检索结果-南通市图书馆

数字化趋势下物流企业资源整合能力对服务效率的影响

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

商业经济 2024年第2期 81-83,139页

作者：孙晓维 young seok ock 釜庆大学技术经营专门大学院韩国釜山48547

随着数字化趋势的兴起,物流企业面临着资源整合的挑战,数字化趋势下物流企业资源整合能力对服务效率存在重要影响。数字化趋势下,物流企业的资源整合能力对服务效率的影响路径主要包括技术平台整合、数据整合与分析、人力资源整合以及... 详细信息

随着数字化趋势的兴起,物流企业面临着资源整合的挑战,数字化趋势下物流企业资源整合能力对服务效率存在重要影响。数字化趋势下,物流企业的资源整合能力对服务效率的影响路径主要包括技术平台整合、数据整合与分析、人力资源整合以及流程优化与创新,这些路径的有效整合和应用将有助于提升物流企业的服务效率,满足客户的需求并保持竞争优势,因此物流企业可以通过强化内部技术平台整合、优化数据整合与分析、做好人力资源整合、推进流程优化与创新来提升资源整合能力,以此促进服务效率提升。

关键词：数字化趋势资源整合能力服务效率物流企业

维普期刊数据库博看期刊

国际直接投资与高新技术企业自主创新关系的实证分析

在线全文

学校读者我要写书评

暂无评论

工业技术经济 2024年第7期43卷 131-138页

作者：丛识吴灏文玉英硕釜庆大学技术经营专门大学院韩国釜山48547 大连理工大学经济管理学院大连116086

为充分发挥国际直接投资对高新技术企业自主创新的促进作用,本文以2010~2022年的电子及通信设备制造业面板数据为基础,就国际直接投资与高新技术企业自主创新的关系进行实证研究。通过选取自变量、因变量、控制变量、门限变量,进行描述... 详细信息

为充分发挥国际直接投资对高新技术企业自主创新的促进作用,本文以2010~2022年的电子及通信设备制造业面板数据为基础,就国际直接投资与高新技术企业自主创新的关系进行实证研究。通过选取自变量、因变量、控制变量、门限变量,进行描述性统计、回归分析、稳健性检验和内生性检验,分析因变量和自变量之间的关系。结果表明:电子及通信设备制造业自主创新存在明显差异,其中,技术投入资金反向抑制其自主创新,而国际直接投资、研发人力资本、研发人员报酬、企业规模、国家研发补贴、市场经营状况、对外开放水平正向促进其自主创新;电子及通信设备制造业与技术投入资金之间存在一对协整关系,与国际直接投资、研发人力资本、企业规模、研发人员报酬、国家研发补贴、市场经营状况、对外开放水平均存在两对协整关系,且均在1%显著性水平下显著相关;国际直接投资可正向促进电子及通信设备制造业自主创新,并随着研发人力资本门限值的增大,促进作用表现为先下降后上升的特点;将研发人力资本的门限值设定为小于11.364,可更好发挥国际直接投资对电子及通信设备制造业的自主创新促进作用。基于实证结果得出,要进一步发挥国际直接投资对高新技术企业自主创新的促进作用,需要从改善投资环境、引进研发人员、加大投入资金、营造自主创新氛围、加强行业对外开放、开展良性行业竞争等对策入手。

关键词：国际直接投资高新技术企业电子及通信设备制造业自主创新协整关系门限效应研发人力资本企业规模

Korean Morphological Analysis for Korean-Vietnamese Statistical Machine Translation

在线全文

学校读者我要写书评

暂无评论

Journal of Electronic Science and Technology 2017年第4期15卷 413-419页

作者： Quang-Phuoc Nguyen Joon-Choul Shin Cheol-young ock Department of IT Convergence University of Ulsan Ulsan 44610 Republic of Korea

This paper describes the experiments with Korean-to-Vietnamese statistical machine translation(SMT). The fact that Korean is a morphologically complex language that does not have clear optimal word boundaries causes a major problem of translating into or from Korean. To solve this problem, we present a method to conduct a Korean morphological analysis by using a pre-analyzed partial word-phrase dictionary(PWD).Besides, we build a Korean-Vietnamese parallel corpus for training SMT models by collecting text from multilingual magazines. Then, we apply such a morphology analysis to Korean sentences that are included in the collected parallel corpus as a preprocessing step. The experiment results demonstrate a remarkable improvement of Korean-to-Vietnamese translation quality in term of bi-lingual evaluation understudy(BLEU).

