检索结果-南通市图书馆

The Association between the C5263T Mutation in the Mitochondrial ND2 Gene and Coronary Heart Disease among young Chinese han People

引用

Biomedical and Environmental Sciences 2017年第4期30卷 280-287页

作者： han Guo Xin XIA Lei LI Shuo Shuo JIN Qin Hua SONG Yang SHEN Hong WANG Li Li KONG Ling Jie LI Tan Shi ZHU Hai Yan Emergency Department General Hospital of Chinese PLABeijing 100853China Medical Support Department General Hospital of Chinese PLABeijing 100853China Cardiology Department of Chinese PLA Beijing 100853China

Objective This study aimed to investigate the genetic background of mitochondrial genes in young patients with Coronary heart disease （CHD） to provide a foundation for the early prevention of young patients with CHD. Methods 115 cases of young （〈 45 years） CHD Chinese han patients （case group）, 100 cases of older （〉 45 years） Chinese Hart CHD patients （experimental group） hospitalized and 100 cases of healthy people through physical examination （control group） at the General Hospital of PLA between January 2014 and December 2015 were selected. General information, clinical assessment, pedigree analysis, and mitochondrial full sequence scanning were performed. The pedigrees of one patient harbouring the C5263T mutation were recruited. Mitochondrial functional analysis including cellular reactive oxygen species （ROS） levels and mitochondrial membrane potential （MMP） were performed on pedigrees with the C5263T mutation （mutation group） and without the mutation （non-mutation group）. Results The differences in biochemical tests （P 〉 0.05） between the case group and experimental group were not significant. The C5263T single-nucleotide mutation of the mitochondrial ND2 gene was observed in 2 young CHD patients in the case group. The premature CHD of these 2 patients followed a pattern of maternal inheritance. The mutation group （11, 112） had higher ROS levels （4750.82±1045.55 vs. 3888.58 ± 487.60, P= 0.022） and lower MMP levels （P= 0.045） than the non-mutation group （II1, III1, III2）. Conclusion We speculated that the mitochondrial C5263T mutation might be associated with the occurrence CHD in Chinese Hart young people.

关键词： Mitochondrion Coronary heart disease young

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Enhancement of Performance by Blade Optimization in Two-Stage Ring Blower

引用

Journal of Thermal Science 2010年第5期19卷 383-389页

作者： Choon-Man Jang Gi-young han Plant Research Division Korea Institute of Construction Technology dh-m co. ltd.626-5Bulmo-dongSeo-guIncheon404-270Korea

This paper describes the shape optimization of an impeller used for two-stage high pressure ring *** shape variables,which are used to define an impeller shape,are introduced to increase the blower *** pressure of a blower is selected as an object function,and the blade optimization is performed by a response surface ***-dimensional Navier-Stokes equations are introduced to analyze the internal flow of the blower and to find the value of object function for the training *** good agreement between experimental measurements and numerical simulation is obtained in the present *** the shape optimization,it is found that a hub height is effective to increase pressure in the ring *** pressure rise for the optimal two-stage ring blower is successfully increased up to 1.86% compared with that of reference at the design flow *** recirculation flow having low velocity is formed in both sides of the impeller outlet by different flow direction of the inlet and outlet of the *** flow field inside the ring blower is also analyzed and discussed.

关键词： Ring blower Blower performance Numerical simulation Blade optimization Response surface method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Organic solar cells for indoor power generation

引用

Science China Chemistry 2020年第1期63卷 1-2页

作者： Hwa Sook Ryu han young Woo Department of Chemistry College of Science Korea University

During last decades,organic solar cells(OSCs)have achieved remarkable advancements via extensive studies on the optimization of photovoltaic donor/acceptor(D/A)materials,device fabrication,and the D/A bulk heterojunction *** conversion efficiencies(PCEs)up to〜16%for single junction cells and over 17%PCEs were successfully demonstrated for tandem OSC devices[1,2].OSCs may find real industrial applications soon,including building integrated photovoltaics,portable power sources and indoor power generation for low power consumption electronic devices(i.e.,internet of things(IOT)sensors).Among them,indoor applications have great potentials because OSCs can convert indoor lights into electricity more efficiently compared to inorganic counterparts[3].

