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World Journal of Gastroenterology 2014年第35期20卷 12687-12690页

作者： Ji Eun kim Tae-Geun Gweon Chang Dong Yeo young-Seok Cho Gi Jun kim jae young kim Jong Wook kim Hyunho kim Hye Won Lee Taeseok Lim Hyoju Ham Hyun Jin Oh Yeongbok Lee jaeho Byeon Sung Soo Park Department of Internal Medicine Seoul St Mary’s hospitalThe Catholic University of KoreaCollege of Medicine Division of Gastroenterology Department of Internal MedicineSeoul St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine Division of Pulmonology Department of Internal MedicineUijeongbu St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine Division of Gastroenterology Department of Internal MedicineUijeongbu St.Mary’s HospitalThe Catholic University of KoreaCollege of Medicine

Acute respiratory distress syndrome is a life-threatening disorder caused mainly by *** difficile infection(CDI)is a common nosocomial diarrheal *** of normal intestinal flora by antibiotics is the main risk factor for *** use of broadspectrum antibiotics for serious medical conditions can make it difficult to treat CDI complicated by acute respiratory distress *** microbiota transplantation is a highly effective treatment in patients with refractory *** we report on a patient with refractory CDI and acute respiratory distress syndrome caused by pneumonia who was treated with fecal microbiota transplantation.

关键词： Clostridium difficile infection Acute respiratory distress syndrome Fecal microbiota transplantation

Stable immobilization of lithium polysulfides using three-dimensional ordered mesoporous Mn_(2)O_(3) as the host material in lithium-sulfur batteries

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Carbon Energy 2024年第6期6卷 99-112页

作者： Sung Joon Park Yun Jeong Choi Hyun-seung kim Min Joo Hong Hongjun Chang Janghyuk Moon young-Jun kim Junyoung Mun Ki jae kim Department of Energy Science Sungkyunkwan UniversitySuwonGyeonggi-doRepublic of Korea Department of Energy Engineering Konkuk UniversitySeoulRepublic of Korea Advanced Batteries Research Center Korea Electronic Technology InstituteSeongnamRepublic of Korea Department of Future Energy Engineering Sungkyunkwan UniversitySuwonRepublic of Korea Department of Energy Systems Engineering Chung-Ang UniversitySeoulRepublic of Korea SKKU Advanced Institute of Nanotechnology Sungkyunkwan UniversitySuwonGyeonggi-doRepublic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwonRepublic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwonRepublic of Korea

Lithium-sulfur batteries(LSBs)have drawn significant attention owing to their high theoretical discharge capacity and energy ***,the dissolution of long-chain polysulfides into the electrolyte during the charge and discharge process(“shuttle effect”)results in fast capacity fading and inferior electrochemical *** this study,Mn_(2)O_(3)with an ordered mesoporous structure(OM-Mn_(2)O_(3))was designed as a cathode host for LSBs via KIT-6 hard templating,to effectively inhibit the polysulfide shuttle ***-Mn_(2)O_(3)offers numerous pores to confine sulfur and tightly anchor the dissolved polysulfides through the combined effects of strong polar-polar interactions,polysulfides,and sulfur chain *** OM-Mn_(2)O_(3)/S composite electrode delivered a discharge capacity of 561 mAh g^(-1) after 250 cycles at 0.5 C owing to the excellent performance of OM-Mn_(2)O_(3).Furthermore,it retained a discharge capacity of 628mA h g^(-1) even at a rate of 2 C,which was significantly higher than that of a pristine sulfur electrode(206mA h g^(-1)).These findings provide a prospective strategy for designing cathode materials for high-performance LSBs.

