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Clinical characteristics of sibling patients with comitant strabismus

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International Journal of Ophthalmology(English edition) 2017年第5期10卷 772-775页

作者： Haeng Jin Lee Seong-joon Kim young Suk Yu Department of Ophthalmology Seoul National University College of Medicine Seoul 110-744 Korea Seoul Artificial Eye Center Seoul National University Hospital Clinical Research Institute Seoul 110-744 Korea

AIM：To investigate the clinical characteristics of sibling patients with comitant strabismus. METHODS：Sibling patients who were diagnosed with comitant strabismus from January 2005 to December 2014 were retrospectively reviewed. Factors including age, sex, types of strabismus, refractive errors, angle of deviation, and coexistence of other strabismus were analyzed. RESULTS：A total of 62 patients（31 pairs of siblings） were included. Of these, 26 pairs had intermittent exotropia, 3 had accommodative esotropia, and 2 had infantile esotropia. There were no pairs with different subtypes of strabismus. The age at first visit was 3.7±2.6y and the mean follow-up period was 30.5±24.1mo. In siblings with intermittent exotropia, there was no difference in age of onset, age at operation, or refractive errors between the first and second-born children. The 20（77%） pairs of siblings with exotropia showed more than 80% concordance of maximum angle of deviation during follow-up. In the 9 pairs in which both siblings had an operation, the final angle of deviation after the operation was 8.2±8.1 prism diopters（PD） in first-born children and 8.6±6.5 PD in second-born children. CONCLUSION：The subtypes of strabismus are the same in all pairs of siblings and clinical characteristics of strabismus are similar between the first and secondborn children. This similarity could be an indicator for the diagnosis of second-born children. Further prospective study including a larger number of sibling patients is needed.

关键词： siblings clinical characteristics strabismus

Self-Assembled Wire Arrays and ITO Contacts for Silicon Nanowire Solar Cell Applications

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Chinese Physics Letters 2011年第3期28卷 132-135页

作者： YANG Cheng ZHANG Gang LEE Dae-young LI Hua-Min LIM young-Dae yoo Won Jong PARK young-Jun KIM Jong-Min Sungkyunkwan University SKKU Advanced Institute of Nano Technology300 Cheoncheon-dongJangan-guSuwon 440-746Korea Samsung Electronics Co.Ltd. San 14-1 Nongseo-dongGiheung-guYongin 446-712Korea

Self-assembly of silicon nanowire(SiNW)arrays is studied using SF_(6)/0_(2)plasma *** self-assembly method can be applied to single-and poly-crystalline Si *** conditions can control the length and diameter of the SiNW *** reflectance of the wire arrays over the wavelength range 200-1100nm is *** conducting transparent indium-tin-oxide(ITO)electrode can be fully coated on the self-assembled SiNW arrays by *** ITO-coated SiNW solar cells show the same low surface light reflectance and a higher carrier collection efficiency than SiNW solar cells without ITO *** efficiency enhancement of around 3 times for ITO coated SiNW solar cells is demonstrated via experiments.

关键词： reflectance Solar transparent

GIGANTEA Shapes the Photoperiodic Rhythms of Thermomorphogenic Growth in Arabidopsis

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Molecular Plant 2020年第3期13卷 459-470页

作者： young-joon Park Jae young Kim June-Hee Lee Byoung-Doo Lee Nam-Chon Paek Chung-Mo Park Department of Chemistry Seoul National UniversitySeoul 08826Korea Department of Plant Science Seoul National UniversitySeoul 08826Korea Plant Genomics and Breeding Institute Seoul National UniversitySeoul 08826Korea These authors contributed equally to this article

Plants maintain their internal temperature under environments with fluctuating temperatures by adjusting their morphology and architecture,an adaptive process termed ***,the rhythmic patterns of plant thermomorphogenesis are governed by day-length ***,it remains elusive how thermomorphogenic rhythms are regulated by ***,we show that warm temperatures enhance the accumulation of the chaperone GIGANTEA(Gl),which thermostabilizes the DELLA protein,REPRESSOR OF ga1-3(RGA),under long days,thereby attenuating PHYTOCHROME INTERACTING FACTOR 4(PIF4)-mediated *** contrast,under short days,when Gl accumulation is reduced,RGA is readily degraded through the gibberellic acid-mediated ubiquitination-proteasome pathway,promoting thermomorphogenic *** data indicate that the GI-RGA-PIF4 signaling module enables plant thermomorphogenic responses to occur in a day-length-dependent *** propose that the Gl-mediated integration of photoperiodic and temperature information shapes thermomorphogenic rhythms,which enable plants to adapt to diel fluctuations in day length and temperature during seasonal transitions.

