacities at the basal segments of the right lower lobe,at the lateral basal segment of the lower lobe,and at the lingular segment of the left upper *** lavage revealed an increased lymphocyte count and a decreased CD4/CD8 ***(0.5 mg/kg/d)was administered for 10 d after the second *** improved after 3 d of steroid treatment and other symptoms improved on the 5th day of steroid ***-delivery transbronchial lung biopsy further revealed the presence of granulation tissue with fibroblasts in smallbronchiole *** This case suggests that it is important to differentiate COP from atypical pneumonia in the deteriorated condition despite antibiotic treatment.

关键词： Antibiotics Bronchiolitis obliterans organizing pneumonia Corticosteroid Cryptogenic organizing pneumonia Pregnancy Case report

A Wireless Sensor Network Platform for Elderly Persons at Home

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稀有金属材料与工程 2006年第A3期35卷 95-99页

作者： young-Dong lee Dae-Seok lee Wan-young Chung Risto Myllylae Dept of Computer Network Eng Graduate School of SoftwareDongseo UniversityBusan 617-716Korea Division of Computer & Information Eng Dongseo UniversityBusan 617-716Korea Dept of Electrical and Information Engineering University of OuluLinnanmaa 90570 OuluFinland

A small size ubiquitous healthcare system for the home care of elderly persons was designed and *** system comprised a wireless sensor network node,base station and server computer for the continuous monitoring of ECG *** data,an important vital sign that is commonly used in clinical and trauma care,were displayed on a graphical user interface (GUI) by transferring the data to a PDA or a terminal *** data transfer was accomplished through a base-station connected to a server computer using TCP/***-time ECG data of elderly persons or patients,as well as historical data,can also be retrieved and played back to assist the *** ubiquitous healthcare system presented in this study can effectively reduce social medical expenses,which will increase greatly in the aging society.

关键词： wireless sensor network ubiquitous healthcare ECG TinyOS platform

Feasibility Study of R134a/R404a Cascade Heat Pump Cycle in Heat Pump Dryers with Electrical Heaters at Low Temperatures

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Journal of Thermal Science 2015年第5期24卷 463-467页

作者： Ji Woo Jeong young Lim lee Dept. of Mechanical Engineering Kongju National University Dept. of Mechanical and Automotive Engineering Kongju National University

Heat pump cycles have been widely applied to dryers for their high efficiency. However, low–efficiency electrical heaters are often used during early drying stage for frozen foods or winter since a standard heat pump cycle cannot operate at low temperature. This study introduced cascade heat pumps replacing electrical heaters to improve dryer performance at low temperatures. Experiments were performed to examine changes in performance of the cascade heat pump dryers in relation to ambient temperature, low-stage cycle mass flow rate, and high-stage cycle mass flow rate. The results showed a significant improvement in low-temperature dryer performance with the introduction of cascade heat pump cycles.

关键词： Cascade cycle R134a/R404a Heat pump dryer COP Energy efficiency

Evaluation of ring surfaces with several coatings for friction,wear and scuffing life

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中国有色金属学会会刊：英文版 2009年第4期19卷 992-996页

作者： Dae-Hyun CHO young-Ze lee School of Mechanical Engineering Sungkyunkwan University

Friction and wear of the sliding components in an automobile cause an increase in both fuel consumption and *** engine components involved with sliding contact are all susceptible to scuffing failure at some points during their operating ***,it is important to evaluate the effects of various surface coatings on the tribological characteristics of the piston ring and cylinder block surface of a diesel *** and scuffing tests were conducted using a friction and wear measurement of the piston ring and cylinder block in a low friction diesel *** frictional forces,wear amounts and cycles to scuffing in the boundary lubricated sliding condition were measured using the reciprocating wear *** tester used a piece of the cylinder block as the reciprocating specimen and a segment of the piston ring material as the fixed *** coatings on the ring specimen were used,such as DLC,TiN,Cr-ceramic and TiAlN,in order to improve the tribological characteristics of the *** coefficients of friction were monitored during the tests,and the wear volumes of the piston ring surfaces with various coatings were *** results show that the DLC coating exhibits better tribological properties than the other *** graphite structure of this coating is responsible for the low friction and wear of the DLC *** TiN and DLC coatings show better scuffing resistance than the other *** TiN and Cr-ceramic coated rings show good wear resistance and high friction.