关键词： Factored translation models Korean-Vietnamese parallel corpus morphological analysis statistical machine translation(SMT)

8-Hydroxydeoxyguanosine:Not mere biomarker for oxidative stress,but remedy for oxidative stress-implicated gastrointestinal diseases

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2012年第4期18卷 302-308页

作者： Chan-young ock Eun-Hee Kim Duck Joo Choi Ho Jae Lee Ki-Baik Hahm Myung Hee Chung Lab of Translational Medicine Gachon University of Medicine and ScienceLee Gil Ya Cancer and Diabetes Institute Department of Gastroenterology Gachon Graduate School of MedicineGil Hospital Sungkyunkwan University Samsung Advanced Institute for Biomedical Research

Reactive oxygen species (ROS) attack guanine bases in DNA easily and form 8-hydroxydeoxyguanosine (8-OHdG),which can bind to thymidine rather than cytosine,based on which,the level of 8-OHdG is gen-erally regarded as a biomarker of mutagenesis conse-quent to oxidative *** example,higher levels of 8-OHdG are noted in Helicobacter pylori-associated chronic atrophic gastritis as well as gastric ***,we have found that exogenous 8-OHdG can paradoxically reduce ROS production,attenuate thenuclear factor-κB signaling pathway,and ameliorate the expression of proinflammatory mediators such as interleukin (IL)-1,IL-6,cyclo-oxygenase-2,and induc-ible nitric oxide synthase in addition to expression of nicotinamide adenine dinucleotide phosphate oxidase (NOX)-1,NOX organizer-1 and NOX activator-1 in vari-ous conditions of inflammation-based gastrointestinal (GI) diseases including gastritis,inflammatory bowel disease,pancreatitis,and even colitis-associated *** recent finding that exogenous 8-OHdG was very effective in either inflammation-based or oxidative-stress-associated diseases of stress-related mucosal damage has inspired the hope that synthetic 8-OHdG can be a potential candidate for the treatment of inflammation-based GI diseases,as well as the pre-vention of inflammation-associated GI *** this editorial review,the novel fact that exogenous 8-OHdG can be a functional molecule regulating oxidative-stress-induced gastritis through either antagonizing Rac-guanosine triphosphate binding or blocking the signals responsible for gastric inflammatory cascade is introduced.

关键词：胃肠道疾病氧化应激生物标志物补救办法羟基烟酰胺腺嘌呤二核苷酸信号转导通路炎症介质

Splenic infarction associated with sorafenib use in a hepatocellular carcinoma patient

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2011年第2期17卷 267-270页

作者： Sang ock Kim Sang young Han Yang Hyun Baek Sung Wook Lee Ji Sun Han Byung Geun Kim Jin Han Cho Kyung Jin Nam Department of Gastroenterology and Hepatology Dong-A University HospitalDongdaesin-dong Seo-gu Busan 602-103 South Korea Dong-A University Collegeof Medicine 3-ga Dongdaesing-dong Seo-gu Busan 602-103South Korea Department of Radiology Dong-AUniversity Hospital Dongdaesin-dong Seo-gu Busan 602-103South Korea

Sorafenib,a multitargeted tyrosine kinase inhibitor,has been shown to improve survival in patients with advanced hepatocellular carcinoma(HCC).As the clinical use of sorafenib increases,many adverse effects have been reported,such as hand-foot skin reaction,diarrhea,anorexia,asthenia,alopecia,weight loss,hypertension and arterial ***,there are no prior reports of splenic infarction as an adverse effect of ***,a case of splenic infarction in a patient with HCC who was treated with sorafenib is reported. The patient had no other predisposing factors to explain the splenic infarction except for the administration of *** splenic infarction improved after sorafenib was discontinued;however,the HCC progressed.