关键词： host material lithium-sulfur battery ordered mesoporous structure shuttle effect transition-metal oxides

Improvement of Cu-Pillar Structure Using Advanced Plating Method

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材料科学与工程（中英文B版） 2017年第6期7卷 247-251页

作者： Jong-young PARK young-jae kim Joo-Hyong NOH Hideo Honma Department of Materials and Surface Engineering Graduate School of Engineering Kanto Gakuin University Ogikubo 1162-2Odawara 250-0042 Japan Materials and Surface Engineering Research Institute Kanto Gakuin University 1162-20gikubo Odawara 250-0042 Japan Daeduck Electronics Co. Ltd. 335 Somanggongwon-ro Siheung-si Gyeonggi-do 15106 Korea

The recent appearance of mobile application processor now plays an important role in the semiconductor industry. Additionally, there have been endless demands for small form factor, thin profile, outstanding thermal, mechanical properties and electrical performances in the field of IC packages for mobile application processors. MIS (Molded Interconnect Substrate) can provide ideal and this solution in the mobile industry as it contains multiple solutions for the complicated requirement of the IC packages for application processors. Based on the embedded pattern technology, this solution can provide high I/O count, fine pattern for small form factor, and stable flip chip mounting methods. Other advantages of this solution include stable properties required for high-frequency transmission and high thermal dissipation rate as it is only composed of copper and epoxy mold compound materials. These core techniques for MIS technology can be divided into below major concepts. First, Cu pillar electrolytic plating technology electrically connects the inner and the outer layers using photo-lithography method, instead of laser method. The shape of Cu pillar and the plating thickness tolerance control are the key parameters. Second, grinding technology is to precisely grind the plated Cu pillars and applied mold epoxy. And deposition of Cu layer on top of grinded mold surface can construct fine pattern traces.

关键词：支柱结构 Cu 半导体工业机械性质处理器应用程序波的传播激光方法

Integration of earth-abundant cocatalysts for high-performance photoelectrochemical energy conversion

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Journal of Energy Chemistry 2024年第1期88卷 336-355,I0008页

作者： Joonhee Ma Sang Hyun Ahn Soo young kim Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea School of Chemical Engineering and Materials Science Chung-Ang University84 Heukseok-roDongjak-guSeoul 06974Republic of Korea

Photoelectrochemical(PEC)energy conversion has emerged as a promising and efficient approach to sustainable energy harvesting and *** utilizing semiconductor photoelectrodes,PEC devices can harness solar energy and drive electrochemical reactions such as water splitting or carbon dioxide(CO_(2))reduction to generate clean fuels and value-added ***,PEC energy conversion faces several challenges such as high overpotential,sluggish reaction kinetics,charge carrier recombination,and stability issues,which limit its practical ***,significant research has been conducted to improve the overall conversion efficiency of PEC *** particularly promising approach is the use of cocatalysts,which involves introducing specific cocatalysts onto the photoelectrode surface to promote charge separation,improve reaction kinetics,and reduce the overpotential,thereby enhancing the overall performance of PEC energy *** review provides a comprehensive overview of the recent developments in the earth-abundant cocatalysts for PEC water splitting and CO_(2) *** main earth-abundant catalysts for the PEC water splitting include transition-metal dichalcogenide(TMD)-based materials,metal phosphides/carbides,and metal oxides/***,PEC-CO_(2)RR was divided into C_(1) and C_(2+)based on the final product since various products could be produced,focusing on diverse earth-abundant materials-based *** addition,we provide and highlight key advancements achieved in the very recent reports on novel PEC system design engineering with ***,the current problems associated with PEC systems are discussed along with a suggested direction to overcome these obstacles.

关键词： Solar energy Photo-electrochemical Water splitting CO_(2)reduction Cocatalysts

Tailoring Classical Conditioning Behavior in TiO_(2) Nanowires:ZnO QDs-Based Optoelectronic Memristors for Neuromorphic Hardware

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Nano-Micro Letters 2024年第7期16卷 265-280页