关键词： D/A power portable

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Semi-crystalline photovoltaic polymers with siloxane-terminated hybrid side-chains

引用

Science China Chemistry 2017年第4期60卷 528-536页

作者： Yuxiang Li Seyeong Song Song Yi Park Jin young Kim han young WOO Department of Cogno-Mechatronics Engineering Pusan National University Miryang 627-706 Republic of Korea Department of Energy and Chemical Engineering Ulsan National Institute of Science and Technology Ulsan 689-798 Republic of Korea Department of Chemistry Korea University Seoul 136-713 Republic of Korea

Three types of semi-cry stalline photovoltaic polymers were synthesized by incorporating a siloxane-terminated organic/inorganic hybrid side-chain and changing the number of fluorine substituents.A branch point away from a polymer main backbone in the siloxane-containing side-chains and the intra-and/or interchain noncovalent coulombic interactions enhance a chain planarity and facile interchain *** resulting polymers formed strongly agglomerated films with high roughness,suggesting strong intermolecular *** optical band gap of ca.1.7 eV was measured for all polymers with a pronounced shoulder peak due to tight π-π *** increasing the fluorine substituents,the frontier energy levels decreased and preferential face-on orientation was *** siloxane-terminated side-chains and fluorine substitution promoted the intermolecular packing,showing well resolved lamellar scatterings up to(300) for this series of polymers in the grazing incidence wide angle X-ray scattering *** PPsiDTBT,PPsiDTFBT and PPsiDT2 FBT devices showed a power conversion efficiency of 3.16%,4.40%and 5.65%,respectively,by blending with PC_(71)***-type bimolecular charge recombination was similar for three polymeric solar *** main loss in the photocurrent generation for PPsiDTBT:PC_(71)BM was interpreted to originate from the trap assisted charge recombination by measuring light-intensity dependent short-circuit current density(J_(SC)) and open-circuit voltage(V_(Oc)).Our results provide a new insight into the rational selection of solubilizing substituents for optimizing crystalline interchain packing with appropriate miscibility with PC71 BM for further optimizing polymer solar cells.

关键词： siloxane side-chain fluorine substitution semi-crystalline charge transport

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

THE PHYSICAL PROPERTIES OF POLY(2-HYDROXYETHYL METHACRYLATE)COPOLYMER HYDROGELS USED AS INTRAVAGINAL RINGS

引用

Chinese Journal of Polymer Science 2009年第3期27卷 359-366页

作者： young a han Eun Mi Lee Byung Chul Ji Department of Textile System Engineering Kyungpook National UniversityDaegu 702-701Korea Department of Advanced Organic Materials Science and Engineering Kyungpook National UniversityDaegu 702-701Korea

Poly(2-hydroxyethyl methacrylate)(PHEMA)and poly(2-hydroxyethyl methacrylate-co-sodium methacrylate) [P(HEMA-co-SMA)]hydrogels with different compositions were prepared to be used as intravaginal rings,and their gelation time,water content,mechanical properties and morphology were *** water content of PHEMA and P(HEMA-co-SMA) hydrogels decreased as the concentration of the monomer and the degree of crosslinking increased,while the water content significantly increased as the content of SMA,the hydrophilic monomer,*** increasing of the concentration of the crosslinking agent affected the tensile and flexural properties *** presence of a proper small amount of SMA also led the tensile and flexural modulus to move to a higher *** results showed that P(HEMA-co-SMA) hydrogel with high drug load and good mechanical properties at optimum preparation conditions can be prepared for intravaginal rings to deliver nonhormonal *** results may be applied to prepare better intravaginal drug delivery devices.

关键词： PHEMA and P(HEMA-co-SMA)hydrogels Tensile and flexural properties High drug load Intravaginal drug delivery devices.

