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Incomplete distal renal tubular acidosis uncovered during pregnancy:A case report

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世界临床病例杂志 2023年第25期11卷 5988-5993页

作者： Eun young Seong Da woon Kim Hyo Jin Kim Harin Rhee Sang Heon Song Department of Internal Medicine Biomedical Research InstitutePusan National University HospitalBusan 49241South Korea Department of Internal Medicine School of MedicinePusan National UniversityYangsan-si 50612Gyeongsangnam-doSouth Korea Department of Internal Medicine Pusan National University School of MedicineBusan 49241South Korea

BACKGROUND Renal tubular acidosis(RTA)is a renal cause of non-anion-gap metabolic acidosis characterized by low urinary ammonia *** condition has a low prevalence,and various congenital and acquired *** date,only a few cases of idiopathic RTA uncovered during pregnancy have been *** SUMMARY A previously healthy 32-year-old Korean woman at 30 wk of gestation was admitted to Pusan National University Hospital with preterm *** admission,the patient presented with hypokalemia,non-anion-gap metabolic acidosis,and *** RTA was diagnosed based on laboratory blood and urine findings and imaging *** tests,including next-generation gene sequencing panels for nephropathy,were performed to determine the etiology of the disease,which indicated that it was *** patient received sodium bicarbonate and potassium chloride *** 3 wk,she delivered a baby who was subsequently diagnosed with corpus callosum agenesis and *** regular follow-ups for 6 mo postpartum,her hypokalemia and metabolic acidosis were gradually resolved,and medications eventually *** Herein we describe a case of idiopathic distal RTA discovered during *** and metabolic acidosis resolved spontaneously after delivery.

关键词： Renal tubular acidosis Pregnancy Hypokalemia Sodium bicarbonate Case report

Nanocomposite quasi-solid-state electrolyte for high-safety lithium batteries

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Nano Research 2017年第9期10卷 3092-3102页

作者： Hyunji Choi Hyun Woo Kim Jae-Kwang Kim young Jun lim youngsik Kim Jou-Hyeon Ahn School of Energy & Chemical Engineering Ulsan National Institute of Science and Technology (UNIST) Ulsan 689-798 Republic of Korea Department of Solar & Energy Engineering Cheongju University Cheongju Chungbuk 28503 Republic of Korea School of Energy & Chemical Engineering and Research Institute for Green Energy Convergence Technology Gyeongsang National University 900 Gajwa-dong Jinju 660-70 I Republic of Korea

Rechargeable lithium batteries are attractive power sources for electronic devices and are being aggressively developed for vehicular use. Nevertheless, problems with their safety and reliability must be solved for the large-scale use of lithium batteries in transportation and grid-storage applications. In this study, a unique hybrid solid-state electrolyte composed of an ionic liquid electrolyte (LiTFSI/Pyr14TFSI) and BaTiO3 nanosize ceramic particles was prepared without a polymer. The electrolyte exhibited high thermal stability, a wide electrochemical window, good ionic conductivity of 1.3 × 10−3 S·cm−1 at 30 °C, and a remarkably high lithium-ion transference number of 0.35. The solid-state LiFePO4 cell exhibited the best electrochemical properties among the reported solid-state batteries, along with a reasonable rate capability. Li/LiCoO2 cells prepared using this nanocomposite solid electrolyte exhibited high performance at both room temperature and a high temperature, confirming their potential as lithium batteries with enhanced safety and a wide range of operating temperatures.

关键词： nanocomposition solidified ionic liquid shell charge space safety lithium battery

Effects of Mg Enhancement and Heat Treatment on Microstructures and Tensile Properties of Al2Ca-Added ADC12 Die Casting Alloys

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Journal of Materials Science & Technology 2016年第10期32卷 1043-1048页

作者： Gil-Yong Yeom Hyun Kyu lim Shae K.Kim Soong-Keun Hyun young-Ok Yoon Korea Institute of Industrial Technology lncheon 406-840 South Korea Department of Materials Science and Engineering Inha University lncheon 402-751 South Korea

The effects of Mg enhancement and heat treatment on the microstructures and tensile properties of Al_2Ca-added ADC12 die casting alloys were investigated. 0.3% and 0.5% Mg in the form of a master alloy including a trace amount of Al_2Ca were added to conventional ADC12（383 and AlSi10Cu2Fe） alloy with an initial Mg-content of 0.3% to increase the Mg content to 0.6% and 0.8%, respectively. To avoid heat treatmentinduced surface blisters, shortened solution treatment for 15 min at 490 ℃ and artificial aging for 6 h at 150 ℃ was undertaken. The results show that a 10% improvement in the shape factor of eutectic Si particles was achieved for Al_2Ca-added ADC12 with 0.8% Mg compared to the conventional ADC12 in the as-aged condition. Al_2Ca-added ADC12 with 0.8% Mg exhibited a yield strength of 289 MPa, a tensile strength of 407 MPa, and an elongation of 4.22%.