作者： Wenxiao Wang Yaqi Wang Feifei Yin Hongsen Niu young-Kee Shin Yang Li Eun-Seong kim Nam-young kim School of Information Science and Engineering University of JinanJinan 250022People’s Republic of China RFIC Centre NDAC CentreKwangwoon UniversityNowon-guSeoul 139-701South Korea Department of Electronics Engineering Kwangwoon UniversityNowon-GuSeoul 139-701South Korea School of Microelectronics Shandong UniversityJinan 250101People’s Republic of China Department of Molecular Medicine and Biopharmaceutical Sciences Seoul National UniversitySeoul 08826South Korea

Neuromorphic hardware equipped with associative learn-ing capabilities presents fascinating applications in the next generation of artificial ***,research into synaptic devices exhibiting complex associative learning behaviors is still ***,an optoelec-tronic memristor based on Ag/TiO_(2) Nanowires:ZnO Quantum dots/FTO was proposed and constructed to emulate the biological associative learning *** implementation of synaptic behaviors,including long and short-term plasticity,and learning-forgetting-relearning behaviors,were achieved in the device through the application of light and electrical *** the optoelectronic co-modulated characteristics,a simulation of neuromorphic computing was conducted,resulting in a handwriting digit recognition accuracy of 88.9%.Furthermore,a 3×7 memristor array was constructed,confirming its application in artificial visual *** importantly,complex biological associative learning behaviors were emulated by mapping the light and electrical stimuli into conditioned and unconditioned stimuli,*** training through associative pairs,reflexes could be triggered solely using light ***-sively,under specific optoelectronic signal applications,the four features of classical conditioning,namely acquisition,extinction,recovery,and generalization,were elegantly *** work provides an optoelectronic memristor with associative behavior capabilities,offering a pathway for advancing brain-machine interfaces,autonomous robots,and machine self-learning in the future.

关键词： Artificial intelligence Classical conditioning Neuromorphic computing Artificial visual memory Optoelectronic memristors ZnO Quantum dots

Development of Three Dimensional Automatic Body Fat Measurement Software from CT, and Its Validation and Evaluation

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Journal of Biomedical Science and Engineering 2015年第10期8卷 665-673页

作者： young jae kim Jun Yong Jeong Su Youn Nam Min Ju kim jae Hwan Oh Kwang Gi kim Dae Kyung Sohn Biomedical Engineering Branch Division of Convergence Technology Research Institute National Cancer Center Goyang Korea Department of Plasma Bio Display Kwangwoon University Seoul Korea Department of Radiology Hospital National Cancer Center Goyang Korea Center for Cancer Prevention and Detection Hospital National Cancer Center Goyang Korea Center for Colorectal Cancer Hospital National Cancer Center Goyang Korea

Abdominal obesity describes the accumulation of excessive fat in the abdomen. It is known that depending on its distribution, visceral obesity presents a greater danger to health than subcutaneous obesity. To properly prevent and treat visceral obesity, accurate evaluation methods are necessary, and hence quantitative VAT estimation is extremely important. CT scans are the most accurate method for estimating VAT, but it requires a great deal of time and effort, limiting its use in studying or evaluating obesity in patients. This paper proposed automatic measurement software that could quickly differentiate between and measure VAT and SAT. The method was verified using a total of 100 abdominal CT data values;this paper measured the SAT and VAT in the entire abdomen using the automatic measurement software. Additionally, through a comparative evaluation between the automated measurements and manual measurements such as BMI and waist circumference, clinical reliability and viability were validated and evaluated. Between automated measurements and manual measurements, the TAT (r = 0.995, p = 0.01), SAT (r = 0.987, p = 0.01) and VAT (r = 0.993, p = 0.01) showed high correlation. Using BMI as the main metric, the TAT for automated measurements (r = 0.674, p = 0.01) and the TAT for manual measurements (r = 0.703, p = 0.01) showed the strongest correlation. When using waist circumference, the VAT for automated measurements (r = 0.826, p = 0.01) and the VAT for manual measurements (r = 0.822, p = 0.01) showed the strongest correlation. With these results, the reliability and viability of the automatic measurement software were confirmed. The software is expected to help greatly in reducing the time and in providing objective data of VAT measurements from CT scans for clinical research.