关键词：涂层表面摩擦评价生活划伤磨损

Macrophage activation syndrome in children with Kawasaki disease: diagnostic and therapeutic approaches

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World Journal of Pediatrics 2020年第6期16卷 566-574页

作者： Seung Beom Han Soo-young lee Department of Pediatrics Daejeon St.Mary's Hospital.College of MedicineThe Catholic University of Korea64 Daeheung-ro.Jung-guDaejeon 34943Republic of Korea Department of Pediatrics.Bucheon St.Mary's Hospital College of MedicineThe Catholic University of Korea327 Sosa-roWonmi-gu.Bucheon 14647Republic of Korea

Background Macrophage activation syndrome(MAS)is a rare,life-threatening complication of Kawasaki disease(KD).Early recognition and treatment of MAS are very important,but sometimes it is difficult to distinguish MAS from a severe form of *** sources A PubMed search was performed in Clinical Queries using the key terms“macrophage activation syndrome or secondary hemophagocytic lymphohistiocytosis(HLH)”and“Kawasaki disease”.Results KD patients with MAS show high intravenous immunoglobulin(IVIG)resistance and coronary *** is also as high as MAS in other *** fever greater than 10 days is highly associated with development of MAS in *** is observed in more than two-thirds of KD patients with *** is often the earliest laboratory finding of *** is highly specific and sensitive for detecting MAS in KD;so,ferritin levels should be checked if there are unexplained clinical exacerbations in KD *** the under-recognition of MAS in KD,it is prudent to consider resistant KD as occult/subclinical *** KD patients with MAS have good outcomes on immune ***,if KD patients fulfill the HLH-2004 diagnostic criteria,they may undergo longer and more intensive treatment than *** The possible existence of MAS should be taken into account when a KD patient shows persistent fever,splenomegaly,thrombocytopenia,hyperferritinemia,or IVIG *** under-diagnosis of MAS in patients with KD is an important issue to be ***,however,there is a possibility of over-treatment of MAS in patients with KD.

关键词： Macrophage activation syndrome Kawasaki disease Children

Remote induction of in situ hydrogelation in a deep tissue,using an alternating magnetic field and superparamagnetic nanoparticles

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Nano Research 2018年第11期11卷 5997-6009页

作者： Hwangjae lee Guru Karthikeyan Thirunavukkarasu Semin Kim Jae young lee School of Materials Science and Engineering Gwangju Institute of Science and Technology Gwongju 51005 Republic of Korea Department of Biomedical Science and Engineering Gwangju Institute of Science and Technology Gwangju 61005 Repubfic of Korea

In situ hydrogelation systems, such as transdermal polymerization, allow for external control over the gelation processes in a minimally invasive way. Recently, a novel system consisting of near-infrared (NIR) light and plasmonic nanomaterials was demonstrated to cause in vivo transdermal gelation. However, NIR light is not sufficient for gelation induction in deep tissues owing to its limited penetration into tissues. To overcome this problem, here we developed an alternating magnetic field (AMF)-inducible hydrogelation system with superparamagnetic iron oxide nanoparticles (SPIONs), by which a deep-tissue–penetrating AMF can induce heat generation in the SPIONs and temperature elevation (≥ 43 °C), leading to initiation of thermal polymerization of poly(ethylene glycol) diacrylate. The feasibility of our AMF-inducible hydrogelation was successfully demonstrated using thick porcine muscle tissues (> 2 cm), whereas the NIR light–based hydrogelation system could induce gelation only in tissues thinner than several millimeters. Cell viability assays indicated cytocompatibility of the AMF-inducible hydrogelation for cell encapsulation and delivery. In vivo hydrogelation in rat muscle tissues further validated in situ hydrogelation in deep muscle tissues of a living animal. This AMF-inducible hydrogelation system may overcome the conventional problems of depth limitation and should extend the applicable area of on-demand injectable hydrogel systems for tissue engineering and drug delivery applications.