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Dendritic Nanostructured Waste Copper Wires for High-Energy Alkaline Battery

引用

Nano-Micro Letters 2020年第1期12卷 1-12页

作者： Nilesh RChodankar Su‑Hyeon Ji young‑Kyu han Do‑Heyoung Kim School of Chemical Engineering Chonnam National UniversityGwangju 500‑757South Korea Department of Energy and Materials Engineering Dongguk UniversitySeoul 100‑715Republic of Korea

Rechargeable alkaline batteries(RABs)have received remarkable attention in the past decade for their high energy,low cost,safe operation,facile manufacture,and ecofriendly *** date,expensive electrode materials and current collectors were predominantly applied for RABs,which have limited their real-world *** the present work,we propose a scalable process to utilize electronic waste(e-waste)Cu wires as a cost-effective current collector for high-energy wire-type ***,the vertically aligned CuO nanowires were prepared over the waste Cu wires via in situ alkaline ***,both atomiclayer-deposited NiO and NiCo-hydroxide were applied to the CuO nanowires to form a uniform dendritic-structured NiCo-hydroxide/NiO/CuO/Cu *** the prepared dendritic-structured electrode was applied to the RAB,it showed excellent electrochemical features,namely high-energy-density(82.42 Wh kg−1),excellent specific capacity(219 mAh g−1),and long-term cycling stability(94%capacity retention over 5000 cycles).The presented approach and material meet the requirements of a cost-effective,abundant,and highly efficient electrode for advanced eco-friendly *** importantly,the present method provides an efficient path to recycle e-waste for value-added energy storage applications.

关键词： Alkaline batteries Dendritic nanostructure NiCo-hydroxide Waste Cu wires

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

High-efficiency organic solar cells enabled by an alcohol-washable solid additive

引用

Science China Chemistry 2021年第12期64卷 2161-2168页

作者： Yuanpeng Xie Hwa Sook Ryu Lili han Yunhao Cai Xiaopeng Duan Donghui Wei han young Woo Yanming Sun School of Chemistry Beihang UniversityBeijing100191China Department of Chemistry College of ScienceKU-KIST Graduate School of Converging Science and TechnologyKorea UniversitySeoul136-713Korea College of Chemistry and Molecular Engineering Zhengzhou UniversityZhengzhou450001China

The solvent additive strategy has been widely utilized to boost the power conversion efficiency(PCE)of organic solar cells(OSCs).However,the residual solvent additive in the active layer tends to induce a gradual morphology degradation and further influences the long-term stability of ***,a solid additive,1,4-diiodobenzene(DIB),was introduced to fabricate efficient *** found that the treatment of DIB can lead to optimized morphology to form a bicontinuous network with intensified intermolecular packing in the donor and acceptor ***,DIB can be easily removed from the active layer via a simple alcohol washing process and no further post-thermal annealing is needed,which is desirable for large-scale manufacturing of *** a result,high efficiencies of 17.47%for PM6:Y6 and 18.13%(certified as 17.7%)for PM6:BTP-eC9 binary OSCs are achieved,which are among the highest efficiencies reported for binary OSCs thus ***,OSCs fabricated with DIB also exhibit superior stability compared with the as-cast and traditional solvent additive processed ***,DIB was successfully applied in different active layers,manifesting its general *** work provides a feasible approach to enhance both the efficiency and stability of OSCs.

关键词： organic solar cells solid additive alcohol washing process efficiency stability

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Gastric ischemia after epinephrine injection in a patient with liver cirrhosis

引用

World Journal of Gastroenterology 2013年第3期19卷 411-414页

作者： Su young Kim Seung-Hee han Kyung han Kim Sang Ock Kim Sang-young han Sung-Wook Lee Yang Hyun Baek Department of Internal Medicine Dong-A University College of MedicineBusan 602-715South Korea

Endoscopic epinephrine injection is relatively easy,quick and ***,it has a low rate of com-plications,and it is widely used for the management of nonvariceal upper gastrointestinal *** have been several case reports of gastric ischemia after en-doscopic injection *** intra-arterial in-jection may result in either spasm or thrombosis,leading to subsequent tissue ischemia or necrosis,although the stomach has a rich vascular supply and the vascular reserve of the intramural *** addition to endoscopic injection therapy,smoking,hypertension and atherosclerosis are risk factors of gastric ischemia. We report a case of gastric ischemia after submucosal epinephrine injection in a 51-year-old woman with hy-pertension and liver cirrhosis.