关键词： Abdominal Obesity Visceral Adipose Tissue (VAT) Subcutaneous Adipose Tissue (SAT) Computer-Aided Diagnosis (CAD) Computed Tomography (CT)

Hydrangea serrata extract exerts tumor inhibitory activity against hepatocellular carcinoma HepG2 cells via inducing p27/CDK2-mediated cell cycle arrest and apoptosis

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Asian Pacific Journal of Tropical Biomedicine 2024年第2期14卷 65-72,I0002-I0005页

作者： Ye-eun kim Jeonghye Hwang Ki-young kim Graduate School of Biotechnology Kyung Hee UniversitySeocheonGiheungYonginGyeonggi-do 446-701Republic of Korea Department of Genetics and Biotechnology College of Life SciencesKyung Hee UniversitySeocheonGiheungYonginGyeonggi-do 446-701Republic of Korea

Objective:To examine the inhibitory effect of Hydrangea serrata extract against hepatocellular carcinoma HepG2 cells and its underlying ***:The effects of Hydrangea serrata extract on growth inhibition of tumor cells and spheroids were assessed using MTT and 3D culture *** real-time PCR and Western blot analyses were employed to investigate the changes in mRNA and protein expression levels of molecules related to cell cycle and ***:Hydrangea serrata extract effectively inhibited the growth of both tumor cells and *** extract also significantly upregulated p27 mRNA expression and downregulated CDK2 mRNA expression,leading to cell cycle ***,increased BAX/Bcl-2 ratio as well as caspase-9 and-3 were observed after treatment with Hydrangea serrata extract,indicating the induction of tumor cell ***:Hydrangea serrata extract has the potential to alleviate tumors by effectively modulating cell-cycle-related gene expressions and inducing apoptosis,thereby inhibiting tumor growth.

关键词： Hydrangea serrata Hepatocellular carcinoma Liver cancer Anticancer Cell cycle arrest Apoptosis

Driving inward growth of lithium metal in hollow microcapsule hosts by heteroatom‐controlled nucleation

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Carbon Energy 2024年第8期6卷 262-272页

作者： Siwon kim Hong Rim Shin Ki jae kim Min‐Sik Park Jong‐Won Lee Division of Materials Science and Engineering Hanyang UniversitySeoulRepublic of Korea Department of Energy Science and Engineering Daegu Gyeongbuk Institute of Science and Technology(DGIST)DaeguRepublic of Korea Department of Energy Science Sungkyunkwan UniversitySuwonRepublic of Korea Department of Advanced Materials Engineering for Information and Electronics Integrated Education for Frontier Science and Technology(BK21 Four)Kyung Hee UniversityYonginRepublic of Korea

The application of Li metal anodes in rechargeable batteries is impeded by safety issues arising from the severe volume changes and formation of dendritic Li ***‐dimensional hollow carbon is receiving increasing attention as a host material capable of accommodating Li metal inside its cavity;however,uncontrollable and nonuniform deposition of Li remains a *** this study,we synthesize metal–organic framework‐derived carbon microcapsules with heteroatom clusters(Zn and Ag)on the capsule walls and it is demonstrated that Ag‐assisted nucleation of Li metal alters the outward‐to‐inward growth in the microcapsule ***‐incorporated microcapsules are prepared via chemical etching of zeolitic imidazole framework‐8 polyhedra and are subsequently decorated with Ag by a galvanic displacement reaction between Ag^(+)and metallic *** introduced Ag significantly reduces the energy barrier and increases the reaction rate for Li nucleation in the microcapsule host upon Li *** combined electrochemical,microstructural,and computational studies,we verify the beneficial role of Ag‐assisted Li nucleation in facilitating inward growth inside the cavity of the microcapsule host and,in turn,enhancing electrochemical *** study provides new insights into the design of reversible host materials for practical Li metal batteries.