关键词：肝癌酪氨酸激酶抑制剂脾癌病临床使用诱发因素存活率 HCC

Stevens-Johnson Syndrome and Hypothermia Associated with Anti-tuberculosis Medication in a Patient with Heart Failure

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Medical Journal 2015年第20期128卷 2837-2838页

作者： Sang-Ok Jung Min-Ji Cho Dong-II Park Sun-young Kim Ju-ock Kim Sung-Soo Jung Hee-Sun Park Jeong-Eun Lee Jae-young Moon Chae-Uk Chung Department of Internal Medicine Division of Pulmonology and Critical Care Medicine College of Medicine Chungnam National University Hospital Jung-gu Daejeon 301-721 Korea

To the Editor： Although rare, multiple adverse events associated with anti-tuberculosis （TB） medication can occur simultaneously in patients with underlying diseases. Here, we describe a 76-year-old man with several preexisting disorders in whom anti-TB medication caused multiple, simultaneous adverse events, including Stevens-Johnson syndrome （SJS）, hypothermia, and lactic acidosis.

关键词： tuberculosis patient diseases

Clinical significance of loss of heterozygosity for M6P/IGF2R in patients with primary hepatocellular carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2008年第9期14卷 1394-1398页

作者： Hong seok Jang Ki Mun Kang Byung ock Choi Gyu young Chai Soon Chan Hong Woo Song Ha Randy L Jirtle Department of Radiation Oncology The Catholic University of Korea School of Medicine SeoulKorea Department of Radiation Oncology Gyeongsang National University Postgraduate School of MedicineGyeongsang Institute of Health Sciences Jinju 660-702Korea Department of Radiation Oncology The Catholic University of Korea School of MedicineSeoulKorea Department of Radiation Oncology Gyeongsang National University Postgraduate School of MedicineGyeongsang Institute of Health SciencesJinju 660-702 Korea Department of Surgery Gyeongsang National UniversityPostgraduate School of MedicineJinju 660-702Korea Department of Surgery Gyeongsang National University Postgraduate School of MedicineJinju 660-702Korea Department of Radiation Oncology Duke University Medical CenterDurhamNCUnited States

AIM:To investigate the relationship between loss of heterozygosity (LOH) for mannose 6-phosphate/insulin- like growth factor 2 receptor (M6P/IGF2R) and the outcomes for primary HCC patients treated with partial hepatectomy. METHODS: The LOH for M6P/IGF2R in primary HCC patients was assessed using six different gene-specific nucleotide polymorphisms. The patients studied were enrolled to undergo partial hepatectomy. RESULTS: M6P/IGF2R was found to be polymorphic in 73.3% (22/30) of the patients, and of these patients, 50.0% (11/22) had tumors showing LOH in M6P/IGF2R. Loss of heterozygosity in M6P/IGF2R was associated with significant reductions in the two year overall survival rate (24.9% vs 65.5%; P = 0.04) and the disease-free survival rate (17.8% vs 59.3%; P = 0.03). CONCLUSION: These results show M6P/IGF2R LOH predicts poor clinical outcomes in surgically resected primary HCC patients.

关键词：原发性肝细胞癌异型结合性甘露糖6-磷酸盐胰岛素样生长因子肝切除术

Therapeutic potential of Gastrodia elata Blume for the treatment of Alzheimer's disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2013年第12期8卷 1061-1070页

作者： Guang-Biao Huang Tong Zhao Sushma Shrestha Muna Hong-Mei Jin Jong-Il Park Kyu-Sik Jo Bo-Hee Lee Soo-Wan Chae Sun-young Kim Soo-Hyun Park Eun-ock Park Eun-Kyung Choi young-Chul Chung Department of Psychiatry Chonbuk National University Medical SchoolJeonju 561-756 Republic of Korea Muju Chunma Native Local Industrial Center Muju 568-844 Republic of Korea Clinical Trial Center for Functional Foods Chonbuk National University HospitalJeonju 561-756 Republic of Korea Department of Pharmacology Chonbuk National University Medical SchoolJeonju 561-756 Republic of Korea