关键词： Hematemesis Epinephrine Gastric ischemia Liver cirrhosis Hypertension

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Heteroatom substitution-induced asymmetric A–D–A type non-fullerene acceptor for efficient organic solar cells

引用

Journal of Energy Chemistry 2020年第1期29卷 144-150,I0006页

作者： Chao Lia Jiali Song Yunhao Cai Guangchao han Wenyu Zheng Yuanping Yi Hwa Sook Ryu han young Woo Yanming Sun School of Chemistry Beihang UniversityBeijing 100191China Beijing National Laboratory for Molecular Science Key Laboratory of Organic SolidsInstitute of ChemistryChinese Academy of SciencesBeijing 100190China Department of Chemistry College of ScienceKorea UniversitySeoul 136-713Republic of Korea

Research on asymmetric A–D–A structured non-fullerene acceptors has lagged far behind the development of symmetric *** this contribution,by simply replacing one sulfur atom in indacenodithiophene unit with a selenium atom,an asymmetric building block Se PT and a corresponding asymmetric non-fullerene acceptor Se PT-IN have been *** Se PT-IN achieved a high efficiency of 10.20% in organic solar cells when blended with PBT1-C,much higher than that of symmetric TPT-IN counterpart(8.91%).Our results demonstrated an effective heteroatom substitution strategy to develop asymmetric A–D–A structured non-fullerene acceptors.

关键词： Asymmetric non-fullerene acceptors Heteroatom substitution Organic solar cells Power conversion efficiency

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma

引用

World Journal of Gastroenterology 2012年第26期18卷 3426-3434页

作者： Yang Hyun Baek Kyoung Tae Kim Sung Wook Lee Jin Sook Jeong Byeong Ho Park Kyung Jin Nam Jin han Cho young Hoon Kim young Hoon Roh Hyung Sik Lee young Min Choi Sang young han Department of Internal Medicine Dong-A University College of MedicineBusan 602-103South Korea Department of Pathology Dong-A University College of MedicineBusan 602-103South Korea Department of Radiology Dong-A University College of MedicineBusan 602-103South Korea Department of Surgery Dong-A University College of MedicineBusan 602-103South Korea Department of Radiation Oncology Dong-A University College of MedicineBusan 602-103South Korea

AIM:To investigate the efficacy of hepatic arterial infusion chemotherapy(HAIC) using floxuridine(FUDR) in patients with advanced hepatocellular carcinoma(HCC) confined to the ***:Thirty-four patients who had advanced HCC with unresectability or unsuccessful previous therapy in the absence of extrahepatic metastasis were treated with intra-arterial FUDR chemotherapy at ourhospital between March 2005 and May *** the 34 patients,9 patients were classified as Child class C,and 18 patients had portal vein tumor thrombus(PVTT).One course of chemotherapy consisted of continuous infusion of FUDR(0.3 mg/kg during day 1-14) and dexamethasone(10 mg on day 1,4,7 and 11),and this treatment was repeated every 28 ***:Two patients(5.9%) displayed a complete response,and 12 patients(35.3%) had a partial *** tumor control rate was 61.8%.The median overall survival times were 15.3 mo,12.4 mo and 4.3 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0392).The progression-free survival was 12.9 mo,7.7 mo and 2.6 mo for the patients who were classified as Child class A,Child class B and Child class C,respectively(P = 0.0443).The cumulative survival differed significantly according to the Child-Pugh classification and the presence of *** addition to hepatic reserve capacity and PVTT,the extent of HCC was an independent factor in determining a poor *** most common adverse reactions to HAIC were mucositis,diarrhea and peptic ulcer disease,but most of these complications were improved by medical treatment and/or a delay of ***:The present study demonstrates that intra-arterial FUDR chemotherapy is a safe and effective treatment for advanced HCC that is recalcitrant to other therapeutic modalities,even in patients with advanced cirrhosis.

关键词： Hepatic arterial infusion chemotherapy Floxuridine Advanced hepatocellular carcinoma Child-Pugh classification Portal vein tumor thrombus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：