关键词： hollow carbon hosts lithium metal batteries lithium plating metal-organic frameworks nucleation

Modification strategies improving the electrochemical and structural stability of high-Ni cathode materials

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Journal of Energy Chemistry 2024年第9期96卷 185-205页

作者： Yoon Bo Sim Hami Lee Junyoung Mun Ki jae kim Department of Energy Science Sungkyunkwan UniversitySuwon 16419Republic of Korea School of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon 16419Republic of Korea SKKU Institute of Energy Science and Technology(SIEST) Sungkyunkwan UniversitySuwon 16419Republic of Korea

With the increasing spotlight in electric vehicles,there is a growing demand for high-energy-density batteries to enhance driving ***,several studies have been conducted on high-energy-density LiNi_(x)Co_(y)Mn_(z)O_(2)***,there is a limit to permanent performance deterioration because of side reactions caused by moisture in the atmosphere and continuous microcracks during cycling as the Ni content to express high energy increases and the content of Mn and Co that maintain structural and electrochemical stabilization *** direct modification of the surface and bulk regions aims to enhance the capacity and long-term performance of high-Ni cathode ***,an efficient modification requires a study based on a thorough understanding of the degradation mechanisms in the surface and bulk *** this review,a comprehensive analysis of various modifications,including doping,coating,concentration gradient,and single crystals,is conducted to solve degradation issues along with an analysis of the overall degradation mechanism occurring in high-Ni cathode *** also summarizes recent research developments related to the following modifications,aims to provide notable points and directions for post-studies,and provides valuable references for the commercialization of stable high-energy-density cathode materials.

关键词： High energy density High-Ni cathode materials Degradation Structural stability Lithium-ion battery

Oxygen functionalization-assisted anionic exchange toward unique construction of flower-like transition metal chalcogenide embedded carbon fabric for ultra-long life flexible energy storage and conversion

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Carbon Energy 2024年第1期6卷 72-93页

作者： Roshan M.Bhattarai Kisan Chhetri Nghia Le Debendra Acharya Shirjana Saud Mai Cao Hoang Phuong Lan Nguyen Sang jae kim young Sun Mok Department of Chemical Engineering Jeju National UniversityJejuRepublic of Korea Department of Nano Convergence Engineering Jeonbuk National UniversityJeonjuRepublic of Korea Regional Leading Research Center(RLRC)for Nanocarbon-based Energy Materials and Application Technology Jeonbuk National UniversityJeonjuRepublic of Korea Department of Chemistry Mississippi State UniversityStarkvilleMississippiUSA Nanomaterials and System Laboratory Department of Mechatronics EngineeringJeju National UniversityJejuRepublic of Korea

The metal-organic framework(MOF)derived Ni–Co–C–N composite alloys(NiCCZ)were“embedded”inside the carbon cloth(CC)strands as opposed to the popular idea of growing them upward to realize ultrastable energy storage and conversion *** NiCCZ was then oxygen functionalized,facilitating the next step of stoichiometric sulfur anion diffusion during hydrothermal sulfurization,generating a flower-like metal hydroxysulfide structure(NiCCZOS)with strong partial implantation inside *** obtained NiCCZOS shows an excellent capacity when tested as a supercapacitor electrode in a three-electrode ***,when paired with the biomass-derived nitrogen-rich activated carbon,the asymmetric supercapacitor device shows almost 100%capacity retention even after 45,000 charge–discharge cycles with remarkable energy density(59.4 Wh kg^(-1)/263.8μWh cm^(–2))owing to a uniquely designed ***,the same electrode performed as an excellent bifunctional water-splitting electrocatalyst with an overpotential of 271 mV for oxygen evolution reaction(OER)and 168.4 mV for hydrogen evolution reaction(HER)at 10 mA cm−2 current density along with 30 h of unhinged chronopotentiometric stability performance for both HER and ***,a unique metal chalcogenide composite electrode/substrate configuration has been proposed as a highly stable electrode material for flexible energy storage and conversion applications.

关键词： carbon cloth energy conversion energy storage flexible metal embedding ultra-stable