关键词： thermomorphogenesis day length Gl RGA PIF4

pH-induced structural changes of surface immobilized poly (L-lysine) by two-dimensional (2D) infrared correlation study

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Chinese Chemical Letters 2015年第2期26卷 173-176页

作者： Eun Joo yoo Boknam Chae young Mee Jung Seung Woo Lee School of Chemical Engineering Yeungnam University Pohang Accelerator Laboratory Department of Chemistry Kangwon National University

This paper reports the pH-induced structural changes in the surface immobilized poly（L-lysine）（PLL）***-dimensional（2D） correlation analysis was applied to the Fourier transform infrared（FTIR）spectra of the surface-immobilized PLL film to examine the spectral changes induced by the alternations of the protonation state of the amino group in the side *** spectral changes in the FTIR spectra of the PLL film were observed between pH 7 and *** decrease in the protonation state of the amino group in the side chain induced spectral changes in the amino group as well as conformational changes in the alky]group in the side *** pH 1-8,the spectral changes in the amino and alkyl groups in the side chain occurred before those of the amide group in the main chain of the surface immobilized PLL film.

关键词： Poly(L-lysine)(PLL) Surface-immobilized polypeptide FT-IR spectroscopy 2D correlation spectroscopy

The efficacy of *** adjuvant chemotherapy on biliary tract cancer after R0 resection

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Chinese Journal of Cancer 2017年第5期36卷 222-230页

作者： young Saing Kim Chi-young Jeong Haa-Na Song Tae Hyo Kim Hong Jun Kim young-joon Lee Soon Chan Hong Division of Hematology and Oncology Department of Internal MedicineGachon University Gil Medical Center Incheon 405.706 South Korea Department of Surgery Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine 79 Gangnam-roJinju 660.702 South Korea Department of Internal Medicine Institute of Health Sciences Gyeongsang National University Hospital Gyeongsang National University School of Medicine Jinju 660.702 South Korea.

Background: The optimal treatment strategy for biliary tract cancer(BTC) after curative?intent resection remains con?troversial. The purpose of this study was to evaluate the efficacy of fluoropyrimidine?based adjuvant chemotherapy for BTC patients undergoing microscopically margin?negative(R0) ***: We retrospectively analyzed the clinical data of BTC patients who underwent curative?intent R0 resection. Patients were eligible if they received either fluoropyrimidine?based adjuvant chemotherapy or observation after R0 ***: A total of 153 patients were included. In the entire patient cohort, no significant differences were observed in 5?year overall survival(OS) rates(48.4% vs. 39.6%, P = 0.439) or 3?year recurrence?free survival(RFS) rates(49.1% vs. 39.5%, P = 0.299) between patients who received fluoropyrimidine?based adjuvant chemotherapy or observation. However, for patients with stages Ⅱ and Ⅲ BTC, chemotherapy significantly improved 5?year OS rate(52.4% vs. 35.6%, P = 0.002) and 3?year RFS rate(55.5% vs. 39.1%, P = 0.021) compared with ***: Fluoropyrimidine?based adjuvant chemotherapy may prolong the survival of patients with stages Ⅱ and Ⅲ BTC after R0 resection.

关键词： Biliary tract cancer Adjuvant chemotherapy Fluoropyrimidine R0 resection Prognosis

Structural Analysis of FRIGIDA Flowering-Time Regulator

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Molecular Plant 2016年第4期9卷 618-620页

作者： Kyung-gi Hyun JeeEun Oh Jihye Park yoo-Sun Noh Ji-joon Song School of Biological Sciences Seoul National University Seoul 151-747 Korea

Dear Editor,Flowering is a major developmental switch in the life cycle of flowering plants. FRIGIDA （FRI） activates FLOWERING LOCUS C （FLC） transcription, a major repressor of this switch regulating flow- ering time （Johanson et al., 2000）. FRI is highly conserved and many natural variations in FRI are found to affect flowering time. However, little is known about the molecular characteristics of FRI.