Several studies have demonstrated that the Chinese herb Gastrodia elata Blume can protect against amyloid beta-peptide （Ap）-induced cell death. To investigate the possible therapeutic effects of Gastrodia elata Blume on Alzheimer＇s disease, we established a rat model of AIzheimer＇s disease by injecting A325-35 into bilateral hippocampi. These rats were intragastrically administered 500 or 1 000 mg/kg Gastrodia elata Blume per day for 52 consecutive days. Morris water maze tests showed that Gastrodia elata Blume treatment significantly improved the spatial memory of Alzheimer＇s disease rats. Congo red staining revealed that Gastrodia elata Blume significantly reduced the number of amyloid deposits in the hippocampus of these rats. Western blot analysis showed that choline acetyltransferase expression in the medial septum and hippocampus was significantly increased by the treatment of Gastrodia elata Blume, while EIIman method showed significant decrease in the activity of acetylcholinesterase in all three regions （prefrontal cortex, medial septum and hippocampus）. These findings suggest that long-term administration of Gastrodia elata Blume has therapeutic potential for Alzheimer＇s disease.

关键词： neural regeneration neuroprotective effect Traditional Chinese medicine Gastrodia elata Blume Alzheimer's disease Morris water maze test choline acetyltransferase acetylcholinesterase grants-supported paper neuroregeneration

Programmed death ligand-1 expression and its prognostic role in esophageal squamous cell carcinoma

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2016年第37期22卷 8389-8397页

作者： Ryul Kim Bhumsuk Keam Dohee Kwon Chan-young ock Miso Kim Tae Min Kim Hak Jae Kim Yoon Kyung Jeon In Kyu Park Chang Hyun Kang Dong-Wan Kim young Tae Kim Dae Seog Heo Department of Internal Medicine Seoul National University HospitalSeoul 03080South Korea Cancer Research Institute Seoul National University College of MedicineSeoul 03080South Korea Department of Pathology Seoul National University HospitalSeoul 03080South Korea Department of Radiation Oncology Seoul National University HospitalSeoul 03080South Korea Department of Thoracic and Cardiovascular Surgery Seoul National University HospitalSeoul 03080South Korea

AIM To investigate the expression and prognostic role of programmed death ligand-1(PD-L1) in locally advanced esophageal squamous cell carcinoma(ESCC).METHODS A total of 200 patients with ESCC who underwent radical esophagectomy with standard lymphadenectomy as the initial definitive treatment in Seoul National University Hospital from December 2000 to April 2013 were eligible for this analysis. Tissue microarrays were constructed by collecting tissue cores from surgical specimens, and immunostained with antibodies directed against PD-L1, p16, and c-Met. Medical records were reviewed retrospectively to assess clinical outcomes. Patients were divided into two groups by PD-L1 status, and significant differences in clinicopathologic characteristics between the two groups were assessed. RESULTS Tumor tissues from 67 ESCC patients(33.5%) were PDL1-positive. Positive p16 expression was observed in 21 specimens(10.5%). The H-score for c-Met expression was ≥ 50 in 42 specimens(21.0%). Although PDL1-positivity was not significantly correlated with any clinical characteristics including age, sex, smoking/alcoholic history, stage, or differentiation, H-scores for c-Met expression were significantly associated with PDL1-positivity(OR = 2.34, 95%CI: 1.16-4.72, P = 0.017). PD-L1 expression was not significantly associated with a change in overall survival(P = 0.656). In contrast, the locoregional relapse rate tended to increase(P = 0.134), and the distant metastasis rate was significantly increased(HR = 1.72, 95%CI: 1.01-2.79, P = 0.028) in patients with PD-L1-positive ESCC compared to those with PD-L1-negative *** PD-L1 expression is positively correlated with c-Met expression in ESCC. PD-L1 may play a critical role in distant failure and progression of ESCC.

关键词： Esophageal neoplasm Programmed death ligand-1 protein c-Met protein Prognosis p16INK4A protein