关键词： Al2Ca ADC12 alloy Heat treatment Die casting Inclusion

Polyaniline and multi-walled carbon nanotube composite electrode for rechargeable battery

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中国有色金属学会会刊：英文版 2012年第S3期22卷 717-721页

作者： Yu-Jeong lim Min-young PARK Sang-Keol LEE Won-Ki LEE Nam-Ju JO Department of Polymer Science & Engineering Pusan National University Hankook Tire Co.Ltd. Department of Polymer Engineering Pukyong National University

The multi-walled carbon nanotube was introduced into the polymer matrix (PANI) to improve the electric conductivity as well as mechanical properties of the original polymer ***/multi-walled carbon nanotube (MWCNT) composites were synthesized via ex-situ and in-situ polymerization to improve their electrical *** the DC conductivities of PANI/MWCNT according to content and diameter of MWCNT were measured by four-point *** highest electric conductivity of PANI/MWCNT composite is 20 S/cm when 0.3% (mass fraction) MWCNTs with 10 nm in diameter and 15 μm in length are added in composite.

关键词： polymer electrode electric conductivity multi-walled carbon nanotube conducting polymer

Effect of ZnO Electrodeposited on Carbon Film and Decorated with Metal Nanoparticles for Solar Hydrogen Production

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Journal of Materials Science & Technology 2016年第10期32卷 1059-1065页

作者： young Kwang Kim Hye-Jin Seo Soonhyun Kim Sung-Ho Hwang Hyunwoong Park Sang Kyoo lim Division of Nano and Energy Convergence Research Daegu Gyeongbuk Institute of Science and Technology (DGIST) School of Energy Engineering Kyungpook National University

In this study, we prepared horn-like ZnO structures on carbon films（ZnO/CF） by electrodeposition and decorated the ZnO horns with different metals（Ag, Au, and Pt） via photodeposition（M-ZnO/CF）. Using M-ZnO/CF as photocatalysts, we examined ways to enhance solar hydrogen production from various points of view, such as modifying the intrinsic physical properties and thermodynamics of the materials, and varying the chemical environment during M-ZnO/CF fabrication. In particular, we focused on the effects of the carbon film and metals in M-ZnO/CF hybrid photocatalysts on solar hydrogen production. The type of metal nanoparticles is an important factor in solar hydrogen production because the deposition rate and electrical conductivity of each metal affect the proton-water reduction ability.

关键词： Solar hydrogen production ZnO horn Carbon film Metal nanoparticle Electrodeposition

Phytoglycoprotein isolated from Dioscorea batatas Decne promotes intestinal epithelial wound healing

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Chinese Journal of Natural Medicines 2020年第10期18卷 738-748页

作者： KIM Ji-Yun LEE young-Min PARK Jong-Pil lim Kye-Taek LEE Sei-Jung Department of Pharmaceutical Engineering Daegu Haany UniversityGyeongsan 38610Republic of Korea Department of Food Science and Technology Chung-Ang UniversityAnseong 17546Republic of Korea Division of Animal Science Chonnam National UniversityGwangju61186Republic of Korea

Dioscorea batatas Decne(DBD)has been used to heal various illnesses of the kidney and intestine as an herbal medicine in *** a source of therapeutic agents,many glycoproteins have been isolated from mushrooms and plants,but the functional role of glycoprotein in intestinal epithelial wound healing has not been understood *** the present study,we investigated the wound healing potentials of the 30 kDa glycoprotein(DBD glycoprotein)isolated from DBD in human intestinal epithelial(INT-407)*** found that DBD glycoprotein(100μg·mL^-1)significantly increased the motility of INT-407 cells for 24 h by activating protein kinase C(PKC).DBD glycoprotein stimulated the activation of p38 mitogen-activated protein kinase(MAPK),which is responsible for the phosphorylation of NF-κB inhibitorα(IκBα).DBD glycoprotein increased the level of profilin-1(PFN1),α-actinin and F-actin expression via activation of transcription factor,nuclear factor-kappa B(NF-κB)during its promotion of cell *** mouse colitis was induced by adding dextran sulfate sodium(DSS)to the drinking water at a concentration of 4%(W/V)for 7 *** figured out that administration of DBD glycoprotein(10 and 20 mg·kg-1)lowers the levels of disease activity index and histological inflammation in DSS-treated ICR *** this regard,we suggest that DBD glycoprotein has ability to promote the F-actin-related migration signaling events via activation of PKC and NF-κB in intestinal epithelial cells and prevent inflammatory bowel disease.