关键词： hydrogelation alternating magnetic field superparamagnetic nanoparticles hydrogel tissue engineering cell delivery

Transparent Supercapacitors: From Optical Theories to Optoelectronics Applications

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Energy & Environmental Materials 2020年第3期3卷 265-285页

作者： Sang-Woo Kim Sang-young lee Department of Energy Engineering School of Energy and Chemical EngineeringUlsan National Institute of Science and Technology(UNIST)Ulsan 689-798Korea

The ever-increasing demand for smart optoelectronics spurs the relentless pursuit of transparent wireless devices as a game-changing technology that can provide unseen visual information behind the *** enable successful operation of the transparent wireless devices,their power sources should be highly transparent in addition to acquiring reliable electrochemical *** various transparent power sources,supercapacitors(SCs)have been extensively investigated as a promising candidate due to their exceptional cyclability,power capability,material diversity,and scalable/low-cost ***,we describe current status and challenges of transparent SCs,with a focus on their core materials,performance advancements,and integration with application devices.A special attention is devoted to transparent conductive electrodes(TCEs)which act as a keyenabling component in the transparent *** on fundamental understanding of optical theories and operating principles of transparent materials,we comprehensively discuss materials chemistry,structural design,and fabrication techniques of *** addition,noteworthy progresses of transparent SCs are briefly overviewed in terms of their architectural design,opto-electrochemical performance,flexibility,form factors,and integration compatibility with transparent flexible/wearable devices of ***,development direction and outlook of transparent SCs are explored along with their viable roles in future application fields.

关键词： energy storage flexibility optoelectronics transparent conductive electrodes transparent supercapacitors

Intestinal microbiota in pathophysiology and management of irritable bowel syndrome

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World Journal of Gastroenterology 2014年第27期20卷 8886-8897页

作者： Kang Nyeong lee Oh young lee Department of Internal Medicine Hanyang University College of Medicine

Irritable bowel syndrome (IBS) is a functional bowel disorder without any structural or metabolic abnormalities that sufficiently explain the symptoms, which include abdominal pain and discomfort, and bowel habit changes such as diarrhea and constipation. Its pathogenesis is multifactorial: visceral hypersensitivity, dysmotility, psychosocial factors, genetic or environmental factors, dysregulation of the brain-gut axis, and altered intestinal microbiota have all been proposed as possible causes. The human intestinal microbiota are composed of more than 1000 different bacterial species and 1014 cells, and are essential for the development, function, and homeostasis of the intestine, and for individual health. The putative mechanisms that explain the role of microbiota in the development of IBS include altered composition or metabolic activity of the microbiota, mucosal immune activation and inflammation, increased intestinal permeability and impaired mucosal barrier function, sensory-motor disturbances provoked by the microbiota, and a disturbed gut-microbiota-brain axis. Therefore, modulation of the intestinal microbiota through dietary changes, and use of antibiotics, probiotics, and anti-inflammatory agents has been suggested as strategies for managing IBS symptoms. This review summarizes and discusses the accumulating evidence that intestinal microbiota play a role in the pathophysiology and management of IBS.

关键词： Immunity Irritable bowel syndrome Microbiota Permeability Probiotics

Friction and wear of textured surfaces produced by 3D printing

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Science China(Technological Sciences) 2017年第9期60卷 1400-1406页

作者： HONG yi ZHANG Peng lee Kwang-Hee lee Chul-Hee Department of Mechanical Engineering Inha University Incheon 402-751 Korea

Surface texture patterns have great potential for improving tribological performance in terms of reducing friction and wear. The most common methods for surface texatring are laser and injection molding. The 3D printing method is also used to build parts, patterns, and molds that feature fine details for a wide range of applications because texture manufacturing by 3D printing is faster, more flexible, and less expensive than traditional techniques. To date, there has been no research on textured surfaces produced by 3D printing. Therefore, a new fabrication method using 3D printing to improve friction and wear properties is a topic worth exploring. In this study, a reciprocating friction tester was used to evaluate the friction and wear properties of different surface textures produced by 3D printing. The surface of specimens was examined by electron microscope and scanning electron microscope before and after the test. The results show that surface texturing can be applied to 3D printed parts to improve their friction and wear performance.

关键词： three-dimensional (3D) printing texture friction wear