关键词： LOCUS in plant genetics FLOWERING time MOLECULAR structure

Improvement in Sensitivity and Recovery of Single-Walled Carbon Nanotube-Based Gas Sensors

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稀有金属材料与工程 2006年第A03期35卷 188-189页

作者： Hong-Quang Nguyen Geon-young Cha joon-Boo Yu Jeung-Soo Huh Department of Materials Science and Metallurgy Kyungpook National UniversitySangyuk-DongBukgu 1370Daegu 702-701Korea

In this paper,an improvement in sensitivity and recovery of the single-walled carbon nanotube (SWNT)-based gas sensors was *** sensors were fabricated from SWNT powder by a screen-printing method,followed by annealing for 2 h in open-air at various *** Raman spectra of the SWNT bundles and the response to ammonia (NH_3) exposure of the sensors indicated that the annealing at a relevant temperature improved the sensor *** sensor annealed at 200℃exhibited a high sensitivity in NH_3 *** 20 min of exposure to NH_3 at room temperature,the resistance of the sensor increased up to 12% in comparison with its initial *** evacuating combined with maintaining the flux of carrier gas at 300 sccm,the sensor recovery was significantly *** sensor resistance retrieved to its initial value after only 25 min degassing. These results would be considered in the development of the SWNT-based gas sensors.

关键词： carbon nanotubes gas adsorption recovery sensitivity sensor

Parallel Iterative FEM Solver with Initial Guess for Frequency Domain Electromagnetic Analysis

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Intelligent Automation & Soft Computing 2023年第5期36卷 1585-1602页

作者： Woochan Lee Woobin Park Jaeyoung Park young-joon Kim Moonseong Kim Department of Electrical Engineering Incheon National UniversityIncheon22012Korea Department of Computer Engineering Hongik UniversitySeoul04066Korea Department of Electronic Engineering Gachon UniversitySeongnam13120Korea Department of IT Convergence Software Seoul Theological UniversityBucheon14754Korea

The finite element method is a key player in computational electromag-netics for designing RF(Radio Frequency)components such as *** frequency-domain analysis is fundamental to identify the characteristics of the *** the conventional frequency-domain electromagnetic analysis using FEM(Finite Element Method),the system matrix is complex-numbered as well as indeﬁ*** iterative solvers can be faster than the direct solver when the solver convergence is guaranteed and done in a few ***,such complex-numbered and indeﬁnite systems are hard to exploit the merit of the iterative *** is also hard to beneﬁt from matrix factorization techniques due to varying system matrix parts according to ***,it is hard to adopt conventional iterative solvers even though the system matrix is sparse.A new parallel iterative FEM solver for frequency domain analysis is implemented for inhomogeneous waveguide structures in this *** this implementation,the previous solution of the iterative solver of Matlab(Matrix Laboratory)employ-ing the preconditioner is used for the initial guess for the next step’s solution *** overlapped parallel stage using Matlab’s Parallel Computing Toolbox is also proposed to alleviate the cold starting,which ruins the convergence of early steps in each parallel *** experiments based on waveguide structures have demonstrated the accuracy and efﬁciency of the proposed scheme.

关键词： Computational electromagnetics numerical simulation ﬁnite element method parallel processing iterative solvers

Disharmonious Ventricular Relationship and Topology for the Given Atrioventricular *** Diagnostic Approach Using 3D Modeling and Printing

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Congenital Heart Disease 2022年第5期17卷 495-504页

作者： Shi-joon yoo Ankavipar Saprungruang Christopher Z.Lam Robert H.Anderson Department of Diagnostic Imaging Hospital for Sick ChildrenUniversity of TorontoTorontoCanada Division of Cardiology Department of PediatricsLabatt Family Heart CentreHospital for Sick ChildrenUniversity of TorontoTorontoCanada Biosciences Division Newcastle UniversityNewcastle-upon-TyneUK

In the last issue,two case reports separately present examples of the extremely rare and complex congenital heart diseases that show concordant atrioventricular connections to the L-looped ventricles in the presence of situs *** cases highlight that the relationship between the two ventricles within the ventricular mass is not always harmonious with the given atrioventricular *** disharmony between the connections and relationships requires careful assessment of the three basic facets of cardiac building blocks,namely their morphology,the relationship of their component parts,and their connections with the adjacent segments.3D imaging and printing can now facilitate an otherwise difficult diagnosis in such complex *** of either the 3D images or the models permit accurate assessment of the ventricular topologic pattern by creating the right ventricular en-face septal view,thus facilitating placement of the observer’s *** we now emphasize,an alternative approach,which might prove more attractive to imagers,is to rotate the ventricular mass to provide the ventricular apical view,thus permitting determination of the ventricular relationship without using the hands.

关键词： Segmental approach disharmony between connection and relationship ventricular loop pattern ventricular topology juxtaposition of atrial appendages 3D modeling 3D printing