关键词： Cell migration Dioscorea batatas Decne(DBD)glycoprotein Intestinal epithelial cells p38 MAPK F-actin Mouse colitis

Visual quality assessment after presbyopic laser in-situ keratomileusis

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International Journal of Ophthalmology(English edition) 2018年第3期11卷 462-469页

作者： Dong Hui lim Eui-Sang Chung Myoung Joon Kim Tae-young Chung Department of Ophthalmology Samsung Medical Center Sungkyunkwan University School of Medicine Department of Preventive Medicine Graduate School the Catholic University of Korea Department of Ophthalmology University of Ulsan College of MedicineAsan Medical Center

AIM： To assess visual quality after presbyopia correction using an aspheric ablation profile and a micro-monovision protocol. METHODS： This is a retrospective interventional study. Fifty-four eyes of 27 patients （mean age, 50.2±7.5y） who underwent presbyopia correction with an aspheric micro-monovision protocol were enrolled. The values of modulation transfer function （MTF） cutoff frequency, Strehl ratio, objective scattering index （OSI） and accommodation range were quantitatively assessed using the HD analyzer. Preoperative and postoperative contrast sensitivity （CS） at far （2.5 m） and near （40 cm） distance and higher-order aberrations （HOAs） were analyzed. Subjective visual satisfaction was evaluated by self-reported questionnaire regarding optical visual symptoms. RESULTS： One year after presbyopia correction, no significant differences were found in the MTF cutoff frequency, Strehl ratio and OSI, however, the lID analyzer accommodation range significantly differed postoperatively （P=0.004）. Postoperative CS at 12 and 18 cpd at near showed statistically significant improvement （P=0.020 and 0.008, respectively）. Visual performance by self-reported questionnaire revealed satisfactory results in terms of subjective visual quality improvement. CONCLUSION： Objective optical quality parameters show good visual outcomes. Subjective visual quality assessed by self-reported questionnaire in the presbyopia correction group show satisfactory results.

关键词： presbyopia correction laser blended vision visual quality LASIK

Transparent neural implantable devices:a comprehensive review of challenges and progress

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npj Flexible Electronics 2022年第1期6卷 439-456页

作者： young Uk Cho Se Lin lim Jung-Hoon Hong Ki Jun Yu Department of Electrical and Electronic Engineering Yonsei UniversitySeoulKorea Department of Electrical and Electronic Engineering YU-Korea Institute of Science and Technology InstituteYonsei UniversitySeoulKorea

The key to designing an implantable device lies in condensing the synergistic effects of diagnostic and therapeutic methods in a single *** conjunction with the integration of electrophysiology and optical modalities,a transparent neural interface alleviates challenges of conventional metal-based *** this review,the multimodal sensing and stimulation functionalities of recent research are ***,issues that arise when combining functionalities of conventional metal-based,opaque electrode arrays together with optical modalities—(1)photoelectric artifacts,(2)optical image blocking,and(3)light transmission efficiency—are ***,an introduction of advancing material candidates for transparent neural interfaces follows with the latest research.

关键词： neural transparent modal

Tai Chi for Management of Type 2 Diabetes Mellitus:A Systematic Review

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Chinese Journal of Integrative Medicine 2011年第10期17卷 789-793页

作者： Myeong Soo Lee Tae-young Choi Hyun-Ja lim Edzard Ernst Division of Standard Research Korea Institute of Oriental MedicineDaeieonSouth Korea Complementary Medicine Peninsula Medical SchoolUniversity of ExeterExeterUK Division of Standard Research Korea Institute of Oriental MedicineDaejeonSouth Korea Department of Nursing Chodang UniversityMuanSouth Korea

Objective： Tai chi has been recommended for treating type 2 diabetes mellitus. The purpose of this systematic review was to evaluate evidence from controlled clinical trials testing the effectiveness of tai chi in treating type 2 diabetes mellitus. Methods： Systematic searches were conducted on 14 electronic databases without restrictions on either population characteristics or language of publication. The outcome measures considered for inclusion were changes in fasting blood glucose （FBG）, glycosylated haemoglobin A1c （HbA1c） and quality of life （QOL）. Results： Eight randomised clinical trials （RCTs） and two controlled clinical trials （CCTs） met all inclusion criteria. Three RCTs from 1 trial compared the effects of tai chi with sham exercise and failed to show effectiveness of tai chi on FBG, HbA1c, or QOL. The other 3 RCTs tested the effects of tai chi compared with other types of exercise on FBG. The meta-analysis failed to show an FBG-lowering effect of tai chi [n=118, weighted mean difference （WMD）： -0.14 mmol/L, 95% CI：-0.86 to 0.58,P=0.70]. Four studies （2 RCTs and 2 CCT） compared tai chi with no treatment or self-management programme and failed to report significant differences between the experimental and control groups except for QOL from 1 RCT and 1 CCT. Conclusion： The existing evidence does not suggest that tai chi is an effective therapy for type 2 diabetes. Currently, there are few high-quality trials on which to make definitive judgements.

关键词： type 2 diabetes mellitus tai chi fast blood glucose complementary medicine